Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

THE AMP-ACTIVATED/SNF1 PROTEIN KINASE SUBFAMILY: Metabolic Sensors of the Eukaryotic Cell?

Hardie, D. G., Carling, D., & Carlson, M. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.821 · Cited by 1,436 · see citing works

Exercise, Glucose Transport, and Insulin Sensitivity

Goodyear, L. J., & Kahn, B. B. (1998) · Annual Review of Medicine · doi:10.1146/annurev.med.49.1.235 · Cited by 1,056 · see citing works

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle

Merrill, G. F., Kurth, E. J., Hardie, D. G., & Winder, W. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.6.e1107 · Cited by 1,027 · see citing works

AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes

Winder, W. W., & Hardie, D. G. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.1.e1 · Cited by 1,000 · see citing works

d-Glucose

Slein, M. W. (1965) · Elsevier eBooks · doi:10.1016/b978-0-12-395630-9.50023-2 · Cited by 850 · see citing works

Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise

Winder, W. W., & Hardie, D. G. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.2.e299 · Cited by 799 · see citing works

Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport

Hayashi, T., Hirshman, M. F., Kurth, E. J., Winder, W. W., & Goodyear, L. J. (1998) · Diabetes · doi:10.2337/diab.47.8.1369 · Cited by 774 · see citing works

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

Kurth-Kraczek, E. J., Hirshman, M. F., Goodyear, L. J., & Winder, W. W. (1999) · Diabetes · doi:10.2337/diabetes.48.8.1667 · Cited by 715 · see citing works

[7] Chemical procedures for analysis of polysaccharides

Hassid, W. Z., & Abraham, S. (1957) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(57)03345-5 · Cited by 712 · see citing works

Malonyl-CoA, fuel sensing, and insulin resistance

Ruderman, N. B., Saha, A. K., Vavvas, D. G., & Witters, L. A. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.276.1.e1 · Cited by 644 · see citing works

Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance

Garvey, W. T., Maianu, L., Zhu, J. H., Brechtel-Hook, G., Wallace, P., & Baron, A. D. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1557 · Cited by 459 · see citing works

Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle.

Ren, J., Semenkovich, C. F., Gulve, E. A., Gao, J. H., & Holloszy, J. O. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36636-x · Cited by 416 · see citing works

Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes

Kennedy, J. W., Hirshman, M. F., Gervino, E. V., Ocel, J. V., Forse, R. A., Hoenig, S. J., Aronson, D., Goodyear, L. J., & Horton, E. S. (1999) · Diabetes · doi:10.2337/diabetes.48.5.1192 · Cited by 415 · see citing works

Exercise regulation of glucose transport in skeletal muscle.

Hayashi, T., Wojtaszewski, J., & Goodyear, L. (1997) · American Journal of Physiology · doi:10.1152/ajpendo.1997.273.6.e1039 · Cited by 394 · see citing works

Role of Exercise Training in the Prevention and Treatment of Insulin Resistance and Non-Insulin-Dependent Diabetes Mellitus

Ivy, J. L. (1997) · Sports Medicine · doi:10.2165/00007256-199724050-00004 · Cited by 366 · see citing works

Evidence Against Altered Expression of GLUT1 or GLUT4 in Skeletal Muscle of Patients With Obesity or NIDDM

Pedersen, O., Bak, J. F., Andersen, P. H., Lund, S., Moller, D. E., Flier, J. S., & Kahn, B. B. (1990) · Diabetes · doi:10.2337/diab.39.7.865 · Cited by 329 · see citing works

Regulatory Mechanisms in Carbohydrate Metabolism

Uyeda, K., & Racker, E. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)97009-2 · Cited by 309 · see citing works

Effect of AMPK activation on muscle glucose metabolism in conscious rats

Bergeron, R., Russell, R. R., Young, L. H., Ren, J., Marcucci, M., Lee, A., & Shulman, G. I. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.276.5.e938 · Cited by 301 · see citing works

Gene Expression of GLUT4 in Skeletal Muscle From Insulin-Resistant Patients With Obesity, IGT, GDM, and NIDDM

