Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors

Alternative activation of macrophages: mechanism and functions

Gordon, S., & Martinez, F. O. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.007 · Cited by 4,197 · see citing works

Transduction of psychosocial stress into the neurobiology of recurrent affective disorder

(1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.8.999 · Cited by 1,848 · see citing works

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

Tsankova, N. M., Berton, O., Renthal, W., Kumar, A., Neve, R. L., & Nestler, E. J. (2006) · Nature Neuroscience · doi:10.1038/nn1659 · Cited by 1,780 · see citing works

Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders

MCEWEN, B. S. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1314.001 · Cited by 1,638 · see citing works

Manic-Depressive Insanity and Paranoia.

(1921) · JAMA · doi:10.1001/jama.1921.02630330070026 · Cited by 1,612 · see citing works

Glutamate neurotoxicity in cortical cell culture

Choi, D. W., Maulucci-Gedde, M., & Kriegstein, A. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-02-00357.1987 · Cited by 1,506 · see citing works

Manic Depressive Insanity and Paranoia

Kraepelin, E. (1921) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-192104000-00057 · Cited by 1,327 · see citing works

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

Schwarcz, R. M., Whetsell, W. O., & Mangano, R. M. (1983) · Science · doi:10.1126/science.6849138 · Cited by 1,269 · see citing works

New insights into BDNF function in depression and anxiety

Martinowich, K., Manji, H., & Lu, B. (2007) · Nature Neuroscience · doi:10.1038/nn1971 · Cited by 1,221 · see citing works

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

Ng, F., Berk, M., Dean, O., & Bush, A. I. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707008401 · Cited by 1,069 · see citing works

Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial

Tyring, S., Gottlieb, A., Papp, K., Gordon, K., Leonardi, C., Wang, A., Lalla, D., Woolley, M., Jahreis, A., Zitnik, R., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(05)67763-x · Cited by 1,069 · see citing works

Cognitive endophenotypes of bipolar disorder: A meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives

Bora, E., Yücel, M., & Pantelis, C. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.06.009 · Cited by 1,021 · see citing works

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

Diazgranados, N., Ibrahim, L., Brutsche, N. E., Newberg, A., Kronstein, P., Khalife, S., Kammerer, W. A., Quezado, Z., Luckenbaugh, D. A., Salvadore, G., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.90 · Cited by 963 · see citing works

Autoxidation versus Covalent Binding of Quinones as the Mechanism of Toxicity of Dopamine, 6-Hydroxydopamine, and Related Compounds toward C1300 Neuroblastoma Cells in Vitro

Graham, D. G., Tiffany, S. M., BELL, W. R., & Gutknecht, W. F. (1978) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13536-0 · Cited by 953 · see citing works

Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions

McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01860.x · Cited by 919 · see citing works

Long-Chain ω-3 Fatty Acids for Indicated Prevention of Psychotic Disorders: A Randomized, Placebo-Controlled Trial

Amminger, G. P., Schäfer, M. R., Papageorgiou, K., Klier, C. M., Cotton, S. M., Harrigan, S. M., Mackinnon, A., McGorry, P. D., & Berger, G. E. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.192 · Cited by 896 · see citing works

Association of Western and Traditional Diets With Depression and Anxiety in Women

Jacka, F. N., Pasco, J. A., Mykletun, A., Williams, L. J., Hodge, A. M., O'Reilly, S. L., Nicholson, G. C., Kotowicz, M. A., & Berk, M. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09060881 · Cited by 812 · see citing works

Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS

Stone, T. W., & Perkins, M. N. (1981) · European Journal of Pharmacology · doi:10.1016/0014-2999(81)90587-2 · Cited by 751 · see citing works

Cytokine Production and Treatment Response in Major Depressive Disorder

Lanquillon, S. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00134-7 · Cited by 735 · see citing works

The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

Müller, N., & Schwarz, M. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002006 · Cited by 670 · see citing works

Dopamine Oxidation Alters Mitochondrial Respiration and Induces Permeability Transition in Brain Mitochondria

Berman, S. B., & Hastings, T. G. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0731127.x · Cited by 664 · see citing works

Lithium-induced increase in human brain grey matter

Moore, G. J., Bebchuk, J. M., Wilds, I. B., Chen, G., & Menji, H. K. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02793-8 · Cited by 649 · see citing works

Cerebral Metabolic Rates for Glucose in Mood Disorders

Baxter, L. R. (1985) · Archives of General Psychiatry · doi:10.1001/archpsyc.1985.01790280019002 · Cited by 602 · see citing works

Functional outcome in bipolar disorder: the role of clinical and cognitive factors

Martínez‐Arán, A., Vieta, E., Torrent, C., Sánchez‐Moreno, J., Goikolea, J. M., Salamero, M., Malhi, G. S., González-Pinto, A. M., Daban, C., Alvarez-Grandi, S. A., et al. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00327.x · Cited by 586 · see citing works

Cognitive–behavioural therapy for severe and recurrent bipolar disorders: Randomised controlled trial

Scott, J., Paykel, E., Morriss, R., Bentall, R., Kinderman, P., Johnson, T., Abbott, R., & Hayhurst, H. (2006) · British Journal of Psychiatry · doi:10.1192/bjp.188.4.313 · Cited by 566 · see citing works

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

Krystal, J. H., Sanacora, G., Blumberg, H., Anand, A., Charney, D. S., Marek, G., Epperson, C. N., Goddard, A., & Mason, G. F. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001021 · Cited by 553 · see citing works

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

Chalecka-Franaszek, E., & Chuang, D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.15.8745 · Cited by 544 · see citing works

Evolution of cognitive impairment in bipolar disorder: a systematic review of cross‐sectional evidence

Robinson, L. J., & Ferrier, I. N. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00277.x · Cited by 533 · see citing works

Inflammation and the Phenomenology, Pathophysiology, Comorbidity, and Treatment of Bipolar Disorder

Goldstein, B. I., Kemp, D. E., Soczynska, J. K., & McIntyre, R. S. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08r04505 · Cited by 510 · see citing works

N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial

Berk, M., Copolov, D. L., Dean, O., Lu, K., Jeavons, S., Schapkaitz, I., Anderson-Hunt, M., & Bush, A. I. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.022 · Cited by 500 · see citing works

Molecular Evidence for Mitochondrial Dysfunction in Bipolar Disorder

Konradi, C. L., Eaton, M. E., MacDonald, M. L., Walsh, J. P., Benes, F. M., & Heckers, S. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.3.300 · Cited by 499 · see citing works

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis

Iwamoto, K., Bundo, M., & Kato, T. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddi022 · Cited by 496 · see citing works

Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood Disorders

Yüksel, Ç., & Öngür, D. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.016 · Cited by 493 · see citing works

Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes

Green, K., Brand, M. D., & Murphy, M. P. (2004) · Diabetes · doi:10.2337/diabetes.53.2007.s110 · Cited by 490 · see citing works

Allostatic load in bipolar disorder: Implications for pathophysiology and treatment

Kapczinski, F. P., Vieta, E., Andreazza, A. C., Frey, B. N., Gomes, F. A., Tramontina, J., Kauer‐Sant’Anna, M., Grassi‐Oliveira, R., & Post, R. M. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.10.005 · Cited by 479 · see citing works

Depression, stress and immunological activation: The role of cytokines in depressive disorders

Connor, T. J., & Leonard, B. E. (1998) · Life Sciences · doi:10.1016/s0024-3205(97)00990-9 · Cited by 478 · see citing works

Suicide and Attempted Suicide in Bipolar Disorder: A Systematic Review of Risk Factors

Hawton, K., Sutton, L., Haw, C., Sinclair, J., & Harriss, L. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0604 · Cited by 467 · see citing works

The Mood‐Stabilizing Agent Valproate Inhibits the Activity of Glycogen Synthase Kinase‐3

Chen, G., Huang, L., Jiang, Y., & Manji, H. K. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0721327.x · Cited by 439 · see citing works

CREB DNA binding activity is inhibited by glycogen synthase kinase‐3β and facilitated by lithium

Grimes, C. A., & Jope, R. S. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00495.x · Cited by 437 · see citing works

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

Foster, A. C., Vezzani, A., French, E. D., & Schwarcz, R. M. (1984) · Neuroscience Letters · doi:10.1016/0304-3940(84)90050-8 · Cited by 435 · see citing works

Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder

Kauer‐Sant’Anna, M., Kapczinski, F. P., Andreazza, A. C., Bond, D. J., Lam, R. W. M., Young, L. T., & Yatham, L. N. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145708009310 · Cited by 434 · see citing works

Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients

Rao, J. S., Harry, G. J., Rapoport, S. I., & Kim, H. W. (2010) · Molecular Psychiatry · doi:10.1038/mp.2009.47 · Cited by 432 · see citing works

Role of Leptin in the Activation of Immune Cells

Riejos, P. F., Najib, S., Santos‐Álvarez, J., Martín-Romero, C., Pérez‐Pérez, A., González-Yanes, C., & Sánchez‐Margalet, V. (2010) · Mediators of Inflammation · doi:10.1155/2010/568343 · Cited by 432 · see citing works

Comparison of cytokine levels in depressed, manic and euthymic patients with bipolar disorder

Brietzke, E., Stertz, L., Fernandes, B. S., Kauer-Sant’Anna, M., Mascarenhas, M., Escosteguy Vargas, A., Chies, J. A., & Kapczinski, F. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.12.001 · Cited by 423 · see citing works

<i>N</i> -acetylcysteine for antioxidant therapy: pharmacology and clinical utility

Dodd, S., Dean, O., Copolov, D. L., Malhi, G. S., & Berk, M. (2008) · Expert Opinion on Biological Therapy · doi:10.1517/14728220802517901 · Cited by 413 · see citing works

Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2’s neurotrophic effects?

