The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Enhanced affective brain representations of chocolate in cravers vs. non‐cravers
Abstract
To examine the neural circuitry involved in food craving, in making food particularly appetitive and thus in driving wanting and eating, we used fMRI to measure the response to the flavour of chocolate, the sight of chocolate and their combination in cravers vs. non‐cravers. Statistical parametric mapping (SPM) analyses showed that the sight of chocolate produced more activation in chocolate cravers than non‐cravers in the medial orbitofrontal cortex and ventral striatum. For cravers vs. non‐cravers, a combination of a picture of chocolate with chocolate in the mouth produced a greater effect than the sum of the components (i.e. supralinearity) in the medial orbitofrontal cortex and pregenual cingulate cortex. Furthermore, the pleasantness ratings of the chocolate and chocolate‐related stimuli had higher positive correlations with the fMRI blood oxygenation level‐dependent signals in the pregenual cingulate cortex and medial orbitofrontal cortex in the cravers than in the non‐cravers. To our knowledge, this is the first study to show that there are differences between cravers and non‐cravers in their responses to the sensory components of a craved food in the orbitofrontal cortex, ventral striatum and pregenual cingulate cortex, and that in some of these regions the differences are related to the subjective pleasantness of the craved foods. Understanding individual differences in brain responses to very pleasant foods helps in the understanding of the mechanisms that drive the liking for specific foods and thus intake of those foods.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The OFC is also involved in attributing salience value to food (115,116), helping to assess its expected pleasantness and palatability as a function of its context.”
From Obesity and addiction: Neurobiological overlaps (2013) · cites this paper as [115]
In the citing paper
“Predictably, the OFC has also been implicated in attributing salience value to food (Grabenhorst et al 2008;Rolls and McCabe 2007), helping to assess its expected pleasantness and palatability as a function of its context.”
From Food and Drug Reward: Overlapping Circuits in Human Obesity and Addiction (2011) · cites this paper as Rolls and McCabe 2007
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space
Collins, D. L., Neelin, P., Peters, T. M., & Evans, A. C. (1994) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199403000-00005 · Cited by 3,431 · cited 2×
“…of the data used SPM2 realignment, reslicing with sinc interpolation, normalization to the Montreal Neurological Institute coordinate system (Collins et al., 1994) used throughout this study, and spatial smoothing with a 8 mm full width at half maximum isotropic Gaussian kernel and global…”
MethodOngur, D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.206 · Cited by 2,627
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex
Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00007-6 · Cited by 2,129
KRINGELBACH, M. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.006 · Cited by 1,977
Assessing the significance of focal activations using their spatial extent
Friston, K. J., Worsley, K. J., Frackowiak, R. S. J., Mazziotta, J. C., & Evans, A. C. (1994) · Human Brain Mapping · doi:10.1002/hbm.460010306 · Cited by 1,907
Berridge, K. C., & Robinson, T. E. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00233-9 · Cited by 1,869
Analysis of functional MRI time‐series
Friston, K. J., Jezzard, P., & Turner, R. (1994) · Human Brain Mapping · doi:10.1002/hbm.460010207 · Cited by 1,835
Neurobehavioural mechanisms of reward and motivation
Robbins, T. W., & Everitt, B. J. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80077-8 · Cited by 1,187
Changes in brain activity related to eating chocolate: From pleasure to aversion
Small, D. M. (2001) · Brain · doi:10.1093/brain/124.9.1720 · Cited by 1,179 · cited 4×
“Previous investigations in which brain responses to chocolate were measured did not include a comparison between cravers and noncravers (Small et al., 2001; Kringelbach et al., 2003), and indeed we”
BackgroundInfluentialNeural responses during anticipation of a primary taste reward
O'Doherty, J. P., Deichmann, R., Critchley, H. D., & Dolan, R. J. (2002) · Neuron · doi:10.1016/s0896-6273(02)00603-7 · Cited by 1,076
Research works printed but not linked: 1
- 10.1093/cercor/bhm1097 · DOI
Cited by
Sorted by citations
Sescousse, G., Caldú, X., Segura, B., & Dreher, J.-C. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.002 · Cited by 782
The orbitofrontal cortex and beyond: From affect to decision-making
Rolls, E. T., & Fabian Grabenhorst, B. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.09.001 · Cited by 851
Self-citationObesity and addiction: Neurobiological overlaps
Volkow, N. D., Wang, G. ‐., Tomasi, D., & Baler, R. D. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01031.x · Cited by 800
Informatic parcellation of the network involved in the computation of subjective value
Clithero, J. A., & Rangel, A. (2014) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst106 · Cited by 706
Branding the brain: A critical review and outlook
Plaßmann, H., Ramsøy, T. Z., & Milosavljevic, M. (2012) · Journal of Consumer Psychology · doi:10.1016/j.jcps.2011.11.010 · Cited by 687
Metadata
- Authors
- Rolls, E. T., & McCabe, C.
- Affiliations
- University of Oxford (GB)
- Corresponding author
- Rolls, Edmund T.
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2007-08
- Volume
- 26
- Issue
- 4
- Pages
- 1067-1076
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W1599849466
- Cited by
- 188
- References
- 56
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 2 · 2023: 7 · 2022: 8 · 2021: 4 · 2020: 5 · 2019: 7 · 2018: 3 · 2017: 7 · 2016: 15 · 2015: 13 · 2014: 14 · 2013: 14 · 2012: 22
- FWCI
- 5.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- food cravings, chocolate, medial orbitofrontal cortex, ventral striatum, food pleasantness, supralinearity, sensory integration, individual differences, food liking
- MeSH terms
- Adult, Affect, Appetite, Brain, Brain Mapping, Cacao, Cues, Data Interpretation, Statistical, Eating, Female, Food Preferences, Humans, Individuality, Magnetic Resonance Imaging, Male, Photic Stimulation, Surveys and Questionnaires, Taste
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
