Aging young sleep: A test of the phase advance hypothesis of sleep disturbance in the elderly
Open accessAbstract
With aging, the phase relationship between sleep and body core temperature is altered such that the temperature minimum occurs substantially earlier in the major nocturnal sleep period. The sleep maintenance difficulties that often accompany normal aging are generally assumed to be associated with this age-related change in the phase angle between sleep and temperature. To test this notion, we used timed exposure to bright light to reproduce in healthy young adults a similar phase relationship between temperature and sleep, to determine if such a manipulation would induce the same fragmented nocturnal sleep commonly observed in individuals over 65 years of age. Seven young adults were exposed to morning bright light for 3 consecutive days following a baseline night. Bright light exposure caused a 97 min phase advance of the fitted temperature minimum when compared with baseline. Significant declines in several measures of sleep quality were associated with the phase advance, including wakefulness after initial sleep onset (WASO), sleep efficiency and number of stage changes. Yet, the severity of sleep disturbance exhibited by these subjects did not approach that exhibited by most elderly subjects. The findings suggest that while chronophysiological changes appear to be strongly associated with the tendency to awaken in the early morning, they cannot account entirely for the severity of sleep disturbance frequently observed in older subjects.
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Previous findings showed that bright-light exposure in the morning induced phase advances and earlier sleep onset.
“In addition to statistical issues, previous findings showed that bright-light exposure in the morning induced phase advances and earlier sleep onset [68,69].”
From Preliminary Results: The Impact of Smartphone Use and Short-Wavelength Light during the Evening on Circadian Rhythm, Sleep and Alertness (2021) · cites this paper as [68]
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- Authors
- CAMPBELL, S. S., & DAWSON, D.
- Affiliations
- Cornell University (US)
- Corresponding author
- CAMPBELL, SCOTT S.
- ORCID
- DAWSON, DREW
- Venue
- Journal of Sleep Research
- Publisher
- Wiley
- Published
- 1992-09
- Volume
- 1
- Issue
- 3
- Pages
- 205-210
- ISSN
- 0962-1105 (ISSN-L)
- 1365-2869
- OpenAlex
- W2046255386
- Cited by
- 55
- References
- 40
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 4 · 2020: 2 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 2 · 2013: 1
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Sleep Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Health Assistance Foundation
- National Institute of Mental Health
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- aging, sleep disorders, core body temperature, circadian rhythm, bright light exposure, sleep maintenance, wake after sleep onset, sleep efficiency, chronobiology, older adults
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