The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Evolution of cognitive impairment in bipolar disorder: a systematic review of cross‐sectional evidence
Abstract
Objectives: The notion that sufferers of bipolar disorder achieve complete syndromal and functional recovery between illness episodes has been brought into question by evidence that a large proportion of patients fail to regain premorbid levels of functioning after the resolution of major affective symptoms. A growing body of evidence suggests that bipolar patients exhibit neuropsychological impairment that persists even during the euthymic state, which may be a contributory factor to poor psychosocial outcome. However, the aetiology of such impairment and its relation to progression of illness are not well understood. This review aims to consider evidence from studies investigating both the relationship between cognitive impairment and clinical outcome and studies of neurocognitive function in unaffected first‐degree relatives (FDRs) of bipolar sufferers to address issues of the temporal evolution of cognitive impairment in bipolar disorder. Methods: Systematic literature review. Results: The weight of evidence suggests that greater neuropsychological dysfunction in bipolar disorder is associated with a worse prior course of illness, particularly the number of manic episodes, hospitalizations and length of illness. The most consistent finding was a negative relationship between the number of manic episodes and verbal declarative memory performance. Impairment in unaffected FDRs was reported in verbal declarative memory and some facets of executive function. Conclusions: Cognitive impairment may be a trait vulnerability factor for bipolar disorder that is present before illness onset and worsens as the illness progresses. Further investigation into the causal relationship between cognitive impairment and illness course is essential.
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Cites
Subgenual prefrontal cortex abnormalities in mood disorders
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Sustained attention deficit in bipolar disorder
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Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder
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Self-citationYoung, A. H., Gallagher, P., Watson, S., Del-Estal, D., Owen, B. M., & Nicol Ferrier, I. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300471 · Cited by 318
Decision-making cognition in mania and depression
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Subgenual Cingulate Cortex Volume in First-Episode Psychosis
Hirayasu, Y., Shenton, M. E., Salisbury, D. F., Kwon, J. S., Wible, C. G., Fischer, I. A., Yurgelun-Todd, D., Zarate, C., Kikinis, R., Jolesz, F. A., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.7.1091 · Cited by 301
A Preliminary fMRI Study of Sustained Attention in Euthymic, Unmedicated Bipolar Disorder
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Neuropsychological performance of monozygotic twins discordant for bipolar disorder
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Cited by
Berk, M., Kapczinski, F., Andreazza, A. C., Dean, O. M., Giorlando, F., Maes, M., Yücel, M., Gama, C. S., Dodd, S., Dean, B., et al. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.001 · Cited by 1,178
A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder
Robinson, L. J., Thompson, J. M., Gallagher, P., Goswami, U., Young, A. H., Ferrier, I. N., & Moore, P. B. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.02.016 · Cited by 962
Self-citationNeurocognitive impairment in bipolar disorder patients: functional implications
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The assessment of neuropsychological functioning in schizophrenia
Reichenberg, A. (. (2010) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2010.12.3/areichenberg · Cited by 271
Clinical implications of a staging model for bipolar disorders
Kapczinski, F., Dias, V. V., Kauer-Sant’Anna, M., Frey, B. N., Grassi-Oliveira, R., Colom, F., & Berk, M. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.31 · Cited by 263
Metadata
- Authors
- Robinson, L. J., & Nicol Ferrier, I.
- Venue
- Bipolar Disorders
- Publisher
- Wiley
- Published
- 2006-03-15
- Volume
- 8
- Issue
- 2
- Pages
- 103-116
- ISSN
- 1398-5647 (ISSN-L)
- 1399-5618
- OpenAlex
- W2029064583
- Cited by
- 531
- References
- 10
- FWCI
- 4.47
- Type
- journal article
- Language
- en
- Open access
- closed
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