Quality of life in men receiving radiotherapy and neo‐adjuvant androgen deprivation for prostate cancer: results from a prospective longitudinal study
Open accessAbstract
Aim. To report a study measuring the quality of life and side effects in men receiving radiotherapy and hormone ablation for prostate cancer up to 1 year after treatment. Background. Prostate cancer incidence is increasing with the result that more men are living longer with the disease and the side effects of treatment. It is important to know the effects this has on their quality of life. Design. Survey. Method. Between September 2006–September 2007, all men who were about to undergo radical conformal radiotherapy ± neo‐adjuvant androgen deprivation for localized prostate cancer were invited to participate in the study; 149 men were recruited. They completed the European Organization on Research and Treatment of Cancer quality of life questionnaire C‐30 and Prostate Cancer module PR25 at four time‐points. Results. At 4–6 weeks after radiotherapy, participants experienced the biggest relative decline in global quality of life, social, physical, and role functioning and an increase in treatment side effects. At 6 months postradiotherapy the majority of men experienced an improvement in their side effects. However, a minority of men were experiencing severe side effects of radiotherapy at 1 year post‐treatment. Single men and men who had a low quality of life prior to radiotherapy, reported a lower quality of life at 1 year after treatment in comparison to married men. Conclusion. Men with prostate cancer suffer limitations due to the symptoms they experience and disruption to their quality of life. It is essential that nurses develop and deliver follow‐up care which is flexible and appropriate to the individual needs of these men.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Men are less likely to express emotions through venting [68].
“Given that men are less likely to express emotions through venting [68], it is not surprising that females reported higher scores for this coping strategy.”
From Psychological variables associated with quality of life in patients with head and neck cancer: the role of body image distress (2022) · cites this paper as [68]
The Conceptual framework discusses coping with prostate cancer, and the Discussion reports changes in men’s quality of life, but neither addresses whether men are less likely than women to express emotions through venting. Searches for “venting” and emotional expression found no passage making that comparison. Page numbers were unavailable in our copy. (LLM, conf=0.75)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007) · Behavior Research Methods · doi:10.3758/bf03193146 · Cited by 65,971 · see citing works
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., Filiberti, A., Flechtner, H., Fleishman, S. B., Haes, J. C. J. M. D., et al. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.5.365 · Cited by 16,005 · see citing works
Species Richness of Parasite Assemblages: Evolution and Patterns
Poulin, R. (1997) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.ecolsys.28.1.341 · Cited by 3,500 · see citing works
Fayers, P. M., Aaronson, N. K., Bjordal, K., Groenvold, M., Curran, D., & Bottomley, A. (2001) · Research at the University of Copenhagen (University of Copenhagen) · Cited by 2,520 · see citing works
Spss Survival Manual: A Step By Step Guide To Data Analysis Using Spss For Windows (version 10)
Pallant, J. (2001) · Cited by 1,529 · see citing works
Quality of life in cancer patients--an hypothesis.
Calman, K. C. (1984) · Journal of Medical Ethics · doi:10.1136/jme.10.3.124 · Cited by 1,134 · see citing works
Quality-of-life outcomes in men treated for localized prostate cancer
Litwin, M. S., Hays, R. D., Fink, A., Ganz, P. A., Leake, B., Leach, G. E., & Brook, R. H. (1995) · JAMA · doi:10.1001/jama.1995.03520260051032 · Cited by 1,020 · see citing works
Pilepich, M. V., Winter, K. A., Lawton, C. A., Krisch, R. E., Wolkov, H. B., Movsas, B., Hug, E. B., Asbell, S. O., & Grignon, D. J. (2005) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2004.08.047 · Cited by 912 · see citing works
Quality of Life: The Assessment, Analysis and Interpretation of Patient‐Reported Outcomes
Fayers, P. M., & Machin, D. (2007) · doi:10.1002/9780470024522 · Cited by 865 · see citing works
Bullinger, M. (1995) · Social Science & Medicine · doi:10.1016/0277-9536(95)00115-n · Cited by 763 · see citing works
Esper, P., Mo, F., Chodak, G., Sinner, M., Cella, D., & Pienta, K. J. (1997) · Urology · doi:10.1016/s0090-4295(97)00459-7 · Cited by 696 · cited 2× · see citing works
“The FACT-P focuses less on the specific side effects of prostate cancer treatment and more on the functional domains of quality of life (Esper et al. 1997).”
