Pathophysiology of placental-derived fetal growth restriction
Open accessAbstract
Placental-related fetal growth restriction arises primarily due to deficient remodeling of the uterine spiral arteries supplying the placenta during early pregnancy. The resultant malperfusion induces cell stress within the placental tissues, leading to selective suppression of protein synthesis and reduced cell proliferation. These effects are compounded in more severe cases by increased infarction and fibrin deposition. Consequently, there is a reduction in villous volume and surface area for maternal-fetal exchange. Extensive dysregulation of imprinted and nonimprinted gene expression occurs, affecting placental transport, endocrine, metabolic, and immune functions. Secondary changes involving dedifferentiation of smooth muscle cells surrounding the fetal arteries within placental stem villi correlate with absent or reversed end-diastolic umbilical artery blood flow, and with a reduction in birthweight. Many of the morphological changes, principally the intraplacental vascular lesions, can be imaged using ultrasound or magnetic resonance imaging scanning, enabling their development and progression to be followed in vivo. The changes are more severe in cases of growth restriction associated with preeclampsia compared to those with growth restriction alone, consistent with the greater degree of maternal vasculopathy reported in the former and more extensive macroscopic placental damage including infarcts, extensive fibrin deposition and microscopic villous developmental defects, atherosis of the spiral arteries, and noninfectious villitis. The higher level of stress may activate proinflammatory and apoptotic pathways within the syncytiotrophoblast, releasing factors that cause the maternal endothelial cell activation that distinguishes between the 2 conditions. Congenital anomalies of the umbilical cord and placental shape are the only placental-related conditions that are not associated with maldevelopment of the uteroplacental circulation, and their impact on fetal growth is limited.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In placental insufficiency and preeclampsia cases, placental tissue often shows histological and macroscopic changes.
“In placental insufficiency and preeclampsia cases, placental tissue often shows histological and macroscopic changes25.”
From Multi-centre deep learning for placenta segmentation in obstetric ultrasound with multi-observer and cross-country generalization (2023) · cites this paper as [25]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Part of this paper’s reference list could not be split into single entries.
Signal integration in the endoplasmic reticulum unfolded protein response
Ron, D., & Walter, P. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2199 · Cited by 6,308 · see citing works
Mitochondrial free radical generation, oxidative stress, and aging
Cadenas, E., & Davies, K. J. A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00317-8 · Cited by 3,010 · see citing works
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
Hotamisligil, G. S. (2010) · Cell · doi:10.1016/j.cell.2010.02.034 · Cited by 2,802 · see citing works
Endoplasmic reticulum stress: cell life and death decisions
Xu, C. (2005) · Journal of Clinical Investigation · doi:10.1172/jci26373 · Cited by 2,260 · see citing works
The Pathology of the Human Placenta
Benirschke, K., & Driscoll, S. G. (1967) · Springer eBooks · doi:10.1007/978-1-4612-9809-0 · Cited by 2,123 · see citing works
From endoplasmic-reticulum stress to the inflammatory response
Zhang, K., & Kaufman, R. J. (2008) · Nature · doi:10.1038/nature07203 · Cited by 2,010 · see citing works
KHONG, T. Y., DE WOLF, F., ROBERTSON, W. B., & BROSENS, I. (1986) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1986.tb07830.x · Cited by 1,591 · see citing works
The “Great Obstetrical Syndromes” are associated with disorders of deep placentation
Brosens, I., Pijnenborg, R., Vercruysse, L., & Romero, R. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.08.009 · Cited by 1,568 · see citing works
The Uterine Spiral Arteries In Human Pregnancy: Facts and Controversies
Pijnenborg, R., Vercruysse, L., & HANSSENS, M. C. A. J. A. (2006) · Placenta · doi:10.1016/j.placenta.2005.12.006 · Cited by 1,201 · see citing works
Burton, G. J., Woods, A., Jauniaux, E. R. M., & Kingdom, J. C. (2009) · Placenta · doi:10.1016/j.placenta.2009.02.009 · Cited by 1,190 · see citing works
Self-citationOnset of Maternal Arterial Blood Flow and Placental Oxidative Stress
Jauniaux, E., Watson, A. L., Hempstock, J., Bao, Y.-P., Skepper, J. N., & Burton, G. J. (2000) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64849-3 · Cited by 1,057 · see citing works
Self-citationBurton, G. J., & Jauniaux, E. R. M. (2010) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2010.10.016 · Cited by 1,028 · see citing works
Self-citationIntrauterine growth restriction
Resnik, R. (2002) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(01)01780-x · Cited by 1,022 · see citing works
Hypoxia signalling through mTOR and the unfolded protein response in cancer
Wouters, B. G., & Koritzinsky, M. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2501 · Cited by 894 · see citing works
Guzy, R. D., & Schumacker, P. T. (2006) · Experimental Physiology · doi:10.1113/expphysiol.2006.033506 · Cited by 881 · see citing works
Poston, L., Briley, A. L., Seed, P. T., Kelly, F., & Shennan, A. H. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68433-x · Cited by 758 · see citing works
Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy.
