The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Definition of a Bacterial Type IV Secretion Pathway for a DNA Substrate
Open accessAbstract
Bacteria use conjugation systems, a subfamily of the type IV secretion systems, to transfer DNA to recipient cells. Despite 50 years of research, the architecture and mechanism of action of the channel mediating DNA transfer across the bacterial cell envelope remains obscure. By use of a sensitive, quantifiable assay termed transfer DNA immunoprecipitation (TrIP), we identify contacts between a DNA substrate (T-DNA) and 6 of 12 components of the VirB/D4 conjugation system of the phytopathogen Agrobacterium tumefaciens . Our results define the translocation pathway for a DNA substrate through a bacterial conjugation machine, specifying the contributions of each subunit of the secretory apparatus to substrate passage.
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Cites
Agrobacterium -Mediated Plant Transformation: the Biology behind the “Gene-Jockeying” Tool
Gelvin, S. B. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.1.16-37.2003 · Cited by 1,379
The versatile bacterial type IV secretion systems
Cascales, E., & Christie, P. J. (2003) · Nature Reviews Microbiology · doi:10.1038/nrmicro753 · Cited by 694
Self-citationKuo, M.-H., & Allis, C. D. (1999) · Methods · doi:10.1006/meth.1999.0879 · Cited by 602
F factor conjugation is a true type IV secretion system
Lawley, T. D., Klimke, W. A., Gubbins, M. J., & Frost, L. S. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(03)00430-0 · Cited by 426
Bacterial conjugation: a two‐step mechanism for DNA transport
Llosa, M., Gomis‐Rüth, F. X., Coll, M., & Cruz, F. D. L. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03014.x · Cited by 400
The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase
Gomis-Rüth, F. X., Moncalián, G., Pérez-Luque, R., González, A., Cabezón, E., de la Cruz, F., & Coll, M. (2001) · Nature · doi:10.1038/35054586 · Cited by 339
Yeo, H.-J., Savvides, S. N., Herr, A. B., Lanka, E., & Waksman, G. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00142-8 · Cited by 217
VirB11 ATPases are dynamic hexameric assemblies: new insights into bacterial type IV secretion
Savvides, S. N. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg223 · Cited by 175
Llosa, M., Zunzunegui, S., & de la Cruz, F. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1830264100 · Cited by 150
Ward, D. V., Draper, O., Zupan, J. R., & Zambryski, P. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172390299 · Cited by 144
Cited by
Secretion systems in Gram-negative bacteria: Structural and mechanistic insights
Costa, T. R. D., Felisberto-Rodrigues, C., Meir, A., Prevost, M. S., Redzej, A., Trokter, M., & Waksman, G. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3456 · Cited by 1,132
Biological Diversity of Prokaryotic Type IV Secretion Systems
Alvarez-Martinez, C. E., & Christie, P. J. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00023-09 · Cited by 729
Self-citationBIOGENESIS, ARCHITECTURE, AND FUNCTION OF BACTERIAL TYPE IV SECRETION SYSTEMS
Christie, P. J., Atmakuri, K., Krishnamoorthy, V., Jakubowski, S., & Cascales, E. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.58.030603.123630 · Cited by 630
Self-citationFouts, D. E., Mongodin, E. F., Mandrell, R. E., Miller, W. G., Rasko, D. A., Ravel, J., Brinkac, L. M., DeBoy, R. T., Parker, C. T., Daugherty, S. C., et al. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030015 · Cited by 542
Brencic, A., & Winans, S. C. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.1.155-194.2005 · Cited by 434
Metadata
- Authors
- Cascales, E., & Christie, P. J.
- Venue
- Science
- Published
- 2004-05-21
- Volume
- 304
- Issue
- 5674
- Pages
- 1170-1173
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2100740117
- Cited by
- 353
- References
- 15
- FWCI
- 14.82
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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