The genetic architecture of domestication in the chicken: effects of pleiotropy and linkage
Abstract
The extent of pleiotropy and epistasis in quantitative traits remains equivocal. In the case of pleiotropy, multiple quantitative trait loci are often taken to be pleiotropic if their confidence intervals overlap, without formal statistical tests being used to ascertain if these overlapping loci are statistically significantly pleiotropic. Additionally, the degree to which the genetic correlations between phenotypic traits are reflected in these pleiotropic quantitative trait loci is often variable, especially in the case of antagonistic pleiotropy. Similarly, the extent of epistasis in various morphological, behavioural and life-history traits is also debated, with a general problem being the sample sizes required to detect such effects. Domestication involves a large number of trade-offs, which are reflected in numerous behavioural, morphological and life-history traits which have evolved as a consequence of adaptation to selective pressures exerted by humans and captivity. The comparison between wild and domestic animals allows the genetic analysis of the traits that differ between these population types, as well as being a general model of evolution. Using a large F(2) intercross between wild and domesticated chickens, in combination with a dense SNP and microsatellite marker map, both pleiotropy and epistasis were analysed. The majority of traits were found to segregate in 11 tight 'blocks' and reflected the trade-offs associated with domestication. These blocks were shown to have a pleiotropic 'core' surrounded by more loosely linked loci. In contrast, epistatic interactions were almost entirely absent, with only six pairs identified over all traits analysed. These results give insights both into the extent of such blocks in evolution and the development of domestication itself.
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The long LD block brought a challenge to refining the causal loci of white plumage but provided an opportunity to investigate pleiotropy and linkage involved in breeding.
“The long LD block in the genomes brought challenge to refining the casual loci of white plumage, but provided an opportunity to investigate the pleiotropy and linkage involved in the breeding (Wright et al. 2010).”
From Genomic Analyses Unveil Helmeted Guinea Fowl (<i>Numida meleagris</i>) Domestication in West Africa (2021) · cites this paper as Wright et al. 2010
Cites
The genetical theory of natural selection
Fisher, R. A. (1930) · doi:10.5962/bhl.title.27468 · Cited by 17,617 · see citing works
Genetics and Analysis of Quantitative Traits
(2002) · Journal of Animal Breeding and Genetics · doi:10.1046/j.1439-0388.2002.00356.x · Cited by 6,172 · see citing works
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
Lander, E. S., & Kruglyak, L. (1995) · Nature Genetics · doi:10.1038/ng1195-241 · Cited by 5,196 · see citing works
Empirical threshold values for quantitative trait mapping.
Churchill, G. A., & Doerge, R. W. (1994) · Genetics · doi:10.1093/genetics/138.3.963 · Cited by 4,950 · see citing works
Waddington, C. H. (2014) · doi:10.4324/9781315765471 · Cited by 2,153 · see citing works
Grant, V. (1981) · Columbia University Press eBooks · doi:10.7312/gran92318 · Cited by 1,765 · see citing works
Whole-genome resequencing reveals loci under selection during chicken domestication
Rubin, C.-J., Zody, M. C., Eriksson, J., Meadows, J. R. S., Sherwood, E., Webster, M. T., Jiang, L., Ingman, M., Sharpe, T., Ka, S., et al. (2010) · Nature · doi:10.1038/nature08832 · Cited by 1,138 · see citing works
Self-citationPermutation Tests for Multiple Loci Affecting a Quantitative Character
Doerge, R. W., & Churchill, G. A. (1996) · Genetics · doi:10.1093/genetics/142.1.285 · Cited by 1,133 · see citing works
Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits
Hill, W. G., Goddard, M. E., & Visscher, P. M. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000008 · Cited by 1,039 · see citing works
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
Laere, A.-S. V., Nguyen, M. Q., Braunschweig, M., Nezer, C., Collette, C., Moreau, L., Archibald, A. L., Haley, C., Buys, N., Tally, M., et al. (2003) · Nature · doi:10.1038/nature02064 · Cited by 949 · see citing works
Self-citationEpistasis: too often neglected in complex trait studies?
