The DOI matches its Crossref record; 362 of the 362 references it cites were found in a registry or an index.
Apoptosis: a basic biological phenomenon with wide‐ranging implications in human disease
Open accessAbstract
Abstract.: Apoptosis is a highly regulated process of cell deletion and plays a fundamental role in the maintenance of tissue homeostasis in the adult organism. Numerous studies in recent years have revealed that apoptosis is a constitutive suicide programme expressed in most, if not all cells, and can be triggered by a variety of extrinsic and intrinsic signals. Many human diseases can be attributed directly or indirectly to a derangement of apoptosis, resulting in either cell accumulation, in which cell eradication or cell turnover is impaired, or cell loss, in which the apoptotic programme is inadvertently triggered. In addition, defective macrophage engulfment and degradation of cell corpses may also contribute to a dysregulation of tissue homeostasis. An increased understanding of the signalling pathways that govern the execution of apoptosis and the subsequent clearance of dying cells may thus yield novel targets for therapeutic intervention in a wide range of human maladies.
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Cites
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Apoptosis in the Pathogenesis and Treatment of Disease
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Environmental toxicity, oxidative stress and apoptosis: Ménage à Trois
Franco, R., Sánchez-Olea, R., Reyes-Reyes, E. M., & Panayiotidis, M. I. (2009) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2008.11.012 · Cited by 541
Maia, L. B., & Moura, J. J. G. (2014) · Chemical Reviews · doi:10.1021/cr400518y · Cited by 401
Programmed cell death and its role in inflammation
Yang, Y., Jiang, G., Zhang, P., & Fan, J. (2015) · Military Medical Research · doi:10.1186/s40779-015-0039-0 · Cited by 290
Recent advances in our understanding of neurodegeneration
Jellinger, K. A. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0240-y · Cited by 274
Basova, L. V., Kurnikov, I. V., Wang, L., Ritov, V. B., Belikova, N. A., Vlasova, I. I., Pacheco, A. A., Winnica, D. E., Peterson, J., Bayir, H., et al. (2007) · Biochemistry · doi:10.1021/bi061854k · Cited by 212
Metadata
- Authors
- FADEEL, B., & ORRENIUS, S.
- Venue
- Journal of Internal Medicine
- Publisher
- Wiley
- Published
- 2005-11-14
- Volume
- 258
- Issue
- 6
- Pages
- 479-517
- ISSN
- 0954-6820 (ISSN-L)
- 1365-2796
- OpenAlex
- W1997219075
- Cited by
- 698
- References
- 362
- FWCI
- 14.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
