CoChat
Sign Up
Cited by 108

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Review article: drug‐induced liver injury in clinical practice

Björnsson, E.·2010·Alimentary Pharmacology & Therapeutics
DOI 10.1111/j.1365-2036.2010.04320.x
Open this paper in CoChat — free account

Abstract

Aliment Pharmacol Ther 2010; 32: 3–13 Summary: Background Drug‐induced liver injury (DILI) is an important differential diagnosis in many patients in clinical hepatology. DILI is the leading cause of acute liver failure and is an important safety issue when new drugs are developed. Aims To provide a review of the recent data on DILI with particular focus on the most common and relevant issues seen in clinical practice. Methods A Medline search was undertaken to identify relevant literature using search terms including ‘drug‐induced liver injury’ and ‘hepatotoxicity’. Results The true incidence of DILI remains unknown but incidence up to 14 cases per 100 000 inhabitants and year has been reported. Antibiotics, analgesics and NSAIDs are the most common drugs causing liver injury. Idiosyncratic DILI has been shown to have a dose‐dependent component and drugs without significant hepatic metabolism rarely cause DILI. Chronic elevation in liver enzymes can develop after DILI but this is rarely associated with clinical morbidity or mortality. Conclusions Drug‐induced liver injury remains a diagnostic challenge. Multicentre studies and international collaborative work with well‐characterized patients will increase our understanding of liver injury associated with drugs. New therapies for acute liver failure resulting from drugs are needed.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/j.1365-2036.2010.04320.x

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The estimated DILI incidence in mainland China (23.80 per 100,000) was higher than that estimated in Iceland (19.1/100,000), France (13.9/100,000), the United States (2.7/100,000), Spain (3.42/100,000) and Sweden (2.4/100,000).

    “which was still higher than that estimated in Iceland (19.1/100,000) 7 , France (13.9/100,000), 9 the United states (2.7/100,000), 10 Spain (3.42/100,000) 21 and Sweden (2.4/100,000) 22 (Table 4).”

    From Incidence and Etiology of Drug-Induced Liver Injury in Mainland China (2019) · cites this paper as [7]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 93

