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Cited by 260

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Vitamin D, PTH and calcium levels in pregnant women and their neonates

Bowyer, Lucy, Catling‐Paull, Christine, Diamond, Terrence, Homer, Caroline, Davis, Gregory, Craig, Maria E.·2009·Clinical Endocrinology

Abstract

Summary: Objectives To determine the prevalence of vitamin D deficiency in pregnant women and their neonates and to examine factors associated with vitamin D deficiency. Design and patients Population‐based study of pregnant women and their neonates from South‐eastern Sydney, Australia. Measurements Serum 25 hydroxy‐vitamin D (25‐OHD), PTH, calcium, albumin, phosphate and alkaline phosphatase were measured in women at 23–32 weeks gestation and on cord blood at delivery. Maternal skin phototype was recorded using the Fitzpatrick scale. Results Vitamin D deficiency (defined as 25‐OHD ≤ 25 nmol/l) was found in 144 of 971 (15%) women and 98 of 901 (11%) neonates. Median 25‐OHD was 52 nmol/l (range 17–174) in mothers and 60 nmol/l (17–245) in neonates. Maternal 25‐OHD levels varied by season, with lowest levels in late winter/early spring (P < 0·001). Factors associated with maternal vitamin D deficiency in multiple logistic regression were (OR, 95% CI): maternal birthplace outside Australia: 2·2 (1·4–3·5, P = 0·001), dark skin phototype: 2·7 (1·6–4·5, P < 0·001), wearing a veil: 21·7 (11·7–40·3, P < 0·001) and younger maternal age: 0·93 (0·89–0·97, P = 0·001). Maternal vitamin D deficiency increased the risk of neonatal vitamin D deficiency (OR 17·2, 95% CI 8·8–34·3) and birth weight was lower among infants of deficient vs. sufficient mothers: mean (SD) 3245 g (545) vs. 3453 g (555), P < 0·001. Conclusions Vitamin D deficiency is common among pregnant women; immigrant, veiled and dark skinned women are at greatest risk. Maternal vitamin D deficiency increases the risk of neonatal vitamin D deficiency and lower birth weight.

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Metadata

Authors
Bowyer, L., Catling‐Paull, C., Diamond, T., Homer, C., Davis, G., & Craig, M. E.
Venue
Clinical Endocrinology
Publisher
Wiley
Published
2009-02-11
Volume
70
Issue
3
Pages
372-377
ISSN
  • 0300-0664 (ISSN-L)
  • 1365-2265
OpenAlex
W2039388975
Cited by
260
References
32
FWCI
5.90
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Vitamin D, PTH and calcium levels in pregnant women and their neonates. https://app.cochat.ai/papers/10.1111/j.1365-2265.2008.03316.x
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Bowyer, L., Catling‐Paull, C., Diamond, T., Homer, C., Davis, G., & Craig, M. E. (2009). Vitamin D, PTH and calcium levels in pregnant women and their neonates. Clinical Endocrinology. https://doi.org/10.1111/j.1365-2265.2008.03316.x

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