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Cited by 274

The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.

Neurocognitive impairment in bipolar disorder patients: functional implications

Open access
Wingo, Aliza P, Harvey, Philip D, Baldessarini, Ross J·2009·Bipolar Disorders
DOI 10.1111/j.1399-5618.2009.00665.x
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Abstract

Background: Functional recovery among treated bipolar disorder (BPD) patients is far less likely than syndromal and even symptomatic recovery. We hypothesized that increasingly well‐documented aspects of cognitive impairment may contribute to poor functional outcomes in BPD patients, and reviewed the available research on the topic. Methods: Computerized literature searching identified 12 studies with 13 comparisons that simultaneously evaluated cognitive and functional status in euthymic (n = 8) or non‐euthymic (n = 5 comparisons) adult BPD patients versus otherwise similar healthy controls. Results: In 6/8 studies of euthymic BPD patients and 5/5 studies of non‐euthymic BPD patients, neurocognitive impairment was significantly associated with impaired psychosocial functioning, even after adjusting for residual mood symptoms and relevant demographic and clinical variables. Cognitive status was consistently assessed with standardized, performance‐based neuropsychological tests, but functional status usually was based on subjective self‐appraisals. Approximately 55% of BPD patients were unemployed. Conclusions: Available studies are limited by subjective assessments of functional status rather than objective, performance‐based measures. Nevertheless, they support the hypothesis that enduring aspects of cognitive impairment found even in euthymic BPD patients are associated with inferior functioning. These findings encourage further studies with better assessment methods and greater rehabilitative efforts in BPD patients.

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Metadata

Authors
Wingo, A. P., Harvey, P. D., & Baldessarini, R. J.
Venue
Bipolar Disorders
Publisher
Wiley
Published
2009-02-25
Volume
11
Issue
2
Pages
113-125
ISSN
  • 1398-5647 (ISSN-L)
  • 1399-5618
DOI
10.1111/j.1399-5618.2009.00665.x
OpenAlex
W1980163556
Cited by
274
References
83
FWCI
13.84
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Neurocognitive impairment in bipolar disorder patients: functional implications. https://app.cochat.ai/papers/10.1111/j.1399-5618.2009.00665.x
The paper
Wingo, A. P., Harvey, P. D., & Baldessarini, R. J. (2009). Neurocognitive impairment in bipolar disorder patients: functional implications. Bipolar Disorders. https://doi.org/10.1111/j.1399-5618.2009.00665.x

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.