Rodesch, F., Simon, P., Donner, C., & Jauniaux, E. R. M. (1992) · PubMed · Cited by 753 · see citing works
Self-citationFetal umbilical artery flow velocity waveforms and placental resistance: pathological correlation
Giles, W. B., Trudinger, B., & Baird, P. J. (1985) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1985.tb01045.x · Cited by 730 · see citing works
Placental Origins of Chronic Disease
Burton, G. J., Fowden, A. L., & Thornburg, K. L. (2016) · Physiological Reviews · doi:10.1152/physrev.00029.2015 · Cited by 717 · see citing works
Self-citationPlacental oxidative stress: from miscarriage to preeclampsia
Burton, G. J., & Jauniaux, E. (2004) · Journal of the Society for Gynecologic Investigation · doi:10.1016/j.jsgi.2004.03.003 · Cited by 673 · see citing works
Self-citationOxidative Stress in the Pathogenesis of Preeclampsia
Hubel, C. A. (1999) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.1999.d01-139.x · Cited by 673 · see citing works
Deng, J., Lu, P. D., Zhang, Y., Scheuner, D. L., Kaufman, R. J., Sonenberg, N., Harding, H. P., & Ron, D. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.23.10161-10168.2004 · Cited by 645 · see citing works
The Obstetric Origins of Health for a Lifetime
BARKER, D. J. P., & THORNBURG, K. L. (2013) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e31829cb9ca · Cited by 634 · see citing works
Jauniaux, E. R. M., Poston, L., & Burton, G. J. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml016 · Cited by 608 · see citing works
Self-citationBurton, G. J., Watson, A. L., Hempstock, J., Skepper, J. N., & Jauniaux, E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.6.8563 · Cited by 567 · see citing works
Self-citationJauniaux, E., Hempstock, J., Greenwold, N., & Burton, G. J. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63803-5 · Cited by 511 · see citing works
Self-citationSpiral Artery Remodeling and Trophoblast Invasion in Preeclampsia and Fetal Growth Restriction
Lyall, F., Robson, S. C., & Bulmer, J. N. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.01892 · Cited by 509 · see citing works
Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2
Hiby, S. E., Apps, R., Sharkey, A., Farrell, L. E., Gardner, L., Mulder, A., Claas, F. H. J., Walker, J. J., Redman, C. C., Morgan, L., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci43998 · Cited by 506 · see citing works
Pathology of the Human Placenta
Benirschke, K., Burton, G. J., & Baergen, R. N. (2012) · doi:10.1007/978-3-642-23941-0 · Cited by 502 · see citing works
Self-citationBurton, G. J., Jauniaux, E. R. M., & Watson, A. L. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70518-1 · Cited by 453 · see citing works
Self-citationJaddoe, V. W. V., de Jonge, L. L., Hofman, A., Franco, O. H., Steegers, E. A. P., & Gaillard, R. (2014) · BMJ · doi:10.1136/bmj.g14 · Cited by 443 · see citing works
Fetal and umbilical Doppler ultrasound in high-risk pregnancies
Alfirević, Ž., Stampalija, T., & Gyte, G. M. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007529.pub3 · Cited by 440 · see citing works
Classification of placental lesions
Redline, R. W. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.05.056 · Cited by 439 · see citing works
Fetal growth retardation and the arteries of the placental bed
Brosens, I., Dixon, H. G., & Robertson, W. B. (1977) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1977.tb12676.x · Cited by 430 · see citing works
Goswami, D., Tannetta, D., Magee, L. A., Fuchisawa, A., Redman, C. W. G., Sargent, I. L., & von Dadelszen, P. (2005) · Placenta · doi:10.1016/j.placenta.2004.11.007 · Cited by 402 · see citing works
Hung, T., Skepper, J. N., Jones, D. S., & Burton, G. J. (2002) · Circulation Research · doi:10.1161/01.res.0000024411.22110.aa · Cited by 397 · see citing works
Self-citationYung, H.-W., Calabrese, S., Hynx, D., Hemmings, B. A., Cetin, I., Charnock-Jones, D. S., & Burton, G. J. (2008) · The American Journal of Pathology · doi:10.2353/ajpath.2008.071193 · Cited by 388 · see citing works
Self-citationGerretsen, G., Huisjes, H. J., & Elema, J. D. (1981) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1981.tb02222.x · Cited by 370 · see citing works
Regulation of basal cellular physiology by the homeostatic unfolded protein response
Rutkowski, D. T., & Hegde, R. S. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201003138 · Cited by 370 · see citing works
Villitis of unknown etiology: noninfectious chronic villitis in the placenta
Redline, R. W. (2007) · Human Pathology · doi:10.1016/j.humpath.2007.05.025 · Cited by 360 · see citing works
The pattern of interstitial trophoblasticinvasion of the myometrium in early human pregnancy
Pijnenborg, R., Bland, J. M., Robertson, W. B., Dixon, G., & Brosens, I. A. (1981) · Placenta · doi:10.1016/s0143-4004(81)80027-6 · Cited by 354 · see citing works
Hustin, J., & Schaaps, J. (1987) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(87)80371-x · Cited by 343 · see citing works
Review: reactive oxygen and nitrogen species and functional adaptation of the placenta
