Cited by 500Biosensors and Analytical DetectionClinical Laboratory Practices and Quality ControlBacterial Identification and Susceptibility Testing

The DOI matches its Crossref record; 53 of the 56 references it cites were found in a registry or an index.

Point-of-care tests for diagnosing infections in the developing world

Open access

Peeling, R.W., Mabey, D.·2010·Clinical Microbiology and Infection

DOI 10.1111/j.1469-0691.2010.03279.x

Open this paper in CoChat — free account

Abstract

Infectious diseases continue to cause an enormous burden of death and disability in developing countries. Increasing access to appropriate treatment for infectious diseases could have a major impact on disease burden. Some common infections can be managed syndromically without the need for diagnostic tests, but this is not appropriate for many infectious diseases, in which a positive diagnostic test is needed before treatment can be given. Since many people in developing countries do not have access to laboratory services, diagnosis depends on the availability of point of care (POC) tests. Historically there has been little investment in POC tests for diseases that are common in developing countries, but that is now changing. Lack of regulation of diagnostic tests in many countries has resulted in the widespread use of sub-standard POC tests, especially for malaria, making it difficult for manufacturers of reliable POC tests to compete. In recent years increased investment, technological advances, and greater awareness about the importance of reliable diagnostic tests has resulted in rapid progress. Rapid, reliable and affordable POC tests, requiring no equipment and minimal training, are now available for HIV infection, syphilis and malaria, but POC tests for other infections are urgently needed. Many countries do not have established criteria for licensing and introducing new diagnostic tests, and many clinicians in developing countries have become disillusioned with diagnostic tests and prefer to rely on clinical judgment. Continuing advocacy and training in the use of POC tests are needed, and systems for quality control of POC tests need to be developed if they are to achieve their maximum potential.

Integrity signals

Registry

Crossref · 10.1111/j.1469-0691.2010.03279.x

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

DNA Detection Using Recombination Proteins
Piepenburg, O., Williams, C. H., Stemple, D. L., & Armes, N. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040204 · Cited by 2,503
WHO estimates of the causes of death in children
Bryce, J., Boschi-Pinto, C., Shibuya, K., & Black, R. E. (2005) · The Lancet · doi:10.1016/s0140-6736(05)71877-8 · Cited by 2,108
World Development Report 2004 : making services work for poor people
Pritchett, L. H., Gauthier, B., Devarajan, S., Filmer, D. P., Commins, S. K., Hammer, J. S., Shah, S., Soucat, A. L. B., & Aḥmad, J. (2003) · Cited by 1,517
Point-of-Care Diagnostics for Global Health
Yager, P., Domingo, G. J., & Gerdes, J. (2008) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.10.061807.160524 · Cited by 1,076
Diagnostics for the developing world
Mabey, D., Peeling, R. W., Ustianowski, A., & Perkins, M. D. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro841 · Cited by 1,054
Self-citation
Bacteremia among Children Admitted to a Rural Hospital in Kenya
Berkley, J. A., Lowe, B. S., Mwangi, I., Williams, T., Bauni, E., Mwarumba, S., Ngetsa, C., Slack, M. P. E., Njenga, S., Hart, C. A., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa040275 · Cited by 851
Laboratory medicine in Africa: a barrier to effective health care
Petti, C. A., Polage, C. R., Quinn, T. C., Ronald, A. R., & Sande, M. A. (2006) · Clinical Infectious Diseases · doi:10.1086/499363 · Cited by 749
Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study
Reyburn, H., Mbatia, R., DRAKELEY, C. J., Carneiro, I. A., Mwakasungula, E., Mwerinde, O., Saganda, K., Shao, J. F., Kitua, A. Y., Olomi, R. M., et al. (2004) · BMJ · doi:10.1136/bmj.38251.658229.55 · Cited by 675
Rapid tests for sexually transmitted infections (STIs): the way forward
Peeling, R. W. W., Holmes, K. K., Mabey, D. C. W., & Ronald, A. (2006) · Sexually Transmitted Infections · doi:10.1136/sti.2006.024265 · Cited by 601
Self-citation
Requirements for high impact diagnostics in the developing world
Urdea, M. S., Penny, L., Olmsted, S. S., Giovanni, M. Y., Kaspar, P., Shepherd, A., Wilson, P. L., Dahl, C. A., Buchsbaum, S., Moeller, G., et al. (2006) · Nature · doi:10.1038/nature05448 · Cited by 589