Garvey, W. T., Maianu, L., Hancock, J. A., Golichowski, A. M., & Baron, A. (1992) · Diabetes · doi:10.2337/diab.41.4.465 · Cited by 289 · see citing works

Physical Training Increases Muscle GLUT4 Protein and mRNA in Patients With NIDDM

Dela, F., Ploug, T., Handberg, A., Petersen, L. N., Larsen, J. J., Mikines, K. J., & Galbo, H. (1994) · Diabetes · doi:10.2337/diab.43.7.862 · Cited by 252 · see citing works

Regulatory Mechanisms in Carbohydrate Metabolism

Wu, R. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69674-7 · Cited by 229 · see citing works

The effect of non-insulin-dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle.

Kelley, D. E., Mintun, M. A., Watkins, S. C., Simoneau, J. A., Jadali, F., Fredrickson, A., Beattie, J., & Thériault, R. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118724 · Cited by 228 · see citing works

Exercise induces a transient increase in transcription of the GLUT-4 gene in skeletal muscle

Neufer, P. D., & Dohm, G. L. (1993) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1993.265.6.c1597 · Cited by 192 · see citing works

Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay.

McGarry, J., Stark, M. J., & Foster, D. W. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34394-6 · Cited by 188 · see citing works

Regulation of glucose transport into skeletal muscle

Holloszy, J. O., & Hansen, P. A. (1996) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/3-540-61343-9_8 · Cited by 151 · see citing works

Expression of insulin regulatable glucose transporters in skeletal muscle from Type 2 (non-insulin-dependent) diabetic patients

Handberg, A., Vaag, A. A., Damsbo, P., Beck‐Nielsen, H., & Vinten, J. (1990) · Diabetologia · doi:10.1007/bf00400207 · Cited by 150 · see citing works

Exercise in the Management of Non???Insulin-Dependent Diabetes Mellitus

Wallberg‐Henriksson, H., Rincón, J., & Zierath, J. R. (1998) · Sports Medicine · doi:10.2165/00007256-199825010-00003 · Cited by 127 · see citing works

Rapid reversal of adaptive increases in muscle GLUT-4 and glucose transport capacity after training cessation

Host, H. H., Hansen, P. A., Nolte, L. A., Chen, M. M., & Holloszy, J. O. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.84.3.798 · Cited by 100 · see citing works

Hypoglycaemic effect of AICAriboside in mice

Vincent, M. F., Erion, M. D., Gruber, H. E., & den Berghe, G. V. (1996) · Diabetologia · doi:10.1007/bf02658500 · Cited by 93 · see citing works

Exercise training reverses insulin resistance in muscle by enhanced recruitment of GLUT-4 to the cell surface

Etgen, G. J., Jensen, J., Wilson, C. M., Hunt, D. G., Cushman, S. W., & Ivy, J. L. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.5.e864 · Cited by 88 · see citing works

Effect of 7-10 days of cycle ergometer exercise on skeletal muscle GLUT-4 protein content

Gulve, E. A., & Spina, R. J. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.79.5.1562 · Cited by 77 · see citing works

Regulatory Elements in the Insulin-Responsive Glucose Transporter (GLUT4) Gene

Ezaki, O. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7587 · Cited by 71 · see citing works

Glycogen supercompensation masks the effect of a traininginduced increase in GLUT-4 on muscle glucose transport

Host, H. H., Hansen, P. A., Nolte, L. A., Chen, M. M., & Holloszy, J. O. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.1.133 · Cited by 52 · see citing works

Effect of Long-Term Exercise on Gene Expression of Insulin Signaling Pathway Intermediates in Skeletal Muscle

Kim, Y., Inoue, T., Nakajima, R., Shirai-Morishita, Y., Tokuyama, K., & Suzuki, M. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9940 · Cited by 49 · see citing works

Regulated Expression of 5′-Deleted Mouse GLUT4 Minigenes in Transgenic Mice: Effects of Exercise Training and High-Fat Diet

Tsunoda, N., Cooke, D. W., Ikemoto, S., et al. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7516 · Cited by 26 · see citing works

Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action

Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13505 · Cited by 5,652 · see citing works

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Jäger, S., Handschin, C., St.-Pierre, J., & Spiegelman, B. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705070104 · Cited by 2,491 · see citing works

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

Hardie, D. G. (2011) · Genes & Development · doi:10.1101/gad.17420111 · Cited by 1,638 · see citing works

Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1

Baar, K., Wende, A. R., Jones, T. E., Marison, M., Nolte, L. A., Chen, M., Kelly, D. P., & Holloszy, J. O. (2002) · The FASEB Journal · doi:10.1096/fj.02-0367com · Cited by 1,020 · see citing works

A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle

Mu, J., Brozinick, J. T., Valladares, O., Bucan, M., & Birnbaum, M. J. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00251-9 · Cited by 924 · see citing works

AMP-Activated Protein Kinase – Development of the Energy Sensor Concept

Hardie, D. G., Hawley, S. A., & Scott, J. W. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.108944 · Cited by 813 · see citing works

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

Musi, N., Hirshman, M. F., Nygren, J., Svanfeldt, M., Bavenholm, P., Rooyackers, O., Zhou, G., Williamson, J. M., Ljunqvist, O., Efendic, S., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2074 · Cited by 806 · see citing works

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

Russell, R. R., Li, J., Coven, D. L., Pypaert, M., Zechner, C., Palmeri, M., Giordano, F. J., Mu, J., Birnbaum, M. J., & Young, L. H. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19297 · Cited by 738 · see citing works

Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle

Winder, W. W., Holmes, B. F., Rubink, D. S., Jensen, E. B., Chen, M., & Holloszy, J. O. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.6.2219 · Cited by 709 · see citing works

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

Um, J.-H., Park, S.-J., Kang, H., Yang, S., Foretz, M., McBurney, M. W., Kim, M. K., Viollet, B., & Chung, J. H. (2010) · Diabetes · doi:10.2337/db09-0482 · Cited by 647 · see citing works

Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis

Reznick, R. M., Zong, H., Li, J., Morino, K., Moore, I. K., Yu, H. J., Liu, Z.-X., Dong, J., Mustard, K. J., Hawley, S. A., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.01.008 · Cited by 555 · see citing works

Knockout of the α2 but Not α1 5′-AMP-activated Protein Kinase Isoform Abolishes 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranosidebut Not Contraction-induced Glucose Uptake in Skeletal Muscle

Jørgensen, S. B., Viollet, B., Andreelli, F., Frøsig, C., Birk, J. B., Schjerling, P., Vaulont, S., Richter, E. A., & Wojtaszewski, J. F. P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m306205200 · Cited by 553 · see citing works

AMPK and the biochemistry of exercise: implications for human health and disease

Richter, E. A., & Ruderman, N. B. (2009) · Biochemical Journal · doi:10.1042/bj20082055 · Cited by 481 · see citing works

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

McGee, S. L., van Denderen, B. J. W., Howlett, K. F., Mollica, J., Schertzer, J. D., Kemp, B. E., & Hargreaves, M. (2008) · Diabetes · doi:10.2337/db07-0843 · Cited by 455 · see citing works

AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise

Musi, N., Fujii, N., Hirshman, M. F., Ekberg, I., Fröberg, S., Ljungqvist, O., Thorell, A., & Goodyear, L. J. (2001) · Diabetes · doi:10.2337/diabetes.50.5.921 · Cited by 371 · see citing works

Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle

Fujii, N., Hayashi, T., Hirshman, M. F., Smith, J. T., Habinowski, S. A., Kaijser, L., Mu, J., Ljungqvist, O., Birnbaum, M. J., Witters, L. A., et al. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3073 · Cited by 351 · see citing works

Creatine: Endogenous Metabolite, Dietary, and Therapeutic Supplement

Brosnan, J. T., & Brosnan, M. E. (2007) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.27.061406.093621 · Cited by 347 · see citing works

Adaptations of Skeletal Muscle to Prolonged, Intense Endurance Training

Hawley, J. A. (2002) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2002.03623.x · Cited by 328 · see citing works