  1. 10.2165/00002018-200932010-00005 · DOI · Paper page
  2. 10.1002/hep.22272 · DOI
  3. 10.1055/s-2002-30105 · DOI
  4. 10.1053/jhep.2002.34857 · DOI
  5. 10.1111/j.1365-2036.2006.03117.x · DOI
  6. 10.1111/j.1365-2125.2004.02133.x · DOI
  7. 10.1111/j.0954-6820.1967.tb10873.x · DOI
  8. Malchow‐Møller A, 1981, Causes and characteristics of 500 consecutive causes of jaundice, Scand J Gastroenterol, 16, 1
  9. 10.1136/gut.48.3.409 · DOI
  10. 10.1080/00365520310000492 · DOI
  11. Vuppalanchi R, 2006, Etiology of new‐onset jaundice: how often is it caused by idiosyncratic drug‐induced liver injury in the united states, Am J Gastroenterol, 101, 1
  12. 10.1007/s00228-004-0888-z · DOI
  13. 10.1111/j.1365-2036.2007.03355.x · DOI
  14. 10.1016/j.jhep.2008.10.021 · DOI · Paper page
  15. 10.1016/j.gastro.2005.05.006 · DOI
  16. 10.1111/j.1365-2036.2007.03330.x · DOI
  17. Zimmerman H, 1999, Hepatotoxicity the adverse effects of drugs and other chemicals on the liver
  18. 10.2165/00002018-200528040-00006 · DOI
  19. 10.1111/j.1440-1746.2007.05207.x · DOI
  20. 10.1016/j.jhep.2005.12.016 · DOI
  21. 10.1111/j.1600-0404.2008.01009.x · DOI
  22. 10.1053/jhep.2001.21083 · DOI
  23. 10.1086/313680 · DOI
  24. 10.1002/hep.21324 · DOI
  25. 10.1002/hep.20800 · DOI · Paper page
  26. 10.1080/01926230590888306 · DOI
  27. 10.2165/11535340-000000000-00000 · DOI
  28. 10.1016/0895-4356(93)90101-6 · DOI · Paper page
  29. 10.1055/s-0029-1240003 · DOI
  30. 10.1053/j.gastro.2008.09.011 · DOI
  31. 10.1055/s-0029-1240005 · DOI
  32. 10.1002/hep.22446 · DOI
  33. 10.1055/s-0029-1240011 · DOI
  34. 10.1007/s00431-009-0927-y · DOI
  35. 10.1136/gut.2006.114363 · DOI
  36. 10.1016/S0016-5085(03)00938-7 · DOI
  37. 10.1016/S0016-5085(19)32568-5 · DOI
  38. 10.1002/hep.1840050617 · DOI
  39. 10.1016/j.dld.2005.06.004 · DOI
  40. 10.1016/j.jhep.2005.11.027 · DOI
  41. Gayle F, 2008, Steatohepatitis due to antiretroviral therapy, West Indian Med J, 57, 66
  42. 10.1097/QAD.0b013e3280fa81cb · DOI
  43. 10.1016/j.cgh.2008.04.023 · DOI
  44. 10.1002/lt.20204 · DOI · Paper page
  45. 10.1016/S0168-8278(02)00231-3 · DOI
  46. 10.1111/j.1872-034X.2008.00486.x · DOI · Paper page
  47. 10.1097/MCG.0b013e31818a3854 · DOI · Paper page
  48. 10.1136/gut.44.5.731 · DOI
  49. 10.1002/hep.21424 · DOI · Paper page
  50. 10.1053/jhep.2001.20645 · DOI · Paper page
  51. 10.1146/annurev.pharmtox.47.120505.105150 · DOI
  52. 10.1002/hep.22895 · DOI · Paper page
  53. 10.1002/hep.23317 · DOI
  54. 10.1016/j.cgh.2009.03.034 · DOI
  55. 10.1002/hep.1840080327 · DOI
  56. 10.3748/wjg.v11.i34.5394 · DOI
  57. 10.1016/S0002-9343(05)80060-9 · DOI
  58. 10.1136/bmj.1.5854.655 · DOI
  59. Yeung E, 2003, Ramipril‐associated hepatotoxicity, Arch Pathol Lab Med, 127, 1493, 10.5858/2003-127-1493-RH · DOI
  60. Mazeika PK, 1989, Chronic active hepatitis associated with diclofenac sodium therapy, Br J Clin Pract, 43, 125, 10.1111/j.1742-1241.1989.tb08690.x · DOI
  61. 10.1016/S0016-5085(77)80141-8 · DOI
  62. 10.1016/0168-8278(92)90029-O · DOI
  63. 10.1016/S0168-8278(99)80362-6 · DOI
  64. 10.1016/0016-5085(86)90887-5 · DOI
  65. 10.3109/00365528109181815 · DOI
  66. Tonder M, 1974, Sulfonamide‐induced chronic liver disease, Scand J Gastroenterol, 9, 93, 10.1080/00365521.1974.12096796 · DOI
  67. 10.1159/000198941 · DOI
  68. 10.7326/0003-4819-80-1-1 · DOI
  69. 10.1016/S0168-8278(87)80039-9 · DOI
  70. Johnston DE, 1997, Chronic hepatitis related to use of fluoxetine, Am J Gastroenterol, 92, 1225
  71. Volbeda F, 2004, Liver cirrhosis due to chronic use of nitrofurantoin, Ned Tijdschr Geneeskd, 31, 148
  72. 10.1136/bmj.1.6127.1591 · DOI
  73. 10.1053/j.gastro.2009.06.006 · DOI · Paper page
  74. 10.1016/0168-8278(88)80027-8 · DOI
  75. 10.1136/gut.20.7.620 · DOI
  76. Dechene A, 2005, Effectiveness of a steroid and ursodexycholic acid combination therapy with drug‐induced subacute liver failure, Hepatology, 42, 358A
  77. 10.1002/hep.23588 · DOI · Paper page
  78. 10.1080/15563650902752376 · DOI
  79. 10.1002/hep.20948 · DOI
  80. 10.1016/j.cca.2008.01.018 · DOI
  81. 10.1097/01.mjt.0000140217.48324.e3 · DOI
  82. 10.1016/j.cgh.2008.02.053 · DOI
  83. 10.1016/S1089-3261(05)70025-8 · DOI
  84. 10.1097/00004836-198802000-00016 · DOI
  85. 10.1001/jama.296.1.87 · DOI
  86. 10.1001/jama.1994.03520230055038 · DOI · Paper page
  87. 10.1002/hep.20300 · DOI
  88. 10.1053/jhep.2002.32148 · DOI
  89. 10.1002/hep.22536 · DOI · Paper page
  90. 10.1001/archinte.161.18.2247 · DOI
  91. 10.1097/01.mjt.0000140216.40700.95 · DOI
  92. 10.1080/15563650701447020 · DOI
  93. Shayiq RM, 1999, Repeat exposure to incremental doses of acetaminophen (paracetamol) provides protection against acetaminophen‐lethality in mice: an explanantion for high acetaminophen dosage in humans, Hepatology, 31, 777

Cited by

Sorted by citations

Metadata

Authors
Björnsson, E.
Venue
Alimentary Pharmacology & Therapeutics
Publisher
Wiley
Published
2010-06-03
Volume
32
Issue
1
Pages
3-13
ISSN
  • 0269-2813
  • 1365-2036
DOI
10.1111/j.1365-2036.2010.04320.x
Cited by
108
References
1
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review