Myatt, L. (2010) · Placenta · doi:10.1016/j.placenta.2009.12.021 · Cited by 330 · see citing works
Placental Pathology in Early-Onset and Late-Onset Fetal Growth Restriction
Mifsud, W., & Sebire, N. J. (2014) · Fetal Diagnosis and Therapy · doi:10.1159/000359969 · Cited by 328 · see citing works
Salafia, C. M., MINIOR, V. K., Pezzullo, J. C., Popek, E. J., Rosenkrantz, T. S., & Vintzileos, A. M. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)91325-4 · Cited by 308 · see citing works
The influence of the intrauterine environment on human placental development
Burton, G. J., Jauniaux, E., & Charnock-Jones, D. S. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.082764gb · Cited by 307 · see citing works
Self-citationFetal and umbilical Doppler ultrasound in high-risk pregnancies
Alfirevic, Z., Stampalija, T., & Dowswell, T. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007529.pub4 · Cited by 304 · see citing works
Unbalanced Placental Expression of Imprinted Genes in Human Intrauterine Growth Restriction
McMinn, J. E., Wei, M., Schupf, N., Cusmai, J., Johnson, E., Smith, A. C., Weksberg, R., Thaker, H. M., & Tycko, B. (2005) · Placenta · doi:10.1016/j.placenta.2005.07.004 · Cited by 299 · see citing works
Oxidative Stress, Gene Expression, and Protein Changes Induced in the Human Placenta during Labor
Cindrová‐Davies, T., Yung, H. W., Johns, J., Spasić-Bošković, O., Korolchuk, S., Jauniaux, E. R. M., Burton, G. J., & Jones, D. S. (2007) · American Journal Of Pathology · doi:10.2353/ajpath.2007.070528 · Cited by 296 · see citing works
Self-citationHung, T., Skepper, J. N., & Burton, G. J. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)61778-6 · Cited by 289 · see citing works
Self-citationVelauthar, L., Plana, N., Kalidindi, M., et al. (2013) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.13275 · Cited by 285 · see citing works
Roos, S., Jansson, N., Palmberg, I., Säljö, K., Powell, T. L., & Jansson, T. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.129676 · Cited by 283 · see citing works
Uterine artery Doppler velocimetry in pregnant women with hypertension
Fleischer, A., Schulman, H., Farmakides, G., Bracero, L. A., Grunfeld, L., Rochelson, B. L., & Koenigsberg, M. (1986) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(86)90462-x · Cited by 282 · see citing works
Mayhew, T. M., Ohadike, C., Baker, P. N., Crocker, I. P., Mitchell, C. A., & Ong, S. S. (2003) · Placenta · doi:10.1053/plac.2002.0900 · Cited by 278 · see citing works
Intrauterine growth restriction
(2001) · International Journal of Gynecology & Obstetrics · doi:10.1016/s0020-7292(00)90000-6 · Cited by 277 · see citing works
Jansson, N., Pettersson, J., Haafiz, A., Ericsson, A., Palmberg, I., Tranberg, M., Ganapathy, V., Powell, T. L., & Jansson, T. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.550004 · Cited by 265 · see citing works
The contribution of placental oxidative stress to early pregnancy failure
Hempstock, J., Jauniaux, E. R. M., Greenwold, N., & Burton, G. J. (2003) · Human Pathology · doi:10.1016/j.humpath.2003.08.006 · Cited by 260 · see citing works
Self-citationJansson, T., & Powell, T. L. (2006) · Placenta · doi:10.1016/j.placenta.2005.11.010 · Cited by 257 · see citing works
Placental Phenotypes of Intrauterine Growth
Sibley, C. P., Turner, M. A., Cetin, I., Ayuk, P. T.-Y., Boyd, C. A. R., D'Souza, S. W., Glazier, J. D., Greenwood, S. L., Jansson, T., & Powell, T. L. (2005) · Pediatric Research · doi:10.1203/01.pdr.0000181381.82856.23 · Cited by 250 · see citing works
Intrauterine Growth Restriction: Implications for Placental Metabolism and Transport. A Review
Cetin, I., & Alvino, G. (2009) · Placenta · doi:10.1016/j.placenta.2008.12.006 · Cited by 246 · see citing works
Aardema, M. W., Oosterhof, H., Timmer, A., van Rooy, I., & Aarnoudse, J. G. (2001) · Placenta · doi:10.1053/plac.2001.0676 · Cited by 231 · see citing works
Hempstock, J., Cindrová‐Davies, T., Jauniaux, E. R. M., & Burton, G. J. (2004) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-2-58 · Cited by 229 · see citing works
Self-citationWhitley, G. S. J., & Cartwright, J. E. (2010) · Placenta · doi:10.1016/j.placenta.2010.03.002 · Cited by 213 · see citing works
Review: Placental mitochondrial function and structure in gestational disorders
Holland, O. J., Nitert, M. D., Gallo, L. A., Vejzovic, M., Fisher, J. J., & Perkins, A. V. (2016) · Placenta · doi:10.1016/j.placenta.2016.12.012 · Cited by 208 · see citing works
Review: Trophoblast-Vascular Cell Interactions in Early Pregnancy: How to Remodel a Vessel
Harris, L. K. (2010) · Placenta · doi:10.1016/j.placenta.2009.12.012 · Cited by 203 · see citing works
Human Early Placental Development: Potential Roles of the Endometrial Glands
Burton, G. J., Jauniaux, E. R. M., & Jones, D. S. (2007) · Placenta · doi:10.1016/j.placenta.2007.01.007 · Cited by 203 · see citing works
Self-citationSingle umbilical artery. A statistical analysis of 237 autopsy cases and review of the literature.
