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Cited by 308Multiple Sclerosis Research StudiesGenetic Associations and EpidemiologySystemic Lupus Erythematosus Research

Multiple Sclerosis: Association with HL—A3

NAITO, S., NAMEROW, N., MICKEY, M. R., TERASAKI, P. I.·1972·Tissue Antigens
DOI 10.1111/j.1399-0039.1972.tb00111.x
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Abstract

The incidence of HL—A3 among 94 patients with a diagnosis of multiple sclerosis (MS) was significantly higher than for 871 normal persons. In addition, some increase in Te58 and decrease in HL—A2 and Te60 frequencies was noted. The well‐known higher incidence of MS among Caucasians than among Orientals is paralleled by the higher incidence of HL—A3 and Te58 among Caucasians and a lower incidence of Te60.

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Crossref · 10.1111/j.1399-0039.1972.tb00111.x

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  • The first genetic risk factors discovered for multiple sclerosis were three serological alleles of the human leucocyte antigens encoded in the major histocompatibility complex.

    “three serological alleles of the human leucocyte antigens (HLA), encoded in the major histocompatibility complex8, 9, 10, 11 (MHC, chromosome 6p21).”

    From Genome‐wide association studies of multiple sclerosis (2018) · cites this paper as [8]

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Authors
NAITO, S., NAMEROW, N., MICKEY, M. R., & TERASAKI, P. I.
Affiliations
University of California, Los Angeles (US)
Corresponding author
NAITO, S.
Venue
Tissue Antigens
Publisher
Wiley
Published
1972-01
Volume
2
Issue
1
Pages
1-4
ISSN
  • 0001-2815 (ISSN-L)
  • 1399-0039
DOI
10.1111/j.1399-0039.1972.tb00111.x
OpenAlex
W1970835952
Cited by
308
References
0
Citations by year
2026: 2 · 2025: 2 · 2024: 8 · 2023: 2 · 2022: 8 · 2021: 4 · 2020: 6 · 2019: 12 · 2018: 8 · 2017: 7 · 2016: 6 · 2015: 10 · 2014: 12 · 2013: 10 · 2012: 10
FWCI
24.76
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 13431 d)
Locations
  • Tissue Antigens (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
  • Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
Keywords
multiple sclerosis, HLA-A3, HLA-A2, HLA-B*58, HLA-B60, HLA antigens, genetic association, racial differences, Caucasians, Oriental
MeSH terms
Cytotoxicity Tests, Immunologic, Gene Frequency, Histocompatibility Antigens, Humans, Multiple Sclerosis, White People

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