Cited by 33Substance Abuse Treatment and OutcomesAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and Access

Some new directions for research on psychological interventions for comorbid anxiety and substance use disorders

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BAILLIE, ANDREW J., STAPINSKI, LEXINE, CROME, ERICA, MORLEY, KIRSTEN, SANNIBALE, CLAUDIA, HABER, PAUL, TEESSON, MAREE·2010·Drug and Alcohol Review

Abstract

Abstract Issues. Comorbidity between anxiety and substance use disorders is common, yet it is poorly understood and poorly treated. Approach. Narrative literature review. PsycINFO and Medline databases were searched for clinical trials of anxiety and substance use disorders using clinical queries for 2005–2009. Key Findings. There are few well‐conducted treatment outcome trials for comorbid anxiety and substance use disorders. Some recent (2005–2009) outcome literature has focused on specific mechanisms (anxiety sensitivity and tension reduction alcohol expectancies) that may underlie comorbidity between anxiety and substance use disorders and may lead to more targeted intervention. Implications and Conclusion: The research base for understanding and treating comorbid anxiety and substance use disorders needs to be broadened. In particular research is needed with a focus on: (i) specifying particular comorbid relationships between anxiety and substance use disorders; (ii) the mechanisms that may underlie and maintain those relationships; and (iii) well‐conducted evaluations of treatments that target those mechanisms.[Baillie AJ, Stapinski L, Crome E, Morley K, Sannibale C, Haber P, Teesson M. Some new directions for research on psychological interventions for comorbid anxiety and substance use disorders. Drug Alcohol Rev 2010;29;518–524]

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  • Given the feed-forward cycle between alcohol use and anxiety, it is possible that combining these programs will have multiplicative effects on treatment outcomes.

    “Given the feed-forward cycle between alcohol use and anxiety, whereby each disorder fuels and impedes recovery from the other (Baillie et al., 2010; Stewart and Conrod, 2008), it is possible that combining these programs will have multiplicative effects on treatment outcomes.”

    From Acceptability and Co-Development of an Online Cognitive Bias Modification Intervention for Emerging Adults With Hazardous Alcohol Use and Social Anxiety: A Mixed Methods Study (2020) · cites this paper as Baillie et al., 2010

    The Conclusions and suggestions for future research (page not available) say that relationships between some comorbid disorders appear at least partially reciprocal, supporting the idea of a possible cycle. The Prediction of outcome in clinical samples section says comorbid anxiety predicts worse alcohol-treatment outcomes in some studies but not others; it does not establish that each disorder impedes recovery from the other. The proposed multiplicative effect follows the citation and is the citing authors’ speculation, not a finding attributed to this source. (LLM, conf=0.84)

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  • When alcohol use and anxiety disorders co-occur, ongoing interactions between the disorders may maintain or exacerbate each other in a vicious perpetuating cycle.

    “When alcohol use and anxiety disorders co-occur, there are ongoing interactions between the disorders that may maintain or exacerbate each other in a vicious perpetuating cycle (Baillie et al., 2010; Stewart and Conrod, 2008).”

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Research works printed but not linked: 45