BackgroundMethodHanks, G. E., Pajak, T. F., Porter, A. T., Grignon, D. J., Brereton, H. D., Venkatesan, V., Horwitz, E. M., Lawton, C. A., Rosenthal, S. A., Sandler, H. M., et al. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.11.023 · Cited by 688 · see citing works
Potosky, A. L., Davis, W. W., Hoffman, R. M., Stanford, J. L., Stephenson, R. A., Penson, D. F., & Harlan, L. C. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh259 · Cited by 680 · see citing works
Risk Factors for Urinary Incontinence after Radical Prostatectomy
Eastham, J. A., Kattan, M. W., Rogers, E. T., Goad, J. R., Ohori, M., Boone, T. B., & Scardino, P. T. (1996) · The Journal of Urology · doi:10.1016/s0022-5347(01)65488-0 · Cited by 527 · see citing works
Wei, J. T., Dunn, R. L., Sandler, H. M., McLaughlin, P. W., Montie, J. E., Litwin, M. S., NYQUIST, L. V., & Sanda, M. G. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.20.2.557 · Cited by 443 · see citing works
Litwin, M. S., Lubeck, D. P., Henning, J. M., & Carroll, P. R. (1998) · The Journal of Urology · doi:10.1016/s0022-5347(01)63222-1 · Cited by 401 · see citing works
Miller, D. C., Sanda, M. G., Dunn, R. L., Montie, J. E., Pimentel, H., Sandler, H. M., McLaughlin, W. P., & Wei, J. T. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.07.116 · Cited by 383 · see citing works
Prostate cancer and health‐related quality of life: a review of the literature
Eton, D. T., & Lepore, S. J. (2002) · Psycho-Oncology · doi:10.1002/pon.572 · Cited by 346 · see citing works
Quality of Life in Cancer: Definition, Purpose, and Method of Measurement
Cella, D. F., & Tulsky, D. S. (1993) · Cancer Investigation · doi:10.3109/07357909309024860 · Cited by 332 · see citing works
Laverdière, J., Gomez, J., Cusan, L., et al. (1997) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(96)00513-5 · Cited by 313 · see citing works
Lintz, K. C., Moynihan, C., Steginga, S. K., Norman, A. R., Eeles, R. A., Huddart, R. A., Dearnaley, D. P., & Watson, M. (2003) · Psycho-Oncology · doi:10.1002/pon.702 · Cited by 271 · see citing works
[Measuring quality of life in palliative care].
Ferreira, P. L., Barros, A. P., & Brito, A. B. (2008) · PubMed · Cited by 254 · see citing works
Wei, J. T., Dunn, R. L., Sandler, H. M., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.20.2.557 · Cited by 240 · see citing works
Time Course and Predictors of Symptoms After Primary Prostate Cancer Therapy
Talcott, J. A., Manola, J. B., Clark, J. A., Kaplan, I. D., Beard, C. J., MITCHELL, S. P., Chen, R. C., O’Leary, M. P., Kantoff, P. W., & D'Amico, A. V. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.01.199 · Cited by 222 · see citing works
Patients’ Perceptions of Quality of Life After Treatment for Early Prostate Cancer
Clark, J. A., Inui, T. S., Silliman, R. A., Bokhour, B. G., Krasnow, S. H., Robinson, R. A., Spaulding, M. B., & Talcott, J. A. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.02.115 · Cited by 210 · see citing works
Osoba, D., Aaronson, N. K., Zee, B. C.-Y., Sprangers, M. A. G., & Velde, A. T. (1997) · Quality of Life Research · doi:10.1023/a:1026429831234 · Cited by 204 · see citing works
Measuring quality of life in palliative care.
