Standing at work and preterm delivery
Abstract
Objective Guidelines in some European countries and the United States suggest that pregnant women should avoid prolonged standing and heavy lifting in the workplace during the second and third trimester of pregnancy. However, results from epidemiological studies on this topic are ambiguous. The aim of this study was to evaluate the influence of standing and walking at work in the second trimester on preterm delivery in a population with a low frequency of other workplace hazards. Subjects and design A prospective cohort of 8711 women with singleton pregnancies was established during 1989 through 1991. Information was collected during the 16th week of pregnancy about medical and obstetrical history, general lifestyle factors and exposures at work. The analyses were restricted to 4259 respondents who worked at the 16th week. Potential confounders and effect modifiers were evaluated by stratification and multivariate analyses. Results After adjustment for confounders, women standing more than five hours per work day had an odds ratio (OR) for preterm delivery of 1.2 (95% CI 0.6 to 2.4) compared with women standing two hours or less. For walking, the OR was 1.4 (95% CI 0.7 to 2.5). Many women were unable to separate periods of standing from periods of walking; a combined measure of these two exposures was created to reflect exposure intensity. Women who reported more than five hours of both standing and walking had an adjusted OR of 3.3 (95% CI 1.4 to 8.0) compared with women who reported two hours or less on either of the exposures. No adverse effects were seen for lifting or other types of physical exertion. Conclusions Our findings suggest that standing and walking at work during the second trimester may present a particular risk for preterm delivery, and workplace guidelines are justified. Further research is needed to address the specific mechanisms by which physical exertion, including standing and walking, might cause preterm delivery.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Previous observational studies suggest that various factors (coitus, prolonged standing, infections, physical exertion, caffeine, smoking, cocaine, marijuana, alcohol, skipping meals, psychological stress) may trigger preterm delivery.
“Previous observational studies suggest that coitus7, prolonged standing8,9, urinary tract and other infections10, physical exertion11,12, caffeine intake13, smoking14–16, cocaine use17, marijuana use18, alcohol use17, skipping meals19, and psychological stress20,21 may trigger preterm delivery.”
From Triggers of Spontaneous Preterm Delivery – Why Today? (2014) · cites this paper as [8]
Cites
Kupper, L. L., Hosmer, D. W., & Lemeshow, S. A. (1990) · Journal of the American Statistical Association · doi:10.2307/2290035 · Cited by 7,690 · see citing works
Determinants of low birth weight: methodological assessment and meta-analysis.
Kramer, M. S. (1987) · Europe PMC (PubMed Central) · Cited by 2,682 · see citing works
Modeling and variable selection in epidemiologic analysis
Greenland, S. (1989) · American Journal of Public Health · doi:10.2105/ajph.79.3.340 · Cited by 2,208 · see citing works
The contribution of low birth weight to infant mortality and childhood morbidity
McCormick, M. C. (1985) · New England Journal of Medicine · doi:10.1056/nejm198501103120204 · Cited by 2,119 · see citing works
PREMATURITY AND OCCUPATIONAL ACTIVITY DURING PREGNANCY
MAMELLE, N., Laumon, B., & Lazar, P. (1984) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113750 · Cited by 318 · see citing works
Working During Pregnancy: Effects on the Fetus
Naeye, R. L., & Peters, E. C. (1982) · PEDIATRICS · doi:10.1542/peds.69.6.724 · Cited by 199 · see citing works
NEONATAL MORTALITY RISK IN RELATION TO GESTATIONAL AGE AND BIRTHWEIGHT
Verloove-Vanhorick, S. P., Verwey, R. A., Brand, R., et al. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90713-0 · Cited by 193 · see citing works
Prematurity and work in pregnancy.
McDonald, A. D., McDonald, J. C., Armstrong, B., Cherry, N., Nolin, A. D., & Robert, D. (1988) · Occupational and Environmental Medicine · doi:10.1136/oem.45.1.56 · Cited by 185 · see citing works
EFFECT OF MATERNAL WORK ACTIVITY ON PRETERM BIRTH AND LOW BIRTH WEIGHT
Teitelman, A. M., Welch, L. S., HELLENBRAND, K. G., & Bracken, M. B. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115463 · Cited by 158 · see citing works
The effect of maternal work on fetal growth and duration of pregnancy: a prospective study
LAUNER, L. J., VILLAR, J., KESTLER, E., & DE ONIS, M. (1990) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1990.tb01718.x · Cited by 150 · see citing works
Benefits of Ultrasonic Screening of a Pregnant Population
Grennert, L., Persson, P., Gennser, G. M., & Kullander, S. (1978) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016347809162696 · Cited by 128 · see citing works
Physical activity and the risk of spontaneous preterm delivery.
Berkowitz, G. S., Kelsey, J. L., Tr, H., & Rl, B. (1983) · PubMed · Cited by 124 · see citing works
Pregnant women's working conditions and their changes during pregnancy: a national study in France.