Sa, H. (1984) · PubMed · Cited by 199 · see citing works
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics
Bravo, R., Gutierrez, T., Paredes, F., Gatica, D., Rodriguez, A. E., Pedrozo, Z., Chiong, M., Parra, V., Quest, A. F. G., Rothermel, B. A., et al. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2011.10.012 · Cited by 191 · see citing works
Cindrová‐Davies, T., Spasić-Bošković, O., Jauniaux, E. R. M., Jones, D. S., & Burton, G. J. (2007) · American Journal Of Pathology · doi:10.2353/ajpath.2007.061035 · Cited by 190 · see citing works
Self-citationDifferential expression of imprinted genes in normal and IUGR human placentas
Diplas, A. I., Lambertini, L., Lee, M., SPERLING, R. S., Lee, Y. L., Wetmur, J. G., & Chen, J. (2009) · Epigenetics · doi:10.4161/epi.9019 · Cited by 186 · see citing works
Uterine glands: biological roles in conceptus implantation, uterine receptivity and decidualization
Filant, J., & Spencer, T. E. (2014) · The International Journal of Developmental Biology · doi:10.1387/ijdb.130344ts · Cited by 171 · see citing works
Placental Nutrient Transport and Intrauterine Growth Restriction
Gaccioli, F., & Lager, S. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00040 · Cited by 163 · see citing works
Placental pathology of absent and reversed end-diastolic flow in growth-restricted fetuses
Salafia, C., Pezzullo, J. C., MINIOR, V. K., & Divon, M. Y. (1997) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(97)00473-0 · Cited by 162 · see citing works
Yung, H. W., Atkinson, D., Campion‐Smith, T., Olovsson, M., Charnock‐Jones, D. S., & Burton, G. J. (2014) · The Journal of Pathology · doi:10.1002/path.4394 · Cited by 156 · see citing works
Self-citationPlacental mTOR links maternal nutrient availability to fetal growth
Roos, S., Powell, T. L., & Jansson, T. (2009) · Biochemical Society Transactions · doi:10.1042/bst0370295 · Cited by 156 · see citing works
Mitochondrial – Endoplasmic reticulum interactions in the trophoblast: Stress and senescence
Burton, G. J., Yung, H. W., & Murray, A. J. (2016) · Placenta · doi:10.1016/j.placenta.2016.04.001 · Cited by 155 · see citing works
Self-citationLabarrere, C. A., DiCarlo, H. L., Bammerlin, E., Hardin, J. W., Kim, Y. M., Chaemsaithong, P., Haas, D. M., Kassab, G. S., & Romero, R. J. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.12.029 · Cited by 155 · see citing works
Kadyrov, M., Schmitz, C., Black, S., Kaufmann, P., & Huppertz, B. (2003) · Placenta · doi:10.1053/plac.2002.0946 · Cited by 152 · see citing works
The hemodynamics of late-onset intrauterine growth restriction by MRI
Zhu, M. Y., Milligan, N., Keating, S. J., Windrim, R. C., Keunen, J., Thakur, V., Ohman, A., Portnoy, S., Sled, J. G., Kelly, E., et al. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.10.004 · Cited by 149 · see citing works
Jauniaux, E., Jurkovic, D., Campbell, S., et al. (1992) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(92)91678-4 · Cited by 138 · see citing works
Self-citationNishizawa, H., Ota, S., Suzuki, M., Kato, T., Sekiya, T., Kurahashi, H., & Udagawa, Y. (2011) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-9-107 · Cited by 136 · see citing works
The cytotrophoblastic shell and complications of pregnancy
Burton, G. J., & Jauniaux, E. R. M. (2017) · Placenta · doi:10.1016/j.placenta.2017.06.007 · Cited by 136 · see citing works
Self-citationCindrova-Davies, T., Herrera, E. A., Niu, Y., Kingdom, J., Giussani, D. A., & Burton, G. J. (2013) · The American Journal of Pathology · doi:10.1016/j.ajpath.2013.01.001 · Cited by 135 · see citing works
Self-citationRelationship Among Placenta Previa, Fetal Growth Restriction, and Preterm Delivery
Ananth, C. V., Demissie, K., Smulian, J. C., & Vintzileos, A. M. (2001) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01413-2 · Cited by 131 · see citing works
Placental pathology in fetal growth restriction
Vedmedovska, N., Rezeberga, D., Teibe, U., Melderis, I., & Donders, G. G. G. (2010) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2010.11.017 · Cited by 130 · see citing works
Placental histopathology associated with pre‐eclampsia: systematic review and meta‐analysis
Falco, M. L., Sivanathan, J., Laoreti, A., Thilaganathan, B., & Khalil, A. A. (2017) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.17494 · Cited by 130 · see citing works
Increased Autophagy in Placentas of Intrauterine Growth-Restricted Pregnancies
Hung, T., Chen, S., Lo, L., Li, M.-J., Yeh, Y.-L., & Hsieh, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040957 · Cited by 128 · see citing works
Colleoni, F., Padmanabhan, N., Yung, H.-W., Watson, E. D., Cetin, I., Tissot van Patot, M. C., Burton, G. J., & Murray, A. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055194 · Cited by 128 · see citing works
Self-citationHafner, E., Metzenbauer, M., Höfinger, D., Münkel, M., Gassner, R., Schuchter, K., Dillinger‐Paller, B., & Philipp, K. (2003) · Placenta · doi:10.1053/plac.2002.0918 · Cited by 127 · see citing works
Placental surface shape, function, and effects of maternal and fetal vascular pathology
Salafia, C. M., Yampolsky, M., Misra, D. P., Shlakhter, O., Haas, D., Eucker, B., & Thorp, J. M. (2010) · Placenta · doi:10.1016/j.placenta.2010.09.005 · Cited by 126 · see citing works
Usefulness of a placental profile in high-risk pregnancies
Toal, M., Chan, C., Fallah, S., Alkazaleh, F., Chaddha, V., Windrim, R. C., & Kingdom, J. C. (2007) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2006.10.897 · Cited by 126 · see citing works
Centrality of the Umbilical Cord Insertion in a Human Placenta Influences the Placental Efficiency
Yampolsky, M., Salafia, C. M., Shlakhter, O., Haas, D., Eucker, B., & Thorp, J. M. (2009) · Placenta · doi:10.1016/j.placenta.2009.10.001 · Cited by 125 · see citing works
Physiological/pathological ramifications of transcription factors in the unfolded protein responsePreprint
Han, J., & Kaufman, R. J. (2017) · Genes & Development · doi:10.1101/gad.297374.117 · Cited by 119 · see citing works
Sferruzzi-Perri, A. N., Owens, J. A., Pringle, K. G., & Roberts, C. T. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.198622 · Cited by 118 · see citing works
Placental pathology in early intrauterine growth restriction associated with maternal hypertension
Veerbeek, J. H. W., Nikkels, P. G. J., Torrance, H. L., Gravesteijn, J., Uiterweer, E. D. P., Derks, J. B., Koenen, S. V., Visser, G. H. A., van Rijn, B. B., & Franx, A. (2014) · Placenta · doi:10.1016/j.placenta.2014.06.375 · Cited by 117 · see citing works
Ry, F., Pavlova, Z., Benirschke, K., Rh, P., & Ld, P. (1990) · PubMed · Cited by 117 · see citing works
Jauniaux, E. R. M., Ramsay, B., & Campbell, S. (1994) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(94)70397-3 · Cited by 113 · see citing works
Self-citationMadazlı, R., Somunkiran, A., Calay, Z., et al. (2003) · Placenta · doi:10.1053/plac.2002.0945 · Cited by 112 · see citing works
Yung, H. W., Cox, M., van Patot, M. T., & Burton, G. J. (2012) · The FASEB Journal · doi:10.1096/fj.11-190082 · Cited by 112 · see citing works
Self-citationJauniaux, E. R. M., Cindrová‐Davies, T., Johns, J., Dunster, C., Hempstock, J., Kelly, F. J., & Burton, G. J. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031332 · Cited by 111 · see citing works
Self-citationDiffusion-weighted MR Imaging of the Placenta in Fetuses with Placental Insufficiency
Bonél, H., Stolz, B., Diedrichsen, L., Frei, K. A., Saar, B., Tutschek, B., Raio, L., Surbek, D., Srivastav, S., Nelle, M., et al. (2010) · Radiology · doi:10.1148/radiol.10092283 · Cited by 110 · see citing works
Hromadníková, I., Kotlabová, K., Doucha, J., et al. (2012) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2011.11.003 · Cited by 109 · see citing works
Pre-eclampsia and Fetal Growth Restriction: How Morphometrically Different is the Placenta?