Periodized Nutrition for Athletes

Jeukendrup, A. E. (2017) · Sports Medicine · doi:10.1007/s40279-017-0694-2 · Cited by 299 · see citing works

Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice

Li, B., Nolte, L. A., Ju, J.-S., Ho Han, D., Coleman, T., Holloszy, J. O., & Semenkovich, C. F. (2000) · Nature Medicine · doi:10.1038/80450 · Cited by 291 · see citing works

AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats

Iglesias, M. A., Ye, J.-M., Frangioudakis, G., Saha, A. K., Tomas, E., Ruderman, N. B., Cooney, G. J., & Kraegen, E. W. (2002) · Diabetes · doi:10.2337/diabetes.51.10.2886 · Cited by 290 · see citing works

<scp>AMP</scp> ‐activated protein kinase: a key regulator of energy balance with many roles in human disease

Grahame Hardie, D. (2014) · Journal of Internal Medicine · doi:10.1111/joim.12268 · Cited by 285 · see citing works

Effects of α‐AMPK knockout on exercise‐induced gene activation in mouse skeletal muscle

Jørgensen, S. B., Wojtaszewski, J. F. P., Viollet, B., Andreelli, F., Birk, J. B., Hellsten, Y., Schjerling, P., Vaulont, S., Neufer, P. D., Richter, E. A., et al. (2005) · The FASEB Journal · doi:10.1096/fj.04-3144fje · Cited by 274 · see citing works

AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels

Hardie, D. G. (2014) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071812-161148 · Cited by 281 · see citing works

Glycogen-Dependent Effects of 5-Aminoimidazole-4-Carboxamide (AICA)-Riboside on AMP-Activated Protein Kinase and Glycogen Synthase Activities in RatSkeletal Muscle

Wojtaszewski, J. F. P., Jørgensen, S. B., Hellsten, Y., Hardie, D. G., & Richter, E. A. (2002) · Diabetes · doi:10.2337/diabetes.51.2.284 · Cited by 261 · see citing works

Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise

Jørgensen, S. B., Richter, E. A., & Wojtaszewski, J. F. P. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.109942 · Cited by 261 · see citing works

Treatment strategies against diabetes: Success so far and challenges ahead.

Khursheed, R., Singh, S. K., Wadhwa, S., Kapoor, B., Gulati, M., Kumar, R., Ramanunny, A. K., Awasthi, A., & Dua, K. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172625 · Cited by 239 · see citing works

Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise

Röckl, K. S. C., Witczak, C. A., & Goodyear, L. J. (2008) · IUBMB Life · doi:10.1002/iub.21 · Cited by 222 · see citing works

Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy

Brault, J. J., Jespersen, J. G., & Goldberg, A. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.113092 · Cited by 217 · see citing works

Metformin increases the PGC-1α protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo

Suwa, M., Egashira, T., Nakano, H., Sasaki, H., & Kumagai, S. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00255.2006 · Cited by 210 · see citing works

AMP-activated protein kinase: Also regulated by ADP?

Hardie, D. G., Carling, D., & Gamblin, S. J. (2011) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2011.06.004 · Cited by 187 · see citing works

5′AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes

Wojtaszewski, J. F. P., Birk, J. B., Frøsig, C., Holten, M., Pilegaard, H., & Dela, F. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.082669 · Cited by 170 · see citing works

AMP-activated protein kinase: a key system mediating metabolic responses to exercise

HARDIE, D. G. (2004) · Medicine &amp; Science in Sports &amp; Exercise · doi:10.1249/01.mss.0000106171.38299.64 · Cited by 165 · see citing works

Effect of Oral Creatine Supplementation on Human Muscle GLUT4 Protein Content After Immobilization

Eijnde, B. O. '., Ursø, B., Richter, E. A., Greenhaff, P. L., & Hespel, P. (2001) · Diabetes · doi:10.2337/diabetes.50.1.18 · Cited by 162 · see citing works

5′-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle

Frøsig, C., Jørgensen, S. B., Hardie, D. G., Richter, E. A., & Wojtaszewski, J. F. P. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00317.2003 · Cited by 161 · see citing works