Cella, D. F. (1995) · PubMed · Cited by 201 · see citing works
Korfage, I. J., Essink‐Bot, M., Borsboom, G., Madalinska, J. B., Kirkels, W. J., Habbema, J. D. F., Schröder, F. H., & de Koning, H. J. (2005) · International Journal of Cancer · doi:10.1002/ijc.21043 · Cited by 196 · see citing works
Penson, D. F., Feng, Z., Kuniyuki, A. A., McLerran, D., Albertsen, P. C., Deapen, D., Gilliland, F. D., Hoffman, R. M., Stephenson, R. A., Potosky, A. L., et al. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.07.139 · Cited by 190 · see citing works
Ferrer, M., Suárez, J. F., Guedea, F., Fernández, P., Macías, V., Mariño, A., Hervas, A., Herruzo, I., Ortiz, M. J., Villavicencio, H., et al. (2008) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2007.12.024 · Cited by 181 · see citing works
Roach, M., Lu, J., Pilepich, M. V., et al. (2000) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(00)00577-0 · Cited by 179 · see citing works
The clinical significance of quality of life assessments in oncology: a summary for clinicians
Sloan, J. A., Frost, M. H., Berzon, R., Dueck, A., Guyatt, G., Moinpour, C., Sprangers, M., Ferrans, C., Cella, D., & Clinical Significance Consensus Meeting Group (2006) · Supportive Care in Cancer · doi:10.1007/s00520-006-0085-y · Cited by 149 · see citing works
The Swedish Health-Related Quality of Life Survey (SWED-QUAL)
Brorsson, B., Ifver, J., & Hays, R. D. (1993) · Quality of Life Research · doi:10.1007/bf00642887 · Cited by 143 · see citing works
Baravelli, C. M., Krishnasamy, M., Pezaro, C., Schofield, P. E., Lotfi‐Jam, K., Rogers, M., Milne, D., Aranda, S. K., King, D. X., Shaw, B., et al. (2009) · Journal of Cancer Survivorship · doi:10.1007/s11764-009-0086-1 · Cited by 121 · see citing works
Roy, S. C. (1984) · AJN American Journal of Nursing · doi:10.1097/00000446-198410000-00057 · Cited by 107 · see citing works
Sigurdard�ttir, V., Bolund, C., Brandberg, Y., & Sullivan, M. (1993) · Quality of Life Research · doi:10.1007/bf00435223 · Cited by 94 · see citing works
Quality of life in prostate cancer patients
Herr, H. W. (1997) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.47.4.207 · Cited by 88 · see citing works
The natural history of prostate cancer
Kessler, B., & Albertsen, P. C. (2003) · Urologic Clinics of North America · doi:10.1016/s0094-0143(02)00182-9 · Cited by 87 · see citing works
Bergman, B., Sullivan, M., & Sörenson, S. (1992) · Acta Oncologica · doi:10.3109/02841869209088260 · Cited by 86 · see citing works
Bansal, M., Mohanti, B. K., Shah, N., et al. (2004) · Quality of Life Research · doi:10.1023/b:qure.0000018491.80646.bc · Cited by 85 · see citing works
Hoffman, R. M., Gilliland, F. D., Penson, D. F., Stone, S. N., Hunt, W. C., & Potosky, A. L. (2004) · Cancer · doi:10.1002/cncr.20608 · Cited by 64 · see citing works
Quality of Life for Men With Prostate Cancer
Katz, A. (2007) · Cancer Nursing · doi:10.1097/01.ncc.0000281726.87490.f2 · Cited by 62 · see citing works
Quality of life measurements: a soft outcome--or is it?
Frost, M. H., & Sloan, J. A. (2002) · PubMed · Cited by 61 · see citing works
Supportive care in radiotherapy
Faithfull, S., & Wells, M. (2003) · Open Research (University of Surrey) · Cited by 61 · see citing works
Tarrant, C., Sinfield, P., Agarwal, S., & Baker, R. (2008) · BMC Health Services Research · doi:10.1186/1472-6963-8-65 · Cited by 57 · see citing works
Habermehl, D., Brecht, I. C., Bergmann, F., et al. (2013) · Radiation Oncology · doi:10.1186/1748-717x-8-27 · Cited by 57 · see citing works
Monga, U., Kerrigan, A. J., Thornby, J. A., Monga, T. N., & Zimmermann, K. P. (2005) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2004.06.0071 · Cited by 54 · see citing works
Pinkawa, M., Holý, R., Piroth, M. D., et al. (2010) · Radiation Oncology · doi:10.1186/1748-717x-5-27 · Cited by 53 · see citing works
Movsas, B., Scott, C., & Bruner, D. W. (2006) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2006.01.004 · Cited by 50 · see citing works
Hoffman, R. M., Barry, M. J., Stanford, J. L., et al. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.06.072 · Cited by 49 · see citing works
Quality of life of men treated for localized prostate cancer: outcomes at 6 and 12 months
Lev, E. L., Eller, L. S., Gejerman, G., Kolassa, J. E., Colella, J., Pezzino, J., Lane, P., Munver, R., Esposito, M., Scheuch, J., et al. (2008) · Supportive Care in Cancer · doi:10.1007/s00520-008-0493-2 · Cited by 48 · see citing works
Involvement ofINK4A gene products in the pathogenesis and development of human osteosarcoma