Moore, G. J., Bebchuk, J. M., Hasanat, K., Chen, G., Seraji‐Bozorgzad, N., Wilds, I. B., Faulk, M. W., Koch, S., Glitz, D. A., Jolkovsky, L., et al. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00252-3 · Cited by 401 · see citing works

Dopamine dysregulation syndrome: implications for a dopamine hypothesis of bipolar disorder

Berk, M., Dodd, S., Kauer‐Sant’Anna, M., Malhi, G. S., Bourin, M., Kapczinski, F., & Norman, T. (2007) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.01058.x · Cited by 396 · see citing works

The longitudinal course of recurrent affective illness: Life chart data from research patients at the NIMH

Roy‐Byrne, P., Post, R. M., Uhde, T. W., Porcu, T., & Davis, D. (1985) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1985.tb10510.x · Cited by 391 · see citing works

Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes

Cunha, A. B. M., Frey, B. N., Andreazza, A. C., Goi, J. D., Rosa, A. R., Gonçalves, C. A., Santin, A. M. P., & Kapczinski, F. P. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.12.085 · Cited by 391 · see citing works

Interleukin-2 and interleukin-6 in schizophrenia and mania: Effects of neuroleptics and mood stabilizers

Maes, M. H. J., Bosmans, E., Calabrese, J. R., Smith, R. S., & Meltzer, H. Y. (1995) · Journal of Psychiatric Research · doi:10.1016/0022-3956(94)00049-w · Cited by 385 · see citing works

Omega-3 Fatty Acids and Mood Disorders

Parker, G. B., Gibson, N. A., Brotchie, H., Heruc, G. A., Rees, A.-M., & Hadži-Pavlović, D. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.6.969 · Cited by 385 · see citing works

Voxelwise Meta-Analysis of Gray Matter Abnormalities in Bipolar Disorder

Bora, E., Fornito, A., Yücel, M., & Pantelis, C. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.01.020 · Cited by 378 · see citing works

Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder

Kim, Y.-K., Jung, H.-G., Myint, A.-M., Kim, H., & Park, S.-H. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.02.018 · Cited by 375 · see citing works

Ventricular and Periventricular Structural Volumes in First- Versus Multiple-Episode Bipolar Disorder

Strakowski, S. M., DelBello, M. P., Zimmerman, M. E., Getz, G. E., Mills, N. P., Ret, J., Shear, P. K., & Adler, C. M. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.11.1841 · Cited by 363 · see citing works

The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons

Yasuda, S., Liang, M.-H., Marinova, Z., Yahyavi, A., & Chuang, D.-M. (2009) · Molecular Psychiatry · doi:10.1038/sj.mp.4002099 · Cited by 358 · see citing works

Neuropsychological deficits and functional impairment in bipolar depression, hypomania and euthymia

Malhi, G. S., Ivanovski, B., Hadzi‐Pavlovic, D., Mitchell, P. B., Vieta, E., & Sachdev, P. S. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00324.x · Cited by 356 · see citing works

Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs

Maes, M. H. J., Delange, J., Ranjan, R., Meltzer, H. Y., Desnyder, R., Cooremans, W., & Scharpé, S. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(96)02915-0 · Cited by 341 · see citing works

Neuroplasticity and cellular resilience in mood disorders

Manji, H. K., Moore, G. J., Rajkowska, G., & Chen, G. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000811 · Cited by 339 · see citing works

Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes

Tavares, R. G., Tasca, C. I., Santos, C. E. S., Alves, L. B., Porciúncula, L. O., Emanuelli, T., & Souza, D. O. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(01)00133-4 · Cited by 320 · see citing works

Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: A possible role for lithium antioxidant effects

Machado‐Vieira, R., Andreazza, A. C., Viale, C. I., Zanatto, V. C., Ceresér, V. H., Vargas, R. D. S., Kapczinski, F. P., Portela, L. V., Souza, D. O., Salvador, M. M., et al. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.05.016 · Cited by 314 · see citing works

Serum S100B and antioxidant enzymes in bipolar patients

Andreazza, A. C., Cassini, C., Rosa, A. R., Leite, M. C., de Almeida, L. M. V., Nardin, P., da Cunha, A. B., Ceresér, K. M. M., Santin, A. M. P., Gottfried, C., et al. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.07.013 · Cited by 307 · see citing works

Kindling and sensitization as models for affective episode recurrence, cyclicity, and tolerance phenomena

Post, R. M. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.04.003 · Cited by 303 · see citing works

Mitochondrial involvement in psychiatric disorders

Shao, L., Martin, M. V., Watson, S. J., Schatzberg, A. F., Akil, H., Myers, R., Jones, E. G., Bunney, W. E., & Vawter, M. P. (2008) · Annals of Medicine · doi:10.1080/07853890801923753 · Cited by 303 · see citing works

Regional cerebral cortical thinning in bipolar disorder

Lyoo, I. K., Sung, Y. H., Dager, S. R., Friedman, S. D., Lee, J., Kim, S. J., Kim, N., Dünner, D. L., & Renshaw, P. F. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00284.x · Cited by 303 · see citing works

N-Acetyl Cysteine, a Glutamate-Modulating Agent, in the Treatment of Pathological Gambling: A Pilot Study

Grant, J. E., Kim, S. W., & Odlaug, B. L. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.11.021 · Cited by 302 · see citing works

Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double‐blind, randomized, placebo‐controlled study

Nery, F. G., Monkul, E. S., Hatch, J. P., Fonseca, M., Zunta‐Soares, G. B., Frey, B. N., Bowden, C. L., & Soares, J. C. (2008) · Human Psychopharmacology: Clinical and Experimental · doi:10.1002/hup.912 · Cited by 298 · see citing works

Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?

Ross, B. M., Seguin, J., & Sieswerda, L. E. (2007) · Lipids in Health and Disease · doi:10.1186/1476-511x-6-21 · Cited by 275 · see citing works

On the epigenetic regulation of the human reelin promoter

Chen, Y. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf401 · Cited by 274 · see citing works

Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia

Wang, J., Shao, L., Sun, X., & Young, L. T. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00717.x · Cited by 270 · see citing works

Adjuvant Aspirin Therapy Reduces Symptoms of Schizophrenia Spectrum Disorders

Laan, W., Grobbee, D. E., Selten, J., Heijnen, C. J., Kahn, R. S., & Burger, H. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09m05117yel · Cited by 265 · see citing works

Increased gray matter volume in lithium-treated bipolar disorder patients

Sassi, R. B., Nicoletti, M., Brambilla, P., Mallinger, A. G., Frank, E., Kupfer, D. J., Keshavan, M. S., & Soares, J. C. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00615-8 · Cited by 263 · see citing works

The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder.

Drexhage, R. C., Knijff, E. M., Padmos, R. C., Heul-Nieuwenhuijzen, L. V. D., Beumer, W., Versnel, M. A., & Drexhage, H. A. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.144 · Cited by 263 · see citing works

Coupling of Dopamine Oxidation (Monoamine Oxidase Activity) to Glutathione Oxidation Via the Generation of Hydrogen Peroxide in Rat Brain Homogenates

Maker, H. S., Weiss, C., Silides, D. J., & Cohen, G. (1981) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1981.tb01631.x · Cited by 256 · see citing works

Immune variations in bipolar disorder: phasic differences

Ortiz‐Domínguez, A., Hernández, M. E., Berlanga, C., Gutiérrez‐Mora, D., Moreno, J., Heinze, G., & Pavón, L. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00493.x · Cited by 255 · see citing works

Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia

Behrens, M. M., Ali, S. S., & Dugan, L. L. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4457-08.2008 · Cited by 241 · see citing works

Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder

Miller, C. L., Llenos, I. C., Dulay, J. R., & Weis, S. (2006) · Brain Research · doi:10.1016/j.brainres.2005.12.056 · Cited by 240 · see citing works

Expression of brain‐derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs

Bai, O., Chlan‐Fourney, J., Bowen, R., Keegan, D. A., & Li, X. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10440 · Cited by 239 · see citing works

Setting the stage: from prodrome to treatment resistance in bipolar disorder

Berk, M., Conus, P., Lucas, N., Hallam, K. T., Malhi, G. S., Dodd, S., Yatham, L. N., Yung, A. R., & McGorry, P. D. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00484.x · Cited by 239 · see citing works

Α Review on the Acute Phase Response in Major Depression

Maes, M. (1993) · Reviews in the Neurosciences · doi:10.1515/revneuro.1993.4.4.407 · Cited by 239 · see citing works

Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder

Sun, X., Wang, J., Tseng, M., & Young, L. T. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0623 · Cited by 238 · see citing works

MRI Analysis of the Cerebellum in Bipolar Disorder A Pilot Study

DelBello, M. P. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00026-3 · Cited by 234 · see citing works

Protective Effects of Lamotrigine, Aripiprazole and Escitalopram on Depression-induced Oxidative Stress in Rat Brain

Eren, İ., Nazıroğlu, M., & Demirdaş, A. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9289-x · Cited by 234 · see citing works

Differential Effect of Number of Previous Episodes of Affective Disorder on Response to Lithium or Divalproex in Acute Mania

Swann, A. C., Bowden, C. L., Calabrese, J. R., Dilsaver, S. C., & Morris, D. D. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.8.1264 · Cited by 231 · see citing works

Oxidative stress and role of antioxidant and ω-3 essential fatty acid supplementation in schizophrenia

Mahadik, S. P., Evans, D. R., & Lal, H. (2001) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(00)00181-0 · Cited by 229 · see citing works

Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study

Mendlewicz, J., Kriwin, P., Oswald, P., Souery, D., Alboni, S., & Brunello, N. (2006) · International Clinical Psychopharmacology · doi:10.1097/00004850-200607000-00005 · Cited by 229 · see citing works

Decreased Plasma Brain Derived Neurotrophic Factor Levels in Unmedicated Bipolar Patients During Manic Episode

Machado‐Vieira, R., Dietrich, M. O., Leke, R., Cereser, V. H., Zanatto, V. C., Kapczinski, F. P., Souza, D. O., Portela, L. V., & Gentil, V. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.070 · Cited by 223 · see citing works

Increased Anterior Cingulate/Medial Prefrontal Cortical Glutamate and Creatine in Bipolar Depression

Frye, M. A., Watzl, J., Banakar, S., O’Neill, J., Mintz, J., Davanzo, P. A., Fischer, J., Chirichigno, J. W., Ventura, J., Elman, S., et al. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301387 · Cited by 221 · see citing works

Psychiatric Comorbidity in 36 Adults with Mitochondrial Cytopathies

Fattal, O., Link, J. N., Quinn, K. M., Cohen, B. H., & Franco, K. S. N. (2007) · CNS Spectrums · doi:10.1017/s1092852900015303 · Cited by 220 · see citing works

Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients

Kim, H., Rapoport, S. I., & Rao, J. S. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.11.010 · Cited by 210 · see citing works

Is Cocaine Desire Reduced by N -Acetylcysteine?