Egbor, M., Ansari, T., Morris, N., Green, C. J., & Sibbons, P. D. (2005) · Placenta · doi:10.1016/j.placenta.2005.06.002 · Cited by 109 · see citing works
Naeye, R. L. (1985) · Human Pathology · doi:10.1016/s0046-8177(85)80254-9 · Cited by 103 · see citing works
Burkhardt, T., Schäffer, L., Schneider, C., Zimmermann, R., & Kurmanavičius, J. (2005) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2005.10.032 · Cited by 103 · see citing works
Placental growth patterns affect birth weight for given placental weight
Salafia, C. M., Zhang, J., Miller, R. K., Charles, A. K., Shrout, P., & Sun, W. (2007) · Birth Defects Research Part A: Clinical and Molecular Teratology · doi:10.1002/bdra.20345 · Cited by 103 · see citing works
Higher Mitochondrial DNA Content in Human IUGR Placenta
Lattuada, D., Colleoni, F., Martinelli, A., Garretto, A., Magni, R., Radaelli, T., & Cetin, I. (2008) · Placenta · doi:10.1016/j.placenta.2008.09.012 · Cited by 101 · see citing works
Selenium status in UK pregnant women and its relationship with hypertensive conditions of pregnancy
Rayman, M. P., Bath, S. C., Westaway, J. A. F., Williams, P., Mao, J., Vanderlelie, J. J., Perkins, A. V., & Redman, C. W. G. (2015) · British Journal Of Nutrition · doi:10.1017/s000711451400364x · Cited by 100 · see citing works
The placental factor in early- and late-onset normotensive fetal growth restriction
Kovo, M., Schreiber, L., Ben‐Haroush, A., Cohen, G., Weiner, E., Golan, A., & Bar, J. (2013) · Placenta · doi:10.1016/j.placenta.2012.11.010 · Cited by 99 · see citing works
Maruo, T., Matsuo, H., Murata, K., & Mochizuki, M. (1992) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.75.5.1430098 · Cited by 97 · see citing works
Idiopathic intrauterine growth retardation: Histomorphometry of the human placenta
Teasdale, F. (1984) · Placenta · doi:10.1016/s0143-4004(84)80051-x · Cited by 97 · see citing works
Sebire, N. J., & Fox, H. (2007) · UCL Discovery (University College London) · Cited by 97 · see citing works
The role of the maternal immune system in the regulation of human birthweight
Moffett, A., Hiby, S. E., & Sharkey, A. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0071 · Cited by 94 · see citing works
Parant, O., Capdet, J., Kessler, S., et al. (2009) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2008.06.012 · Cited by 93 · see citing works
Derricott, H., Jones, R. L., & Heazell, A. E. P. (2013) · Placenta · doi:10.1016/j.placenta.2013.07.003 · Cited by 89 · see citing works
Ultrasonographic assessment of placental abnormalities
Jauniaux, E., & Campbell, S. (1990) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(90)90645-n · Cited by 88 · see citing works
Self-citationKovo, M., Schreiber, L., Ben‐Haroush, A., Wand, S., Golan, A., & Bar, J. (2010) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.01.012 · Cited by 87 · see citing works
Intrauterine Growth Restriction and Placental Location
Kalanithi, L. E. G., Illuzzi, J. L., Nossov, V. B., et al. (2007) · Journal of Ultrasound in Medicine · doi:10.7863/jum.2007.26.11.1481 · Cited by 85 · see citing works
In-vivo measurement of intrauterine gases and acid–base values early in human pregnancy
Jauniaux, E. R. M., Watson, A. L., Ozturk, O., Quick, D., & Burton, G. J. (1999) · Human Reproduction · doi:10.1093/humrep/14.11.2901 · Cited by 83 · see citing works
Self-citationVariety in placental shape: When does it originate?
Salafia, C. M., Yampolsky, M., Shlakhter, A., Mandel, D., & Schwartz, N. (2012) · Placenta · doi:10.1016/j.placenta.2011.12.002 · Cited by 81 · see citing works
Akison, L. K., Nitert, M. D., Clifton, V. L., Moritz, K. M., & Simmons, D. G. (2017) · Placenta · doi:10.1016/j.placenta.2017.01.114 · Cited by 81 · see citing works
Mayhew, T. M., Jackson, M. R., & Boyd, P. A. (1993) · Placenta · doi:10.1016/s0143-4004(05)80248-6 · Cited by 80 · see citing works
Maternal floor infarction of the placenta: prenatal diagnosis and clinical significance.