Benassi, M. S., Molendini, L., Gamberi, G., Magagnoli, G., Ragazzini, P., Gobbi, G., Sangiorgi, L., Pazzaglia, L., Asp, J., Brantsing, C., et al. (2001) · Cancer · doi:10.1002/1097-0142(20011215)92:12 · Cited by 47 · see citing works
Faithfull, S. (1995) · European Journal of Cancer Care · doi:10.1111/j.1365-2354.1995.tb00087.x · Cited by 46 · see citing works
Lips, I. M., van Gils, C. H., van der Heide, U. A., et al. (2009) · British Journal of Urology · doi:10.1111/j.1464-410x.2008.08117.x · Cited by 35 · see citing works
Galalae, R. M., Loch, T., Riemer, B., et al. (2004) · Strahlentherapie und Onkologie · doi:10.1007/s00066-004-1254-x · Cited by 31 · see citing works
Geinitz, H., Thamm, R., Scholz, C. W., Heinrich, C., Prause, N., Kerndl, S., Keller, M., Busch, R. M., Molls, M., & Zimmermann, F. B. (2009) · Strahlentherapie und Onkologie · doi:10.1007/s00066-009-2023-7 · Cited by 30 · see citing works
Quality of life in patients with prostate cancer
McPherson, C. P., Swenson, K. K., & Kjellberg, J. L. (2001) · Seminars in Oncology Nursing · doi:10.1016/s0749-2081(01)80021-8 · Cited by 29 · see citing works
External beam radiation therapy for prostate cancer
Horwitz, E. M., & Hanks, G. E. (2000) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.50.6.349 · Cited by 29 · see citing works
van Andel, G., Visser, A. P., Zwinderman, A. H., et al. (2003) · The Prostate · doi:10.1002/pros.10342 · Cited by 27 · see citing works
Tärnhuvud, M., Wändel, C., & Willman, A. (2007) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2007.01.004 · Cited by 21 · see citing works
Quality of life among men treated with radiation therapy for prostate cancer.
Ward-Smith, P. A., & Kapitan, D. (2005) · PubMed · Cited by 12 · see citing works
Hashine, K., Azuma, K., Koizumi, T., & Sumiyoshi, Y. (2005) · International Journal of Clinical Oncology · doi:10.1007/s10147-004-0455-8 · Cited by 11 · see citing works
Neues zur Lebensqualität in der urologischen Onkologie
Doehn, C., Doehn, C., Jocham, D., et al. (2003) · Oncology Research and Treatment · doi:10.1159/000074743 · Cited by 9 · see citing works
Radiotherapy. What do patients need to know?
Eardley, A. (1986) · PubMed · Cited by 5 · see citing works
Stage as major long term outcome predictor in minor salivary gland carcinoma
Lutgendorf (2000) · Pure Amsterdam UMC · doi:10.1002/1097-0142(20000915)89:6 · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- Beauchamp T. & Childress J. (1994) Principles of Biomedical Ethics, 4th edn. Oxford University Press.
- Eble J.N., Sauter G., Epstein J.I. & Sesterhenn I.A. (eds) (2004) World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. IARC Press, Lyon.
- Janda M., Gerstner N., Obermair A., Fuerst A., Wachter S., Dieck- mann K. & Potter R. (2000) Quality of life changes during con- formal radiation therapy for prostate carcinoma. American Journal of Cancer 89(6), 1322-1328.
Cited by
Sorted by citations
McCaughan, E., Prue, G., McSorley, O., Northouse, L., Schafenacker, A., & Parahoo, K. (2013) · Journal of Advanced Nursing · doi:10.1111/jan.12132 · Cited by 23 · see citing works
Self-citationCerea, S., Sansoni, M., Scarzello, G., Groff, E., & Ghisi, M. (2022) · Supportive Care in Cancer · doi:10.1007/s00520-022-07334-6 · Cited by 15 · see citing works
- Authors
- Mc Caughan, E., Mc Sorley, O., Prue, G., Parahoo, K., Bunting, B., Sullivan, J. O., & McKenna, H.
- Affiliations
- University of Ulster (GB)
- Belfast City Hospital (GB)
- Venue
- Journal of Advanced Nursing
- Publisher
- Wiley
- Published
- 2012-03-27
- Volume
- 69
- Issue
- 1
- Pages
- 53-65
- ISSN
- 0309-2402 (ISSN-L)
- 1365-2648
- OpenAlex
- W1890410698
- Cited by
- 23
- References
- 65
- Citations by year
- 2022: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 2 · 2015: 2 · 2014: 3 · 2013: 5
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Advanced Nursing (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (Queen's University Belfast) (submittedVersion)
- Funders
- Medical Research Council (MR/K023241/1)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
- Keywords
- prostate cancer, quality of life, radiotherapy, androgen deprivation therapy, treatment side effects, EORTC QLQ-C30, social functioning, marital status, follow-up care, nursing care
- MeSH terms
- Aged, Androgen Antagonists, Combined Modality Therapy, Humans, Longitudinal Studies, Male, Middle Aged, Prostatic Neoplasms, Quality of Life
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
