Cited by 88Alcohol Consumption and Health EffectsSubstance Abuse Treatment and OutcomesForensic Toxicology and Drug Analysis

Could the high level of cirrhosis in central and eastern Europe be due partly to the quality of alcohol consumed? An exploratory investigation

Open access
Sz cs, Sándor, Sárváry, Attila, McKee, Martin, Ádány, Róza·2005·Addiction

Abstract

Background The burden of alcohol‐related diseases differs widely among countries. Since the 1980s, a band of countries in Central and Eastern Europe have experienced a steep rise in deaths from chronic liver diseases and cirrhosis. A possible risk factor is the consumption of illegally produced home‐made spirits in these countries containing varying amounts of aliphatic alcohols and which may be hepatotoxic. However, little is known about the composition of such beverages. Aims To compare the concentration of short‐chain aliphatic alcohols in spirits from illegal and legal sources in Hungary. Design Samples taken from commercial retailers and illegal sources were collected and their aliphatic patterns and alcohol concentrations were determined by gas chromatographic/mass spectrometric (GC/MS) analysis. Findings The concentrations of methanol, isobutanol, 1‐propanol, 1‐butanol, 2‐butanol and isoamyl alcohol were significantly higher in home‐made spirits than those of from commercial sources. Conclusions The results suggest that the consumption of home‐made spirits is an additional risk factor for the development of alcohol‐induced cirrhosis and may have contributed to high level of liver cirrhosis mortality in Central and Eastern Europe. Restrictions on supply and sale of alcohol from illicit sources are needed urgently to reduce significantly the mortality from chronic liver disease.

Integrity signals

Registry

Crossref · 10.1111/j.1360-0443.2005.01009.x

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Another dimension of alcohol use discussed specifically for liver cirrhosis is the quality of the alcoholic beverage, and particularly potential problems with hepatotoxic ingredients in unrecorded consumption.

    “Another dimension of alcohol use has been discussed specifically for liver cirrhosis: the quality of the alcoholic beverage, and particularly potential problems with hepatotoxic ingredients in unrecorded consumption (e.g. 286.”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Sz cs, S., Sárváry, A., McKee, M., & Ádány, R.
Affiliations
  • University of Debrecen (HU)
  • London School of Hygiene & Tropical Medicine (GB)
Corresponding author
Ádány, Róza
Venue
Addiction
Publisher
Wiley
Published
2005-03-22
Volume
100
Issue
4
Pages
536-542
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W2066388051
Cited by
88
References
40
Citations by year
2026: 1 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 3 · 2017: 6 · 2016: 1 · 2015: 4 · 2014: 3 · 2013: 11 · 2012: 7
FWCI
3.34
Type
journal article
Language
en
Open access
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
  • University of Debrecen Electronic Archive (University of Debrecen) (submittedVersion, other-oa)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (submittedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
Keywords
liver cirrhosis, aliphatic alcohols, methanol, isobutanol, chronic liver disease, alcohol-related mortality, Central and Eastern Europe, hepatotoxicity
MeSH terms
Alcohol Drinking, Alcoholic Beverages, Chromatography, Gas, Female, Humans, Hungary, Liver Cirrhosis, Alcoholic, Male, Risk Factors, Mass Spectrometry

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review