The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A multifaceted role for polyamines in bacterial pathogens
Abstract
Summary: Polyamines are polycationic molecules with a hydrocarbon backbone and multiple amino groups. Descriptions of the physiological roles of polyamines have often been limited to their interaction with negatively charged nucleic acids. Of late, reports linking polyamines to microbial carcinogenesis, biofilm formation, escape from phagolysosomes, bacteriocin production, toxin activity and protection from oxidative and acid stress have been published, providing insights about their other important but lesser known functions. This review focuses on recently discovered novel functions of polyamines in microorganisms, with an emphasis on bacterial pathogens of humans.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
McClelland, M., Sanderson, K. E., Clifton, S. W., Latreille, P., Porwollik, S., Sabo, A., Meyer, R., Bieri, T., Ozersky, P., McLellan, M., et al. (2004) · Nature Genetics · doi:10.1038/ng1470 · Cited by 391
Spermine inhibition of monocyte activation and inflammation
Zhang, M., Borovikova, L. V., Wang, H., Metz, C., & Tracey, K. J. (1999) · Molecular Medicine · doi:10.1007/bf03402072 · Cited by 92 · cited 1×
“However, it is important to note that, under most circumstances, spermine inhibits pro-inflammatory cytokines in human mononuclear cells in response to LPS stimulation (Zhang et al., 1999).”
Background
Cited by
Pipkins, H. R., Bradshaw, J. L., Keller, L. E., Swiatlo, E., & McDaniel, L. S. (2017) · PLOS ONE · doi:10.1371/journal.pone.0179159 · Cited by 1,338
“The pot operon and the transport of polyamines also appears to be necessary for regulation of certain encapsulated pneumococcal virulence factors, such as pneumolysin and capsule [17,18].”
BackgroundSelf-citationGut mucosal microbiome across stages of colorectal carcinogenesis
Nakatsu, G., Li, X., Zhou, H., Sheng, J., Wong, S. H., Wu, W. K. K., Ng, S. C., Tsoi, H., Dong, Y., Zhang, N., et al. (2015) · Nature Communications · doi:10.1038/ncomms9727 · Cited by 701
Remaining mysteries of molecular biology: the role of polyamines in the cell
Miller-Fleming, L., Olin-Sandoval, V., Campbell, K., & Ralser, M. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.06.020 · Cited by 658
Intestinal luminal nitrogen metabolism: Role of the gut microbiota and consequences for the host
Davila, A.-M., Blachier, F., Gotteland, M., Andriamihaja, M., Benetti, P.-H., Sanz, Y., & Tomé, D. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2012.11.005 · Cited by 548
Microbial Fermentation of Dietary Protein: An Important Factor in Diet–Microbe–Host Interaction
Diether, N. E., & Willing, B. P. (2019) · Microorganisms · doi:10.3390/microorganisms7010019 · Cited by 554
Metadata
- Authors
- Shah, P., & Swiatlo, E.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2008-03-05
- Volume
- 68
- Issue
- 1
- Pages
- 4-16
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2156328657
- Cited by
- 424
- References
- 2
- FWCI
- 4.71
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A multifaceted role for polyamines in bacterial pathogens. https://app.cochat.ai/papers/10.1111/j.1365-2958.2008.06126.x
- The paper
- Shah, P., & Swiatlo, E. (2008). A multifaceted role for polyamines in bacterial pathogens. Molecular Microbiology. https://doi.org/10.1111/j.1365-2958.2008.06126.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
