The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Risk factors for chronic constipation and a possible role of analgesics
Abstract
Abstract Constipation has an estimated prevalence of 15% in the general population. However, the etiopathogenesis of this condition remains relatively obscure. This study sought to identify potentially novel risk factors for chronic constipation. A valid self‐report questionnaire was mailed to an age‐ and gender‐stratified random sample of Olmsted County, Minnesota residents aged 30–64 years. A logistic regression model that adjusted for age, gender and somatic symptom score (SSC) was used to identify factors associated with chronic constipation. People reporting symptoms of irritable bowel syndrome (IBS) were excluded. Of the 892 eligible subjects, 653 (73%) returned the survey. Among the 523 subjects not reporting IBS symptoms, chronic constipation was reported by 93 (18%) of the respondents. Chronic constipation was significantly associated with use of acetaminophen [≥7 tablets per week, OR = 2.7 (1.1–6.6)]; aspirin [OR = 1.7 (1.0–2.7)]; non‐steroidal anti‐inflammatory drugs [OR = 1.8 (1.1–3.0)]; and SSC. No association was detected for age, gender, body mass index, marital status, smoking, alcohol, coffee, education level, food allergy, exposure to pets, stress, emotional support, or water supply. Chronic constipation is associated with use of acetaminophen, aspirin and non‐steroidal anti‐inflammatory drugs. The explanation of these associations requires further investigation.
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“Coffee consumption is not associated with chronic constipation [111] but rather inversely associated with chronic constipation [112].”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [111]
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Cites
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History of the Rochester Epidemiology Project
Melton, L. J. (1996) · Mayo Clinic Proceedings · doi:10.4065/71.3.266 · Cited by 1,443
Talley, N. J., Zinsmeister, A. R., & Melton, L. J. (1995) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117548 · Cited by 327
Self-citation
Research works printed but not linked: 23
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Cited by
Lacy, B. E., Mearin, F., Chang, L., Chey, W. D., Lembo, A. J., Simren, M., & Spiller, R. (2016) · Gastroenterology · doi:10.1053/j.gastro.2016.02.031 · Cited by 2,866
Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update
Nehlig, A. (2022) · Nutrients · doi:10.3390/nu14020399 · Cited by 158
Preventing constipation: a review of the laxative potential of food ingredients
Gélinas, P. (2013) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2012.03207.x · Cited by 26
Metadata
- Authors
- Chang, J. Y., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., & Talley, N. J.
- Venue
- Neurogastroenterology & Motility
- Publisher
- Wiley
- Published
- 2007-11
- Volume
- 19
- Issue
- 11
- Pages
- 905-911
- ISSN
- 1350-1925
- 1365-2982
- Cited by
- 61
- References
- 3
- Language
- en
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.