Carlborg, Ö., & Haley, C. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1407 · Cited by 926 · see citing works
Habitat Selection Under Predation Hazard: Test of a Model with Foraging Minnows
Gilliam, J. F., & Fraser, D. F. (1987) · Ecology · doi:10.2307/1939877 · Cited by 880 · see citing works
Havenstein, G., Ferket, P., & Qureshi, M. (2003) · Poultry Science · doi:10.1093/ps/82.10.1500 · Cited by 861 · see citing works
Early canid domestication: the farm-fox experiment.
Trut, L. (1999) · American Scientist · doi:10.1511/1999.2.160 · Cited by 626 · see citing works
Domestic-animal genomics: deciphering the genetics of complex traits
Andersson, L., & Georges, M. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1294 · Cited by 622 · see citing works
Self-citationMolecular Characterization of the Major Wheat Domestication Gene Q
Simons, K. J., Fellers, J. P., Trick, H. N., Zhang, Z., Tai, Y.-S., Gill, B. S., & Faris, J. D. (2005) · Genetics · doi:10.1534/genetics.105.044727 · Cited by 615 · see citing works
Convergent Domestication of Cereal Crops by Independent Mutations at Corresponding Genetic Loci
Paterson, A. H., Lin, Y., Li, Z., Schertz, K. F., Doebley, J., Pinson, S. R. M., Liu, S., Stansel, J. W., & Irvine, J. E. (1995) · Science · doi:10.1126/science.269.5231.1714 · Cited by 614 · see citing works
GENETIC COVARIANCE OF FITNESS CORRELATES: WHAT GENETIC CORRELATIONS ARE MADE OF AND WHY IT MATTERS
Houle, D. (1991) · Evolution · doi:10.1111/j.1558-5646.1991.tb04334.x · Cited by 582 · see citing works
Advanced intercross lines, an experimental population for fine genetic mapping.
Darvasi, A., & Soller, M. (1995) · Genetics · doi:10.1093/genetics/141.3.1199 · Cited by 579 · see citing works
Clustering of housekeeping genes provides a unified model of gene order in the human genome
Lercher, M. J., Urrutia, A. O., & Hurst, L. D. (2002) · Nature Genetics · doi:10.1038/ng887 · Cited by 548 · see citing works
Identification of the Yellow Skin Gene Reveals a Hybrid Origin of the Domestic Chicken
Eriksson, J., Larson, G., Gunnarsson, U., Bed’Hom, B., Tixier‐Boichard, M., Strömstedt, L., Wright, D., Jungerius, A., Vereijken, A., Randi, E., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000010 · Cited by 544 · see citing works
Self-citationExperimental strategies for the genetic dissection of complex traits in animal models
Darvasi, A. (1998) · Nature Genetics · doi:10.1038/ng0198-19 · Cited by 540 · see citing works
Cohen, B. A., Mitra, R. D., Hughes, J. D., & Church, G. M. (2000) · Nature Genetics · doi:10.1038/79896 · Cited by 533 · see citing works
(1988) · Developments in crop science · doi:10.1016/c2009-0-00901-5 · Cited by 533 · see citing works
Crop Domestication as a Long‐Term Selection Experiment
Gepts, P. (2003) · Plant breeding reviews · doi:10.1002/9780470650288.ch1 · Cited by 457 · see citing works
Domestication of Plants in the Americas: Insights from Mendelian and Molecular Genetics
Pickersgill, B. (2007) · Annals of Botany · doi:10.1093/aob/mcm193 · Cited by 440 · see citing works
Genetic Control of the Domestication Syndrome in Common Bean
Koinange, E. M. K., Singh, S. P., & Gepts, P. (1996) · Crop Science · doi:10.2135/cropsci1996.0011183x003600040037x · Cited by 427 · see citing works
The Evolution of Host Specialization: Are Trade-Offs Overrated?
Fry, J. D. (1996) · The American Naturalist · doi:10.1086/285904 · Cited by 415 · see citing works
Genetic analysis of the morphological differences between maize and teosinte.
