Position Paper: Allergen standardization and skin tests
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Patients are typically diagnosed as sensitized based on a positive skin prick test, usually at least 3 mm wheal diameter, or a positive specific serum IgE, usually at least 0.35 kU/L.
“In epidemiology and clinical practice, patients are typically diagnosed as being “sensitized” based on a positive SPT (usually ≥3 mm wheal diameter), or a positive specific serum IgE (usually ≥0.35 kU/L [specific IgEs are reported in arbitrary units, thus the unit kU]).1007,1008”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [1007]
The Introduction (page not available in our copy) calls skin prick testing the method of choice for routine diagnosis, and §1.1 links positive allergen skin tests to IgE-mediated responses. The passages do not give a ≥3 mm wheal cutoff or address a ≥0.35 kU/L serum-specific IgE cutoff; searches for both numbers and test-interpretation criteria found no such passage. (LLM, conf=0.85)
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- Authors
- Dreborg, S., & Frew, A.
- ORCID
- Venue
- Allergy
- Publisher
- Wiley
- Published
- 1993-02
- Volume
- 48
- Issue
- s14
- Pages
- 49-54
- ISSN
- 0105-4538 (ISSN-L)
- 1398-9995
- OpenAlex
- W2026254290
- Cited by
- 753
- References
- 29
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 7 · 2021: 10 · 2020: 14 · 2019: 18 · 2018: 10 · 2017: 18 · 2016: 21 · 2015: 26 · 2014: 35 · 2013: 40 · 2012: 46
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Allergy (publishedVersion)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Keywords
- allergen standardization, skin testing, allergen extracts, allergen nomenclature, allergen potency
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