Fetal growth retardation and the arteries of the placental bed
Abstract
The morphology of the placental bed spiral arteries was studied in 68 pregnancies complicated by fetal growth retardation and in 40 pregnancies with a normally grown fetus. When the birth weight was normal the extent and depth of physiological vascular changes were normal except in those pregnancies complicated by pre-eclampsia. When the birth weight was low and the mothers were normotensive the extent and depth of physiological vascular changes were either normal or restricted, and in all patients with hypertension and a baby with low birth weight the physiological changes were restricted to the decidual segments of the spiral (uteroplacental) arteries. Acute atherosis was only found in pregnancies complicated by hypertension, particularly if there was proteinuria. We do not believe that there exists an arteriopathy which is common to hypertensive and normotensive pregnancies complicated by fetal growth retardation.
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The standardised placental volume (sPlaV) produces dimensionless and normally distributed results, making it more mathematically sound than the placental quotient.
“This produces dimensionless and normally distributed results making it more mathematically sound than the placental quotient from which it was derived, the latter being calculated as crown rump length (mm) divided by PlaV (mL or mm3) and having a unit of mm−2 [43].”
From Volume and vascularity: Using ultrasound to unlock the secrets of the first trimester placenta (2019) · cites this paper as [43]
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Volume and vascularity: Using ultrasound to unlock the secrets of the first trimester placenta
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- Authors
- Brosens, I., Dixon, H. G., & Robertson, W. B.
- Affiliations
- KU Leuven (BE)
- University of Bristol (GB)
- St George's Hospital (GB)
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 1977-09
- Volume
- 84
- Issue
- 9
- Pages
- 656-663
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W2000520991
- Cited by
- 430
- References
- 25
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 6 · 2022: 9 · 2021: 8 · 2020: 6 · 2019: 6 · 2018: 7 · 2017: 7 · 2016: 5 · 2015: 11 · 2014: 15 · 2013: 13 · 2012: 10
- FWCI
- 5.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- fetal growth restriction, uteroplacental arteries, preeclampsia, hypertension in pregnancy, low birth weight, acute atherosis, proteinuria
- MeSH terms
- Arteries, Birth Weight, Female, Fetal Growth Retardation, Gestational Age, Humans, Hypertension, Placenta, Pre-Eclampsia, Pregnancy, Pregnancy Complications, Cardiovascular
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