Doebley, J., & Stec, A. O. (1991) · Genetics · doi:10.1093/genetics/129.1.285 · Cited by 411 · see citing works
Social Cognitive Evolution in Captive Foxes Is a Correlated By-Product of Experimental Domestication
Hare, B., Plyusnina, I., Ignacio, N., Schepina, O., Stepika, A., Wrangham, R., & Trut, L. (2005) · Current Biology · doi:10.1016/j.cub.2005.01.040 · Cited by 347 · see citing works
Doebley, J., & Stec, A. O. (1993) · Genetics · doi:10.1093/genetics/134.2.559 · Cited by 336 · see citing works
Predators select against high growth rates and risk–taking behaviour in domestic trout populations
Biro, P. A., Abrahams, M. V., Post, J. R., et al. (2004) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2004.2861 · Cited by 316 · see citing works
Genetic Analysis of Sunflower Domestication
Burke, J. M., Tang, S., Knapp, S. J., & Rieseberg, L. H. (2002) · Genetics · doi:10.1093/genetics/161.3.1257 · Cited by 308 · see citing works
Pattern of diversity in the genomic region near the maize domestication gene tb1
Clark, R. M., Linton, E. W., Messing, J. W., & Doebley, J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2237049100 · Cited by 307 · see citing works
Groenen, M. A. M., Wahlberg, P., Foglio, M. H., Cheng, H. H., Megens, H., Crooijmans, R. P. M. A., Besnier, F., Lathrop, M. G., Muir, W. M., Wong, G. K., et al. (2008) · Genome Research · doi:10.1101/gr.086538.108 · Cited by 306 · see citing works
Self-citationQTL clusters reflect character associations in wild and cultivated rice
Cai, H., & Morishima, H. (2002) · Theoretical and Applied Genetics · doi:10.1007/s00122-001-0819-7 · Cited by 301 · see citing works
Cong, B., Liu, J., & Tanksley, S. D. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172520999 · Cited by 300 · see citing works
Epistasis and the release of genetic variation during long-term selection
Carlborg, Ö., Jacobsson, L., Åhgren, P., Siegel, P. B., & Andersson, L. (2006) · Nature Genetics · doi:10.1038/ng1761 · Cited by 292 · see citing works
Self-citationAnimal domestication and behavior
(2002) · doi:10.1079/9780851995977.0000 · Cited by 288 · see citing works
THE GENETICS OF ADAPTIVE SHAPE SHIFT IN STICKLEBACK: PLEIOTROPY AND EFFECT SIZE
Albert, A., Sawaya, S. M., Vines, T., Knecht, A. K., Miller, C. T., Summers, B. R., Balabhadra, S., Kingsley, D. M., & Schluter, D. (2007) · Evolution · doi:10.1111/j.1558-5646.2007.00259.x · Cited by 279 · see citing works
System-wide molecular evidence for phenotypic buffering in Arabidopsis
Fu, J., Keurentjes, J. J. B., Bouwmeester, H., America, T., Verstappen, F. W. A., Ward, J. L., Beale, M. H., de Vos, R. C. H., Dijkstra, M., Scheltema, R. A., et al. (2009) · Nature Genetics · doi:10.1038/ng.308 · Cited by 265 · see citing works
A Global Search Reveals Epistatic Interaction Between QTL for Early Growth in the ChickenPreprint
Carlborg, Ö., Kerje, S., Schütz, K. E., Jacobsson, L., Jensen, P., & Andersson, L. (2003) · Genome Research · doi:10.1101/gr.528003 · Cited by 252 · see citing works
Self-citationCoexpression of Neighboring Genes in the Genome of Arabidopsis thalianaPreprint
Williams, E. J. B., & Bowles, D. J. (2004) · Genome Research · doi:10.1101/gr.2131104 · Cited by 251 · see citing works
Kerje, S., Sharma, P. M., Gunnarsson, U., et al. (2004) · Genetics · doi:10.1534/genetics.104.027995 · Cited by 251 · see citing works
Self-citationPleiotropic scaling of gene effects and the ‘cost of complexity’
Wagner, G. P., Kenney‐Hunt, J. P., Pavličev, M., Peck, J. R., Waxman, D., & Cheverud, J. M. (2008) · Nature · doi:10.1038/nature06756 · Cited by 237 · see citing works
Long-Term Divergent Selection for Eight-Week Body Weight in White Plymouth Rock Chickens
