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Cited by 393

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Liver transplantation for acute liver failure from drug induced liver injury in the United States

Russo, Mark W., Galanko, Joseph A., Shrestha, Roshan, Fried, Michael W., Watkins, Paul·2004·Liver Transplantation
DOI 10.1002/lt.20204
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Abstract

Studies of acute liver failure from drugs have included cases mostly attributed to acetaminophen (APAP) but have reported limited data on other drugs. We used the United Network for Organ Sharing (UNOS) liver transplant database from 1990 to 2002 to identify recipients and estimate a U.S. population-based rate of liver transplantation due to acute liver failure from drugs. Patients were identified if their diagnosis was acute hepatic necrosis from an implicated drug at the time of transplant. Liver transplantation for drug hepatotoxicity accounted for 15% of liver transplants for acute liver failure over the study period. In our cohort (n = 270), 206 (76%) recipients were female. APAP alone, or in combination with another drug, accounted for 133 (49%) cases. In the non-acetaminophen (non-APAP) group (n = 137), the most frequently implicated drugs were: isoniazid, n = 24 (17.5%); propylthiouracil, n = 13 (9.5%); and phenytoin and valproate in 10 (7.3%) cases each. One-year patient and graft survival for the entire cohort was 77 and 71%, respectively. Among Caucasians (n = 206) and African-Americans (n = 48), APAP only was implicated in 110 (53%) patients and 12 (25%) patients, respectively, and non-APAP drugs were implicated in 96 (47%) patients and 36 (75%) patients, respectively (P = .0004). Among African-Americans in the non-APAP group, 28 (78%) were women. In conclusion four drugs were implicated in 42% of patients undergoing liver transplantation for acute liver failure due to drugs other than APAP. The increased frequency of African-American women undergoing liver transplantation for non-APAP drug induced liver injury warrants further study. (Liver Transpl 2004;10:1018-1023.)

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Crossref · 10.1002/lt.20204

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2 of 2 references verified0 citation errors · 0 not checkable

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  • In western studies, acute liver failure was most associated with use of non-steroidal anti-inflammatory drugs (NSAIDs), anti-infective drugs, and herbs and dietary supplements (HDS).

    “As reported by the western studies, acute liver failure was most associated with use of non-steroidal anti-inflammatory drugs (NSAIDs), anti-infective drugs, and herbs and dietary supplements (HDS).13,33,34”

    From Incidence and Etiology of Drug-Induced Liver Injury in Mainland China (2019) · cites this paper as [33]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 22

  1. Schiodt, 1999, Etiology and outcome for 295 patients with acute liver failure in the United States., Liver Transpl Surg, 5, 2934, 10.1002/lt.500050102 · DOI
  2. Ostapowicz, 2002, Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States., Ann Intern Med, 137, 947954, 10.7326/0003-4819-137-12-200212170-00007 · DOI · Paper page
  3. Kaplowitiz, 2001, Drug-induced liver disorders: implications for drug development and regulation., Drug Saf, 24, 483490
  4. Friis, 1992, Drug-induced hepatic injury: an analysis of 1100 cases reported to The Danish Committee on Adverse Drug Reactions between 1978 and 1987., J Intern Med, 232, 133138, 10.1111/j.1365-2796.1992.tb00562.x · DOI
  5. Sgro, 2002, Incidence of drug-induced hepatic injuries: a french population-based study., Hepatol, 36, 451455, 10.1053/jhep.2002.34857 · DOI
  6. Miller, 1974, Hospital admissions due to adverse drug reactions., Arch Intern Med, 134, 219223, 10.1001/archinte.1974.00320200029002 · DOI
  7. Rakela, 1985, Fulminant hepatitis. Mayo Clinic experience with 34 cases., May Clin Proc, 60, 289292, 10.1016/S0025-6196(12)60534-5 · DOI
  8. Shakil, 2000, Acute liver failure: clinical features, outcomes analysis, and applicability of prognostic criteria., Liver Transpl, 6, 163169
  9. Lewis, 1989, Drug-induced liver disease., Med Clin North Am, 73, 775792, 10.1016/S0025-7125(16)30638-1 · DOI
  10. Nolan, 1999, Hepatotoxicity associated with isoniazid preventive therapy. A 7-year survey from a public health tuberculosis clinic., JAMA, 281, 10141018, 10.1001/jama.281.11.1014 · DOI
  11. Dickenson, 1981, Risk factors for isoniazid-induced liver dysfunction., J Clin Gastroenterol, 3, 271279
  12. Steele, 1991, Toxic hepatitis with isoniazid and rifampin: a meta-analysis., Chest, 99, 465471, 10.1378/chest.99.2.465 · DOI
  13. Larrey, 2000, Drug-induced liver diseases., J Hepatol, 32, 7788
  14. Williams, 1997, Fifty years of experience with propylthiouracil-associated hepatotoxicity: what have we learned?, J Clin Endocrinol Metab, 82, 17271733
  15. Bryant, 1996, Valproic acid hepatic fatalities. III. U.S. experience since 1986., Neurology, 46, 465469, 10.1212/WNL.46.2.465 · DOI
  16. Meyers, 1994, Acute hepatic failure in seven patients after prophylaxis and therapy with antituberculous agents. Successful treatment with orthotopic liver transplantation., Transplantation, 58, 372377, 10.1097/00007890-199408000-00022 · DOI
  17. Bell, 1992, Treatment of valproic acid-associated hepatic failure with orthotopic liver transplantation., Ann Pharmacother, 26, 1821, 10.1177/106002809202600104 · DOI
  18. Annegers, 1999, The incidence of epilepsy and unprovoked seizures in multiethnic, urban health maintenance organizations., Epilepsia, 40, 502506, 10.1111/j.1528-1157.1999.tb00748.x · DOI
  19. Alander, 2000, Pediatric acetaminophen overdose: risk factors associated with hepatocellular injury., Arch Pediatr Adolesc Med, 154, 346350, 10.1001/archpedi.154.4.346 · DOI
  20. Tolman, 2002, The liver and lovastatin., Am J Cardiol, 89, 13741380, 10.1016/S0002-9149(02)02355-X · DOI
  21. Russo, 2003, How to use statins in patients with chronic liver disease., Cleve Clin J Med, 17, 5862
  22. Russman, 2001, Kava hepatotoxicity., Ann Intern Med, 135, 6869, 10.7326/0003-4819-135-1-200107030-00036 · DOI

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Metadata

Authors
Russo, M. W., Galanko, J. A., Shrestha, R., Fried, M. W., & Watkins, P.
Venue
Liver Transplantation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2004-08
Volume
10
Issue
8
Pages
1018-1023
ISSN
1527-6465
DOI
10.1002/lt.20204
Cited by
393
References
2
Language
en
Licence
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 4048 d)

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