Show all 56 references

Sorted by citations

Paper-based microfluidic point-of-care diagnostic devices
Yetisen, A. K., Akram, M. S., & Lowe, C. R. (2013) · Lab on a Chip · doi:10.1039/c3lc50169h · Cited by 2,017
Point of Care Diagnostics: Status and Future
Gubala, V., Harris, L. F., Ricco, A. J., Tan, M. X., & Williams, D. E. (2011) · Analytical Chemistry · doi:10.1021/ac2030199 · Cited by 1,228
Beyond too little, too late and too much, too soon: a pathway towards evidence-based, respectful maternity care worldwide
Miller, S., Abalos, E., Chamillard, M., Ciapponi, A., Colaci, D., Comandé, D., Diaz, V., Geller, S., Hanson, C., Langer, A., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31472-6 · Cited by 1,181
Point-of-care nucleic acid testing for infectious diseases
Niemz, A., Ferguson, T. M., & Boyle, D. S. (2011) · Trends in biotechnology · doi:10.1016/j.tibtech.2011.01.007 · Cited by 838
Diagnostic point-of-care tests in resource-limited settings
Drain, P. K., Hyle, E. P., Noubary, F., Freedberg, K. A., Wilson, D., Bishai, W. R., Rodriguez, W. R., & Bassett, I. V. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70250-0 · Cited by 755
Point-of-Care Testing for Infectious Diseases: Diversity, Complexity, and Barriers in Low- And Middle-Income Countries
Pai, N. P., Vadnais, C., Denkinger, C. M., Engel, N., & Pai, M. (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001306 · Cited by 597
Point-of-care testing (POCT) diagnostic systems using microfluidic lab-on-a-chip technologies
Jung, W., Han, J., Choi, J., & Ahn, C. H. (2014) · Microelectronic Engineering · doi:10.1016/j.mee.2014.09.024 · Cited by 523
Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies
Aman, R. A., Mahas, A., & Mahfouz, M. M. (2020) · ACS Synthetic Biology · doi:10.1021/acssynbio.9b00507 · Cited by 416
Global Burden of Skin Disease: Inequities and Innovations
Seth, D., Cheldize, K., Brown, D., & Freeman, E. E. (2017) · Current Dermatology Reports · doi:10.1007/s13671-017-0192-7 · Cited by 366
Point-of-Care Diagnostics in Low Resource Settings: Present Status and Future Role of Microfluidics
Sharma, S., Zapatero-Rodríguez, J., Estrela, P., & O’Kennedy, R. J. (2015) · Biosensors · doi:10.3390/bios5030577 · Cited by 356
Handheld high-throughput plasmonic biosensor using computational on-chip imaging
Çetin, A. E., Coskun, A. F., Galarreta, B. C., Huang, M., Herman, D. H., Özcan, A., & Altug, H. (2014) · Light Science & Applications · doi:10.1038/lsa.2014.3 · Cited by 358
Cellulose: from biocompatible to bioactive material
Credou, J., & Berthelot, T. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb00431k · Cited by 357
Beyond the lateral flow assay: A review of paper-based microfluidics
Carrell, C. S., Kava, A. A., Nguyen, M., Menger, R. F., Munshi, Z., Call, Z. D., Nussbaum, M. A., & Henry, C. S. (2019) · Microelectronic Engineering · doi:10.1016/j.mee.2018.12.002 · Cited by 334
Recent advances in signal amplification strategy based on oligonucleotide and nanomaterials for microRNA detection-a review
Chen, Y., Huang, K., & Niu, K.-X. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.08.036 · Cited by 263
A Comparison of Optical, Electrochemical, Magnetic, and Colorimetric Point-of-Care Biosensors for Infectious Disease Diagnosis
Pashchenko, O. I., Shelby, T., Banerjee, T., & Santra, S. (2018) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.8b00023 · Cited by 239
Ultrafast photonic PCR
Son, J. H., Cho, B., Hong, S., Lee, S. H., Hoxha, O., Haack, A. J., & Lee, L. P. (2015) · Light Science & Applications · doi:10.1038/lsa.2015.53 · Cited by 235
Evaluation of a Newly Developed Lateral Flow Immunoassay for the Diagnosis of Cryptococcosis
Lindsley, M. D., Mekha, N., Baggett, H. C., Surinthong, Y., Autthateinchai, R., Sawatwong, P., Harris, J. R., Park, B. J., Chiller, T. M., Balajee, S. A., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir379 · Cited by 217
Towards a point-of-care test for active tuberculosis: obstacles and opportunities
McNerney, R., & Daley, P. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2521 · Cited by 208
Aptamer-based point-of-care diagnostic platforms