  1. Morris EP, Stewart SH, Ham LS. The relationship between social anxiety disorder and alcohol use disorders: a critical review. Clin Psychol Rev 2005;25:734-60.
  2. Merikangas KR, Mehta RL, Molnar BE, et al. Comorbidity of substance use disorders with mood and anxiety disor- ders: results of the international consortium in psychiatric epidemiology. Addict Behav 1998;23:893-907.
  3. Oei TPS, Loveday WA. Management of co-morbid anxiety and alcohol disorders: parallel treatment of disorders. Drug Alcohol Rev 1997;16:261-74.
  4. Schade A, Marquenie L, van Balkom A, et al. The effective- ness of anxiety treatment on alcohol-dependent patients with a comorbid phobic disorder: a randomized controlled trial. Alcohol Clin Exp Res 2005;29:794-800.
  5. Randall C, Thomas S, Thevos A. Concurrent alcoholism and social anxiety disorder: a first step toward developing effective treatments. Alcohol Clin Exp Res 2001;25:210- 20.
  6. Neale MC, Kendler KS. Models of comorbidity for multi- factorial disorders. Am J Hum Genet 1995;57:935-53.
  7. Hall W, Degenhardt L, Teesson M. Understanding comor- bidity between substance use, anxiety and affective disor- ders: broadening the research base. Addict Behav 2009;34:526-30.
  8. Kendler KS. Introduction to a proposal for a meta-structure for DSM-V and ICD-11. Psychol Med 2009;39:1991.
  9. Krueger RF, Markon KE. Reinterpreting comorbidity: a model-based approach to understanding and classifying psychopathology. Annu Rev Clin Psychol 2006;2:111- 33.
  10. Schuckit MA, Hesselbrock V. Alcohol dependence and anxiety disorders: what is the relationship? Am J Psychiatry 1994;151:1723-34.
  11. Sclafani VD, Finn P, Fein G. Psychiatric comorbidity in long-term abstinent alcoholic individuals. Alcohol Clin Exp Res 2007;31:795-803.
  12. Haslam N. Categorical versus dimensional models of mental disorder: the taxometric evidence. Aust N Z J Psy- chiatry 2003;37:696-704.
  13. Proudfoot H, Baillie AJ, Teesson M. The structure of alcohol dependence in the Australian community. Drug Alcohol Depend 2006;81:21-6.
  14. Sunderland M, Mewton L, Slade T, Baillie AJ. Investigating differential symptom profiles in major depressive episode with and without generalized anxiety disorder: true co-morbidity or symptom similarity? Psychol Med 2009; Doi: http://dx.doi.org/10.1017/S0033291709991590. · DOI
  15. Kushner MG, Krueger RF, Frye B, Peterson J. Epidemio- logical perspectives on co-occuring anxiety disorder and substance use disorder. In: Stewart SH, Conrod PJ, eds. Anxiety and substance use disorders: the vicious cycle of comorbidity. New York: Springer, 2008:3-17.
  16. Buckner JD, Turner RJ. Social anxiety disorder as a risk factor for alcohol use disorders: a prospective examination of parental and peer influences. Drug Alcohol Depend 2009;100:128-37.
  17. McEvoy PM, Shand F. The effect of comorbid substance use disorders on treatment outcome for anxiety disorders. J Anxiety Disord 2008;22:1087-98.
  18. Schade A, Marquenie LA, van Balkom AJ, et al. Anxiety disorders: treatable regardless of the severity of comorbid alcohol dependence. Eur Addict Res 2007;13:109-15.
  19. Burns L, Teesson M, O'Neill K. The impact of comorbid anxiety and depression on alcohol treatment outcomes. Addiction 2005;100:787-96.
  20. Dingle GA, King P. Prevalence and impact of co-occurring psychiatric disorders on outcomes from a private hospital drug and alcohol treatment program. Ment Health Subst Use 2009;2:13-23.
  21. Marquenie LA, Schade A, Van Balkom A, et al. Comorbid phobic disorders do not influence outcome of alcohol dependence treatment. Results of a naturalistic follow-up study. Alcohol Alcohol 2006;41:168-73.
  22. Baillie A, Sannibale C. Anxiety and drug and alcohol prob- lems. In: Baker A, Velleman R, eds. Clinical handbook of co-existing mental health and drug and alcohol problems. London: Brunner-Routledge, 2007:195-214.
  23. Fals-Stewart W, Schafer J. The treatment of substance abusers diagnosed with obsessive-compulsive disorder: an outcome study. J Subst Abuse Treat 1992;9:365-70.
  24. Ormrod J, Budd R. A comparison of two treatment inter- ventions aimed at lowering anxiety levels and alcohol con- sumption amongst alcohol abusers. Drug Alcohol Depend 1991;27:233-43.
  25. Bowen RC, D'Arcy C, Keegan D, Senthilselvan A. A con- trolled trial of cognitive behavioral treatment of panic in alcoholic inpatients with comorbid panic disorder. Addict Behav 2000;25:593-7.
  26. Randall CL, Thomas S, Thevos AK. Concurrent alcohol- ism and social anxiety disorder: a first step toward develop- ing effective treatments. Alcohol Clin Exp Res 2001;25: 210-20.
  27. Toneatto T. Cognitive versus behavioral treatment of con- current alcohol dependence and agoraphobia: a pilot study. Addict Behav 2005;30:115-25.
  28. Montori VM, Wilczynski NL, Morgan D, Haynes RB, for the Hedges Team. Optimal search strategies for retrieving systematic reviews from Medline: analytical survey. BMJ 2005;330:68-76.
  29. Najavits LM, Harned MS, Gallop RJ, et al. Six-month treat- ment outcomes of cocaine-dependent patients with and without PTSD in a multisite national trial. J Stud Alcohol Drugs 2007;68:353-61.
  30. Najavits LM, Schmitz M, Gotthardt S, Weiss RD. Seeking safety plus exposure therapy: an outcome study on dual diagnosis men. J Psychoactive Drugs 2005;37:425- 35.
  31. Back SE, Brady KT, Sonne SC, Verduin ML. Symptom improvement in co-occurring PTSD and alcohol depen- dence. J Nerv Ment Dis 2006;194:690-6.
  32. Brady KT, Sonne S, Anton RF, Randall CL, Back SE, Simpson K. Sertraline in the treatment of co-occurring alcohol dependence and posttraumatic stress disorder. Alcohol Clin Exp Res 2005;29:395-401.
  33. Stewart SH, Kushner MG. Introduction to the special issues on 'Anxiety sensitivity and addictive behaviors'. Addict Behav 2001;26:775-85.
  34. Conrod PJ, Stewart SH, Comeau N, Maclean AM. Efficacy of cognitive-behavioral interventions targeting personality risk factors for youth alcohol misuse. J Clin Child Adolesc Psychol 2006;35:550-63.
  35. Kushner MG, Sletten S, Donahue C, et al. Cognitive- behavioral therapy for panic disorder in patients being treated for alcohol dependence: moderating effects of alcohol outcome expectancies. Addict Behav 2009;34:554- 60.
  36. Kushner MG, Donahue C, Sletten S, et al. Cognitive behavioral treatment of comorbid anxiety disorder in alco- holism treatment patients: presentation of a prototype program and future directions. J Ment Health 2006;15:697-707.
  37. Goldman MS, Brown SA, Christiansen BA. Expectancy theory: thinking about drinking. In: Blane HT, Leonard KE, eds. Psychological theories of drinking and alcoholism. New York: Guilford Press, 1987:181-226.
  38. Thomas SE, Randall PK, Book SW, Randall CL. A complex relationship between co-occurring social anxiety and alcohol use disorders: what effect does treating social anxiety have on drinking? Alcohol Clin Exp Res 2008;32:77-84.
  39. Book SW, Thomas SE, Randall PK, Randall CL. Paroxet- ine reduces social anxiety in individuals with a co-occurring alcohol use disorder. J Anxiety Disord 2008;22:310-18.
  40. Malat J, Leszcz M, Negrete JC, et al. Interpersonal group psychotherapy for comorbid alcohol dependence and non- psychotic psychiatric disorders. Am J Addict 2008;17: 402-7.
  41. First MB, Spitzer RL, Gibbon M, Williams JBW. Struc- tured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. (SCID-I/P). New York: Biometrics Research, New York State Psychiatric Institute, 2002.
  42. Brown TA, DiNardo P, Barlow DH. Anxiety disorder inter- view schedule. New York: Oxford, 2004.
  43. Spitzer RL. Psychiatric diagnosis: are clinicians still neces- sary? Compr Psychiatry 1983;24:399-411.
  44. Kranzler HR, Kadden RM, Burleson JA, Babor TF, Apter A, Rounsaville BJ. Validity of psychiatric diagnoses in patients with substance use disorders: is the interview more important than the interviewer? Compr Psychiatry 1995;36:278-88.
  45. Kushner MG, Kenneth JS, Erickson DJ. Prospective analysis of the relation betwen DSM III anxiety disorders and alcohol use disorder. Am J Psychiatry 1999;156:723- 32.

