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Socio-demographic risk factors for alcohol and drug dependence: the 10-year follow-up of the national comorbidity survey
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AIMS: Continued progress in etiological research and prevention science requires more precise information concerning the specific stages at which socio-demographic variables are implicated most strongly in transition from initial substance use to dependence. The present study examines prospective associations between socio-demographic variables and the subsequent onset of alcohol and drug dependence using data from the National Comorbidity Survey (NCS) and the NCS Follow-up survey (NCS-2). DESIGN: The NCS was a nationally representative survey of the prevalence and correlates of DSM-III-R mental and substance disorders in the United States carried out in 1990-2002. The NCS-2 re-interviewed a probability subsample of NCS respondents a decade after the baseline survey. Baseline NCS socio-demographic characteristics and substance use history were examined as predictors of the first onset of DSM-IV alcohol and drug dependence in the NCS-2. PARTICIPANTS: A total of 5001 NCS respondents were re-interviewed in the NCS-2 (87.6% of baseline sample). FINDINGS: Aggregate analyses demonstrated significant associations between some baseline socio-demographic variables (young age, low education, non-white ethnicity, occupational status) but not others (sex, number of children, residential area) and the subsequent onset of DSM-IV alcohol or drug dependence. However, conditional models showed that these risk factors were limited to specific stages of baseline use. Moreover, many socio-demographic variables that were not significant in the aggregate analyses were significant predictors of dependence when examined by stage of use. CONCLUSIONS: The findings underscore the potential for socio-demographic risk factors to have highly specific associations with different stages of the substance use trajectory.
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“In reality, the influence of cultural factors is highly nuanced, even impacting substance use trajectories by geographic location within a national origin group (Swendsen et al., 2009).”
From Assessment of culture and environment in the Adolescent Brain and Cognitive Development Study: Rationale, description of measures, and early data (2018) · cites this paper as Swendsen et al., 2009
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“In reality, the influence of cultural factors is highly nuanced, even impacting substance use trajectories by geographic location within a national origin group (Swendsen et al., 2009).”
Background
Metadata
- Authors
- Swendsen, J., Conway, K. P., Degenhardt, L., Dierker, L., Glantz, M., Jin, R., Merikangas, K. R., Sampson, N., & Kessler, R. C.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- National Institutes of Health (US)
- National Drug and Alcohol Research Centre (AU)
- Wesleyan University (US)
- Harvard University (US)
- Corresponding author
- Swendsen, Joel
- ORCID
- Venue
- Addiction
- Publisher
- Wiley
- Published
- 2009-07-13
- Volume
- 104
- Issue
- 8
- Pages
- 1346-1355
- ISSN
- 0965-2140 (ISSN-L)
- 1360-0443
- PMC
- PMC2794245
- OpenAlex
- W2137453755
- Cited by
- 139
- References
- 70
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 3 · 2023: 5 · 2022: 12 · 2021: 8 · 2020: 26 · 2019: 10 · 2018: 4 · 2017: 2 · 2016: 7 · 2015: 7 · 2014: 9 · 2013: 5 · 2012: 14
- FWCI
- 7.39
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Addiction (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Robert Wood Johnson Foundation
- John D. and Catherine T. MacArthur Foundation
- John W. Alden Trust
- World Health Organization
- National Institutes of Health (5r13mh066849-04, 5r01mh069864-04, 5r01mh070884-05)
- Substance Abuse and Mental Health Services Administration
- Johnson and Johnson
- Pan American Health Organization
- National Institute of Mental Health (R13-MH-066849, ZIAMH002806, R01‐MH070884, R01MH046376, R01MH077883, Z01MH002806, U01MH060220, R01‐MH069864)
- National Institute on Drug Abuse (R01DA016558, R01DA012058)
- Fogarty International Center (R03TW006481)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- alcoholism, drug addiction, sociodemographic risk factors, substance use onset, National Comorbidity Survey, DSM-IV, low educational attainment, young age, occupational status
- MeSH terms
- Adolescent, Adult, Epidemiologic Methods, Female, Humans, Male, United States, Comorbidity, Substance-Related Disorders, Alcohol-Related Disorders, Diagnostic and Statistical Manual of Mental Disorders, Young Adult
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