Exercise Increases Nuclear AMPK α2 in Human Skeletal Muscle

McGee, S. L., Howlett, K. F., Starkie, R. L., Cameron-Smith, D., Kemp, B. E., & Hargreaves, M. (2003) · Diabetes · doi:10.2337/diabetes.52.4.926 · Cited by 160 · see citing works

AMPK activation attenuates S6K1, 4E-BP1, and eEF2 signaling responses to high-frequency electrically stimulated skeletal muscle contractions

Thomson, D. M., Fick, C. A., & Gordon, S. E. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00915.2007 · Cited by 153 · see citing works

Molecular Mechanism by Which AMP-Activated Protein Kinase Activation Promotes Glycogen Accumulation in Muscle

Hunter, R. W., Treebak, J. T., Wojtaszewski, J. F. P., & Sakamoto, K. (2011) · Diabetes · doi:10.2337/db10-1148 · Cited by 151 · see citing works

Skeletal muscle and heart LKB1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice.

Thomson, D. M., Porter, B. B., Tall, J. H., Kim, H.-J., Barrow, J. R., & Winder, W. W. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00366.2006 · Cited by 146 · see citing works

Exercise-induced AMPK activity in skeletal muscle: Role in glucose uptake and insulin sensitivity

Friedrichsen, M., Mortensen, B., Pehmøller, C., Birk, J. B., & Wojtaszewski, J. F. P. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.06.013 · Cited by 143 · see citing works

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2

Gan, Z., Burkart-Hartman, E. M., Han, D.-H., Finck, B., Leone, T. C., Smith, E. Y., Ayala, J. E., Holloszy, J., & Kelly, D. P. (2011) · Genes &amp; Development · doi:10.1101/gad.178434.111 · Cited by 138 · see citing works

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., et al. (2012) · Biochemical Journal · doi:10.1042/bj20112026 · Cited by 131 · see citing works

Exercise and skeletal muscle glucose transporter 4 expression: Molecular mechanisms

McGee, S. L., & Hargreaves, M. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04362.x · Cited by 126 · see citing works

Carbohydrate Availability and Training Adaptation: Effects on Cell Metabolism

Hawley, J. A., & Burke, L. M. (2010) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e3181f44dd9 · Cited by 109 · see citing works

The Exercise Pill — Too Good to Be True?

Goodyear, L. J. (2008) · New England Journal of Medicine · doi:10.1056/nejmcibr0806723 · Cited by 108 · see citing works

Ablation of AMP-Activated Protein Kinase α2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice

Fujii, N., Ho, R. C., Manabe, Y., Jessen, N., Toyoda, T., Holland, W. L., Summers, S. A., Hirshman, M. F., & Goodyear, L. J. (2008) · Diabetes · doi:10.2337/db07-1187 · Cited by 107 · see citing works

Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle

Steinberg, G. R., Watt, M. J., McGee, S. L., Chan, S., Hargreaves, M., Febbraio, M. A., Stapleton, D., & Kemp, B. E. (2006) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h06-003 · Cited by 104 · see citing works

Oral creatine supplementation and skeletal muscle metabolism in physical exercise

Mesa, J. L. M., Ruiz, J. R., Gonz??lez-Gross, M. M., Guti??rrez S??inz, ?., & Castillo Garz??n, M. J. (2002) · Sports Medicine · doi:10.2165/00007256-200232140-00003 · Cited by 103 · see citing works

Exercise increases MEF2‐ and GEF DNA‐binding activities in human skeletal muscle

McGee, S. L., Sparling, D., Olson, A., & Hargreaves, M. (2006) · The FASEB Journal · doi:10.1096/fj.05-4671fje · Cited by 100 · see citing works

Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise

Garcia-Roves, P. M., Han, D.-H., Song, Z., Jones, T. E., Hucker, K. A., & Holloszy, J. O. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00216.2003 · Cited by 93 · see citing works

