CoChat
Sign Up
Cited by 318Diet and metabolism studiesDietary Effects on HealthNutritional Studies and Diet

The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.

Systematic review and meta‐analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors

Santos, F. L., Esteves, S. S., da Costa Pereira, A., Yancy Jr, W. S., Nunes, J. P. L.·2012·Obesity Reviews
DOI 10.1111/j.1467-789x.2012.01021.x
Open this paper in CoChat — free account

Abstract

Summary: A systematic review and meta‐analysis were carried out to study the effects of low‐carbohydrate diet (LCD) on weight loss and cardiovascular risk factors (search performed on PubMed, Cochrane Central Register of Controlled Trials and Scopus databases). A total of 23 reports, corresponding to 17 clinical investigations, were identified as meeting the pre‐specified criteria. Meta‐analysis carried out on data obtained in 1,141 obese patients, showed the LCD to be associated with significant decreases in body weight (−7.04 kg [95% CI −7.20/−6.88]), body mass index (−2.09 kg m−2[95% CI −2.15/−2.04]), abdominal circumference (−5.74 cm [95% CI −6.07/−5.41]), systolic blood pressure (−4.81 mm Hg [95% CI −5.33/−4.29]), diastolic blood pressure (−3.10 mm Hg [95% CI −3.45/−2.74]), plasma triglycerides (−29.71 mg dL−1[95% CI −31.99/−27.44]), fasting plasma glucose (−1.05 mg dL−1[95% CI −1.67/−0.44]), glycated haemoglobin (−0.21% [95% CI −0.24/−0.18]), plasma insulin (−2.24 micro IU mL−1[95% CI −2.65/−1.82]) and plasma C‐reactive protein, as well as an increase in high‐density lipoprotein cholesterol (1.73 mg dL−1[95%CI 1.44/2.01]). Low‐density lipoprotein cholesterol and creatinine did not change significantly, whereas limited data exist concerning plasma uric acid. LCD was shown to have favourable effects on body weight and major cardiovascular risk factors; however the effects on long‐term health are unknown.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/j.1467-789x.2012.01021.x

Cites

75 of 75 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 75 references

Research works printed but not linked: 2

  1. Atkins RC, 2002, Dr. Atkins New Diet Revolution (Revised Edition)
  2. Confucius, 1979, Analects

Cited by

Sorted by citations

Items 201–300 of 317

Related

See all

Metadata

Authors
Santos, F. L., Esteves, S. S., da Costa Pereira, A., Yancy Jr, W. S., & Nunes, J. P. L.
Affiliations
  • Centro Hospitalar de Vila Nova de Gaia (PT)
  • Centro Hospitalar do Porto (PT)
  • Universidade do Porto (PT)
Corresponding author
Nunes, J. P. L.
ORCID
Venue
Obesity Reviews
Publisher
Wiley
Published
2012-08-21
Volume
13
Issue
11
Pages
1048-1066
ISSN
  • 1467-7881 (ISSN-L)
  • 1467-789X
DOI
10.1111/j.1467-789x.2012.01021.x
OpenAlex
W2110483590
Cited by
318
References
75
Citations by year
2026: 10 · 2025: 20 · 2024: 24 · 2023: 25 · 2022: 16 · 2021: 29 · 2020: 34 · 2019: 16 · 2018: 28 · 2017: 19 · 2016: 25 · 2015: 26 · 2014: 21 · 2013: 23 · 2012: 1
FWCI
2.48
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Obesity Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
  • Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords
low-carbohydrate diet, cardiovascular risk factors, weight loss, obesity, blood pressure, triglycerides, fasting blood glucose, HbA1c, insulin, C-reactive protein, HDL cholesterol, LDL cholesterol, uric acid, abdominal circumference
MeSH terms
Blood Glucose, Blood Pressure, Cardiovascular Diseases, Cholesterol, Dietary Carbohydrates, Humans, Insulin, Risk Factors, Triglycerides, Weight Loss, Randomized Controlled Trials as Topic, Treatment Outcome, Diet, Carbohydrate-Restricted

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review