The role of metallobiology and amyloid-β peptides in Alzheimer's disease

Neuroprotection against Aβ and glutamate toxicity by melatonin: Are GABA receptors involved?

Paula-Lima, A. C., Louzada, P. R., Mello, F. G. D., & Ferreira, S. T. (2003) · Neurotoxicity Research · doi:10.1007/bf03033152 · Cited by 53

The same γ‐secretase accounts for the multiple intramembrane cleavages of APP

Zhao, G., Tan, J., Mao, G., Cui, M., & Xu, X. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04302.x · Cited by 52

Structural features of the Cu( ii ) complex with the rat Aβ(1–28) fragment

Gaggelli, E., Grzonka, Z., Kozłowski, H., Migliorini, C., Molteni, E., Valensin, D., & Valensin, G. (2008) · Chemical Communications · doi:10.1039/b713453c · Cited by 52

Deposition of lactoferrin in fibrillar-type senile plaques in the brains of transgenic mouse models of Alzheimer's disease

Wang, L., Sato, H., Zhao, S., & Tooyama, I. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.06.079 · Cited by 50

Iron Status and Stores Decline with Age in Lewis Rats

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Peroxidase Activity of Cyclooxygenase-2 (COX-2) Cross-links β-Amyloid (Aβ) and Generates Aβ-COX-2 Hetero-oligomers That Are Increased in Alzheimer's Disease

Nagano, S., Huang, X., Moir, R. D., Payton, S. M., Tanzi, R. E., & Bush, A. I. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313003200 · Cited by 48

Arsenic Exposure May Be a Risk Factor for Alzheimer’s Disease

Gharibzadeh, S., & Hoseini, S. S. (2008) · Journal of Neuropsychiatry · doi:10.1176/jnp.2008.20.4.501 · Cited by 47

In vitro gamma‐secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc

Hoke, D. E., Tan, J., Ilaya, N. T., Culvenor, J. G., Smith, S. J., White, A. R., Masters, C. L., & Evin, G. M. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04950.x · Cited by 46

The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization

Lee, S., Xue, Y., Hu, J. P., et al. (2011) · Biochemistry · doi:10.1021/bi101846x · Cited by 44

Role of RNA secondary structure of the iron-responsive element in translational regulation of ferritin synthesis

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Serum copper, zinc and copper/zinc ratio in males: influence of aging.

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Metabolic balance studies for zinc and copper in housebound elderly people and the relationship between zinc balance and leukocyte zinc concentrations

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Superoxide dismutase 1 modulates expression of transferrin receptor

Danzeisen, R., Achsel, T., Bederke, U., Cozzolino, M., Crosio, C., Ferri, A., Frenzel, M., Gralla, E. B., Huber, L., Ludolph, A. C., et al. (2006) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-006-0099-4 · Cited by 41

Essential oil composition of sea fennel (Crithmum maritimum) form Turkey

Özcan, M., Akgül, A., Başer, K. H. C., et al. (2001) · Food / Nahrung · doi:10.1002/1521-3803(20011001)45:5 · Cited by 41

Essential Trace Metals and Brain Function

Takeda, A. (2004) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.124.577 · Cited by 40

Dityrosine Cross-Linked Aβ Peptides: Fibrillar β-Structure in Aβ(1-40) Is Conducive to Formation of Dityrosine Cross-Links but a Dityrosine Cross-Link in Aβ(8-14) Does Not Induce β-Structure

Yoburn, J. C., Tian, W., Brower, J. O., Nowick, J. S., Glabe, C. G., & Vranken, D. L. V. (2003) · Chemical Research in Toxicology · doi:10.1021/tx025666g · Cited by 39

Metal‐Binding Properties of the Peptide APP170–188: A Model of the ZnII‐Binding Site of Amyloid Precursor Protein (APP)

Ciuculescu‐Pradines, D., Mekmouche, Y., & Faller, P. (2004) · Chemistry - A European Journal · doi:10.1002/chem.200400786 · Cited by 39

Model studies of cholesterol and ascorbate oxidation by copper complexes: Relevance to Alzheimer’s disease β-amyloid metallochemistry

Hæffner, F., Smith, D. G., Barnham, K. J., & Bush, A. I. (2005) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2005.09.011 · Cited by 34

Mouse Brain Synaptosomes Accumulate Copper-67 Efficiently by Two Distinct Processes Independent of Cellular Prion Protein

Giese, A., Buchholz, M., Herms, J. W., & Kretzschmar, H. A. (2005) · Journal of Molecular Neuroscience · doi:10.1385/jmn:27:3:347 · Cited by 31

From mild cognitive impairment to Alzheimer's disease - influence of homocysteine, vitamin B12 and folate on cognition over time: results from one-year follow-up.