Dhiman, A., Kalra, P., Bansal, V., Bruno, J. G., & Sharma, T. K. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.02.060 · Cited by 204
Point-of-Care Tests to Strengthen Health Systems and Save Newborn Lives: The Case of Syphilis
Mabey, D. C. W., Sollis, K. A., Kelly, H. A., Benzaken, A. S., Bitarakwate, E., Changalucha, J. M., Chen, X., Yin, Y.-P., Garcia, P. J., Strasser, S., et al. (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001233 · Cited by 194
Self-citation
Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum
Bosch, I., de Puig, H., Hiley, M., Carré-Camps, M., Perdomo-Celis, F., Narváez, C. F., Salgado, D. M., Senthoor, D., O’Grady, M., Phillips, E., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aan1589 · Cited by 193
Development of a Panel of Recombinase Polymerase Amplification Assays for Detection of Biothreat Agents
Euler, M., Wang, Y., Heidenreich, D., Patel, P., Strohmeier, O., Hakenberg, S., Niedrig, M., Hufert, F. T., & Weidmann, M. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.02704-12 · Cited by 189
Malaria rapid diagnostic tests in endemic settings
Maltha, J., Gillet, P., & Jacobs, J. A. (2013) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12151 · Cited by 184
The Value and Future Developments of Multidisciplinary Team Cancer Care
Selby, P. J., Popescu, R. A., Lawler, M., Butcher, H., & Costa, A. (2019) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_236857 · Cited by 176
Engineering a sustainable future for point-of-care diagnostics and single-use microfluidic devices
Ongaro, A. E., Ndlovu, Z., Sollier, E., Otieno, C., Ondoa, P., Street, A., & Kersaudy-Kerhoas, M. (2022) · Lab on a Chip · doi:10.1039/d2lc00380e · Cited by 173
Rapid diagnosis of parasitic diseases: current scenario and future needs
Momčilović, S., Cantacessi, C., Arsić-Arsenijević, V. S., Otranto, D., & Otašević, S. (2018) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2018.04.028 · Cited by 183
Commercial Dengue Rapid Diagnostic Tests for Point-of-Care Application: Recent Evaluations and Future Needs?
Blacksell, S. D. (2012) · BioMed Research International · doi:10.1155/2012/151967 · Cited by 169
From the Bench to the Field in Low‐Cost Diagnostics: Two Case Studies
Kumar, A. A., Hennek, J. W., Smith, B. S., Kumar, S., Beattie, P. D., Jain, S., Rolland, J. P., Stossel, T. P., Chunda-Liyoka, C. M., & Whitesides, G. M. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201411741 · Cited by 162
Detecting Biothreat Agents: From Current Diagnostics to Developing Sensor Technologies
Walper, S. A., Lasarte‐Aragonés, G., Sapsford, K. E., Brown, C. W., Rowland, C. E., Breger, J. C., & Medintz, I. L. (2018) · ACS Sensors · doi:10.1021/acssensors.8b00420 · Cited by 163
Target-Responsive DNA Hydrogel Mediated “Stop-Flow” Microfluidic Paper-Based Analytic Device for Rapid, Portable and Visual Detection of Multiple Targets
Wei, X., Tian, T., Jia, S., Zhu, Z., Ma, Y., Sun, J., Lin, Z., & Yang, C. J. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b00532 · Cited by 158
The Point-of-Care Laboratory in Clinical Microbiology
Drancourt, M., Michel-Lepage, A., Boyer, S., & Raoult, D. (2016) · Clinical Microbiology Reviews · doi:10.1128/cmr.00090-15 · Cited by 155
Signal amplification strategies for paper-based analytical devices
Liu, L., Yang, D., & Liu, G. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.04.043 · Cited by 151
Are Treponema pallidum Specific Rapid and Point-of-Care Tests for Syphilis Accurate Enough for Screening in Resource Limited Settings? Evidence from a Meta-Analysis
Jafari, Y., Peeling, R. W. W., Shivkumar, S., Claessens, C., Joseph, L., & Pai, N. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054695 · Cited by 146
Self-citation
Update on laboratory diagnosis of amoebiasis
Saidin, S., Othman, N., & Noordin, R. (2018) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-018-3379-3 · Cited by 130
Evaluation and improvement of isothermal amplification methods for point-of-need plant disease diagnostics
Zou, Y., Mason, M. G., & Botella, J. R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235216 · Cited by 128
Detection of Acute HIV Infection: A Field Evaluation of the Determine® HIV-1/2 Ag/Ab Combo Test
