The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
A review of applications of tea tree oil in dermatology
Abstract
Tea tree oil (TTO) is an essential oil, steam‐distilled from the Australian native plant, Melaleuca alternifolia. It has a minimum content of terpinen‐4‐ol and a maximum content of 1, 8‐cineole. Terpinen‐4‐ol is a major TTO component which exhibits strong antimicrobial and anti‐inflammatory properties. Tea tree oil exerts antioxidant activity and has been reported to have broad‐spectrum antimicrobial activity against bacterial, viral, fungal, and protozoal infections affecting skin and mucosa. Several studies have suggested the uses of TTO for the treatment of acne vulgaris, seborrheic dermatitis, and chronic gingivitis. It also accelerates the wound healing process and exhibits anti‐skin cancer activity. This review opens up new horizons for dermatologists in the use of this herbal agent.
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In the citing paper
“Alternative therapies have been reported as well, such as tea tree oil [40,41].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [40]
In the citing paper
“According to the Oxford evidence hierarchy, this would fall under the category of Level IV evidence. Additionally, the paper could benefit from a more critical analysis of the potential risks and side effects associated with the use of tea tree oil in dermatology.”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [14]
Citations
Cites
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Italian Journal of Public Health · doi:10.2427/5768 · Cited by 3,374
Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties
Carson, C. F., Hammer, K. A., & Riley, T. V. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.1.50-62.2006 · Cited by 1,429
A review of the toxicity of Melaleuca alternifolia (tea tree) oil
Hammer, K. A., Carson, C. F., Riley, T. V., et al. (2005) · Food and Chemical Toxicology · doi:10.1016/j.fct.2005.09.001 · Cited by 313
A comparative study of tea‐tree oil versus benzoylperoxide in the treatment of acne
Bassett, I. B., Barnetson, R. S. C., & Pannowitz, D. L. (1990) · Medical Journal of Australia · doi:10.5694/j.1326-5377.1990.tb126150.x · Cited by 286
Teissèdre, P., & Waterhouse, A. L. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990921x · Cited by 249
Schnitzler, P., Schön, K., & Reichling, J. (2001) · PubMed · Cited by 233
Herbal medicines for treatment of bacterial infections: a review of controlled clinical trials
Martin, K. W. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg087 · Cited by 226
Hammer, K., Carson, C., & Riley, T. (1998) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/42.5.591 · Cited by 223
Mondello, F., Bernardis, F. D., Girolamo, A., et al. (2006) · BMC Infectious Diseases · doi:10.1186/1471-2334-6-158 · Cited by 222
In vitro and in vivo killing of ocular Demodex by tea tree oil
Gao, Y.-Y. (2005) · British Journal of Ophthalmology · doi:10.1136/bjo.2005.072363 · Cited by 212
Cited by
Sorted by citations
Essential oils used in aromatherapy: A systemic review
Ali, B., Al‐Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/j.apjtb.2015.05.007 · Cited by 1,184
“Cold, fever, flu and chickenpox have called for its use [71,72].”
BackgroundBeneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases
Forni, C., Facchiano, F., Bartoli, M., Pieretti, S., Facchiano, A., D’Arcangelo, D., Norelli, S., Valle, G., Nisini, R., Beninati, S., et al. (2019) · BioMed Research International · doi:10.1155/2019/8748253 · Cited by 546
“The essential oil from Melaleuca alternifolia also shows antioxidant activities potentially useful in dermatitis and skin cancers [160].”
BackgroundPlant-Derived Antioxidants: Significance in Skin Health and the Ageing Process
Michalak, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020585 · Cited by 460
Seborrheic Dermatitis and Dandruff: A Comprehensive Review
(2015) · Journal of Clinical and Investigative Dermatology · doi:10.13188/2373-1044.1000019 · Cited by 398
“Alternative therapies have been reported as well, such as tea tree oil [40,41].”
Skin Wound Healing and Phytomedicine: A Review
Pazyar, N., Yaghoobi, R., Rafiee, E., Mehrabian, A., & Feily, A. (2014) · Skin Pharmacology and Physiology · doi:10.1159/000357477 · Cited by 278
Self-citation
Metadata
- Authors
- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A.
- Affiliations
- Ahvaz Jundishapur University of Medical Sciences (IR)
- Corresponding author
- Pazyar, Nader
- Venue
- International Journal of Dermatology
- Publisher
- Wiley
- Published
- 2012-09-24
- Volume
- 52
- Issue
- 7
- Pages
- 784-790
- ISSN
- 0011-9059 (ISSN-L)
- 1365-4632
- OpenAlex
- W2016711385
- Semantic Scholar
- 8af9fc3638195427a56def3e97838ca793b73aea
- Cited by
- 252
- References
- 46
- Citations by year
- 2026: 14 · 2025: 23 · 2024: 23 · 2023: 32 · 2022: 37 · 2021: 31 · 2020: 23 · 2019: 15 · 2018: 9 · 2017: 14 · 2016: 8 · 2015: 12 · 2014: 7 · 2013: 4
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- tea tree oil, Melaleuca alternifolia, terpinen-4-ol, 1,8-cineole, antimicrobial activity, anti-inflammatory activity, antioxidant activity, acne, seborrheic dermatitis, chronic gingivitis, wound healing, anticancer activity, herbal medicine, skin infections
- MeSH terms
- Anti-Infective Agents, Local, Humans, Skin Diseases, Tea Tree Oil
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