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Cited by 51Alcohol Consumption and Health EffectsSubstance Abuse Treatment and OutcomesHealthcare Systems and Public Health

Population drinking and liver cirrhosis mortality: is there a link in eastern Europe?

Ramstedt, Mats·2007·Addiction
DOI 10.1111/j.1360-0443.2007.01872.x
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Abstract

Aims To analyse the relationship between population drinking and liver cirrhosis mortality in eastern European countries and compare it with similar findings from western Europe. Design and measurements Yearly data, from the approximate period 1960–2002, on liver cirrhosis mortality in total and by gender were analysed in relation to per capita alcohol consumption in nine eastern European countries divided into ‘spirits countries’ and ‘non‐spirits countries’. The Box–Jenkins technique for time–series analysis was used to estimate the impact on liver cirrhosis resulting from a 1‐litre increase in per capita consumption in terms of relative (%) and absolute effects (number of cirrhosis deaths). Findings Cirrhosis mortality rates were related significantly to population drinking in eight of nine eastern European countries and both relative and absolute alcohol effects laid within the range of previous western European estimates. A 1‐litre increase in per capita consumption was on average estimated to cause three to four additional cirrhosis deaths per 100 000 for men and one additional death for women. The absolute effects for men were relatively high in a European perspective: stronger than in mid‐ and northern Europe and only marginally weaker in comparison with southern Europe. Conclusions A reduction in per capita alcohol consumption would prevent many cirrhosis deaths in eastern Europe, particularly for men. It is suggested that further studies of the extent other forms of alcohol‐related mortality respond to changes in population drinking in eastern Europe would be valuable.

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  • The comparatively short lag between national alcohol consumption levels and changes in cirrhosis mortality is probably related to the effects of alcohol on patients with subclinical compensated liver cirrhosis.

    “While alcohol generally requires several years to induce fibrosis in the liver, the comparatively short lag between national alcohol consumption levels and changes in cirrhosis mortality is probably related to the effects of alcohol on patients with subclinical compensated liver cirrhosis [4,38,51].”

    From Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis (2014) · cites this paper as [51]

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Authors
Ramstedt, M.
Affiliations
Stockholm University (SE)
Corresponding author
Ramstedt, Mats
ORCID
Ramstedt, Mats
Venue
Addiction
Publisher
Wiley
Published
2007-07-06
Volume
102
Issue
8
Pages
1212-1223
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
DOI
10.1111/j.1360-0443.2007.01872.x
OpenAlex
W2094922358
Cited by
51
References
34
Citations by year
2025: 2 · 2024: 2 · 2023: 5 · 2022: 1 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 6 · 2014: 3 · 2013: 4 · 2012: 2
FWCI
3.30
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
Funders
Forskningsrådet för Arbetsliv och Socialvetenskap
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Keywords
cirrhosis mortality, alcohol consumption, per capita alcohol consumption, alcohol-related mortality, spirits consumption, sex differences in mortality, Eastern Europe, Western Europe comparison, alcohol policy
MeSH terms
Alcohol Drinking, Europe, Eastern, Female, Humans, Liver Cirrhosis, Male, Age Distribution, Sex Distribution

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