Rosenberg, N. E., Kamanga, G., Phiri, S., Nsona, D., Pettifor, A. E., Rutstein, S. E., Kamwendo, D., Hoffman, I., Keating, M., Brown, L. B., et al. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir789 · Cited by 125
Point-of-Care Detection Devices for Food Safety Monitoring: Proactive Disease Prevention
Wu, M. Y.-C., Hsu, M., Chen, S., Hwang, D., Yen, T., & Cheng, C. (2017) · Trends in biotechnology · doi:10.1016/j.tibtech.2016.12.005 · Cited by 123
Impact of point‐of‐care CD4 testing on linkage to HIV care: a systematic review
Wynberg, E., Cooke, G., Shroufi, A., Reid, S. D., & Ford, N. P. (2014) · Journal of the International AIDS Society · doi:10.7448/ias.17.1.18809 · Cited by 121
Diagnostics as essential tools for containing antibacterial resistance
Okeke, I. N., Peeling, R. W. W., Goossens, H., Auckenthaler, R., Olmsted, S. S., de Lavison, J.-F., Zimmer, B. A., Perkins, M. D., & Nordqvist, K. (2011) · Drug Resistance Updates · doi:10.1016/j.drup.2011.02.002 · Cited by 124
Self-citation
CD-Based Microfluidics for Primary Care in Extreme Point-of-Care Settings
Smith, S., Mager, D., Perebikovsky, A., Shamloo, E., Kinahan, D. J., Mishra, R., Delgado, S. T., Kido, H., Saha, S., Ducrée, J., et al. (2016) · Micromachines · doi:10.3390/mi7020022 · Cited by 117
Nanobiosensors in diagnostics
Chamorro-García, A., & Merkoçi, A. (2016) · Nanobiomedicine · doi:10.1177/1849543516663574 · Cited by 118
Opportunities and Challenges for Cost-Efficient Implementation of New Point-of-Care Diagnostics for HIV and Tuberculosis
Schito, M. L., Peter, T. F., Cavanaugh, S., Piatek, A. S., Young, G. J., Alexander, H. L., Coggin, W. L., Domingo, G. J., Ellenberger, D., Ermantraut, E., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis044 · Cited by 115
Quantum dots-labeled strip biosensor for rapid and sensitive detection of microRNA based on target-recycled nonenzymatic amplification strategy
Deng, H., Liu, Q., Wang, X., Huang, R. Q., Liu, H., Lin, Q., Zhou, X., & Xing, D. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.09.043 · Cited by 107
Development a stacking pad design for enhancing the sensitivity of lateral flow immunoassay
Tsai, T., Huang, T.-H., Chen, C., Chou, Y., Chou, Y., & Chen, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-35694-9 · Cited by 107
Low-Cost Optical Assays for Point-of-Care Diagnosis in Resource-Limited Settings
Jiang, N., Tansukawat, N. D., Gonzalez‐Macia, L., Ates, H. C., Dincer, C., Güder, F., Taşoğlu, S., & Yetisen, A. K. (2021) · ACS Sensors · doi:10.1021/acssensors.1c00669 · Cited by 106
Early diagnosis of sepsis using serum biomarkers
Chan, T., & Gu, F. (2011) · Expert Review of Molecular Diagnostics · doi:10.1586/erm.11.26 · Cited by 109
Malaria Rapid Diagnostic Tests: Literary Review and Recommendation for a Quality Assurance, Quality Control Algorithm
Kavanaugh, M. J., Azzam, S., & Rockabrand, D. (2021) · Diagnostics · doi:10.3390/diagnostics11050768 · Cited by 102
Rapid diagnostic tests for non-malarial febrile illness in the tropics
Chappuis, F., Alirol, E., D’Acremont, V., Bottieau, E., & Yansouni, C. P. (2013) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12154 · Cited by 97
A Dual Point-of-Care Test Shows Good Performance in Simultaneously Detecting Nontreponemal and Treponemal Antibodies in Patients With Syphilis: A Multisite Evaluation Study in China
Yin, Y.-P., Chen, X., Wei, W.-H., Gong, K.-L., Cao, W., Yong, G., Feng, L., Huang, S., Wang, D.-M., Han, Y., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis928 · Cited by 95
Self-citation
Nanomaterials for molecular signal amplification in electrochemical nucleic acid biosensing: recent advances and future prospects for point-of-care diagnostics
Bezinge, L., Suea‐Ngam, A., deMello, A. J., & Shih, C. (2019) · Molecular Systems Design & Engineering · doi:10.1039/c9me00135b · Cited by 96
How Hidden Can Malaria Be in Pregnant Women? Diagnosis by Microscopy, Placental Histology, Polymerase Chain Reaction and Detection of Histidine-Rich Protein 2 in Plasma
Mayor, A., Moro, L., Aguilar, R., Bardají, A., Cisteró, P., Serra-Casas, E., Sigaúque, B., Alonso, P. L., Ordi, J., & Menéndez, C. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis236 · Cited by 92