DUNNINGTON, E. A., & Siegel, P. B. (1996) · Poultry Science · doi:10.3382/ps.0751168 · Cited by 231 · see citing works
Kerje, S., Carlborg, Ö., Jacobsson, L., Schütz, K. E., Hartmann, C., Jensen, P., & Andersson, L. (2003) · Animal Genetics · doi:10.1046/j.1365-2052.2003.01000.x · Cited by 229 · see citing works
Self-citationJohnsson, J. I., Petersson, E., Jönsson, E., et al. (1996) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/f96-090 · Cited by 224 · see citing works
Faris, J. D., Fellers, J. P., Brooks, S. A., & Gill, B. S. (2003) · Genetics · doi:10.1093/genetics/164.1.311 · Cited by 214 · see citing works
A tradeoff between immunocompetence and sexual ornamentation in domestic fowl
Verhulst, S., Dieleman, S. J., & Parmentier, H. K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.8.4478 · Cited by 212 · see citing works
Wright, D., Nakamichi, R., Krause, J., & Butlin, R. K. (2006) · Behavior Genetics · doi:10.1007/s10519-005-9029-4 · Cited by 205 · see citing works
Self-citationGenetical Genomics: Spotlight on QTL Hotspots
Rainer Breitling, A., Li, Y., Tesson, B. M., Fu, J., Wu, C., Wiltshire, T., Gerrits, A., Bystrykh, L. V., de Haan, G., Su, A. I., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000232 · Cited by 191 · see citing works
Zhang, L.-C., Ning, Z., Xu, G., et al. (2005) · Poultry Science · doi:10.1093/ps/84.8.1209 · Cited by 167 · see citing works
Carlborg, Ö., Andersson, L., & Kinghorn, B. P. (2000) · Genetics · doi:10.1093/genetics/155.4.2003 · Cited by 157 · see citing works
Self-citationAlbert, F. W., Shchepina, O., Winter, C., Römpler, H., Teupser, D., Palme, R., Ceglarek, U., Kratzsch, J., Sohr, R., Trut, L. N., et al. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.11.010 · Cited by 157 · see citing works
Schütz, K. E., Kerje, S., Carlborg, Ö., Jacobsson, L., Andersson, L., & Jensen, P. (2002) · Behavior Genetics · doi:10.1023/a:1020880211144 · Cited by 147 · see citing works
Self-citationFearfulness in red junglefowl and domesticated White Leghorn chickens
Campler, M. R., Jöngren, M., & Jensen, P. (2008) · Behavioural Processes · doi:10.1016/j.beproc.2008.12.018 · Cited by 142 · see citing works
Self-citationQxpak: a versatile mixed model application for genetical genomics and QTL analyses
Pérez‐Enciso, M., & Misztal, I. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth331 · Cited by 141 · see citing works
Effects of net blotch on growth and yield of spring barley
Deadman, M. L., & Cooke, B. M. (1987) · Annals of Applied Biology · doi:10.1111/j.1744-7348.1987.tb03230.x · Cited by 139 · see citing works
Schütz, K. E., Kerje, S., Jacobsson, L., Forkman, B., Carlborg, Ö., Andersson, L., & Jensen, P. (2003) · Behavior Genetics · doi:10.1023/b:bege.0000009481.98336.fc · Cited by 136 · see citing works
Self-citationGenetic architecture of tameness in a rat model of animal domestication
Albert, F. W., Carlborg, O., Plyusnina, I., Besnier, F., Hedwig, D., Lautenschläger, S., Lorenz, D., McIntosh, J., Neumann, C., Richter, H., et al. (2009) · Genetics · doi:10.1534/genetics.109.102186 · Cited by 136 · see citing works
Self-citationA TRADE-OFF FOR HOST PLANT UTILIZATION IN THE BLACK BEAN APHID,APHIS FABAE
Mackenzie, A. (1996) · Evolution · doi:10.1111/j.1558-5646.1996.tb04482.x · Cited by 130 · see citing works
Ji, H., Chu, S., Jiang, W., et al. (2006) · Genetics · doi:10.1534/genetics.105.054031 · Cited by 128 · see citing works
Pérez‐Vega, E., Pañeda, A., Rodríguez‐Suárez, C., et al. (2010) · Theoretical and Applied Genetics · doi:10.1007/s00122-010-1261-5 · Cited by 125 · see citing works
Burke, J. M., Gardner, K. A., & Rieseberg, L. H. (2002) · American Journal of Botany · doi:10.3732/ajb.89.9.1550 · Cited by 123 · see citing works