Siuda, J. S., Gorzkowska, A., Patalong‐Ogiewa, M., Krzystanek, E., Czech, E. K., Wiechuła, B. E., Garczorz, W., Danch, A., Jasińska‐Myga, B., & Opala, G. (2009) · PubMed · Cited by 30

Extended study of DETA-functionalized PGMA adsorbent in the selective adsorption behaviors and mechanisms for heavy metal ions of Cu, Co, Ni, Zn, and Cd

Liu, C., & Bai, R. (2010) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2010.04.084 · Cited by 30

Tg-SwDI Transgenic Mice Exhibit Novel Alterations in AβPP Processing, Aβ Degradation, and Resilient Amyloid Angiopathy

Vickle, G. D. V., Esh, C. L., Daugs, I. D., Kokjohn, T. A., Kalback, W. M., Patton, R., Luehrs, D. C., Walker, D. G., Lue, L., Beach, T. G., et al. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.071191 · Cited by 27

Superoxide Dismutase Activity in Cerebrospinal Fluid of Patients with Dementia and Some Other Neurological Disorders

Deyn, P. P. D., Hiramatsu, M., Borggreve, F., Goeman, J., D’Hooge, R., Saerens, J., & Mori, A. (1998) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-199803000-00004 · Cited by 25

Dityrosine Formation in Calmodulin: Conditions for Intermolecular Crosslinking

Malencik, D. A., & Anderson, S. R. (1994) · Biochemistry · doi:10.1021/bi00249a024 · Cited by 23

Zinc Enhances Synthesis of Presenilin 1 in Mouse Primary Cortical Culture

Park, I.-H., Jung, M. W., Mori, H., & Mook‐Jung, I. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5243 · Cited by 23

Assessment of the contribution of inductively coupled plasma mass spectrometry to metalloprotein analysis: a novel approach for studies of multiproteic complexes

Hagège, A., Baldinger, T., Martin-Jouet, M., et al. (2004) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1395 · Cited by 21

Cumulative incidence of vitamin B12 deficiency in patients with Alzheimer disease

Prodan, C. I., Cowan, L. D., Stoner, J. A., & Ross, E. D. (2009) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2009.05.005 · Cited by 21

Effect of transition metals in synaptic damage induced by amyloid beta peptide

Uranga, R. M., Giusto, N. M., & Salvador, G. A. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.07.044 · Cited by 20

Alteration of peripheral markers of copper homeostasis in Alzheimer's disease patients: implications in aetiology and therapy.

Rossi, L. C., Squitti, R., Calabrese, L., Rotilio, G., & Rossini, P. M. (2007) · PubMed · Cited by 18

Is Covalently Crosslinked Aβ Responsible for Synaptotoxicity in Alzheimers Disease?

Naylor, R., Hill, A. F., & Barnham, K. J. (2008) · Current Alzheimer Research · doi:10.2174/156720508786898433 · Cited by 10

Electron paramagnetic resonance analysis of heavy metals in the aging human brain.

Wender, M., Szczech, J., Hoffmann, S. K., et al. (1992) · PubMed · Cited by 10

[Lactoferrin in the central nervous system].

Sacharczuk, M., Zagulski, T., Sadowski, B., et al. (2006) · PubMed · Cited by 10

The plasma membrane redox system in Alzheimer's disease

Adlard, P. A., & Bush, A. I. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.12.009 · Cited by 9

Changes in Plasma Copper and Zinc during Rat Development

Lista, E. M., Solé, J., Arola, L., et al. (2009) · Biology of the Neonate · doi:10.1159/000243969 · Cited by 8

The role of iron in brain ageing and neurodegenerative disorders

Ward, R. J., Zucca, F. A., Duyn, J. H., Crichton, R. R., & Zecca, L. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70117-6 · Cited by 1,819

History and progress of hypotheses and clinical trials for Alzheimer’s disease

Liu, P.-P., Xie, Y., Meng, X.-Y., & Kang, J.-S. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0063-8 · Cited by 723

The application of Ferroptosis in diseases

Qiu, Y., Cao, Y., Cao, W., Jia, Y., & Lu, N. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104919 · Cited by 415

SOD2 in mitochondrial dysfunction and neurodegeneration

Flynn, J. M., & Melov, S. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.05.027 · Cited by 390

Management of oxidative stress and other pathologies in Alzheimer’s disease

Simunkova, M., Alwasel, S. H., Alhazza, I. M., Jomova, K., Kollar, V., Rusko, M., & Valko, M. (2019) · Archives of Toxicology · doi:10.1007/s00204-019-02538-y · Cited by 303

P4‐198: Liposomal delivery of a beta sheet blocker peptide for the treatment of Alzheimer's disease

Kumaraswamy, P., Sethuraman, S., & Krishnan, U. M. (2012) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2012.05.1902 · Cited by 3

A Molecular Dynamics Study on the Binding and Interaction of the Amyloid-Beta (1-42) Peptide with Phospholipid Bilayers

Davis, C. H., & Berkowitz, M. L. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2008.12.2338

Design of peptide-based inhibitor agent against amyloid-β aggregation: Molecular docking, synthesis and in vitro evaluation

Jokar, S., Erfani, M., Bavi, O., Khazaei, S., Sharifzadeh, M. S., Hajiramezanali, M., Beiki, D., & Shamloo, A. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.104050 · Cited by 43

Processing and Secretion of Alzheimer's Disease Amyloid Precursor Protein.

Kinbara, K., KITAGAKI, H., Kinouchi, T., et al. (1994) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.174.209 · Cited by 3

Quantification of the Binding Constant of Copper(II) to the Amyloid-Beta Peptide

Hatcher, L. Q., Hong, L., Bush, W. D., Carducci, T. M., & Simon, J. D. (2008) · The Journal of Physical Chemistry B · doi:10.1021/jp710806s · Cited by 116