Improving the Accessibility and Efficiency of Point-of-Care Diagnostics Services in Low- and Middle-Income Countries: Lean and Agile Supply Chain Management
Kuupiel, D., Bawontuo, V., & Mashamba-Thompson, T. P. (2017) · Diagnostics · doi:10.3390/diagnostics7040058 · Cited by 91
Clinically relevant analytical techniques, organizational concepts for application and future perspectives of point-of-care testing
Luppa, P. B., Bietenbeck, A., Beaudoin, C. A., & Giannetti, A. E. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.01.003 · Cited by 90
Nanoplasmonic On-Chip PCR for Rapid Precision Molecular Diagnostics
Lee, Y., Kang, B., Kang, M., Chung, D. R., Yi, G., Lee, L. P., & Jeong, K. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b23591 · Cited by 90
Analytical sensitivity and clinical sensitivity of the three rapid antigen detection kits for detection of SARS-CoV-2 virus
Mak, G. C. K., Lau, S. S. Y., Wong, K. K. Y., Chow, N. L. S., Lau, C. S., Lam, E. T. K., Chan, R. C. W., & Tsang, D. N. C. (2020) · Journal of Clinical Virology · doi:10.1016/j.jcv.2020.104684 · Cited by 88
Point-of-care diagnostic tests for tuberculosis disease
Hóng, J., Lee, H., Menon, N. V., Lim, C. T., Lee, L. P., & Ong, C. W. M. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abj4124 · Cited by 88
Direct writing electrodes using a ball pen for paper-based point-of-care testing
Li, Z., Li, F., Hu, J., Wee, W. H., Han, Y., Pingguan‐Murphy, B., Lu, T. J., & Xu, F. (2015) · The Analyst · doi:10.1039/c5an00620a · Cited by 86
Development of an Electrochemical Paper-Based Analytical Device for Trace Detection of Virus Particles
Channon, R. B., Yang, Y., Feibelman, K. M., Geiss, B. J., Dandy, D. S., & Henry, C. S. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b02042 · Cited by 85
Molecular-based isothermal tests for field diagnosis of malaria and their potential contribution to malaria elimination
Oriero, E. C., Jacobs, J. A., Geertruyden, J. V., Nwakanma, D. C., & D’Alessandro, U. (2014) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dku343 · Cited by 84
Emerging Resistance to Empiric Antimicrobial Regimens for Pediatric Bloodstream Infections in Malawi (1998–2017)
Tam, P. I., Musicha, P., Kawaza, K., Cornick, J., Denis, B., Freyne, B., Everett, D., Dube, Q., French, N., Feasey, N., et al. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/ciy834 · Cited by 83
Intelligent nanophotonics: when machine learning sheds light
Wu, N., Sun, Y., Hu, J., Yang, C., Bai, Z., Wang, F. X., Cui, X., He, S., Li, Y., Zhang, C., et al. (2025) · eLight · doi:10.1186/s43593-025-00085-x · Cited by 91
Target Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment
Porrás, A., Yadón, Z. E., Altcheh, J., Britto, C., Chaves, G. C., Flévaud, L., Martins‐Filho, O. A., Ribeiro, I., Schijman, A. G., Shikanai‐Yasuda, M. A., et al. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003697 · Cited by 81
Paper-based multiplexed vertical flow assay for point-of-care testing
Joung, H., Ballard, Z. S., Ma, A., Tseng, D. K., Teshome, H., Burakowski, S., Garner, O. B., Carlo, D. D., & Özcan, A. (2019) · Lab on a Chip · doi:10.1039/c9lc00011a · Cited by 78
Emerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance
Rentschler, S., Kaiser, L., & Deigner, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22010456 · Cited by 77
Electrochemical magnetic microbeads-based biosensor for point-of-care serodiagnosis of infectious diseases
Cortina, M. E., Melli, L. J., Roberti, M., Mass, M., Longinotti, G., Tropea, S., Lloret, P., Serantes, D. R., Salomón, F., Lloret, M., et al. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.01.021 · Cited by 77
Nucleic acid testing for tuberculosis at the point-of-care in high-burden countries
Niemz, A., & Boyle, D. S. (2012) · Expert Review of Molecular Diagnostics · doi:10.1586/erm.12.71 · Cited by 74
Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals
Khan, A. H., & Noordin, R. (2019) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-019-03680-2 · Cited by 72
Human African Trypanosomiasis Diagnosis in First-Line Health Services of Endemic Countries, a Systematic Review
