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Cited by 6,887

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Caspases: Enemies Within

Thornberry, Nancy A., Lazebnik, Yuri·1998·Science

Abstract

REVIEW Apoptosis, an evolutionarily conserved form of cell suicide, requires specialized machinery. The central component of this machinery is a proteolytic system involving a family of proteases called caspases. These enzymes participate in a cascade that is triggered in response to proapoptotic signals and culminates in cleavage of a set of proteins, resulting in disassembly of the cell. Understanding caspase regulation is intimately linked to the ability to rationally manipulate apoptosis for therapeutic gain.

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Metadata

Authors
Thornberry, N. A., & Lazebnik, Y.
Venue
Science
Published
1998-08-28
Volume
281
Issue
5381
Pages
1312-1316
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2061497413
Cited by
6,887
References
1
FWCI
177.05
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Caspases: Enemies Within. https://app.cochat.ai/papers/10.1126/science.281.5381.1312
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Thornberry, N. A., & Lazebnik, Y. (1998). Caspases: Enemies Within. Science. https://doi.org/10.1126/science.281.5381.1312

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