LaRowe, S. D., Myrick, H., Hedden, S. L., Mardikian, P. N., Saladin, M. E., McRae‐Clark, A. L., Brady, K. T., Kalivas, P. W., & Malcolm, R. J. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.7.1115 · Cited by 210 · see citing works

Toward theragnostics

Pène, F., Courtine, E., Cariou, A., & Mira, J. P. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181921349 · Cited by 204 · see citing works

3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder

Andreazza, A. C., Kapczinski, F. P., Kauer‐Sant’Anna, M., Walz, J. C., Bond, D. J., Gonçalves, C. A., Young, L. T., & Yatham, L. N. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0935 · Cited by 199 · see citing works

Sodium valproate inhibits production of TNF-α and IL-6 and activation of NF-κB

Ichiyama, T., Okada, K., Lipton, J. M., Matsubara, T., Hayashi, T., & Furukawa, S. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02439-7 · Cited by 196 · see citing works

Mitochondrial bioenergetics in aging

Lenaz, G., D’Aurelio, M., Merlo Pich, M., Genova, M. L., Ventura, B., Bovina, C., Formiggini, G., & Parenti Castelli, G. (2000) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00177-8 · Cited by 189 · see citing works

Electrophysiological and cognitive function in young euthymic patients with bipolar affective disorder

El-Badri, S. M., Ashton, C. H., Moore, P. B., Marsh, V. R., & Ferrier, I. N. (2001) · Bipolar Disorders · doi:10.1034/j.1399-5618.2001.030206.x · Cited by 186 · see citing works

Glutathione: a novel treatment target in psychiatry

Berk, M., Ng, F., Dean, O., Dodd, S., & Bush, A. I. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.05.001 · Cited by 183 · see citing works

Brain-derived neurotrophic factor and neuroplasticity in bipolar disorder

Kapczinski, F., Frey, B. N., Kauer-Sant’Anna, M., & Grassi-Oliveira, R. (2008) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.8.7.1101 · Cited by 181 · see citing works

Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons

Zou, J., Wang, Y.-X., Dou, F.-F., Lü, H.-Z., Ma, Z.-W., Lu, P.-H., & Xu, X.-M. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2009.12.021 · Cited by 181 · see citing works

An open-label trial of N-acetylcysteine for the treatment of cocaine dependence: A pilot study

Mardikian, P. N., LaRowe, S. D., Hedden, S., Kalivas, P. W., & Malcolm, R. J. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.10.001 · Cited by 179 · see citing works

Features Associated With the Delayed Initiation of Mood Stabilizers at Illness Onset in Bipolar Disorder

Goldberg, J. F., & Ernst, C. L. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n1105 · Cited by 175 · see citing works

Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders

Grayson, D. R., Kundakovic, M., & Sharma, R. P. (2010) · Molecular Pharmacology · doi:10.1124/mol.109.061333 · Cited by 171 · see citing works

The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders

Machado-Vieira, R., Manji, H. K., & Zarate, C. A. (2009) · The Neuroscientist · doi:10.1177/1073858409336093 · Cited by 171 · see citing works

Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: A decade of advance

Cherlyn, S. Y. T., Woon, P. S., Liu, J., Ong, W., Tsai, G., & Sim, K. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.01.002 · Cited by 165 · see citing works

TNF-α as a molecular target in bipolar disorder

Brietzke, E., & Kapczinski, F. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.01.006 · Cited by 163 · see citing works

Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate

Cui, J., Shao, L., Young, L. T., & Wang, J.-F. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.11.010 · Cited by 160 · see citing works

The potential utility of a staging model as a course specifier: A bipolar disorder perspective

Berk, M., Hallam, K. T., & McGorry, P. D. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.03.007 · Cited by 158 · see citing works

Neocortical Gray Matter Volume in First-Episode Schizophrenia and First-Episode Affective Psychosis: A Cross-Sectional and Longitudinal MRI Study

Nakamura, M., Salisbury, D. F., Hirayasu, Y., Sylvain Bouix, A., Pohl, K. M., Yoshida, T., Koo, M., Shenton, M. E., & McCarley, R. W. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.030 · Cited by 158 · see citing works

Elevated serum levels of C-reactive protein are associated with mania symptoms in outpatients with bipolar disorder

Dickerson, F., Stallings, C. R., Origoni, A. E., Boronow, J. J., & Yolken, R. H. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.02.018 · Cited by 157 · see citing works

The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-γ

Bian, Q., Kato, T. A., Monji, A., Hashioka, S., Mizoguchi, Y., Horikawa, H., & Kanba, S. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.06.031 · Cited by 155 · see citing works

Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder

Cheng, R., Juo, S. H., Loth, J. E., Nee, J., Iossifov, I. H., Blumenthal, R. L., Sharpe, L., Kanyas, K., Lerer, B., Lilliston, B. A., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001778 · Cited by 153 · see citing works

An imbalance in the production of IL‐1β and IL‐6 by monocytes of bipolar patients: restoration by lithium treatment

Knijff, E. M., Breunis, M. N., Kupka, R., de Wit, H. J., Ruwhof, C., Akkerhuis, G. W., Nolen, W. A., & Drexhage, H. A. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00444.x · Cited by 146 · see citing works

Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition

Jones, K. A., Bernice Porjesz, A., Almasy, L. A., Bierut, L. J., Goate, A., Wang, J. C. C., Dick, D. M., Hinrichs, A. L., Kwon, J. M., Rice, J. P., et al. (2004) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2004.02.004 · Cited by 142 · see citing works

Neurodevelopmental damage after prenatal infection: role of oxidative stress in the fetal brain

Lanté, F., Meunier, J., Guiramand, J., Maurice, T., Cavalier, M., de Jesus Ferreira, M.-C., Aimar, R., Cohen-Solal, C., Vignes, M., & Barbanel, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.01.027 · Cited by 140 · see citing works

Dopamine-induced oxidative stress in neurons with glutathione deficit: implication for schizophrenia

Grima, G. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00405-x · Cited by 140 · see citing works

Misdiagnosed Patients With Bipolar Disorder

Matza, L. S., Rajagopalan, K., Thompson, C. L., & de Lissovoy, G. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n1114 · Cited by 137 · see citing works

Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E2 concentration in rat brain

Bosetti, F., Rintala, J., Seemann, R., Rosenberger, T. A., Contreras, M. A., Рапопорт, С. И., & Chang, M. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001111 · Cited by 137 · see citing works

Lithium‐induced enhancement of mitochondrial oxidative phosphorylation in human brain tissue

Maurer, I., Schippel, P., & Volz, H. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00729.x · Cited by 136 · see citing works

Brain-derived neurotrophic factor serum levels before and after treatment for acute mania

Tramontina, J., Andreazza, A. C., Kauer‐Sant’Anna, M., Stertz, L., Goi, J. D., Chiarani, F., & Kapczinski, F. P. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.01.028 · Cited by 136 · see citing works

Confirmation of association between the Val66Met polymorphism in the brain‐derived neurotrophic factor (BDNF) gene and bipolar I disorder

Lohoff, F. W., Sander, T., Ferraro, T. N., Dahl, J. P., Gallinat, J., & Berrettini, W. H. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30215 · Cited by 136 · see citing works

High-Sensitivity C-Reactive Protein and Fracture Risk in Elderly Women

Pasco, J. A., Kotowicz, M. A., Henry, M. J., Nicholson, G. C., Spilsbury, H. J., Box, J. D., & Schneider, H. G. (2006) · JAMA · doi:10.1001/jama.296.11.1353 · Cited by 134 · see citing works

Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders

Kato, T., Iwamoto, K., Kakiuchi, C., Kuratomi, G., & Okazaki, Y. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001662 · Cited by 130 · see citing works

Pro-inflammatory biomakers in depression: Treatment with venlafaxine

Piletz, J. E., Halaris, A. E., Iqbal, O., Hoppensteadt, D., Fareed, J., Zhu, H., Sinacore, J. M., & DeVane, C. L. (2009) · The World Journal of Biological Psychiatry · doi:10.3109/15622970802573246 · Cited by 130 · see citing works

Targeting Glycogen Synthase Kinase-3 in the CNS: Implications for the Development of New Treatments for Mood Disorders

Gould, T. D., Picchini, A. M., Einat, H., & Manji, H. K. (2006) · Current Drug Targets · doi:10.2174/1389450110607011399 · Cited by 129 · see citing works

Abnormalities in serum chemokine levels in euthymic patients with Bipolar Disorder

Brietzke, E. M., Kauer‐Sant’Anna, M., Teixeira, A. L., & Kapczinski, F. P. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.04.008 · Cited by 127 · see citing works

Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis

Fernandes, B. S., Gama, C. S., Kauer‐Sant’Anna, M., Lobato, M. I. R., Belmonte-de-Abreu, P. S., & Kapczinski, F. P. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.04.010 · Cited by 124 · see citing works

Oxidative stress parameters after combined fluoxetine and acetylsalicylic acid therapy in depressive patients

Gałecki, P., Szemraj, J., Bieńkiewicz, M., Zboralski, K., & Gałecka, E. (2009) · Human Psychopharmacology: Clinical and Experimental · doi:10.1002/hup.1014 · Cited by 124 · see citing works

Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease

Jicha, G. A., Berenfeld, B., & Davies, P. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990315)55:6 · Cited by 123 · see citing works

Prediction of relapse in recurrent affective disorder.

