Cited by 147Substance Abuse Treatment and OutcomesOpioid Use Disorder TreatmentHIV, Drug Use, Sexual Risk

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Evaluating the impact of community‐based treatment options on methamphetamine use: findings from the Methamphetamine Treatment Evaluation Study (MATES)

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McKetin, Rebecca, Najman, Jake M., Baker, Amanda L., Lubman, Dan I., Dawe, Sharon, Ali, Robert, Lee, Nicole K., Mattick, Richard P., Mamun, Abdullah·2012·Addiction

DOI 10.1111/j.1360-0443.2012.03933.x

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Abstract

Aims: To evaluate the impact of community‐based drug treatment on methamphetamine use using inverse probability of treatment‐weighted (IPTW) estimators to derive treatment effects. Design: A longitudinal prospective cohort study with follow‐ups at 3 months, 1 year and 3 years. Treatment effects were derived by comparing groups at follow‐up. IPTW estimators were used to adjust for pre‐treatment differences between groups. Setting: S ydney and B risbane, A ustralia. Participants: Participants were methamphetamine users entering community‐based detoxification (n = 112) or residential rehabilitation (n = 248) services and a quasi‐control group of methamphetamine users (n = 101) recruited from the community. Measurements: Frequency of methamphetamine use between interviews (no use, less than weekly, 1–2 days per week, 3+ days per week), continuous abstinence from methamphetamine use, past month methamphetamine use and methamphetamine dependence. Findings: Detoxification did not reduce methamphetamine use at any follow‐up relative to the quasi‐control group. Relative to quasi‐control and detoxification groups combined, residential rehabilitation produced large reductions in the frequency of methamphetamine use at 3 months [odds ratio (OR) = 0.23, 95% confidence interval (CI) 0.15–0.36, P < 0.001), with a marked attenuation of this effect at 1 year (OR 0.62, 95% CI 0.40–0.97, P = 0.038) and 3 years (OR = 0.71, 95% CI 0.42–1.19, P = 0.189). The greatest impact was for abstinence: for every 100 residential rehabilitation clients there was a gain of 33 being continuously abstinent at 3 months, with this falling to 14 at 1 year and 6 at 3 years. Conclusions: Community‐based residential rehabilitation may produce a time‐limited decrease in methamphetamine use, while detoxification alone does not appear to do so.

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Authors: McKetin, R., Najman, J. M., Baker, A. L., Lubman, D. I., Dawe, S., Ali, R., Lee, N. K., Mattick, R. P., & Mamun, A.
Affiliations: Australian National University (AU)
The University of Queensland (AU)
University of Newcastle Australia (AU)
Eastern Health (AU)
Griffith University (AU)
The University of Adelaide (AU)
Flinders University (AU)
UNSW Sydney (AU)
Corresponding author: McKetin, Rebecca
ORCID: McKetin, Rebecca
Najman, Jake M.
Baker, Amanda L.
Lubman, Dan I.
Dawe, Sharon
Ali, Robert
Lee, Nicole K.
Mamun, Abdullah
Venue: Addiction
Publisher: Wiley
Published: 2012-07-12
Volume: 107
Issue: 11
Pages: 1998-2008
ISSN: 0965-2140 (ISSN-L)
1360-0443
DOI: 10.1111/j.1360-0443.2012.03933.x
OpenAlex: W1924347018
Cited by: 147
References: 35
Citations by year: 2026: 2 · 2025: 14 · 2024: 16 · 2023: 10 · 2022: 7 · 2021: 12 · 2020: 9 · 2019: 11 · 2018: 14 · 2017: 14 · 2016: 15 · 2015: 8 · 2014: 9 · 2013: 5 · 2012: 1
FWCI: 5.51
Type: journal article
Language: en
Open access: green
hdl.handle.net
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Addiction (publishedVersion)
PubMed (publishedVersion)
NOVA (University of Newcastle Australia) (submittedVersion)
Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
eSpace (Curtin University) (submittedVersion)
Figshare (submittedVersion)
ANU Open Research (Australian National University) (submittedVersion)
Griffith Research Online (submittedVersion)
Funders: Australian Government
University of New South Wales
Medical Research Council
National Health and Medical Research Council
National Drug and Alcohol Research Centre
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Keywords: methamphetamine use, community-based drug treatment, residential rehabilitation, detoxification, treatment effects, abstinence, methamphetamine dependence, addiction treatment, inverse probability of treatment weighting
MeSH terms: Adult, Female, Humans, Longitudinal Studies, Male, Methamphetamine, Recurrence, Residential Treatment, Case-Control Studies, Treatment Outcome, Amphetamine-Related Disorders

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Evaluating the impact of community‐based treatment options on methamphetamine use: findings from the Methamphetamine Treatment Evaluation Study (MATES)

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