The DOI matches its Crossref record; 22 of the 23 references it cites were found in a registry or an index.
Prevalence of risk factors for cardiovascular disease in HIV-infected patients over time: the Swiss HIV Cohort Study
Open accessAbstract
Objective: Metabolic changes caused by antiretroviral therapy (ART) may increase the risk of coronary heart disease (CHD). We evaluated changes in the prevalence of cardiovascular risk factors (CVRFs) and 10‐year risk of CHD in a large cohort of HIV‐infected individuals. Methods: All individuals from the Swiss HIV Cohort Study (SHCS) who completed at least one CVRF questionnaire and for whom laboratory data were available for the period February 2000 to February 2006 were included in the analysis. The presence of a risk factor was determined using cut‐offs based on the guidelines of the National Cholesterol Education Program (NCEP ATP III), the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7), the American Diabetes Association, and the Swiss Society for Cardiology. Results: Overall, 8033 individuals completed at least one CVRF questionnaire. The most common CVRFs in the first completed questionnaire were smoking (57.0%), low high‐density lipoprotein (HDL) cholesterol (37.2%), high triglycerides (35.7%), and high blood pressure (26.1%). In total, 2.7 and 13.8% of patients were categorized as being at high (>20%) and moderate (10–20%) 10‐year risk for CHD, respectively. Over 6 years the percentage of smokers decreased from 61.4 to 47.6% and the percentage of individuals with total cholesterol >6.2 mmol/L decreased from 21.1 to 12.3%. The prevalence of CVRFs and CHD risk was higher in patients currently on ART than in either pretreated or ART‐naive patients. Conclusion: During the 6‐year observation period, the prevalence of CVRFs remains high in the SHCS. Time trends indicate a decrease in the percentage of smokers and individuals with high cholesterol.
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“Highly active antiretroviral treatment (HAART) causes an increase of LDL-C and TG, and predominance of small, dense LDL particles, thus doubling their CAD risk when compared with HIV-negative subjects.212”
From ESC/EAS Guidelines for the management of dyslipidaemias (2011) · cites this paper as [212]
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Standards of Medical Care in Diabetes
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Combination Antiretroviral Therapy and the Risk of Myocardial Infarction
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Self-citationStandards of Medical Care in Diabetes
(2004) · Diabetes Care · doi:10.2337/diacare.27.2007.s15 · Cited by 688
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Research works printed but not linked: 3
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- El SadrW NeatonJ NeuhausJ GordinF.Comparison of risk factors for coronary heart disease among men and women enrolled in the SMART Study (CPCRA 065).10th Conference on Retrovirus and Opportunistic Infections. Boston MA February 2003 [Abstract 745].
- GlassT VernazzaP WeberRet al. Predictors of successful cardiovascular risk factor management in HIV‐infected patients at moderate to high 10 years risk of coronary heart disease: The Swiss HIV Cohort Study.10th European AIDS Conference/EACS. Dublin Ireland November 2005 [Abstract PE9.5/8].
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ESC/EAS Guidelines for the management of dyslipidaemias
Reiner, Ž., Catapano, A. L., De Backer, G., Graham, I., Taskinen, M.-R., Wiklund, O., Agewall, S., Alegria, E., Chapman, M. J., Durrington, P., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr158 · Cited by 3,549
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162
ESC/EAS Guidelines for the management of dyslipidaemias
Catapano, A. L., Reiner, Ž., De Backer, G., Graham, I., Taskinen, M.-R., Wiklund, O., Agewall, S., Alegria, E., Chapman, M. J., Durrington, P., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.06.028 · Cited by 706
Worm, S. W., Sabin, C. A., Weber, R. K., Reiss, P., El-Sadr, W. M., Dabis, F., Wit, S. D., Law, M. G., Monforte, A. D., Friis‐Møller, N., et al. (2009) · The Journal of Infectious Diseases · doi:10.1086/649897 · Cited by 644
“MI Risk and Antiretroviral Therapy • JID 2010:201 (1 February) • 319 general population [1], although the situation has improved somewhat over the past few years [2, 3].”
BackgroundSelf-citationHIV infection and cardiovascular disease
Hemkens, L. G., & Bucher, H. C. (2014) · European Heart Journal · doi:10.1093/eurheartj/eht528 · Cited by 251
“In D:A:D, a substantial discrepancy between ART-treated and treatment-naı̈ve patients with regard to raised triglyceride and total cholesterol levels was found, which was also observed in more recent analyses.(10) Although more HIV-infected patients are treated with lipid and blood pressure-lowering drugs, data from a…”
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Metadata
- Authors
- Glass, T., Ungsedhapand, C., Wolbers, M., Weber, R., Vernazza, P., Rickenbach, M., Furrer, H., Bernasconi, E., Cavassini, M., Hirschel, B., Battegay, M., Bucher, H., & Study, T. S. H. C.
- Affiliations
- University Hospital of Basel (CH)
- University Hospital Zurich (CH)
- Kantonsspital St. Gallen (CH)
- Centre Hospitalier Universitaire Vaudois (CH)
- University Hospital of Bern (CH)
- Ospedale regionale di Lugano (CH)
- University Hospital of Geneva (CH)
- Venue
- HIV Medicine
- Publisher
- Wiley
- Published
- 2006-07-24
- Volume
- 7
- Issue
- 6
- Pages
- 404-410
- ISSN
- 1464-2662 (ISSN-L)
- 1468-1293
- OpenAlex
- W2068156414
- Cited by
- 156
- References
- 23
- Citations by year
- 2025: 2 · 2024: 1 · 2022: 3 · 2021: 6 · 2020: 3 · 2019: 9 · 2018: 3 · 2017: 11 · 2016: 13 · 2015: 17 · 2014: 13 · 2013: 11 · 2012: 12
- FWCI
- 11.13
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- HIV Medicine (publishedVersion)
- PubMed (publishedVersion)
- BORIS (University Library Bern) (submittedVersion)
- IRIS (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Funders
- American Diabetes Association
- Cardiovascular Research Foundation
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- cardiovascular risk factors, HIV infection, coronary artery disease, antiretroviral therapy, metabolic changes, smoking, hypercholesterolemia, HDL cholesterol, triglycerides, hypertension, 10-year cardiovascular risk, temporal trends, Swiss HIV Cohort Study
- MeSH terms
- Adult, Cardiovascular Diseases, Diabetes Mellitus, Humans, Hypertension, Middle Aged, Surveys and Questionnaires, Risk Factors, Switzerland, Time Factors, Cohort Studies, HIV Infections, Prevalence, Practice Guidelines as Topic, Risk Assessment, Antiretroviral Therapy, Highly Active, Dyslipidemias
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