Mandsager, N. T., Bendon, R. W., Mostello, D., et al. (1994) · PubMed · Cited by 79 · see citing works
Human embryonic growth trajectories and associations with fetal growth and birthweight
van Uitert, E. M., Exalto, N., Burton, G. J., Willemsen, S. P., Koning, A. H. J., Eilers, P. H. C., Laven, J. S. E., Steegers, E. A. P., & Steegers‐Theunissen, R. P. M. (2013) · Human Reproduction · doi:10.1093/humrep/det115 · Cited by 79 · see citing works
Self-citationAnomalies of the placenta and umbilical cord in twin gestations
Hubinont, C., Lewi, L., Bernard, P., et al. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.06.054 · Cited by 77 · see citing works
Biswas, S., & Ghosh, S. K. (2008) · Early Human Development · doi:10.1016/j.earlhumdev.2007.09.017 · Cited by 76 · see citing works
Placental Pathologies in Fetal MRI with Pathohistological Correlation
Linduska, N., Dekan, S., Messerschmidt, A., Kasprian, G. J., Brugger, P. C., Chalubinski, K. M., Weber, M., & Prayer, D. (2009) · Placenta · doi:10.1016/j.placenta.2009.03.010 · Cited by 74 · see citing works
Cindrova-Davies, T., van Patot, M. T., Gardner, L., Jauniaux, E., Burton, G. J., & Charnock-Jones, D. S. (2015) · MHR: Basic science of reproductive medicine · doi:10.1093/molehr/gau105 · Cited by 74 · see citing works
Self-citationVoskamp, B. J., Fleurke‐Rozema, H., Oude‐Rengerink, K., Snijders, R. J. M., Bilardo, C. M., Mol, B. W. J., & Pajkrt, E. (2013) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.12541 · Cited by 73 · see citing works
Whitehead, C. L., Walker, S. P., Ye, L., Mendis, S., Kaitu’u‐Lino, T. J., Lappas, M., & Tong, S. Y. C. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2468 · Cited by 71 · see citing works
Arterial blood flow into the human intervillous space
Burchell, R. C. (1967) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(67)90149-4 · Cited by 69 · see citing works
Spinillo, A., Gardella, B., Bariselli, S., Alfei, A., Silini, E. M., & Bello, B. D. (2012) · Prenatal Diagnosis · doi:10.1002/pd.3988 · Cited by 65 · see citing works
Mitra, S. C., Seshan, S. V., & Riachi, L. E. (2000) · The Journal of Maternal-Fetal Medicine · doi:10.1002/1520-6661(200009/10)9:5 · Cited by 64 · see citing works
Burton, G. J., Scioscia, M., & Rademacher, T. W. (2011) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2011.02.005 · Cited by 64 · see citing works
Self-citationEffect of placenta previa on fetal growth
Harper, L. M., Odibo, A. O., Macones, G. A., Crane, J. P., & Cahill, A. G. (2010) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.05.014 · Cited by 63 · see citing works
Jauniaux, E. R. M., Moscoso, G. J., Campbell, S., et al. (1990) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/0028-2243(90)90028-y · Cited by 61 · see citing works
Self-citationIntermittent functioning of the uteroplacental arteries
Martin, C. B., McGaughey, H. S., Kaiser, I. H., Donner, M. W., & Ramsey, E. M. (1964) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(64)90948-2 · Cited by 60 · see citing works
Thamotharan, S., Chu, A., Kempf, K., Janzen, C., Grogan, T., Elashoff, D. A., & Devaskar, S. U. (2017) · PLoS ONE · doi:10.1371/journal.pone.0176493 · Cited by 59 · see citing works
Poidatz, D., Santos, E. D., Duval, F., Moindjie, H., Serazin-Leroy, V., Vialard, F., de Mazancourt, P., & Dieudonné, M. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.05.005 · Cited by 58 · see citing works
Lu, L., Kingdom, J. C., Burton, G. J., & Cindrová‐Davies, T. (2017) · American Journal Of Pathology · doi:10.1016/j.ajpath.2016.12.002 · Cited by 58 · see citing works
Self-citationRemodeling of myometrial radial arteries in preeclampsia
Ong, S. S., Baker, P. N., Mayhew, T. M., & Dunn, W. R. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.08.015 · Cited by 57 · see citing works
Collins, S. L., Birks, J. S., Stevenson, G. N., Papageorghiou, A. T., Noble, J. A., & Impey, L. (2012) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.10149 · Cited by 55 · see citing works
Surviving hypoxia by modulation of mRNA translation rate
Fähling, M. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00875.x · Cited by 54 · see citing works
Endoplasmic reticulum stress responses in placentation - A true balancing act
Bastida-Ruiz, D., Aguilar, E. R. C., Ditisheim, A., Yart, L., & Cohen, M. (2017) · Placenta · doi:10.1016/j.placenta.2017.07.004 · Cited by 54 · see citing works
Investigation of placental circulations by color Doppler ultrasonography
Jauniaux, E. R. M., Jurkovic, D., Campbell, S. C., Kurjak, A., & Hustin, J. (1991) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(11)80005-0 · Cited by 51 · see citing works
Self-citationSuri, S., Muttukrishna, S., & Jauniaux, E. R. M. (2013) · Placenta · doi:10.1016/j.placenta.2013.05.003 · Cited by 51 · see citing works
Self-citationMoran, M., Mulcahy, C., Zombori, G., et al. (2015) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2015.07.023 · Cited by 50 · see citing works
Alkazaleh, F., Chaddha, V., Viero, S., Malik, A., Anastasiades, C., Sroka, H., Chitayat, D. A., Toi, A., Windrim, R. C., & Kingdom, J. C. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.09.010 · Cited by 50 · see citing works