Feather pecking in chickens is genetically related to behavioural and developmental traits
Jensen, P., Keeling, L. J., Schütz, K. E., et al. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.06.029 · Cited by 115 · see citing works
Self-citationFry, J. D. (1993) · Evolution · doi:10.1111/j.1558-5646.1993.tb01224.x · Cited by 112 · see citing works
van Kaam, J. B. C. H. M., van Arendonk, J. A. M., Groenen, M. A. M., et al. (1998) · Livestock Production Science · doi:10.1016/s0301-6226(97)00171-1 · Cited by 106 · see citing works
Shared quantitative trait loci underlying the genetic correlation between continuous traits
Gardner, K. M., & Latta, R. G. (2007) · Molecular Ecology · doi:10.1111/j.1365-294x.2007.03499.x · Cited by 104 · see citing works
Calsbeek, R. G., & Smith, T. B. (2007) · Evolution · doi:10.1111/j.1558-5646.2007.00093.x · Cited by 96 · see citing works
Carlborg, Ö., Hocking, P. M., Burt, D. W., & Haley, C. (2004) · Genetics Research · doi:10.1017/s0016672304006779 · Cited by 95 · see citing works
Models to estimate maternal effects for juvenile body weight in broiler chickens
Koerhuis, A. N. M., & Thompson, R. (1997) · Genetics Selection Evolution · doi:10.1186/1297-9686-29-2-225 · Cited by 89 · see citing works
THE GENETIC ARCHITECTURE OF A FEMALE SEXUAL ORNAMENT
Wright, D., Kerje, S., Brändström, H., Schütz, K. E., Kindmark, A., Andersson, L., Jensen, P., & Pizzari, T. (2007) · Evolution · doi:10.1111/j.1558-5646.2007.00281.x · Cited by 85 · see citing works
Self-citationWei, M., & van der Werf, J. J. H. (1995) · Journal of Animal Science · doi:10.2527/1995.7382220x · Cited by 84 · see citing works
Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila
Curtsinger, J. W., & Khazaeli, A. A. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(01)00345-1 · Cited by 76 · see citing works
Leanness in domestic birds : genetic, metabolic and hormonal aspects
Leclercq, B., & Whitehead, C. C. (1988) · HAL (Le Centre pour la Communication Scientifique Directe) · Cited by 70 · see citing works
Buitenhuis, B., Rodenburg, T. B., Wissink, P., et al. (2004) · Poultry Science · doi:10.1093/ps/83.7.1077 · Cited by 66 · see citing works
Epistasis in Measured Genotypes: Drosophila P-Element Insertions
Clark, A. G., & Wang, L. (1997) · Genetics · doi:10.1093/genetics/147.1.157 · Cited by 64 · see citing works
Oka, H.-I. (1988) · Developments in crop science · doi:10.1016/b978-0-444-98919-2.50005-3 · Cited by 63 · see citing works
Genetic analysis of tonic immobility in young Japanese quail (Coturnix cotunix japonica)
BENOFF, F. H., & Siegel, P. B. (1976) · Animal Learning & Behavior · doi:10.3758/bf03214027 · Cited by 58 · see citing works
Wright, D., Kerje, S., Lundström, K., Babol, J., Schütz, K. E., Jensen, P., & Andersson, L. (2006) · Animal Genetics · doi:10.1111/j.1365-2052.2006.01515.x · Cited by 57 · see citing works
Self-citationEnvironment-Genetic Influences on Immunocompetence
Gross, W. B., & Siegel, P. B. (1988) · Journal of Animal Science · doi:10.2527/jas1988.6682091x · Cited by 52 · see citing works
Use of randomization testing to detect multiple epistatic QTLs
Carlborg, Ö., & Andersson, L. (2002) · Genetics Research · doi:10.1017/s001667230200558x · Cited by 51 · see citing works
Self-citationGriswold, C. K., & Whitlock, M. C. (2003) · Genetics · doi:10.1093/genetics/165.4.2181 · Cited by 50 · see citing works
Rubin, C., Brändström, H., Wright, D., et al. (2006) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.061203 · Cited by 49 · see citing works
Self-citationBidirectional selection for open-field activity in young chicks
Faure, J.-M. (1981) · Behavior Genetics · doi:10.1007/bf01065624 · Cited by 47 · see citing works
Realized Heritability of Tonic Immobility in White Leghorn Hens: A Replicated Single Generation Test
