Primary anxiety disorders and the development of subsequent alcohol use disorders: a 4-year community study of adolescents and young adults
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Background. Cross-sectional findings in community surveys of adults suggest that adolescent anxiety disorders are strong predictors of the subsequent onset of alcohol use, abuse and dependence. However, prospective data that follow a sample of adolescents into adulthood are needed to confirm these associations. Method. Baseline and 4-year follow-up data from the EDSP-Study, a prospective community survey of 3021 (2548 at follow-up) adolescents and young adults aged 14 to 24 years at baseline carried out in Munich, were used. DSM-IV anxiety disorders, alcohol use and alcohol use disorders were assessed with the Munich-Composite-International-Diagnostic-Interview (M-CIDI). Multiple logistic regression analysis, controlling for age, gender, other mental disorders, substance use disorders and antisocial behaviour was used to study the associations of baseline anxiety disorders with the subsequent onset and course of alcohol use and alcohol disorders. Results. Baseline social phobia significantly predicts the onsets of regular use and hazardous use and the persistence of dependence. Panic attacks significantly predict the onsets of hazardous use and abuse as well as the persistence of combined abuse/dependence. Panic disorder significantly predicts the persistence of combined abuse/dependence. Other anxiety disorders do not significantly predict any of the outcomes. Conclusions. Panic and social phobia are predictors of subsequent alcohol problems among adolescents and young adults. Further studies are needed to investigate the underlying mechanisms and the potential value of targeted early treatment of primary panic and social phobia to prevent secondary alcohol use disorders.
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There is a relationship between anxiety disorders such as PD and strikingly high rates of comorbidity and prospective onset of alcohol and tobacco use disorders among these individuals.
“This seems notable, given the relationship between anxiety disorders, such as PD, and the strikingly high rates of comorbidity and prospective onset of alcohol and tobacco use disorders among these individuals (Zimmermann et al., 2003; Zvolensky, Bernstein, Marshall, & Feldner, 2006).”
From Cued for Risk: Evidence for an Incentive Sensitization Framework to Explain the Interplay between Stress and Anxiety, Substance Abuse, and Reward Uncertainty in Disordered Gambling Behavior (2019) · cites this paper as Zimmermann et al., 2003
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- Authors
- ZIMMERMANN, P., WITTCHEN, H.-U., HÖFLER, M., PFISTER, H., KESSLER, R. C., & LIEB, R.
- Affiliations
- Harvard University (US)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2003-09-25
- Volume
- 33
- Issue
- 7
- Pages
- 1211-1222
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2142342583
- Cited by
- 366
- References
- 61
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 3 · 2023: 11 · 2022: 10 · 2021: 5 · 2020: 36 · 2019: 7 · 2018: 15 · 2017: 21 · 2016: 22 · 2015: 21 · 2014: 20 · 2013: 28 · 2012: 17
- FWCI
- 7.43
- Type
- journal article
- Language
- en
- Open access
- green
- tud.qucosa.de
- Licence
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Qucosa (Saxon State and University Library Dresden) (submittedVersion, other-oa)
- Funders
- National Institute on Drug Abuse (R01DA011121)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- alcoholism, social anxiety disorder, panic disorder, panic attacks, adolescents, young adults, hazardous drinking, alcohol abuse
- MeSH terms
- Adolescent, Adult, Alcoholism, Anxiety Disorders, Cross-Sectional Studies, Female, Germany, Humans, Longitudinal Studies, Male, Phobic Disorders, Prospective Studies, Risk Factors, Comorbidity, Causality, Panic Disorder
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