Anjari, A. A., Wright, E., Keating, S. J., Ryan, G., & Kingdom, J. C. (2013) · Prenatal Diagnosis · doi:10.1002/pd.4176 · Cited by 45 · see citing works
Proctor, L., Whittle, W. L., Keating, S. J., et al. (2010) · Placenta · doi:10.1016/j.placenta.2010.10.006 · Cited by 43 · see citing works
Jauniaux, E. R. M., & Hustin, J. (1992) · Histopathology · doi:10.1111/j.1365-2559.1992.tb00424.x · Cited by 43 · see citing works
Self-citationSgambati, E., Biagiotti, R., Marini, M., et al. (2002) · Placenta · doi:10.1053/plac.2002.0793 · Cited by 38 · see citing works
Gruenwald, P. (1961) · PubMed · Cited by 38 · see citing works
Kim, H. J., Kim, J.-H., Chay, D. B., Park, J. H., & Kim, M.-A. (2017) · Obstetrics & Gynecology Science · doi:10.5468/ogs.2017.60.3.266 · Cited by 37 · see citing works
Massive subchorionic thrombohematoma: a series of 10 cases
Fung, T. Y., To, K., Sahota, D. S., et al. (2010) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349.2010.512656 · Cited by 36 · see citing works
Messerschmidt, A., Baschat, A., Linduska, N., et al. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.8891 · Cited by 36 · see citing works
Isolated single umbilical artery: evaluating the risk of adverse pregnancy outcome
Mailáth‐Pokorny, M., Worda, K., Schmid, M. P., Polterauer, S., & Bettelheim, D. (2014) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2014.11.007 · Cited by 36 · see citing works
Macrosomia has its roots in early placental development
Schwartz, N., Quant, H. S., Sammel, M. D., & Parry, S. (2014) · Placenta · doi:10.1016/j.placenta.2014.06.373 · Cited by 35 · see citing works
Prenatal ultrasound diagnosis of massive subchorionic thrombohematoma
RICHARDS, D. S., & Bennett, B. B. (1998) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1998.11050364.x · Cited by 33 · see citing works
Jauniaux, E. R. M., Campbell, S., & Vyas, S. K. (1989) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(89)90663-7 · Cited by 33 · see citing works
Self-citationAssociation of Isolated Single Umbilical Artery With Small for Gestational Age and Preterm Birth
Battarbee, A. N., Palatnik, A., Ernst, L. M., & Grobman, W. A. (2015) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000001037 · Cited by 32 · see citing works
Alkazaleh, F., Viero, S., Simchen, M. J., et al. (2004) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.1044 · Cited by 31 · see citing works
Relationship Between Placental Shape, Cord Insertion, Lobes and Gestational Outcome
Nordenvall, M., Sandstedt, B., & Ulmsten, U. (1988) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016348809004273 · Cited by 31 · see citing works
Implications of placental pathology for disease mechanisms; methods, issues and future approaches
Sebire, N. J. (2016) · Placenta · doi:10.1016/j.placenta.2016.05.006 · Cited by 28 · see citing works
Perinatal outcome of placental massive perivillous fibrin deposition: a case–control study
Devisme, L., Chauvière, C., Franquet‐Ansart, H., Chudzinski, A., Stichelbout, M., Houfflin‐Debarge, V., & Subtil, D. (2017) · Prenatal Diagnosis · doi:10.1002/pd.5013 · Cited by 28 · see citing works
Expansion of placental site and maternal blood supply of primate placentas
Gruenwald, P. (1972) · The Anatomical Record · doi:10.1002/ar.1091730208 · Cited by 27 · see citing works
Aurioles-Garibay, A., Hernandez‐Andrade, E. A., Romero, R. J., Qureshi, F., Ahn, H., Jacques, S. M., Garcia, M., Yeo, L., & Hassan, S. S. (2014) · Fetal Diagnosis and Therapy · doi:10.1159/000357841 · Cited by 26 · see citing works
Khalil, M. I., Sagr, E. R., Elrifaei, R. M., Abdelbasit, O. B., & Halouly, T. A. L. (2013) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2013.09.028 · Cited by 24 · see citing works
Luria, O., Barnea, O., Shalev, J., Barkat, J., Kovo, M., Golan, A., & Bar, J. (2012) · Prenatal Diagnosis · doi:10.1002/pd.3980 · Cited by 24 · see citing works
Kofinas, A. D., Kofinas, G., & Sutija, V. G. (2007) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050701670191 · Cited by 22 · see citing works
Chang, Y., Wang, T., Chang, S., Chao, A., Hsieh, P. C. C., & Wang, C. (2013) · Prenatal Diagnosis · doi:10.1002/pd.4040 · Cited by 19 · see citing works
Expression of placental regulatory genes is associated with fetal growth
Deyssenroth, M. A., Li, Q., Lacasaña, M., et al. (2017) · Journal of Perinatal Medicine · doi:10.1515/jpm-2017-0064 · Cited by 18 · see citing works
Jauniaux, E., GIBB, D. M. F., Moscoso, G. J., et al. (1990) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(90)90626-i · Cited by 16 · see citing works
Self-citationAntenatal diagnosis of placental infarcts by ultrasonography
Jauniaux, E. R. M., & Campbell, S. (1991) · Journal of Clinical Ultrasound · doi:10.1002/jcu.1870190113 · Cited by 13 · see citing works
Self-citationPerinatal outcomes in singleton pregnancies with a single umbilical artery
Naveiro‐Fuentes, M., Badillo, M. P. C., Conde, J. M., Gallo-Vallejo, J. L., & Puertas, A. (2015) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2015.1053864 · Cited by 12 · see citing works
Massive Subchorionic Placental Cyst and Poor Fetal Growth: A Case Report.
Boulis, T. S., Rochelson, B. L., & Williamson, A. K. (2015) · PubMed · Cited by 10 · see citing works
[Ultrasonic study of the single umbilical artery syndrome. A series of 80 cases].
