The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment
Abstract
Summary: Recent research suggests that increased adiposity is associated with poor cognitive performance, independently of associated medical conditions. The evidence regarding this relationship is examined in this review article. A relatively consistent finding across the lifespan is that obesity is associated with cognitive deficits, especially in executive function, in children, adolescents and adults. However, as illustrated by contradictory studies, the relationship between obesity and cognition is uncertain in the elderly, partly because of inaccuracy of body mass index as a measure of adiposity as body composition changes with aging. This review further discusses whether obesity is a cause or a consequence of these cognitive deficits, acknowledging the possible bidirectional relationship. The possible effects of increased adiposity on the brain are summarized. Our investigations suggest that weight gain results, at least in part, from a neurological predisposition characterized by reduced executive function, and in turn obesity itself has a compounding negative impact on the brain via mechanisms currently attributed to low‐grade systemic inflammation, elevated lipids and/or insulin resistance. The possible role of cognitive remediation treatment strategies to prevent and/or treat obesity is discussed.
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Cited by
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Intelligence and school grades: A meta-analysis
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Executive Function Performance in Obesity and Overweight Individuals: A Meta-Analysis and Review
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Impact of Metabolic Syndrome on Cognition and Brain: A Selected Review of the Literature
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Recommendations for the Presurgical Psychosocial Evaluation of Bariatric Surgery Patients
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Metadata
- Authors
- Smith, E., Hay, P., Campbell, L., & Trollor, J. N.
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2011-08-22
- Volume
- 12
- Issue
- 9
- Pages
- 740-755
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W1561112770
- Cited by
- 707
- References
- 115
- FWCI
- 29.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- Smith, E., Hay, P., Campbell, L., & Trollor, J. N. (2011). A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment. Obesity Reviews. https://doi.org/10.1111/j.1467-789x.2011.00920.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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