Campo, J. L., & Carnicer, C. (1993) · Poultry Science · doi:10.3382/ps.0722193 · Cited by 41 · see citing works
Epistatic regulation of behavioural and morphological traits in the zebrafish (Danio rerio)
Wright, D., Butlin, R. K., & Carlborg, Ö. (2006) · Behavior Genetics · doi:10.1007/s10519-006-9080-9 · Cited by 38 · see citing works
Self-citationGehad, A. E., Mashaly, M. M., Siegel, H. S., et al. (1999) · Veterinary Immunology and Immunopathology · doi:10.1016/s0165-2427(99)00008-2 · Cited by 36 · see citing works
Positive correlation between gene coexpression and positional clustering in the zebrafish genome
Ng, Y. K., Wu, W., & Zhang, L. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-42 · Cited by 30 · see citing works
Little epistasis for anxiety-related measures in the DeFries strains of laboratory mice
Flint, J., DeFries, J. C., & Henderson, N. D. (2004) · Mammalian Genome · doi:10.1007/s00335-003-3033-x · Cited by 24 · see citing works
Anthony, N. B., DUNNINGTON, E. A., & Siegel, P. B. (1989) · Poultry Science · doi:10.3382/ps.0680027 · Cited by 23 · see citing works
Väisänen, J., Lindqvist, C., & Jensen, P. (2004) · Livestock Production Science · doi:10.1016/j.livprodsci.2004.10.010 · Cited by 22 · see citing works
Self-citationGerken, M., & PETERSEN, J. (1992) · Poultry Science · doi:10.3382/ps.0710779 · Cited by 21 · see citing works
Genetic Assessment of the Behavior of White Leghorn Type Pullets in an Open Field
WEBSTER, A. B., & Hurnik, J. F. (1989) · Poultry Science · doi:10.3382/ps.0680335 · Cited by 17 · see citing works
Organization of Human Cardiovascular-expressed Genes on Chromosomes 21 and 22
Dempsey, A. A., Pabalan, N., Tang, H.-C., et al. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2000.1335 · Cited by 17 · see citing works
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Genetical genomics of behavior: a novel chicken genomic model for anxiety behavior
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Self-citationGenomic Analyses Unveil Helmeted Guinea Fowl (<i>Numida meleagris</i>) Domestication in West Africa
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- Authors
- WRIGHT, D., RUBIN, C. ‐., MARTINEZ BARRIO, A., SCHÜTZ, K., KERJE, S., BRÄNDSTRÖM, H., KINDMARK, A., JENSEN, P., & ANDERSSON, L.
- Affiliations
- Linköping University (SE)
- Uppsala University (SE)
- Swedish University of Agricultural Sciences (SE)
- Uppsala University Hospital (SE)
- Corresponding author
- WRIGHT, D.
- Venue
- Molecular Ecology
- Publisher
- Wiley
- Published
- 2010-10-29
- Volume
- 19
- Issue
- 23
- Pages
- 5140-5156
- ISSN
- 0962-1083 (ISSN-L)
- 1365-294X
- OpenAlex
- W2135126969
- Cited by
- 76
- References
- 97
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 4 · 2023: 3 · 2022: 6 · 2021: 3 · 2020: 2 · 2019: 5 · 2018: 10 · 2017: 4 · 2016: 2 · 2015: 9 · 2014: 3 · 2013: 8 · 2012: 6
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Ecology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Svenska Forskningsrådet Formas
- Sveriges Lantbruksuniversitet
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
- Keywords
- chicken domestication, pleiotropy, epistasis, quantitative trait loci, linkage, antagonistic pleiotropy, genetic architecture, F2 intercross, life-history traits, morphological characters, behavioral characteristics, genetic correlation
- MeSH terms
- Animals, Chickens, Crosses, Genetic, Epistasis, Genetic, Genotype, Genetic Linkage, Sequence Analysis, DNA, Microsatellite Repeats, Evolution, Molecular, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Genetic Pleiotropy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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