Hypothalamic AMP-Activated Protein Kinase Regulates Glucose Production

Yang, C. S., Lam, C. K. L., Chari, M., Cheung, G. W. C., Kokorovic, A., Gao, S., Leclerc, I., Rutter, G. A., & Lam, T. K. T. (2010) · Diabetes · doi:10.2337/db10-0221 · Cited by 86 · see citing works

AMPK activation increases uncoupling protein-3 expression and mitochondrial enzyme activities in rat muscle without fibre type transitions

Putman, C. T., Kiricsi, M., Pearcey, J., MacLean, I. M., Bamford, J. A., Murdoch, G. K., Dixon, W. T., & Pette, D. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.040691 · Cited by 110 · see citing works

LKB1 and AMPK and the regulation of skeletal muscle metabolism

Koh, H.-J., Brandauer, J., & Goodyear, L. J. (2008) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e3282fb7b76 · Cited by 78 · see citing works

Chronic elevated calcium blocks AMPK-induced GLUT-4 expression in skeletal muscle

Park, S., Scheffler, T. L., Gunawan, A. M., Shi, H., Zeng, C., Hannon, K. M., Grant, A. L., & Gerrard, D. E. (2009) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00114.2008 · Cited by 76 · see citing works

Effect of acute activation of 5′-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscle

Miyamoto, L., Toyoda, T., Hayashi, T., Yonemitsu, S., Nakano, M., Tanaka, S., Ebihara, K., Masuzaki, H., Hosoda, K., Ogawa, Y., et al. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01034.2006 · Cited by 72 · see citing works

Deficiency of the Mitochondrial Electron Transport Chain in Muscle Does Not Cause Insulin Resistance

Han, D.-H., Hancock, C. R., Jung, S. R., Higashida, K., Kim, S. H., & Holloszy, J. O. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019739 · Cited by 71 · see citing works

Cloning and characterization of mouse 5′-AMP-activated protein kinase γ3 subunit

Yu, H., Fujii, N., Hirshman, M. F., Pomerleau, J. M., & Goodyear, L. J. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00319.2003 · Cited by 67 · see citing works

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Jeukendrup, A. E., & McLaughlin, J. (2011) · Nestlé Nutrition Institute Workshop Series · doi:10.1159/000329268 · Cited by 46 · see citing works

Sensing and responding to energetic stress: Evolution of the AMPK network

Craig, P. M., Moyes, C. D., & LeMoine, C. M. R. (2018) · Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2017.11.001 · Cited by 46 · see citing works

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Gray, S. G., McGuire, T. M., Cohen, N., & Little, P. J. (2017) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12893 · Cited by 40 · see citing works

Increases in glycogenin and glycogenin mRNA accompany glycogen resynthesis in human skeletal muscle

Shearer, J., Wilson, R. J., Battram, D. S., Richter, E. A., Robinson, D. L., Bakovic, M., & Graham, T. E. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00100.2005 · Cited by 32 · see citing works

Biological mechanisms of stroke prevention by physical activity in type 2 diabetes

Agosti, V., Graziano, S., Artiaco, L., & Sorrentino, G. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2008.01080.x · Cited by 25 · see citing works

Does impaired mitochondrial function affect insulin signaling and action in cultured human skeletal muscle cells?

Brown, A. E., Elstner, M., Yeaman, S. J., Turnbull, D. M., & Walker, M. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00267.2007 · Cited by 8 · see citing works

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AMP‐activated protein kinase and muscle glucose uptake

Musi, N., & Goodyear, L. J. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01168.x · Cited by 145 · see citing works

Rosiglitazone Treatment Enhances Acute AMP-Activated Protein Kinase–Mediated Muscle and Adipose Tissue Glucose Uptake in High-Fat–Fed Rats

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Glabridin induces glucose uptake via the AMP-activated protein kinase pathway in muscle cells

Sawada, K., Yamashita, Y., Zhang, T., Nakagawa, K., & Ashida, H. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.06.009 · Cited by 36 · see citing works

Regulation of nutrient uptake by AMP-activated protein kinase

Alghamdi, F. B., Alshuweishi, Y., & Salt, I. P. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2020.109807 · Cited by 17 · see citing works