The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Quality control for plant metabolomics: reporting MSI‐compliant studies
Open accessAbstract
Summary: The Metabolomics Standards Initiative (MSI) has recently released documents describing minimum parameters for reporting metabolomics experiments, in order to validate metabolomic studies and to facilitate data exchange. The reporting parameters encompassed by MSI include the biological study design, sample preparation, data acquisition, data processing, data analysis and interpretation relative to the biological hypotheses being evaluated. Herein we exemplify how such metadata can be reported by using a small case study – the metabolite profiling by GC‐TOF mass spectrometry of Arabidopsis thaliana leaves from a knockout allele of the gene At1g08510 in the Wassilewskija ecotype. Pitfalls in quality control are highlighted that can invalidate results even if MSI reporting standards are fulfilled, including reliable compound identification and integration of unknown metabolites. Standardized data processing methods are proposed for consistent data storage and dissemination via databases.
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Self-citationSmith, C. A., Want, E. J., O'Maille, G., Abagyan, R., & Siuzdak, G. (2006) · Analytical Chemistry · doi:10.1021/ac051437y · Cited by 5,262
Metabolomics—the link between genotypes and phenotypes
Fiehn, O. (2002) · Plant Molecular Biology · doi:10.1023/a:1013713905833 · Cited by 3,445
Self-citationMetabolomics — the link between genotypes and phenotypes
Fiehn, O. (2002) · Functional Genomics · doi:10.1007/978-94-010-0448-0_11 · Cited by 3,167
Self-citationRanade, V. V. (2009) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e31817c941f · Cited by 2,775
Gas chromatography mass spectrometry–based metabolite profiling in plants
Lisec, J., Schauer, N., Kopka, J., Willmitzer, L., & Fernie, A. R. (2006) · Nature Protocols · doi:10.1038/nprot.2006.59 · Cited by 2,170
Metabolite profiling for plant functional genomics
Fiehn, O., Kopka, J., Dörmann, P., Altmann, T., Trethewey, R. N., & Willmitzer, L. (2000) · Nature Biotechnology · doi:10.1038/81137 · Cited by 2,127
Self-citationRoessner, U., Luedemann, A., Brust, D., Fiehn, O., Linke, T., Willmitzer, L., & Fernie, A. R. (2001) · The Plant Cell · doi:10.1105/tpc.13.1.11 · Cited by 1,017
Self-citationRhee, S. Y. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg076 · Cited by 920
MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data
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Fiehn, O. (2016) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb3004s114 · Cited by 917
Self-citationSegal, L. N., Clemente, J. C., Tsay, J.-C. J., Koralov, S. B., Keller, B. C., Wu, B. G., Li, Y., Shen, N., Ghedin, E., Morris, A., et al. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.31 · Cited by 685
Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling
Zheng, H., Powell, J. E., Steele, M. I., Dietrich, C., & Moran, N. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701819114 · Cited by 664
Badri, D. V., Chaparro, J. M., Zhang, R., Shen, Q., & Vivanco, J. M. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.433300 · Cited by 578
Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics
Lai, Z., Tsugawa, H., Wohlgemuth, G., Mehta, S., Mueller, M., Zheng, Y., Ogiwara, A., Meissen, J., Showalter, M., Takeuchi, K., et al. (2018) · Nature Methods · doi:10.1038/nmeth.4512 · Cited by 560
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Metadata
- Authors
- Fiehn, O., Wohlgemuth, G., Scholz, M., Kind, T., Lee, D. Y., Lu, Y., Moon, S., & Nikolau, B.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2008-02
- Volume
- 53
- Issue
- 4
- Pages
- 691-704
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W1597941165
- Cited by
- 675
- References
- 33
- FWCI
- 9.80
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Fiehn, O., Wohlgemuth, G., Scholz, M., Kind, T., Lee, D. Y., Lu, Y., Moon, S., & Nikolau, B. (2008). Quality control for plant metabolomics: reporting MSI‐compliant studies. The Plant Journal. https://doi.org/10.1111/j.1365-313x.2007.03387.x
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