Mitashi, P., Hasker, E. C., Lejon, V., Kandé, V., Muyembe, J., Lutumba, P. T., & Boelaert, M. (2012) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0001919 · Cited by 72
Emerging technologies in point-of-care molecular diagnostics for resource-limited settings
Peeling, R. W. W., & McNerney, R. (2014) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.2014.915748 · Cited by 74
Self-citation
Glycosylated gold nanoparticles in point of care diagnostics: from aggregation to lateral flow
Baker, A. N., Hawker-Bond, G., Georgiou, P. G., Dedola, S., Field, R. A., & Gibson, M. I. (2022) · Chemical Society Reviews · doi:10.1039/d2cs00267a · Cited by 71
Challenges and prospects for biomarker research: A current perspective from the developing world
Gupta, S., Venkatesh, A., Ray, S., & Srivastava, S. (2014) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2013.12.020 · Cited by 71
Barriers to Point-of-Care Testing in India: Results from Qualitative Research across Different Settings, Users and Major Diseases
Engel, N., Ganesh, G., Patil, M. R., Yellappa, V., Pai, N. P., Vadnais, C., & Pai, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135112 · Cited by 70
Enabling the Development and Deployment of Next Generation Point-of-Care Diagnostics
Derda, R., Gitaka, J., Klapperich, C. M., Mace, C. R., Kumar, A. A., Lieberman, M., Linnes, J. C., Jores, J., Nasimolo, J., Ndung’u, J. M., et al. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003676 · Cited by 67
Development of Multiplexed Infectious Disease Lateral Flow Assays: Challenges and Opportunities
Hanafiah, K. M., Arifin, N., Bustami, Y., Noordin, R., Garcia, M. L., & Anderson, D. (2017) · Diagnostics · doi:10.3390/diagnostics7030051 · Cited by 67
Towards Point-of-Care Insulin Detection
Soffe, R., Nock, V., & Chase, J. G. (2018) · ACS Sensors · doi:10.1021/acssensors.8b01253 · Cited by 71
Perspective on Diagnostics for Global Health
Fu, E. S., Yager, P., Floriano, P. N., Christodoulides, N. J., & McDevitt, J. T. (2011) · IEEE Pulse · doi:10.1109/mpul.2011.942766 · Cited by 66
Biosensing on the Centrifugal Microfluidic Lab-on-a-Disc Platform
Miyazaki, C. M., Carthy, É., & Kinahan, D. J. (2020) · Processes · doi:10.3390/pr8111360 · Cited by 64
High-throughput sample-to-answer detection of DNA/RNA in crude samples within functionalized micro-pipette tips
Lu, W., Wang, J., Wu, Q. D., Sun, J., Chen, Y., Zhang, L., Zheng, C., Gao, W., Liu, Y., & Jiang, X. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.08.016 · Cited by 64
Laboratory Diagnosis of HIV in Adults: A Review of Current Methods
Cornett, J., & Kirn, T. J. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit281 · Cited by 71
Naked-eye based point-of-care detection of E.coli O157: H7 by a signal-amplified microfluidic aptasensor
Li, T., Ou, G., Chen, X., Li, Z., Hu, R., Li, Y., Yang, Y., & Liu, M. (2020) · Analytica Chimica Acta · doi:10.1016/j.aca.2020.07.031 · Cited by 64
The potential of diagnostic point‐of‐care tests (POCTs) for infectious and zoonotic animal diseases in developing countries: Technical, regulatory and sociocultural considerations
Hobbs, E. C., Colling, A., Gurung, R. B., & Allen, J. (2020) · Transboundary and Emerging Diseases · doi:10.1111/tbed.13880 · Cited by 65
Integrated point-of-care testing (POCT) for HIV, syphilis, malaria and anaemia at antenatal facilities in western Kenya: a qualitative study exploring end-users’ perspectives of appropriateness, acceptability and feasibility
Young, N., Achieng, F., Desai, M. R., Phillips‐Howard, P. A., Hill, J., Aol, G., Bigogo, G., Laserson, K., ter Kuile, F. O., & Taegtmeyer, M. (2019) · BMC Health Services Research · doi:10.1186/s12913-018-3844-9 · Cited by 62
Ultrasensitive immunoassay for detection of Citrus tristeza virus in citrus sample using disposable microfluidic electrochemical device
Freitas, T. A., Proença, C. D. A., Baldo, T. A., Materón, E. M., Wong, A., Magnani, R. F., & Faria, R. C. (2019) · Talanta · doi:10.1016/j.talanta.2019.07.005 · Cited by 60
Pesticide Aptasensors—State of the Art and Perspectives
Phopin, K., & Tantimongcolwat, T. (2020) · Sensors · doi:10.3390/s20236809 · Cited by 60
Multi-reagents dispensing centrifugal microfluidics for point-of-care testing
