The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Microreview: Type IV secretion systems: versatility and diversity in function: Diversity and versatility of the type IV secretion system
Open accessAbstract
Type IV secretion systems (T4SSs) are large protein complexes which traverse the cell envelope of many bacteria. They contain a channel through which proteins or protein-DNA complexes can be translocated. This translocation is driven by a number of cytoplasmic ATPases which might energize large conformational changes in the translocation complex. The family of T4SSs is very versatile, shown by the great variety of functions among family members. Some T4SSs are used by pathogenic Gram-negative bacteria to translocate a wide variety of virulence factors into the host cell. Other T4SSs are utilized to mediate horizontal gene transfer, an event that greatly facilitates the adaptation to environmental changes and is the basis for the spread of antibiotic resistance among bacteria. Here we review the recent advances in the characterization of the architecture and mechanism of substrate transfer in a few representative T4SSs with a particular focus on their diversity of structure and function.
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Cites
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The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase
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Metadata
- Authors
- Wallden, K., Rivera-Calzada, A., & Waksman, G.
- Venue
- Cellular Microbiology
- Publisher
- Hindawi Limited
- Published
- 2010-07-20
- Volume
- 12
- Issue
- 9
- Pages
- 1203-1212
- ISSN
- 1462-5814 (ISSN-L)
- OpenAlex
- W2144626747
- Cited by
- 344
- References
- 48
- FWCI
- 8.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Wallden, K., Rivera-Calzada, A., & Waksman, G. (2010). Microreview: Type IV secretion systems: versatility and diversity in function: Diversity and versatility of the type IV secretion system. Cellular Microbiology. https://doi.org/10.1111/j.1462-5822.2010.01499.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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