A MORPHOLOGICAL STUDY OF THE ENDOCRINE PANCREAS IN HUMAN PREGNANCY
Abstract
Summary: During human pregnancy an enlargement of the islets of Langerhans and hyper‐plasia of the β cells is present. These morphological changes indicate that the endocrine pancreas is able to adapt to the metabolic changes of pregnancy.
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Reduced β-cell hyperplasia may play a role in GDM, based on animal studies and limited post-mortem human studies.
“Reduced β-cell hyperplasia may also play a role in GDM, based on animal studies and limited post-mortem human studies [83].”
From The Pathophysiology of Gestational Diabetes Mellitus (2018) · cites this paper as [83]
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The Pathophysiology of Gestational Diabetes Mellitus
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“Reduced β-cell hyperplasia may also play a role in GDM, based on animal studies and limited post-mortem human studies [83].”
BackgroundBeta Cell Dysfunction and Insulin Resistance
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- Authors
- Van Assche, F. A., Aerts, L., & Prins, F. D.
- Affiliations
- KU Leuven (BE)
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 1978-11
- Volume
- 85
- Issue
- 11
- Pages
- 818-820
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W1993046413
- Cited by
- 267
- References
- 0
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 10 · 2023: 13 · 2022: 16 · 2021: 17 · 2020: 11 · 2019: 15 · 2018: 11 · 2017: 8 · 2016: 8 · 2015: 6 · 2014: 13 · 2013: 13 · 2012: 17
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- endocrine pancreas, pregnancy, pancreatic islets, beta-cell hyperplasia, pancreatic morphology
- MeSH terms
- Adolescent, Adult, Choriocarcinoma, Female, Humans, Hyperplasia, Islets of Langerhans, Pregnancy, Uterine Neoplasms
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