Zis, A. P., Grof, P., Webster, M. H., & Fk, G. (1980) · PubMed · Cited by 119 · see citing works

A systemic toxicity index developed to assess peripheral changes in mood episodes

Kapczinski, F., Dal-Pizzol, F., Teixeira, A. L., Magalhaes, P. V. S., Kauer-Sant'Anna, M., Klamt, F., de Bittencourt Pasquali, M. A., Quevedo, J., Gama, C. S., & Post, R. (2010) · Molecular Psychiatry · doi:10.1038/mp.2009.112 · Cited by 117 · see citing works

Ethyl-Eicosapentaenoic Acid in First-Episode Psychosis. A 1H-MRS Study

Berger, G. E., Wood, S. J., Wellard, R. M., Proffitt, T., McConchie, M., Amminger, G. P., Jackson, G. D., Velakoulis, D., Pantelis, C., & McGorry, P. D. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301628 · Cited by 116 · see citing works

Neuronal Correlates of Brain-derived Neurotrophic Factor Val66Met Polymorphism and Morphometric Abnormalities in Bipolar Disorder

Matsuo, K., Walss‐Bass, C., Nery, F. G., Nicoletti, M., Hatch, J. P., Frey, B. N., Monkul, E. S., Zunta‐Soares, G. B., Bowden, C. L., Escamilla, M. A., et al. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.23 · Cited by 115 · see citing works

Quetiapine reverses the suppression of hippocampal neurogenesis caused by repeated restraint stress

Luo, C., Xu, H., & Li, X. (2005) · Brain Research · doi:10.1016/j.brainres.2005.09.043 · Cited by 114 · see citing works

Mitochondrial Dysfunction as the Molecular Basis of Bipolar Disorder

Kato, T. (2007) · CNS Drugs · doi:10.2165/00023210-200721010-00001 · Cited by 113 · see citing works

Early onset of lithium prophylaxis as a predictor of good long-term outcome

Franchini, L., Zanardi, R., Smeraldi, E., & Gasperini, M. (1999) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s004060050091 · Cited by 113 · see citing works

Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients

Oliveira, G. S., Ceresér, K. M. M., Fernandes, B. S., Kauer‐Sant’Anna, M., Fries, G. R., Stertz, L., de Aguiar, B. W., Pfaffenseller, B., & Kapczinski, F. P. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.04.002 · Cited by 111 · see citing works

Regionally-specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorder

Dean, B., Tawadros, N., Scarr, E., & Gibbons, A. S. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.04.027 · Cited by 110 · see citing works

The Catecholamine–Cytokine Balance

Szelényi, J., & Vizi, E. S. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1391.026 · Cited by 109 · see citing works

Increased oxidative stress after repeated amphetamine exposure: possible relevance as a model of mania

Frey, B. N., Martins, M. R., Petronilho, F. C., Dal‐Pizzol, F., Quevedo, J., & Kapczinski, F. P. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00318.x · Cited by 109 · see citing works

Inflammatory Markers in Schizophrenia: Comparing Antipsychotic Effects in Phase 1 of the Clinical Antipsychotic Trials of Intervention Effectiveness Study

Meyer, J. M., McEvoy, J. P., Davis, V. G., GOFF, D. C., Nasrallah, H. A., Thomas, S., Hsiao, J., Swartz, M. S., Stroup, T. S., & Lieberman, J. A. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.06.005 · Cited by 108 · see citing works

Leptin in depressed women: Cross-sectional and longitudinal data from an epidemiologic study

Pasco, J. A., Jacka, F. N., Williams, L. J., Henry, M. J., Nicholson, G. C., Kotowicz, M. A., & Berk, M. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.07.024 · Cited by 107 · see citing works

Chronic Carbamazepine Decreases the Incorporation Rate and Turnover of Arachidonic Acid but Not Docosahexaenoic Acid in Brain Phospholipids of the Unanesthetized Rat: Relevance to Bipolar Disorder

Bazinet, R. P., Rao, J. S., Chang, L., Rapoport, S. I., & Lee, H. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.07.024 · Cited by 106 · see citing works

Tryptophan breakdown pathway in bipolar mania

Myint, A.-M., Kim, Y., Verkerk, R. M., Park, S. H., Scharpé, S., Steinbusch, H. W. M., & Leonard, B. E. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.12.008 · Cited by 106 · see citing works

Serological observations in patients suffering from acute manic episodes

Wadee, A. A., Kuschke, R. H., Wood, L. A., Berk, M., Ichim, L., & Maes, M. H. J. (2002) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.390 · Cited by 104 · see citing works

Acetylsalicylic acid accelerates the antidepressant effect of fluoxetine in the chronic escape deficit model of depression

Brunello, N., Alboni, S., Capone, G., Benatti, C., Blom, J. M. C., Tascedda, F., Kriwin, P., & Mendlewicz, J. (2006) · International Clinical Psychopharmacology · doi:10.1097/00004850-200607000-00004 · Cited by 104 · see citing works

The nature of bipolar disorder.

Manji, H. K., & Lenox, R. H. (2000) · PubMed · Cited by 104 · see citing works

Increased serum glial cell line-derived neurotrophic factor immunocontent during manic and depressive episodes in individuals with bipolar disorder

Rosa, A. R., Frey, B. N., Andreazza, A. C., Ceresér, K. M., Cunha, A. B. M., Quevedo, J., Santin, A. M. P., Gottfried, C., Gonçalves, C. A., Vieta, E., et al. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.08.026 · Cited by 102 · see citing works

Omega-3 fatty acids for bipolar disorder

Montgomery, P., & Richardson, A. J. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005169.pub2 · Cited by 101 · see citing works

Protective effects of atypical antipsychotic drugs on PC12 cells after serum withdrawal

Bai, O., Wei, Z., Lu, W., Bowen, R., Keegan, D. A., & Li, X. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10290 · Cited by 98 · see citing works

Changes in Antioxidant Defense Enzymes after d-amphetamine Exposure: Implications as an Animal Model of Mania

Frey, B. N., Valvassori, S. S., Réus, G. Z., Martins, M. R., Petronilho, F. C., Bardini, K., Dal‐Pizzol, F., Kapczinski, F. P., & Quevedo, J. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9070-6 · Cited by 98 · see citing works

Brain lithium, N‐acetyl aspartate and myo‐inositol levels in older adults with bipolar disorder treated with lithium: a lithium‐7 and proton magnetic resonance spectroscopy study

Forester, B. P., Finn, C. T., Berlow, Y. A., Wardrop, M., Renshaw, P. F., & Moore, C. M. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00627.x · Cited by 98 · see citing works

Magnetic Resonance Spectroscopy and its Applications in Psychiatry

Malhi, G. S., Valenzuela, M., Wen, W. X., & Sachdev, P. S. (2002) · Australian & New Zealand Journal of Psychiatry · doi:10.1046/j.1440-1614.2002.00992.x · Cited by 97 · see citing works

Dopamine efflux by MPTP and hydroxyl radical generation

Obata, T. (2002) · Journal of Neural Transmission · doi:10.1007/s00702-001-0683-2 · Cited by 96 · see citing works

Clinical Implications of the Cytokine Hypothesis of Depression: The Association between Use of Statins and Aspirin and the Risk of Major Depression

Pasco, J. A., Jacka, F. N., Williams, L. J., Henry, M. J., Nicholson, G. C., Kotowicz, M. A., & Berk, M. (2010) · Psychotherapy and Psychosomatics · doi:10.1159/000319530 · Cited by 95 · see citing works

The Use of Statins After a Cardiac Intervention Is Associated With Reduced Risk of Subsequent Depression

Stafford, L., & Berk, M. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09m05825blu · Cited by 93 · see citing works

Decreased muscarinic receptor binding in the frontal cortex of bipolar disorder and major depressive disorder subjects

Gibbons, A. S., Scarr, E., McLean, C., Sundram, S., & Dean, B. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.11.015 · Cited by 93 · see citing works

Predictors of recurrence in affective disorder

Kessing, L. V., Andersen, P. K., & Mortensen, P. B. (1998) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00163-8 · Cited by 91 · see citing works

First-Episode Mania: A Neglected Priority for Early Intervention

Conus, P., Conus, P., & McGorry, P. D. (2002) · Australian & New Zealand Journal of Psychiatry · doi:10.1046/j.1440-1614.2002.00994.x · Cited by 88 · see citing works

Lithium Upregulates Vascular Endothelial Growth Factor in Brain Endothelial Cells and Astrocytes

Guo, S., Arai, K., Stins, M. F., Chuang, D., & Lo, E. H. (2008) · Stroke · doi:10.1161/strokeaha.108.524504 · Cited by 86 · see citing works

Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus

Bai, O., Zhang, H., & Li, X. (2004) · Brain Research · doi:10.1016/j.brainres.2004.02.064 · Cited by 86 · see citing works

Serotonergic and Noradrenergic Markers of Post-Traumatic Stress Disorder with and without Major Depression

Maes, M. H. J. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00058-x · Cited by 86 · see citing works

Chronic Administration of Mood Stabilizers Upregulates BDNF and Bcl-2 Expression Levels in Rat Frontal Cortex

Chang, Y. C., Rapoport, S. I., & Rao, J. S. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9817-3 · Cited by 86 · see citing works

Lipid Peroxidation Products Inhibit Dopamine Catabolism Yielding Aberrant Levels of a Reactive Intermediate

Rees, J., Florang, V. R., Anderson, D. G., & Doorn, J. A. (2007) · Chemical Research in Toxicology · doi:10.1021/tx700248y · Cited by 83 · see citing works

The Vagus Nerve and Nicotinic Receptors Involve Inhibition of HMGB1 Release and Early Pro-inflammatory Cytokines Function in Collagen-Induced Arthritis