Saurel‐Cubizolles, M., & Kaminski, M. (1987) · Occupational and Environmental Medicine · doi:10.1136/oem.44.4.236 · Cited by 122 · see citing works
Hadders‐Algra, M., Huisjes, H. J., & Touwen, B. C. L. (1988) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1988.tb04775.x · Cited by 116 · see citing works
Birth Weight and Gestational Age in Children With Cerebral Palsy or Seizure Disorders
Ellenberg, J. H. (1979) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1979.02130100068014 · Cited by 107 · see citing works
MATERNAL EMPLOYMENT AND REPRODUCTIVE RISK FACTORS
Savitz, D. A., Whelan, E. A., Rowland, A. S., et al. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115736 · Cited by 107 · see citing works
Biases in Research on Reproduction and Women's Work
Joffe, M. (1985) · International Journal of Epidemiology · doi:10.1093/ije/14.1.118 · Cited by 96 · see citing works
Marbury, M. C., Linn, S., Monson, R. R., et al. (1984) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-198406000-00013 · Cited by 95 · see citing works
MATERNAL ACTIVITY AND BIRTH WEIGHT: A PROSPECTIVE, POPULATION-BASED STUDY
Rabkin, C. S., ANDERSON, H. R., Bland, J. M., BROOKE, O. G., Chamberlain, G. V. P., & Peacock, J. L. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115527 · Cited by 92 · see citing works
Prematurity and Work in Pregnancy
McDonald, A. D., McDonald, J. C., Armstrong, B., Cherry, N., Nolin, A. D., & ROBERT, D. (1988) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-198808000-00007 · Cited by 85 · see citing works
Occupational and socio-medical factors in preterm birth.
Hartikainen-Sorri, A. L., & Sorri, M. (1989) · PubMed · Cited by 72 · see citing works
Work in pregnancy: Its evolving relationship with perinatal outcome (a review)
Saurel‐Cubizolles, M., & Kaminski, M. (1986) · Social Science & Medicine · doi:10.1016/0277-9536(86)90048-1 · Cited by 72 · see citing works
Preterm Birth: Causes, Prevention and Management
Rosen, M. G. (1985) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.52.1.112 · Cited by 70 · see citing works
OCCUPATIONAL WORKING CONDITIONS AND PRETERM BIRTH: A RELIABLE SCORING SYSTEM1
MAMELLE, N., & Munoz, F. (1987) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114649 · Cited by 62 · see citing works
Occupational physical activity and other risk factors for preterm birth among US Army primigravidas.
Ramirez, G., Grimes, R. M., Annegers, J. F., Davis, B. R., & Slater, C. H. (1990) · American Journal of Public Health · doi:10.2105/ajph.80.6.728 · Cited by 58 · see citing works
Impact of Maternal Work Outside the Home During Pregnancy on Neonatal Outcome
ZUCKERMAN, B. S., Frank, D. A., Hingson, R., et al. (1986) · PEDIATRICS · doi:10.1542/peds.77.4.459 · Cited by 55 · see citing works
Women's Physical Activity and Pregnancy Outcome: A Longitudinal Analysis from the Philippines
BARNES, D. L., Adair, L. S., & Popkin, B. M. (1991) · International Journal of Epidemiology · doi:10.1093/ije/20.1.162 · Cited by 54 · see citing works
NORMAL GROWTH OF THE FETAL BIPARIETAL DIAMETER AND THE ABDOMINAL DIAMETER IN A LONGITUDINAL STUDY
Eriksen, P. S., Secher, N. J., & Weis‐Bentzon, M. (1985) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016348509154690 · Cited by 53 · see citing works
Self-citationPhysical work load, fetal development and course of pregnancy.
Nurminen, T., Lusa, S., Ilmarinen, J., et al. (1989) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.1832 · Cited by 51 · see citing works
Pregnant women at work: rest periods to prevent preterm birth?
MAMELLE, N., Bertucat, I., & Munoz, F. (1989) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.1989.tb00366.x · Cited by 50 · see citing works
Suonio, S., Simpanen, A. L., Olkkonen, H., et al. (1976) · PubMed · Cited by 49 · see citing works
Is preterm delivery still related to physical working conditions in pregnancy?
Saurel‐Cubizolles, M., Subtil, D., & Kaminski, M. (1991) · Journal of Epidemiology & Community Health · doi:10.1136/jech.45.1.29 · Cited by 48 · see citing works
Follow-up of preterm children: II. Growth and development at four years of age
Forslund, M., & Bjerre, I. (1990) · Early Human Development · doi:10.1016/0378-3782(90)90141-5 · Cited by 42 · see citing works
Activity Level of Mother??s Usual Occupation and Low Infant Birth Weight
Meyer, B. A., & Daling, J. R. (1985) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-198511000-00019 · Cited by 41 · see citing works
Proposals for a Programmed Prevention Policy of Preterm Birth
Papiernik, E. (1984) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-198409000-00010 · Cited by 41 · see citing works
Antenatal and Perinatal Conditions Correlated to Handicap Among 4-Year-Old Children
Holst, K., Andersen, E., Philip, J., et al. (1989) · American Journal of Perinatology · doi:10.1055/s-2007-999588 · Cited by 40 · see citing works
Relationship of ergonomic stressors to birthweight and gestational age.