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Authors
BAILLIE, A. J., STAPINSKI, L., CROME, E., MORLEY, K., SANNIBALE, C., HABER, P., & TEESSON, M.
Affiliations
  • Macquarie University (AU)
  • The University of Sydney (AU)
  • Royal Prince Alfred Hospital (AU)
  • UNSW Sydney (AU)
Corresponding author
BAILLIE, ANDREW J.
Venue
Drug and Alcohol Review
Publisher
Wiley
Published
2010-09
Volume
29
Issue
5
Pages
518-524
ISSN
  • 0959-5236 (ISSN-L)
  • 1465-3362
OpenAlex
W2097945280
Cited by
33
References
12
Citations by year
2024: 2 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 6 · 2019: 1 · 2017: 2 · 2016: 3 · 2014: 5 · 2013: 1 · 2012: 6
FWCI
0.33
Type
journal article
Language
en
Open access
Locations
  • Drug and Alcohol Review (publishedVersion)
  • PubMed (publishedVersion)
  • Explore Bristol Research (submittedVersion)
Funders
  • Macquarie University
  • Medical Research Council
  • National Health and Medical Research Council
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords
anxiety disorders, substance use disorders, comorbidities, psychological intervention, anxiety sensitivity, tension reduction, alcohol expectancies
MeSH terms
Anxiety Disorders, Clinical Trials as Topic, Humans, Psychotherapy, Research Design, Treatment Outcome, Diagnosis, Dual (Psychiatry), Substance-Related Disorders

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