Xiao, Y., Li, S., Pang, Z., Wan, C., Li, L., Yuan, H., Hong, X., Du, W., Feng, X., Li, Y., et al. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114130 · Cited by 59
Current Perspectives on Prevention of Mother-to-Child Transmission of Syphilis
Lago, E. G. (2016) · Cureus · doi:10.7759/cureus.525 · Cited by 59
Development of Mobile Laboratory for Viral Hemorrhagic Fever Detection in Africa
Weidmann, M., Faye, O., Faye, O., Wahed, A. A. E., Patel, P., Batéjat, C., Manuguerra, J., Adjami, A., Niedrig, M., Hufert, F. T., et al. (2018) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiy362 · Cited by 58
Ambient light-based optical biosensing platform with smartphone-embedded illumination sensor
Park, Y. M., Han, Y. D., Chun, H. J., & Yoon, H. C. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.09.007 · Cited by 58
Inkjet-printed microtiter plates for portable electrochemical immunoassays
Jović, M., Zhu, Y., Lesch, A. S., Bondarenko, A., Cortés‐Salazar, F., Gumy, F., & Girault, H. H. (2017) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2016.12.051 · Cited by 56
Deep Learning‐Enabled Multiplexed Point‐of‐Care Sensor using a Paper‐Based Fluorescence Vertical Flow Assay
Goncharov, A., Joung, H., Ghosh, R., Han, G., Ballard, Z. S., Maloney, Q., Bell, A. G., Aung, C. T. Z., Garner, O. B., Carlo, D. D., et al. (2023) · Small · doi:10.1002/smll.202300617 · Cited by 55
Simultaneous Detection of Antibiotic Resistance Genes on Paper-Based Chip Using [Ru(phen)2dppz]2+ Turn-on Fluorescence Probe
Li, B., Zhou, X., Liu, H., Deng, H., Huang, R. Q., & Xing, D. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b17653 · Cited by 54
Direct Blood PCR in Combination with Nucleic Acid Lateral Flow Immunoassay for Detection of Plasmodium Species in Settings Where Malaria Is Endemic
Mens, P. F., de Bes, H. M., Sondo, P., Laochan, N., Keereecharoen, L., van Amerongen, A., Flint, J., Sak, J. R. S., Proux, S., Tinto, H., et al. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.01426-12 · Cited by 53
Padlock probe-based rolling circle amplification lateral flow assay for point-of-need nucleic acid detection
Jain, S., Dandy, D. S., Geiss, B. J., & Henry, C. S. (2021) · The Analyst · doi:10.1039/d1an00399b · Cited by 52
Trends and projections of the global burden of thyroid cancer from 1990 to 2030
Hu, S., Wu, X., & Jiang, H. (2024) · Journal of Global Health · doi:10.7189/jogh.14.04084 · Cited by 52
Uptake of and factors associated with testing for sexually transmitted infections in community-based settings among youth in Zimbabwe: a mixed-methods study
Martin, K., Olaru, I. D., Buwu, N., Bandason, T., Marks, M., Dauya, E., Muzangwa, J., Mabey, D. C. W., Chikwari, C. D., Francis, S. C., et al. (2021) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(20)30335-7 · Cited by 51
Self-citation
Loop-Mediated Isothermal Amplification-Integrated CRISPR Methods for Infectious Disease Diagnosis at Point of Care
Yigci, D., Atçeken, N., Yetisen, A. K., & Taşoğlu, S. (2023) · ACS Omega · doi:10.1021/acsomega.3c04422 · Cited by 51
Towards Improving Point-of-Care Diagnosis of Non-malaria Febrile Illness: A Metabolomics Approach
Decuypere, S., Maltha, J., Deborggraeve, S., Rattray, N. J. W., Guiraud, I., Kaboré, B., Lompo, P., Tahita, M. C., Ruspasinghe, T., McConville, M. J., et al. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004480 · Cited by 51
Evaluation of a Rapid Diagnostic Test for Detection of Burkholderia pseudomallei in the Lao People's Democratic Republic
Woods, K. L., Boutthasavong, L., NicFhogartaigh, C., Lee, S. J., Davong, V., AuCoin, D. P., & Dance, D. A. B. (2018) · Journal of Clinical Microbiology · doi:10.1128/jcm.02002-17 · Cited by 51
Frugal Innovation for Point-of-Care Diagnostics Controlling Outbreaks and Epidemics
Miesler, T., Wimschneider, C., Brem, A., & Meinel, L. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.9b01712 · Cited by 51
Point of care testing of sports biomarkers: Potential applications, recent advances and future outlook
Sharma, A., Tok, A. I. Y., Palaniappan, A., & Liedberg, B. (2021) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2021.116327 · Cited by 50