Jauniaux, E. R. M., Demunter, C., Pardou, A., et al. (1989) · PubMed · Cited by 9 · see citing works
Self-citationTheophilou, G., Sahashrabudhe, N., Martindale, E. A., & Heazell, A. E. P. (2012) · Journal of Obstetrics and Gynaecology · doi:10.3109/01443615.2012.702149 · Cited by 8 · see citing works
Basal plate plaque: a novel organising placental thrombotic process
Fitzgerald, B., Shannon, P. T., Kingdom, J. C., et al. (2011) · Journal of Clinical Pathology · doi:10.1136/jcp.2010.086355 · Cited by 8 · see citing works
Levine, A., Frieden, F. J., Stein, J. L., et al. (1993) · Journal of Ultrasound in Medicine · doi:10.7863/jum.1993.12.3.169 · Cited by 7 · see citing works
Ultrasound-diagnosed placental infarction in a woman with recurrent fetal growth restriction
Barclay, D., Evans, K., & Fox, R. (2005) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443610500051825 · Cited by 6 · see citing works
Fetal growth retardation with abnormal blood flows and placental sonographic lesions
Jauniaux, E. R. M., & Campbell, S. C. (1990) · Journal of Clinical Ultrasound · doi:10.1002/jcu.1870180315 · Cited by 6 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 2
- Falco ML, Sivanathan J, Laoreti A, Thilaganathan B, Khalil A. Placental histopa- thology associated with preeclampsia: a sys- tematic review and meta-analysis. Ultrasound Obstet Gynecol 2017;50:295-301.
- Xu C, Bailly-Maitre B, Reed JC. Endo- plasmic reticulum stress: cell life and death de- cisions. J Clin Invest 2005;115:2656-64.
Cited by
Sorted by citations
Martins, J. G., Biggio, J. R., & Abuhamad, A. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.05.010 · Cited by 549 · see citing works
Neonatal Morbidities of Fetal Growth Restriction: Pathophysiology and Impact
Malhotra, A., Allison, B. J., Castillo-Melendez, M., Jenkin, G., Polglase, G. R., & Miller, S. L. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00055 · Cited by 453 · see citing works
Szilagyi, J. T., Avula, V., & Fry, R. C. (2020) · Current Environmental Health Reports · doi:10.1007/s40572-020-00279-0 · Cited by 328 · see citing works
The placenta in fetal growth restriction: What is going wrong?
Sun, C., Groom, K. M., Oyston, C., Chamley, L. W., Clark, A. R., & James, J. L. (2020) · Placenta · doi:10.1016/j.placenta.2020.05.003 · Cited by 253 · see citing works
Roeckner, J. T., Pressman, K., Odibo, L., Duncan, J. R., & Odibo, A. O. (2021) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.23638 · Cited by 60 · see citing works
Fetal growth restriction and stillbirth: Biomarkers for identifying at risk fetuses
King, V. J., Bennet, L., Stone, P. R., Clark, A., Gunn, A. J., & Dhillon, S. K. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.959750 · Cited by 52 · see citing works
Andreasen, L. A., Feragen, A., Christensen, A. N., Thybo, J. K., Svendsen, M. B. S., Zepf, K., Lekadir, K., & Tolsgaard, M. G. (2023) · Scientific Reports · doi:10.1038/s41598-023-29105-x · Cited by 28 · see citing works
Hong, J., Crawford, K., Cavanagh, E., da Silva Costa, F., & Kumar, S. (2024) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.27513 · Cited by 21 · see citing works
Kamga, S. L. S., Ali, I. M., Ngangnang, G. R., Ulucesme, M. C., Keptcheu, L. T. D., Keming, E. M., Tchuenkam, V.-P. K., Foyet, J. V., Aktas, M., Noubom, M., et al. (2024) · Malaria Journal · doi:10.1186/s12936-023-04816-8 · Cited by 15 · see citing works
Li, R., Song, F., Zhou, Q., Wu, W., Cao, Y., Zhang, G., Qian, Z., & Wang, L. (2025) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.29399 · Cited by 10 · see citing works
Sun, H., Jiao, J., Ren, Y., Guo, Y., & Wang, Y. (2023) · Pregnancy Hypertension · doi:10.1016/j.preghy.2022.12.003 · Cited by 10 · see citing works
Long-Term Neurologic Consequences following Fetal Growth Restriction: The Impact on Brain Reserve
Shah, D. K., Pereira, S., & Lodygensky, G. A. (2024) · Developmental Neuroscience · doi:10.1159/000539266 · Cited by 8 · see citing works
Wang, J., Chen, Z., Zhang, H., Li, W., Li, K., Deng, M., & Zou, Y. (2025) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-025-07450-1 · Cited by 9 · see citing works
- Authors
- Burton, G. J., & Jauniaux, E.
- Affiliations
- University of Cambridge (GB)
- University College London (GB)
- Corresponding author
- Burton, Graham J.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2018-02
- Volume
- 218
- Issue
- 2
- Pages
- S745-S761
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2792956190
- Cited by
- 1,070
- References
- 182
- Citations by year
- 2026: 179 · 2025: 130 · 2024: 149 · 2023: 171 · 2022: 138 · 2021: 120 · 2020: 111 · 2019: 49 · 2018: 21
- FWCI
- 12.30
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- placental growth restriction, uteroplacental circulation, spiral artery remodeling, placental malperfusion, placental infarction, fibrin deposition, imprinted gene expression, umbilical artery blood flow, preeclampsia, syncytiotrophoblast, endothelial activation, placental MRI
- MeSH terms
- Chorionic Villi, Female, Fetal Growth Retardation, Gene Expression Regulation, Humans, Magnetic Resonance Imaging, Maternal-Fetal Exchange, Placenta, Placental Insufficiency, Placentation, Pre-Eclampsia, Pregnancy, Stress, Physiological, Trophoblasts, Umbilical Arteries, Ultrasonography, Prenatal, Genomic Imprinting, Placental Circulation, Uterine Artery, Vascular Remodeling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review