The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Low second trimester maternal serum unconjugated oestriol in pregnancies with Down's syndrome
Abstract
Summary. Second trimester maternal serum unconjugated oestriol levels were measured in the stored serum samples from 22 pregnancies associated with Down's syndrome and 110 unaffected control pregnancies, matched for maternal age, gestational age, duration of storage of the serum sample, smoking habits and maternal weight. The serum unconjugated oestriol level of each affected pregnancy was expressed as a multiple of the median (MoM) of its five matched controls. The unconjugated oestriol levels were significantly lower in the affected pregnancies than in the unaffected pregnancies; the median MoM was 0·79 (P<0·05). This association between low serum unconjugated oestriol and fetal Down's syndrome early in pregnancy raises the possibility that serum unconjugated oestriol measurement may be added to maternal age and alpha‐fetoprotein measurement in the antenatal screening for Down's syndrome.
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Citations
Cites
An association between low maternal serum α-fetoprotein and fetal chromosomal abnormalities
Merkatz, I. R., Nitowsky, H. M., Macri, J. N., & Johnson, W. E. (1984) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(84)90530-1 · Cited by 735
Placental Estrogen Biosynthesis During Human Pregnancy1
SIITERI, P. K., & MACDONALD, P. C. (1966) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-26-7-751 · Cited by 479
Perinatal Problems. The Second Report of the 1958 British Perinatal Mortality Survey
L., Butler, N. R., & Alberman, E. (1970) · Population · doi:10.2307/1530267 · Cited by 187
Effects of smoking on fetoplacental-maternal system during pregnancy
Mochizuki, M., Maruo, T., Masuko, K., & Ohtsu, T. (1984) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(84)90156-x · Cited by 152
Radioimmunoassay of Plasma Estriol
Tulchinsky, D., & Abraham, G. E. (1971) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-33-5-775 · Cited by 124
Hertogh, R. D., Thomas, K. M., Bietlot, Y., Vanderheyden, I., & Ferin, J. (1975) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-40-1-93 · Cited by 105
Cited by
Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities
Nicolaides, K. H. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.03.090 · Cited by 626
Prenatal Screening for Down's Syndrome with Use of Maternal Serum Markers
Haddow, J. E., Palomaki, G. E., Knight, G. J., Williams, J., Pulkkinen, A., Canick, J. A., Saller, D. N., & Bowers, G. B. (1992) · New England Journal of Medicine · doi:10.1056/nejm199208273270902 · Cited by 454
Self-citationAntenatal Screening for Down's Syndrome
Wald, N. J., Kennard, A., Hackshaw, A., & McGuire, A. (1997) · Journal of Medical Screening · doi:10.1177/096914139700400402 · Cited by 406
Self-citationSecond-Trimester Ultrasound to Detect Fetuses With Down Syndrome: A Meta-analysis
Smith-Bindman, R., Hosmer, W., Feldstein, V. A., Deeks, J. J., & Goldberg, J. D. (2001) · JAMA · doi:10.1001/jama.285.8.1044 · Cited by 306
Metadata
- Authors
- CANICK, J. A., KNIGHT, G. J., PALOMAK1, G. E., HADDOW, J. E., CUCKLE, H. S., & WALD, N. J.
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 1988-04
- Volume
- 95
- Issue
- 4
- Pages
- 330-333
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W1993924149
- Cited by
- 306
- References
- 6
- FWCI
- 22.97
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- CANICK, J. A., KNIGHT, G. J., PALOMAK1, G. E., HADDOW, J. E., CUCKLE, H. S., & WALD, N. J. (1988). Low second trimester maternal serum unconjugated oestriol in pregnancies with Down's syndrome. BJOG: An International Journal of Obstetrics & Gynaecology. https://doi.org/10.1111/j.1471-0528.1988.tb06601.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