Authors: Peeling, R. W., & Mabey, D.
Affiliations: London School of Hygiene & Tropical Medicine (GB)
Corresponding author: Peeling, R.W.
ORCID: Peeling, R.W.
Mabey, D.
Venue: Clinical Microbiology and Infection
Publisher: Elsevier BV
Published: 2010-08
Volume: 16
Issue: 8
Pages: 1062-1069
ISSN: 1198-743X (ISSN-L)
DOI: 10.1111/j.1469-0691.2010.03279.x
OpenAlex: W1748737970
Cited by: 500
References: 56
Citations by year: 2026: 31 · 2025: 19 · 2024: 30 · 2023: 20 · 2022: 23 · 2021: 27 · 2020: 45 · 2019: 37 · 2018: 47 · 2017: 36 · 2016: 44 · 2015: 45 · 2014: 29 · 2013: 32 · 2012: 18
FWCI: 1.73
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1606 d)
Locations: Clinical Microbiology and Infection (publishedVersion)
PubMed (publishedVersion)
Funders: Wellcome Trust
Topics: Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
Health Sciences › Medicine › Microbiology (medical) › Bacterial Identification and Susceptibility Testing
Keywords: point-of-care testing, infectious disease diagnosis, developing countries, malaria diagnosis, HIV testing, syphilis testing, diagnostic test regulation, syndromic management
MeSH terms: Developing Countries, Education, Medical, Continuing, Humans, Malaria, Quality Control, Syphilis, HIV Infections, Point-of-Care Systems, Molecular Diagnostic Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Point-of-care tests for diagnosing infections in the developing world

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks