The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Pulse Transit Time as an Indicator of Arterial Blood Pressure
Abstract
The relationship between pulse‐arrival times and diastolic blood pressure was measured in 10 anesthetized dogs. The pulse‐arrival time was measured using the R‐wave of the electrocardiogram (ECG) as a time reference. Pulse‐transit time was also measured between the carotid and femoral pulses. Blood pressure was raised with epinephrine injected intravenously and lowered with vagal stimulation. In all cases, pulse arrival and transit times decreased with an increase in diastolic pressure for diastolic pressures ranging from 15 to 250 mmHg. The correlation between pulse‐arrival time and pressure was poorest when the ECG was used as a timing reference. The best correlation was found with true pulse‐transit time and diastolic pressure. When pulse‐transit time was used to compute pulse‐wave velocity, it was found to increase nearly linearly with blood pressure. From 90–100 mmHg, the pulse‐wave velocity increased typically by slightly less than six percent.
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“A key example is the measurement of pulse arrival time (PAT), defined by the time lapse between the maximum fiducial point in the ECG signal (R peak) and the corresponding minimal fiducial point in the PPG signal at valley as in Fig. 6H, as a direct correlate to systolic blood pressure (29 , 30).”
From Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care (2019) · cites this paper as [30]
Citations
Cites
Pulse Wave Velocity as a Measure of Blood Pressure Change
Gribbin, B., Steptoe, A., & Sleight, P. (1976) · Psychophysiology · doi:10.1111/j.1469-8986.1976.tb03344.x · Cited by 227
Pulse Wave Velocity and Blood Pressure Change: Calibration and Applications
Steptoe, A., Smulyan, H., & Gribbin, B. (1976) · Psychophysiology · doi:10.1111/j.1469-8986.1976.tb00866.x · Cited by 172
THE EFFECT OF BLOOD PRESSURE ALTERATION ON THE PULSE WAVE VELOCITY
Nye, E. R. (1964) · Heart · doi:10.1136/hrt.26.2.261 · Cited by 103
Steptoe, A. (1976) · Psychophysiology · doi:10.1111/j.1469-8986.1976.tb00875.x · Cited by 45
Bramwell, J. C. (1924) · QJM · doi:10.1093/qjmed/os-17.67.225 · Cited by 8
Research works printed but not linked: 4
- Bazett H. C, Measurement of pulse wave velocity, American Journal of Physiology, 63, 1922
- Bramwell J. G., 1923, The effect of blood pressure on the extensibility of the human artery, Heart, 10, 289
- Geddes L. A., 1969, Pulse wave velocity as a continuous indicator of indirect blood pressure, Proceedings of the 14th Annual AA Ml Meeting, 14, 89
- McSwiney B. A., 1924, The effect of variations of blood pressure on pulse wave‐velocity (in man), Journal of Physiology, 49, 217
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Toward ubiquitous blood pressure monitoring via pulse transit time: Theory and practice
Mukkamala, R., Hahn, J.-O., Inan, O. T., Mestha, L. K., Kim, C.-S., Toreyin, H., & Kyal, S. (2015) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2015.2441951 · Cited by 935
“Since the level of the waveform feet is diastolic BP, such PTT measurements may best correspond to diastolic BP [44], [45].”
BackgroundInfluentialBinodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care
Chung, H. U., Kim, B. H., Lee, J. Y., Lee, J., Xie, Z., Ibler, E. M., Lee, K., Banks, A., Jeong, J. Y., Kim, J., et al. (2019) · Science · doi:10.1126/science.aau0780 · Cited by 807
Chen, W., Kobayashi, T., Ichikawa, S., Takeuchi, Y., & Togawa, T. (2000) · Medical & Biological Engineering & Computing · doi:10.1007/bf02345755 · Cited by 425
Smart Vest: Wearable multi-parameter remote physiological monitoring system
Pandian, P. S., Mohanavelu, K., Safeer, K. P., Kotresh, T. M., Shakunthala, D. T., Gopal, P., & Padaki, V. C. (2007) · Medical Engineering & Physics · doi:10.1016/j.medengphy.2007.05.014 · Cited by 420
Pulse transit time measured from the ECG: an unreliable marker of beat-to-beat blood pressure
Payne, R. A., Symeonides, C. N., Webb, D. J., & Maxwell, S. R. J. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00657.2005 · Cited by 418
Metadata
- Authors
- Geddes, L. A., Voelz, M. H., Babbs, C. F., Bourland, J. D., & Tacker, W. A.
- Affiliations
- Purdue University West Lafayette (US)
- Corresponding author
- Geddes, L. A.
- Venue
- Psychophysiology
- Publisher
- Wiley
- Published
- 1981-01
- Volume
- 18
- Issue
- 1
- Pages
- 71-74
- ISSN
- 0048-5772 (ISSN-L)
- 1469-8986
- OpenAlex
- W2163704183
- Cited by
- 293
- References
- 5
- Citations by year
- 2026: 10 · 2025: 13 · 2024: 13 · 2023: 14 · 2022: 15 · 2021: 22 · 2020: 22 · 2019: 18 · 2018: 23 · 2017: 12 · 2016: 14 · 2015: 8 · 2014: 11 · 2013: 3 · 2012: 8
- FWCI
- 3.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- pulse transit time, arterial blood pressure, diastolic blood pressure, pulse arrival time, pulse wave velocity, epinephrine, vagus nerve stimulation, dogs
- MeSH terms
- Animals, Blood Pressure, Dogs, Electrocardiography, Pulse
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