Li, T., Zuo, X., Zhou, Y., Wang, Y., Zhuang, H., Zhang, L., Zhang, H., & Xiao, X. (2009) · Journal of Clinical Immunology · doi:10.1007/s10875-009-9346-0 · Cited by 79 · see citing works

Decreased Glutamate/Glutamine Levels May Mediate Cytidine’s Efficacy in Treating Bipolar Depression: A Longitudinal Proton Magnetic Resonance Spectroscopy Study

Yoon, S. J., Lyoo, I. K., Haws, C. A., Kim, T. S., Cohen, B. M., & Renshaw, P. F. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.2 · Cited by 78 · see citing works

Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder

Fornito, A., Yücel, M., Wood, S. J., Bechdolf, A., Carter, S., Adamson, C. L., Velakoulis, D., Saling, M. M., McGorry, P. D., & Pantelis, C. (2009) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.107.049205 · Cited by 77 · see citing works

Effects of quetiapine on the brain-derived neurotrophic factor expression in the hippocampus and neocortex of rats

Park, S.-W., Lee, S.-K., Kim, J.-M., Yoon, J., & Kim, Y.-H. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.03.028 · Cited by 74 · see citing works

The platelet as a peripheral marker in psychiatric illness

Plein, H., & Berk, M. (2001) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.251 · Cited by 71 · see citing works

A Comparative Proteomics Analysis of Rat Mitochondria from the Cerebral Cortex and Hippocampus in Response to Antipsychotic Medications

Ji, B., La, Y., Gao, L., Zhu, H., Tian, N., Zhang, M., Yang, Y., Zhao, X., Tang, R., Ma, G., et al. (2009) · Journal of Proteome Research · doi:10.1021/pr800876z · Cited by 70 · see citing works

Chronic treatment of rats with sodium valproate downregulates frontal cortex NF‐κB DNA binding activity and COX‐2 mRNA1

Rao, J. S., Bazinet, R. P., Rapoport, S. I., & Lee, H. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00361.x · Cited by 70 · see citing works

Serum neurotrophin-3 is increased during manic and depressive episodes in bipolar disorder

Walz, J. C., Andreazza, A. C., Frey, B. N., de Cacilhas, A. A., Ceresér, K. M. M., Cunha, A. B. M., Weyne, F., Stertz, L., Santin, A. M. P., Gonçalves, C. A., et al. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.01.002 · Cited by 66 · see citing works

Association between brain‐derived neurotrophic factor gene and a severe form of bipolar disorder, but no interaction with the serotonin transporter gene

Vincze, I., Perroud, N. A., Burési, C., Baud, P., Bellivier, F., Étain, B., Fournier, C., Karege, F., Matthey, M., Preisig, M., et al. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00603.x · Cited by 66 · see citing works

The specificity of platelet glutamate receptor supersensitivity in psychotic disorders

Berk, M., Plein, H., & Belsham, B. (2000) · Life Sciences · doi:10.1016/s0024-3205(00)80002-8 · Cited by 64 · see citing works

Antidepressant-like effects of N-acetyl-L-cysteine in rats

Ferreira, F. R., Biojone, C., Joca, S. R. L., & Guimarães, F. S. (2008) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3283123c98 · Cited by 63 · see citing works

Depression and Bone Metabolism

Williams, L. J., Pasco, J. A., Jacka, F. N., Henry, M. J., Dodd, S., & Berk, M. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000162297 · Cited by 63 · see citing works

Synergy between Tumor Necrosis Factor α and Interleukin 1β in Inducing Transcriptional Down-regulation of Muscarinic M2 Receptor Gene Expression

Haddad, E., Rousell, J., Lindsay, M. A., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.51.32586 · Cited by 63 · see citing works

Evidence That Oxidative Stress-Induced Apoptosis by Menadione Involves Fas-Dependent and Fas-Independent Pathways

Laux, I., & Nel, A. E. (2001) · Clinical Immunology · doi:10.1006/clim.2001.5129 · Cited by 63 · see citing works

Neuroprotection in emerging psychotic disorders

Berger, G., Dell'olio, M., Amminger, P., Cornblatt, B., Phillips, L., Yung, A., Yan, Y., Berk, M., & McGorry, P. (2007) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2007.00021.x · Cited by 62 · see citing works

In vivo evidence for early neurodevelopmental anomaly of the anterior cingulate cortex in bipolar disorder

Fornito, A., Malhi, G. S., Lagopoulos, J., Ivanovski, B., Wood, S. J., Velakoulis, D., Saling, M. M., McGorry, P. D., Pantelis, C., & Yücel, M. (2007) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.01069.x · Cited by 62 · see citing works

Effect of MK-801 and ketamine on hydroxyl radical generation in the posterior cingulate and retrosplenial cortex of free-moving mice, as determined by in vivo microdialysis

Zuo, D., Wu, Y., Yao, W.-X., Cao, Y., Wu, C., & Tanaka, M. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.05.010 · Cited by 61 · see citing works

Brain-Derived Tumor Necrosis Factor-α and Its Involvement in Noradrenergic Neuron Functioning Involved in the Mechanism of Action of an Antidepressant

Reynolds, J. L., Ignatowski, T. A., Sud, R., & Spengler, R. N. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.067835 · Cited by 61 · see citing works

Gray matter deficits in bipolar disorder are associated with genetic variability at interleukin‐1 beta gene (2q13)

Papiol, S., Molina, V., Desco, M., Rosa, A., Reig, S., Sanz, J., Palomo, T., & Fañanás, L. (2008) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2008.00421.x · Cited by 59 · see citing works

Effect of inflammatory cell mediators on M2 muscarinic receptors in the lungs

Fryer, A. D., & Jacoby, D. B. (1993) · Life Sciences · doi:10.1016/0024-3205(93)90311-p · Cited by 57 · see citing works

Towards innovative international classification and diagnostic systems: ICD‐11 and person‐centered integrative diagnosis

Mezzich, J. E., & Salloum, I. M. (2007) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.01028.x · Cited by 55 · see citing works

NEURODEVELOPMENTAL AND NEUROPROGRESSIVE PROCESSES IN SCHIZOPHRENIA

Waddington, J. L., Lane, A., Scully, P. J., Larkin, C., & O’Callaghan, E. (1998) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70364-6 · Cited by 54 · see citing works

Increased serum neurotrophin-4/5 levels in bipolar disorder

Walz, J. C., Magalhães, P. V. D. S., Giglio, L. M. F., Cunha, A. B. M., Stertz, L., Fries, G. R., Andreazza, A. C., & Kapczinski, F. P. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2008.10.005 · Cited by 54 · see citing works

The Effect of Antiepileptic Drugs on Mitochondrial Activity: A Pilot Study

Berger, I., Segal, I., Shmueli, D., & Saada, A. (2010) · Journal of Child Neurology · doi:10.1177/0883073809352888 · Cited by 51 · see citing works

Mechanisms of proton transfer in proteins: Localized charge transfer versus delocalized soliton transfer

Stuchebrukhov, A. A. (2009) · Physical Review E · doi:10.1103/physreve.79.031927 · Cited by 49 · see citing works

Attenuation of Lipopolysaccharide-Induced Inflammatory Response and Phospholipids Metabolism at the Feto-Maternal Interface by N-Acetyl Cysteine

Paintlia, M. K., Paintlia, A. S., Singh, A. K., & Singh, I. (2008) · Pediatric Research · doi:10.1203/pdr.0b013e318181e07c · Cited by 49 · see citing works

Neurotoxicity of tryptophan metabolites

Smith, A. J., Stone, T. W., & Smith, R. A. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351287 · Cited by 46 · see citing works

Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death

Kim, Y. J., Ko, H. H., Han, E. S., & Lee, C. S. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.12.006 · Cited by 46 · see citing works

ASPIRIN USE, DEPRESSION, AND COGNITIVE IMPAIRMENT IN LATER LIFE: THE HEALTH IN MEN STUDY

Almeida, O. P., Alfonso, H. S., Jamrozik, K. D., Hankey, G. J., & Flicker, L. A. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02827.x · Cited by 44 · see citing works

The platelet intracellular calcium response to serotonin is augmented in bipolar manic and depressed patients

Berk, M., Bodemer, W., Oudenhove, T. V., & Butkow, N. (1995) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470100304 · Cited by 44 · see citing works

Efficacy of Atypical Antipsychotics in Bipolar Disorder

Berk, M., & Dodd, S. (2005) · Drugs · doi:10.2165/00003495-200565020-00006 · Cited by 44 · see citing works

Effects of N-acetyl-cysteine on the survival and regeneration of sural sensory neurons in adult rats

Welin, D., Novikova, L. N., Wiberg, M., Kellerth, J., & Novikov, L. N. (2009) · Brain Research · doi:10.1016/j.brainres.2009.06.038 · Cited by 43 · see citing works

Role of cholinergic anti-inflammatory pathway in regulating host response and its interventional strategy for inflammatory diseases.

Wang, D., Zhou, R., & Yao, Y.-M. (2009) · PubMed · Cited by 41 · see citing works

Modulation of peroxisome proliferator‐activated receptor‐α activity by N‐acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures

Paintlia, M. K., Paintlia, A. S., Khan, M., Singh, I., & Singh, A. K. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05199.x · Cited by 41 · see citing works

Efficacy of Omega-3 Fatty Acid Supplementation on Improvement of Bipolar Symptoms: A Systematic Review

Turnbull, T., Cullen-Drill, M., & Smaldone, A. M. (2008) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2008.02.011 · Cited by 39 · see citing works

Chronic Administration of Lamotrigine Downregulates COX-2 mRNA and Protein in Rat Frontal Cortex

Lee, H., Ertley, R. N., Rapoport, S. I., Bazinet, R. P., & Rao, J. S. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9526-3 · Cited by 38 · see citing works

Relationship of Serum Leptin to Total and Truncal Body Fat

Solin, M. S., Ball, M. J., Robertson, I. K., et al. (1997) · Clinical Science · doi:10.1042/cs0930581 · Cited by 36 · see citing works

Chronic Lithium Salt Treatment Reduces CRE/CREB-Directed Gene Transcription and Reverses Its Upregulation by Chronic Psychosocial Stress in Transgenic Reporter Gene Mice

Böer, U., Cierny, I., Krause, D., Heinrich, A., Lin, H., Mayr, G. W., Hiemke, C., & Knepel, W. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301640 · Cited by 35 · see citing works

Bipolar disorder

Grande, I., Berk, M., Birmaher, B., & Vieta, E. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00241-x · Cited by 1,710 · see citing works

Bipolar disorders

McIntyre, R. S., Berk, M., Brietzke, E., Goldstein, B. I., López-Jaramillo, C., Kessing, L. V., Malhi, G. S., Nierenberg, A. A., Rosenblat, J. D., Majeed, A., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31544-0 · Cited by 1,047 · see citing works

Bipolar disorders

Vieta, E., Berk, M., Schulze, T. G., Carvalho, A. F., Suppes, T., Calabrese, J. R., Gao, K., Miskowiak, K. W., & Grande, I. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2018.8 · Cited by 891 · see citing works

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

Leonard, B., & Maes, M. (2012) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.005 · Cited by 805 · see citing works

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750 · see citing works

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

Maes, M., Berk, M., Goehler, L., Song, C., Anderson, G., Gałecki, P., & Leonard, B. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-66 · Cited by 629 · see citing works

Cytokine Alterations in Bipolar Disorder: A Meta-Analysis of 30 Studies

Modabbernia, A., Taslimi, S., Brietzke, E., & Ashrafi, M. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.007 · Cited by 596 · see citing works

Bipolar Disorder

Carvalho, A. F., Firth, J., & Vieta, E. (2020) · New England Journal of Medicine · doi:10.1056/nejmra1906193 · Cited by 562 · see citing works

The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications

Moylan, S., Maes, M., Wray, N. R., & Berk, M. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.33 · Cited by 529 · see citing works

The Devastating Clinical Consequences of Child Abuse and Neglect: Increased Disease Vulnerability and Poor Treatment Response in Mood Disorders

Lippard, E. T. C., & Nemeroff, C. B. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19010020 · Cited by 527 · see citing works

Oxidative stress, inflammation and treatment response in major depression

Lindqvist, D., Dhabhar, F. S., James, S. J., Hough, C. M., Jain, F. A., Bersani, F. S., Reus, V. I., Verhoeven, J. E., Epel, E. S., Mahan, L., et al. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.11.031 · Cited by 473 · see citing works

Lifestyle medicine for depression

Sarris, J., O’Neil, A., Coulson, C. E., Schweitzer, I., & Berk, M. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-107 · Cited by 450 · see citing works

Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut

Maes, M., Kubera, M., Leunis, J.-C., & Berk, M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.02.023 · Cited by 446 · see citing works

Childhood maltreatment and inflammatory markers: a systematic review.

Coelho, R., Viola, T. W., Walss‐Bass, C., Brietzke, E., & Grassi‐Oliveira, R. (2014) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12217 · Cited by 426 · see citing works

Gut microbiota in autism and mood disorders

Mangiola, F. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i1.361 · Cited by 413 · see citing works

Cytokines in bipolar disorder vs. healthy control subjects: A systematic review and meta-analysis

Munkholm, K., Braüner, J. V., Kessing, L. V., & Vinberg, M. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.05.018 · Cited by 402 · see citing works

Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma?

Danese, A., & J Lewis, S. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.198 · Cited by 393 · see citing works

A systematic review of randomised control trials on the effects of yoga on stress measures and mood

Pascoe, M. C., & Bauer, I. E. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.07.013 · Cited by 366 · see citing works

Has the time come for a staging model to map the course of eating disorders from high risk to severe enduring illness? An examination of the evidence

Treasure, J., Stein, D., & Maguire, S. (2015) · Early Intervention in Psychiatry · doi:10.1111/eip.12170 · Cited by 353 · see citing works

New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates—Nrf2 activators and GSK-3 inhibitors

Maes, M., Fišar, Z., Medina, M., Scapagnini, G., Nowak, G., & Berk, M. (2012) · Inflammopharmacology · doi:10.1007/s10787-011-0111-7 · Cited by 325 · see citing works

A double-blind, randomized, placebo-controlled trial of <i>Lactobacillus helveticus</i> and <i>Bifidobacterium longum</i> for the symptoms of depression

Romijn, A. R., Rucklidge, J. J., Kuijer, R. G., & Frampton, C. (2017) · Australian &amp; New Zealand Journal of Psychiatry · doi:10.1177/0004867416686694 · Cited by 323 · see citing works

Hidden wounds? inflammatory links between childhood trauma and psychopathology

Danese, A., & Baldwin, J. R. (2017) · Annual Review of Psychology · doi:10.1146/annurev-psych-010416-044208 · Cited by 286 · see citing works

Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: a meta-analysis of 52 studies

Fernandes, B. S., Molendijk, M. L., Köhler, C. A., Soares, J. C., Leite, C. M. G. S., Machado-Vieira, R., Ribeiro, T. L., Silva, J. C., Sales, P. M. G., Quevedo, J., et al. (2015) · BMC Medicine · doi:10.1186/s12916-015-0529-7 · Cited by 291 · see citing works

Bipolar Disorder and Immune Dysfunction: Epidemiological Findings, Proposed Pathophysiology and Clinical Implications

Rosenblat, J., & McIntyre, R. (2017) · Brain Sciences · doi:10.3390/brainsci7110144 · Cited by 258 · see citing works

Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value

Scott, J., Leboyer, M., Hickie, I., Berk, M., Kapczinski, F., Frank, E., Kupfer, D., & McGorry, P. (2013) · British Journal of Psychiatry · doi:10.1192/bjp.bp.112.110858 · Cited by 260 · see citing works

Cytokines in bipolar disorder: A systematic review and meta-analysis

Munkholm, K., Vinberg, M., & Vedel Kessing, L. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.06.010 · Cited by 256 · see citing works

Dysregulated relationship of inflammation and oxidative stress in major depression

Rawdin, B. J., Mellon, S. H., Dhabhar, F. S., Epel, E. S., Puterman, E., Su, Y., Burke, H. M., Reus, V. I., Rosser, R., Hamilton, S. P., et al. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2012.11.011 · Cited by 255 · see citing works

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

Morris, G., & Berk, M. (2015) · BMC Medicine · doi:10.1186/s12916-015-0310-y · Cited by 245 · see citing works

C-reactive protein concentrations across the mood spectrum in bipolar disorder: a systematic review and meta-analysis

Fernandes, B. S., Steiner, J., Molendijk, M. L., Dodd, S., Nardin, P., Gonçalves, C.-A., Jacka, F., Köhler, C. A., Karmakar, C., Carvalho, A. F., et al. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30370-4 · Cited by 247 · see citing works

Obesity and psychiatric disorders: Commonalities in dysregulated biological pathways and their implications for treatment

Lopresti, A. L., & Drummond, P. D. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.05.005 · Cited by 231 · see citing works

Biomarkers in bipolar disorder: a positional paper from the international society for bipolar disorders biomarkers task force.

Frey, B. N., Andreazza, A. C., Houenou, J., Jamain, S., Goldstein, B. I., Frye, M. A., Leboyer, M., Berk, M., Malhi, G. S., Lopez-Jaramillo, C., et al. (2013) · Australian &amp; New Zealand Journal of Psychiatry · doi:10.1177/0004867413478217 · Cited by 234 · see citing works

The “psychomicrobiotic”: targeting microbiota in major psychiatric disorders: a systematic review

Fond, G., Boukouaci, W., Chevalier, G., Regnault, A., Eberl, G., Hamdani, N., Dickerson, F., Macgregor, A., Boyer, L., Dargel, A., et al. (2015) · Pathologie Biologie · doi:10.1016/j.patbio.2014.10.003 · Cited by 219 · see citing works

Staging systems in bipolar disorder: an <scp>I</scp>nternational <scp>S</scp>ociety for <scp>B</scp>ipolar <scp>D</scp>isorders <scp>T</scp>ask <scp>F</scp>orce <scp>R</scp>eport

Kapczinski, F., Magalhães, P. V. S., Balanzá‐Martinez, V., Dias, V. V., Frangou, S., Gama, C. S., Gonzalez‐Pinto, A., Grande, I., Ha, K., Kauer‐Sant'Anna, M., et al. (2014) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12305 · Cited by 217 · see citing works

Staging in bipolar disorder: from theoretical framework to clinical utility

Berk, M., Post, R., Ratheesh, A., Gliddon, E., Singh, A., Vieta, E., Carvalho, A. F., Ashton, M. M., Berk, L., Cotton, S. M., et al. (2017) · World Psychiatry · doi:10.1002/wps.20441 · Cited by 216 · see citing works

The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials

Firth, J., Teasdale, S. B., Allott, K., Siskind, D., Marx, W., Cotter, J., Veronese, N., Schuch, F., Smith, L., Solmi, M., et al. (2019) · World Psychiatry · doi:10.1002/wps.20672 · Cited by 214 · see citing works

History of Bipolar Disorder and the Risk of Dementia: A Systematic Review and Meta-Analysis

Diniz, B. S., Teixeira, A. L., Cao, F., Gildengers, A., Soares, J. C., Butters, M. A., & Reynolds, C. F. (2017) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.11.014 · Cited by 191 · see citing works

Magnetic field effects in biology from the perspective of the radical pair mechanism

Zadeh-Haghighi, H., & Simon, C. (2022) · Journal of The Royal Society Interface · doi:10.1098/rsif.2022.0325 · Cited by 197 · see citing works

The Relationship Between Neurocognitive and Psychosocial Functioning in Major Depressive Disorder: A Systematic Review

Evans, V. C., Iverson, G. L., Yatham, L. N., & Lam, R. W. (2014) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.13r08939 · Cited by 185 · see citing works

How cigarette smoking may increase the risk of anxiety symptoms and anxiety disorders: a critical review of biological pathways

Moylan, S., Jacka, F. N., Pasco, J. A., & Berk, M. (2013) · Brain and Behavior · doi:10.1002/brb3.137 · Cited by 186 · see citing works

Bipolar Disorder: Role of Inflammation and the Development of Disease Biomarkers

Muneer, A. (2016) · Psychiatry Investigation · doi:10.4306/pi.2016.13.1.18 · Cited by 187 · see citing works

The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research

Rizzo, L. B., Costa, L. G., Mansur, R. B., Swardfager, W., Belangero, S. I., Grassi-Oliveira, R., McIntyre, R. S., Bauer, M. E., & Brietzke, E. (2014) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.02.004 · Cited by 183 · see citing works

Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: Evidence, pathophysiology and treatment implications

Rosenblat, J. D., Brietzke, E., Mansur, R. B., Maruschak, N. A., Lee, Y., & McIntyre, R. S. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.08.058 · Cited by 172 · see citing works

Oxidative stress in early stage Bipolar Disorder and the association with response to lithium

de Sousa, R. T., Zarate, C. A., Zanetti, M. V., Costa, A. C., Talib, L. L., Gattaz, W. F., & Machado-Vieira, R. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.11.011 · Cited by 169 · see citing works

Stage managing bipolar disorder

Berk, M., Berk, L., Dodd, S., Cotton, S., Macneil, C., Daglas, R., Conus, P., Bechdolf, A., Moylan, S., & Malhi, G. S. (2014) · Bipolar Disorders · doi:10.1111/bdi.12099 · Cited by 163 · see citing works

A model of the mitochondrial basis of bipolar disorder

Morris, G., Walder, K., McGee, S. L., Dean, O. M., Tye, S. J., Maes, M., & Berk, M. (2017) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.014 · Cited by 162 · see citing works

Persistence of cognitive impairment and its negative impact on psychosocial functioning in lithium-treated, euthymic bipolar patients: a 6-year follow-up study

Mora, E., Portella, M. J., Forcada, I., Vieta, E., & Mur, M. (2013) · Psychological Medicine · doi:10.1017/s0033291712001948 · Cited by 157 · see citing works

Peripheral blood brain-derived neurotrophic factor in bipolar disorder: a comprehensive systematic review and meta-analysis

Munkholm, K., Vinberg, M., & Kessing, L. V. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.54 · Cited by 157 · see citing works

Exercising the worry away: how inflammation, oxidative and nitrogen stress mediates the beneficial effect of physical activity on anxiety disorder symptoms and behaviours

Moylan, S., Eyre, H. A., Maes, M., Baune, B. T., Jacka, F. N., & Berk, M. (2013) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.003 · Cited by 155 · see citing works

IL-6, IL-18, SIL-2R, and TNFα Proinflammatory Markers in Depression and Schizophrenia Patients Who Are Free of Overt Inflammation

Al-Hakeim, H. K., Al-Rammahi, D. A., & Al-Dujaili, A. H. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.04.044 · Cited by 152 · see citing works

Viral infection, inflammation and schizophrenia

Kneeland, R. E., & Fatemi, S. H. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.02.001 · Cited by 152 · see citing works

The 2020 Royal Australian and New Zealand College of psychiatrists clinical practice guidelines for mood disorders: Bipolar disorder summary

Malhi, G. S., Bell, E., Boyce, P., Bassett, D., Berk, M., Bryant, R., Gitlin, M., Hamilton, A., Hazell, P., Hopwood, M., et al. (2020) · Bipolar Disorders · doi:10.1111/bdi.13036 · Cited by 152 · see citing works

Schizophrenia and inflammation research: a bibliometric analysis

Sun, H.-L., Bai, W., Li, X.-H., Huang, H., Cui, X.-L., Cheung, T., Su, Z.-H., Yuan, Z., Ng, C. H., & Xiang, Y.-T. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.907851 · Cited by 148 · see citing works

Interplay between the pro-oxidant and antioxidant systems and proinflammatory cytokine levels, in relation to iron metabolism and the erythron in depression

Rybka, J., Kędziora-Kornatowska, K., Banaś-Leżańska, P., Majsterek, I., Carvalho, L. A., Cattaneo, A., Anacker, C., & Kędziora, J. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.05.019 · Cited by 146 · see citing works

Pharmacological approaches in bipolar disorders and the impact on cognition: a critical overview

Dias, V. V., Balanzá‐Martinez, V., Soeiro‐de‐Souza, M. G., Moreno, R. A., Figueira, M. L., Machado‐Vieira, R., & Vieta, E. (2012) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2012.01910.x · Cited by 146 · see citing works

Inflammatory biomarker profiles of mental disorders and their relation to clinical, social and lifestyle factors

Baumeister, D., Russell, A., Pariante, C. M., & Mondelli, V. (2014) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-014-0887-z · Cited by 142 · see citing works

Targeting classical IL-6 signalling or IL-6<i>trans</i>-signalling in depression?

Maes, M., Anderson, G., Kubera, M., & Berk, M. (2014) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2014.888417 · Cited by 140 · see citing works

Oxidative stress markers in affective disorders

Siwek, M., Sowa-Kućma, M., Dudek, D., Styczeń, K., Szewczyk, B., Kotarska, K., Misztak, P., Pilc, A., Wolak, M., & Nowak, G. (2013) · Pharmacological Reports · doi:10.1016/s1734-1140(13)71517-2 · Cited by 142 · see citing works

Natural Withanolides in the Treatment of Chronic Diseases

White, P. T., Subramanian, C., Motiwala, H. F., & Cohen, M. S. (2016) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-319-41334-1_14 · Cited by 139 · see citing works

Physical Exercise for Treatment of Mood Disorders: A Critical Review

Hearing, C. M., Chang, W. C., Szuhany, K. L., Deckersbach, T., Nierenberg, A. A., & Sylvia, L. G. (2016) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-016-0089-y · Cited by 137 · see citing works

The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder

Elvsåshagen, T., Vera, E., Bøen, E., Bratlie, J., Andreassen, O. A., Josefsen, D., Malt, U. F., Blasco, M. A., & Boye, B. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.08.006 · Cited by 133 · see citing works

Minocycline: Therapeutic Potential in Psychiatry

Dean, O. M., Data-Franco, J., Giorlando, F., & Berk, M. (2012) · CNS Drugs · doi:10.2165/11632000-000000000-00000 · Cited by 131 · see citing works

Gut microbes in neurocognitive and mental health disorders

Halverson, T., & Alagiakrishnan, K. (2020) · Annals of Medicine · doi:10.1080/07853890.2020.1808239 · Cited by 125 · see citing works

Neurodevelopmental pathways in bipolar disorder

Kloiber, S., Rosenblat, J. D., Husain, M. I., Ortiz, A., Berk, M., Quevedo, J., Vieta, E., Maes, M., Birmaher, B., Soares, J. C., et al. (2020) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.02.005 · Cited by 122 · see citing works

A neuro-immune model of myalgic encephalomyelitis/chronic fatigue syndrome

Morris, G., & Maes, M. (2013) · Metabolic Brain Disease · doi:10.1007/s11011-012-9324-8 · Cited by 117 · see citing works

Increased autoimmune activity against 5-HT: A key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression

Maes, M., Ringel, K., Kubera, M., Berk, M., & Rybakowski, J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.11.016 · Cited by 116 · see citing works

Increased oxidative stress in prefrontal cortex and hippocampus is related to depressive-like behavior in streptozotocin-diabetic rats

de Morais, H., de Souza, C. P., da Silva, L. M., Ferreira, D. M., Werner, M. F., Andreatini, R., da Cunha, J. M., & Zanoveli, J. M. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.10.011 · Cited by 111 · see citing works

Inflammation as a treatment target in mood disorders: review

Jones, B. D. M., Daskalakis, Z. J., Carvalho, A. F., Strawbridge, R., Young, A. H., Mulsant, B. H., & Husain, M. I. (2020) · BJPsych Open · doi:10.1192/bjo.2020.43 · Cited by 106 · see citing works

Are there differences in lipid peroxidation and immune biomarkers between major depression and bipolar disorder: Effects of melancholia, atypical depression, severity of illness, episode number, suicidal ideation and prior suicide attempts

Sowa-Kućma, M., Styczeń, K., Siwek, M., Misztak, P., Nowak, R. J., Dudek, D., Rybakowski, J. K., Nowak, G., & Maes, M. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.08.024 · Cited by 104 · see citing works

Major Differences in Neurooxidative and Neuronitrosative Stress Pathways Between Major Depressive Disorder and Types I and II Bipolar Disorder

Maes, M., Landucci Bonifacio, K., Morelli, N. R., Vargas, H. O., Barbosa, D. S., Carvalho, A. F., & Nunes, S. O. V. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1051-7 · Cited by 102 · see citing works

Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches

Balmus, I. M., Ciobica, A., Antioch, I., Dobrin, R., & Timofte, D. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/3975101 · Cited by 103 · see citing works

A Review of Biomarkers in Mood and Psychotic Disorders: A Dissection of Clinical vs. Preclinical Correlates

Brand, S., Moller, M., & Harvey, B. (2015) · Current Neuropharmacology · doi:10.2174/1570159x13666150307004545 · Cited by 95 · see citing works

Coenzyme Q10 Depletion in Medical and Neuropsychiatric Disorders: Potential Repercussions and Therapeutic Implications

Morris, G., Anderson, G., Berk, M., & Maes, M. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8477-8 · Cited by 96 · see citing works

Towards recovery-oriented psychosocial interventions for bipolar disorder: Quality of life outcomes, stage-sensitive treatments, and mindfulness mechanisms

Murray, G., Leitan, N. D., Thomas, N., Michalak, E. E., Johnson, S. L., Jones, S., Perich, T., Berk, L., & Berk, M. (2017) · Clinical Psychology Review · doi:10.1016/j.cpr.2017.01.002 · Cited by 87 · see citing works

Lowered plasma paraoxonase (PON)1 activity is a trait marker of major depression and PON1 Q192R gene polymorphism–smoking interactions differentially predict the odds of major depression and bipolar disorder

Bortolasci, C. C., Vargas, H. O., Souza-Nogueira, A., Barbosa, D. S., Moreira, E. G., Nunes, S. O. V., Berk, M., Dodd, S., & Maes, M. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.02.018 · Cited by 83 · see citing works

Neutrophil-to-Lymphocyte Ratio, a Novel Inflammatory Marker, as a Predictor of Bipolar Type in Depressed Patients: A Quest for Biological Markers

Dionisie, V., Filip, G. A., Manea, M. C., Movileanu, R. C., Moisa, E., Manea, M., Riga, S., & Ciobanu, A. M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10091924 · Cited by 82 · see citing works

Rationale and First Results of Developing At-Risk (Prodromal) Criteria for Bipolar Disorder

Bechdolf, A., Ratheesh, A., J. Wood, S., Tecic, T., Conus, P., Nelson, B., M. Cotton, S., M. Chanen, A., P. Amminger, G., Ruhrmann, S., et al. (2012) · Current Pharmaceutical Design · doi:10.2174/138161212799316226 · Cited by 82 · see citing works

Smoking and the risk for bipolar disorder: evidence from a bidirectional Mendelian randomisation study

Vermeulen, J. M., Wootton, R. E., Treur, J. L., Sallis, H. M., Jones, H. J., Zammit, S., van den Brink, W., Goodwin, G. M., de Haan, L., & Munafò, M. R. (2021) · The British Journal of Psychiatry · doi:10.1192/bjp.2019.202 · Cited by 78 · see citing works

Systemic oxidatively generated DNA/RNA damage in clinical depression: associations to symptom severity and response to electroconvulsive therapy

Jorgensen, A., Krogh, J., Miskowiak, K., Bolwig, T. G., Kessing, L. V., Fink-Jensen, A., Nordentoft, M., Henriksen, T., Weimann, A., Poulsen, H. E., et al. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.02.011 · Cited by 74 · see citing works

Pop, heavy metal and the blues: secondary analysis of persistent organic pollutants (POP), heavy metals and depressive symptoms in the NHANES National Epidemiological Survey

Berk, M., Williams, L. J., Andreazza, A. C., Pasco, J. A., Dodd, S., Jacka, F. N., Moylan, S., Reiner, E. J., & Magalhaes, P. V. S. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-005142 · Cited by 77 · see citing works

Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression

Tang, M.-M., Lin, W.-J., Pan, Y.-Q., & Li, Y.-C. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00255 · Cited by 73 · see citing works

Longitudinal multi-level biomarker analysis of BDNF in major depression and bipolar disorder

Schröter, K., Brum, M., Brunkhorst-Kanaan, N., Tole, F., Ziegler, C., Domschke, K., Reif, A., & Kittel-Schneider, S. (2020) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-019-01007-y · Cited by 68 · see citing works

Interleukin-1 β-Targeted Treatment Strategies in Inflammatory Depression: Toward Personalized Care

Ellul, P., Boyer, L., Groc, L., Leboyer, M., & Fond, G. (2016) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12656 · Cited by 65 · see citing works

Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder

Pfaffenseller, B., Fries, G. R., Wollenhaupt-Aguiar, B., Colpo, G. D., Stertz, L., Panizzutti, B., Magalhães, P. V., & Kapczinski, F. (2013) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2013.811981 · Cited by 68 · see citing works

Associations of serum cytokine receptor levels with melancholia, staging of illness, depressive and manic phases, and severity of depression in bipolar disorder.

Siwek, M., Sowa-Kućma, M., Styczeń, K., Misztak, P., Nowak, R. J., Szewczyk, B., Dudek, D., Rybakowski, J. K., Nowak, G., & Maes, M. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-0124-8 · Cited by 65 · see citing works

Transcriptome sequencing implicates dorsal striatum-specific gene network, immune response and energy metabolism pathways in bipolar disorder

Pacifico, R., & Davis, R. L. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.94 · Cited by 61 · see citing works

Tobacco use in bipolar disorder

Thomson, D., Berk, M., Dodd, S., Rapado-Castro, M., Quirk, S. E., Ellegaard, P. K., Berk, L., & Dean, O. M. (2015) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2015.13.1.1 · Cited by 63 · see citing works

Bias in emerging biomarkers for bipolar disorder

Carvalho, A. F., Köhler, C. A., Fernandes, B. S., Quevedo, J., Miskowiak, K. W., Brunoni, A. R., Machado-Vieira, R., Maes, M., Vieta, E., & Berk, M. (2016) · Psychological Medicine · doi:10.1017/s0033291716000957 · Cited by 63 · see citing works

Neutrophil/Lymphocyte, Platelet/Lymphocyte, and Monocyte/Lymphocyte Ratios in Mood Disorders

Marazziti, D., Torrigiani, S., Carbone, M. G., Mucci, F., Flamini, W., Ivaldi, T., & Dell'Osso, L. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867328666210922160116 · Cited by 61 · see citing works

Protocol and rationale-the efficacy of minocycline as an adjunctive treatment for major depressive disorder: a double blind, randomised, placebo controlled trial

Dean, O. M., Maes, M., Ashton, M., Berk, L., Kanchanatawan, B., Sughondhabirom, A., Tangwongchai, S., Ng, C., Dowling, N., Malhi, G. S., et al. (2014) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2014.12.3.180 · Cited by 58 · see citing works

Effects of <scp>N</scp>‐acetyl cysteine on cognitive function in bipolar disorder

Dean, O. M., Bush, A. I., Copolov, D. L., Kohlmann, K., Jeavons, S., Schapkaitz, I., Anderson‐Hunt, M., & Berk, M. (2012) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2012.02392.x · Cited by 58 · see citing works

A preliminary investigation on the efficacy of <i>N</i> -acetyl cysteine for mania or hypomania

Vieira da Silva Magalhães, P., Dean, O. M., Bush, A. I., Copolov, D. L., Malhi, G. S., Kohlmann, K., Jeavons, S., Schapkaitz, I., Anderson-Hunt, M., & Berk, M. (2013) · Australian &amp; New Zealand Journal of Psychiatry · doi:10.1177/0004867413481631 · Cited by 58 · see citing works

Neuroprogression as an illness trajectory in bipolar disorder: a selective review of the current literature

Serafini, G., Pardini, M., Monacelli, F., Orso, B., Girtler, N., Brugnolo, A., Amore, M., Nobili, F., & Team on Dementia of the IRCCS Ospedale Policlinico San Martino (2021) · Brain Sciences · doi:10.3390/brainsci11020276 · Cited by 56 · see citing works

Evaluating the Effect of Coenzyme Q10 Augmentation on Treatment of Bipolar Depression: A Double-Blind Controlled Clinical Trial

Mehrpooya, M., Yasrebifar, F., Haghighi, M., Mohammadi, Y., & Jahangard, L. (2018) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000938 · Cited by 57 · see citing works

An application of the stress-diathesis model: A review about the association between smoking tobacco, smoking cessation, and mental health

Taylor, G. M. J., & Treur, J. L. (2023) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2022.100335 · Cited by 50 · see citing works

Subthreshold symptoms and time to relapse/recurrence in a community cohort of bipolar disorder outpatients

De Dios, C., Ezquiaga, E., Agud, J. L., Vieta, E., Soler, B., & García-López, A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.05.047 · Cited by 53 · see citing works

Inflammation as a unique marker of suicide ideation distinct from depression syndrome among U.S. adults

Bergmans, R. S., Kelly, K. M., & Mezuk, B. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.11.046 · Cited by 50 · see citing works

Cognitive effects of creatine monohydrate adjunctive therapy in patients with bipolar depression: Results from a randomized, double-blind, placebo-controlled trial

Toniolo, R. A., Fernandes, F. D. B. F., Silva, M., Dias, R. D. S., & Lafer, B. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.11.029 · Cited by 50 · see citing works

Systemic inflammation and grey matter volume in schizophrenia and bipolar disorder: moderation by childhood trauma severity.

Quidé, Y., Bortolasci, C. C., Spolding, B., Kidnapillai, S., Watkeys, O. J., Cohen-Woods, S., Carr, V. J., Berk, M., Walder, K., & Green, M. J. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110013 · Cited by 44 · see citing works

Enrichment pathway analysis. The inflammatory genetic background in Bipolar Disorder

Drago, A., Crisafulli, C., Calabrò, M., & Serretti, A. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.03.032 · Cited by 47 · see citing works

Blockade of the angiotensin system improves mental health domain of quality of life: A meta-analysis of randomized clinical trials

Brownstein, D. J., Salagre, E., Köhler, C., Stubbs, B., Vian, J., Pereira, C., Chavarria, V., Karmakar, C., Turner, A., Quevedo, J., et al. (2018) · Australian &amp; New Zealand Journal of Psychiatry · doi:10.1177/0004867417721654 · Cited by 46 · see citing works

Neurotrophic Factors and Their Receptors in Axonal Regeneration and Functional Recovery After Peripheral Nerve Injury

Boyd, J. G., & Gordon, T. (2003) · Molecular Neurobiology · doi:10.1385/mn:27:3:277 · Cited by 515 · see citing works

Neurotrophic factors in brain development

Ringstedt, T. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511711848.008 · Cited by 1 · see citing works

Quadriceps muscle strength, contractile properties, and motor unit firing rates in young and old men

Roos, M. R., Rice, C. L., Connelly, D. M., & Vandervoort, A. A. (1999) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(199908)22:8 · Cited by 269 · see citing works

Stimulation of neurotrophin synthesis by 4-methylcatechol: a promising approach for neuroprotection

Furukawa, S., Nitta, A., & Furukawa, Y. (1999) · Biomedical Reviews · doi:10.14748/bmr.v10.7 · Cited by 1 · see citing works

The neurotrophic hypothesis: where does it stand?

Davies, A. M. (1996) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1996.0033 · Cited by 151 · see citing works