Marbury, M. C. (1992) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.1598 · Cited by 40 · see citing works
Rest versus heavy work during the last weeks of pregnancy: influence on fetal growth
Manshande, J. P., Eeckels, R., MANSHANDE‐DESMET, V., & VLIETINCK, R. F. (1987) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1987.tb02290.x · Cited by 35 · see citing works
Effects of Physical Activity and Life-Style Factors on Uterine Contraction Frequency
Grisso, J. A., Main, D. M., Chiu, G. Y., Synder, E., & Holmes, J. H. (1992) · American Journal of Perinatology · doi:10.1055/s-2007-999295 · Cited by 34 · see citing works
The influence of posture upon cardiovascular dynamics throughout pregnancy
Atkins, A. J. F., Watt, J. M., Milan, P., et al. (1981) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/0028-2243(81)90081-2 · Cited by 33 · see citing works
Pregnant women at work: Sociodemographic perspectives
Moss, N., & Carver, K. P. (1993) · American Journal of Industrial Medicine · doi:10.1002/ajim.4700230404 · Cited by 32 · see citing works
Healthy worker effect and pregnancy: role of adverse obstetric history and social characteristics.
Stengel, B., Saurel‐Cubizolles, M., & Kaminski, M. (1987) · Journal of Epidemiology & Community Health · doi:10.1136/jech.41.4.312 · Cited by 23 · see citing works
Premature Contractions: Are They Caused by Maternal Standing?
Schneider, K. T. M., Huch, A., & Huch, R. (1985) · Acta geneticae medicae et gemellologiae · doi:10.1017/s0001566000004694 · Cited by 15 · see citing works
Holmqvist, P., Regefalk, C., & Svenningsen, N. W. (1987) · Journal of Perinatal Medicine · doi:10.1515/jpme.1987.15.1.61 · Cited by 15 · see citing works
Effects of pregnancy on work performance. Council on Scientific Affairs
(1984) · JAMA · doi:10.1001/jama.251.15.1995 · Cited by 9 · see citing works
Maximum Possible Impact of Tocolytics in Preventing Preterm Birth: A Retrospective Assessment
Menticoglou, S. M., Morrison, I., Harman, C. R., et al. (1992) · American Journal of Perinatology · doi:10.1055/s-2007-999273 · Cited by 5 · see citing works
Applicability of Tocolytic Therapy
Zlatnik, F. J. (1992) · American Journal of Perinatology · doi:10.1055/s-2007-999297 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Leisure time physical activity is associated with a reduced risk of preterm delivery
Hegaard, H. K., Hedegaard, M., Damm, P., Ottesen, B., Petersson, K., & Henriksen, T. B. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.08.038 · Cited by 92 · see citing works
Self-citationPhysical Activity and Preterm Birth: A Literature Review
Domingues, M. R., Matijasevich, A., & Barros, A. J. D. (2009) · Sports Medicine · doi:10.2165/11317900-000000000-00000 · Cited by 56 · see citing works
Appropriate technology: antenatal care
Lumbiganon, P. (1998) · International Journal of Gynecology & Obstetrics · doi:10.1016/s0020-7292(98)00189-1 · Cited by 29 · see citing works
Triggers of Spontaneous Preterm Delivery – Why Today?
Hernández‐Díaz, S., Boeke, C. E., Romans, A. T., Young, B., Margulis, A. V., McElrath, T. F., Ecker, J. L., & Bateman, B. T. (2014) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12105 · Cited by 25 · see citing works
- Authors
- Henriksen, T. B., Hedegaard, M., Secher, N. J., & Wilcox, A. J.
- Affiliations
- Aarhus University Hospital (DK)
- National Institutes of Health (US)
- Corresponding author
- Henriksen, Tine Brink
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 1995-03
- Volume
- 102
- Issue
- 3
- Pages
- 198-206
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W2162335605
- Cited by
- 119
- References
- 47
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 1 · 2019: 2 · 2018: 1 · 2017: 5 · 2016: 3 · 2015: 2 · 2014: 6 · 2013: 5 · 2012: 4
- FWCI
- 14.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Occupational Therapy › Occupational Health and Safety in Workplaces
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- preterm birth, second trimester, occupational physical exertion, prenatal exposure, heavy lifting, exposure intensity
- MeSH terms
- Denmark, Female, Gestational Age, Humans, Obstetric Labor, Premature, Occupational Diseases, Posture, Pregnancy, Pregnancy Trimester, Second, Prospective Studies, Risk Factors, Cohort Studies, Odds Ratio, Walking, Lifting
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review