EXERCISE AND SKELETAL MUSCLE GLUCOSE TRANSPORTER 4 EXPRESSION: MOLECULAR MECHANISMS

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

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Mitochondrial dysfunction and type 2 diabetes

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Transcriptional regulation by calcium, calcineurin, and NFAT

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

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Biochemical Adaptations in Muscle

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Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

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TRANSCRIPTIONAL CONTROL OF MUSCLE DEVELOPMENT BY MYOCYTE ENHANCER FACTOR-2 (MEF2) PROTEINS

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Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1

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Molecular cloning and characterization of an insulin-regulatable glucose transporter

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MEF2: a calcium-dependent regulator of cell division, differentiation and death

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Activation of PPARγ Coactivator-1 Through Transcription Factor Docking

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Dealing with energy demand: the AMP-activated protein kinase

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Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases

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Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

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Regulation of the MEF2 Family of Transcription Factors by p38

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Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5

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Control of muscle development by dueling HATs and HDACs

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Effect of Exercise Intensity on Skeletal Muscle AMPK Signaling in Humans

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Regeneration in the metazoans: why does it happen?

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Evidence Against Altered Expression of GLUT1 or GLUT4 in Skeletal Muscle of Patients With Obesity or NIDDM

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Crystal Structures of MAP Kinase p38 Complexed to the Docking Sites on Its Nuclear Substrate MEF2A and Activator MKK3b

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PGC-1, a versatile coactivator

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Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase

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Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor

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Physical Training Increases Muscle GLUT4 Protein and mRNA in Patients With NIDDM

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Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle

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Mechanism for Nucleocytoplasmic Shuttling of Histone Deacetylase 7

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Exercise and Myocyte Enhancer Factor 2 Regulation in Human Skeletal Muscle

McGee, S. L., & Hargreaves, M. (2004) · Diabetes · doi:10.2337/diabetes.53.5.1208 · Cited by 205

Mechanisms underlying the reduction of isometric force in skeletal muscle fatigue

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Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice

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Myocyte Enhancer Factor 2 (MEF2)-Binding Site Is Required forGLUT4 Gene Expression in Transgenic Mice

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Signaling chromatin to make muscle

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Exercise induces a transient increase in transcription of the GLUT-4 gene in skeletal muscle

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Mitogen‐activated protein kinase signal transduction in skeletal muscle: effects of exercise and muscle contraction

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Exercise Increases Ca2+–Calmodulin‐Dependent Protein Kinase II Activity in Human Skeletal Muscle

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Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice.

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Exercise Increases Nuclear AMPK α2 in Human Skeletal Muscle

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Effects of exercise on GLUT-4 and glycogenin gene expression in human skeletal muscle

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Site of enhanced insulin sensitivity in exercise-trained rats at rest

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Improvement of Insulin Action in Diabetic Transgenic Mice Selectively Overexpressing GLUT4 in Skeletal Muscle

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The MEF2A Isoform Is Required for Striated Muscle-specific Expression of the Insulin-responsive GLUT4 Glucose Transporter

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Regulation of the human GLUT4 gene promoter: Interaction between a transcriptional activator and myocyte enhancer factor 2A

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Exercise increases MEF2‐ and GEF DNA‐binding activities in human skeletal muscle

McGee, S. L., Sparling, D., Olson, A., & Hargreaves, M. (2006) · The FASEB Journal · doi:10.1096/fj.05-4671fje · Cited by 100

Identification of a 30-Base Pair Regulatory Element and Novel DNA Binding Protein That Regulates the Human GLUT4 Promoter in Transgenic Mice

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Ca2+ transients activate calcineurin/NFATc1 and initiate fast-to-slow transformation in a primary skeletal muscle culture

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Effect of fill-pulse parameters on deep-level transient spectroscopy peaks in highly doped p-type InP

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Exercise, GLUT4, and skeletal muscle glucose uptake

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Epigenetics: a molecular link between environmental factors and type 2 diabetes

Ling, C., & Groop, L. (2009) · Diabetes · doi:10.2337/db09-1003 · Cited by 617

Exercise, MAPK, and NF-κB signaling in skeletal muscle

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Epigenetics, DNA Methylation, and Chromatin Modifying Drugs

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Epigenomics, gestational programming and risk of metabolic syndrome

Desai, M., Jellyman, J. K., & Ross, M. G. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.13 · Cited by 289

Exercise and Myocyte Enhancer Factor 2 Regulation in Human Skeletal Muscle

McGee, S. L., & Hargreaves, M. (2004) · Diabetes · doi:10.2337/diabetes.53.5.1208 · Cited by 205

Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle. Diabetes 53: 1208–1214

Mcgee, S. L., & Hargreaves, M. (2004)

Regulation of GLUT4 Gene Expression during Exercise

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Mechanisms regulating GLUT4 glucose transporter expression and glucose transport in skeletal muscle

Antonio Zorzano, A., Palacín, M., & Gumà, A. (2005) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.2004.01380.x · Cited by 205

©2005 FASEB The FASEB Journal express article 10.1096/fj.05-4671fje. Published online December 20, 2005. Exercise increases MEF2- and GEF DNA-binding activities in human skeletal muscle

Mcgee, S. L., Sparling, D., Olson, A.-L., & Hargreaves, M. (2013)