The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Endothelin ETA and ETB receptors mediate vascular smooth muscle contraction
Open accessAbstract
We have investigated the receptors mediating endothelin‐induced contraction of rabbit isolated jugular vein (RJV) and rat isolated thoracic aorta (RTA). Endothelin‐1 (ET‐1) and endothelin‐3 (ET‐3) contracted RJV preparations with similar potency (EC 50 values ∼ 1 n m), whereas, ET‐1 (EC 50:4.5 n m) was ∼ 80 fold more potent than ET‐3 in contracting RTA. In addition, the ET B receptor‐selective agonist [Ala 1,3,11,15]ET‐l contracted RJV (EC 50:2.1 n m) but not RTA. The ET A receptor antagonist, BQ123, competitively antagonized (pA 2 6.93) the contraction of RTA produced by ET‐1, but had no effect (at 10 μ m) on the contractile effects of either ET‐1, ET‐3 or [Ala 1,3,11,15]ET‐1 in RJV. These data suggest that both ET A and ET B receptors can mediate vascular smooth muscle contraction.
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Cites
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Mitsui, Y., Yazaki, Y., Goto, K., & Masaki, T. (1988) · Nature · doi:10.1038/332411a0 · Cited by 10,729
SOME QUANTITATIVE USES OF DRUG ANTAGONISTS
ARUNLAKSHANA, O., & SCHILD, H. O. (1959) · British Journal of Pharmacology and Chemotherapy · doi:10.1111/j.1476-5381.1959.tb00928.x · Cited by 3,938
Cloning and expression of a cDNA encoding an endothelin receptor
Arai, H., Hori, S., Aramori, I., Ohkubo, H., & Nakanishi, S. (1990) · Nature · doi:10.1038/348730a0 · Cited by 2,578
Inoue, A., Yanagisawa, M., Kimura, S., Kasuya, Y., Miyauchi, T., Goto, K., & Masaki, T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2863 · Cited by 2,517
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
Sakurai, T., Yanagisawa, M., Takuwat, Y., Miyazakit, H., Kimura, S., Goto, K., & Masaki, T. (1990) · Nature · doi:10.1038/348732a0 · Cited by 2,424
Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor
Ihara, M., Noguchi, K., Saeki, T., Fukuroda, T., Tsuchida, S., Kimura, S., Fukami, T., Ishikawa, K., Nishikibe, M., & Yano, M. (1992) · Life Sciences · doi:10.1016/0024-3205(92)90331-i · Cited by 869
Molecular and cellular mechanism of endothelin regulation. Implications for vascular function.
Masaki, T., Kimura, S., Yanagisawa, M., & Goto, K. (1991) · Circulation · doi:10.1161/01.cir.84.4.1457 · Cited by 393
Venous smooth muscle contains vasoconstrictor ETB-like receptors
Moreland, S., McMullen, D. M., Delaney, C. L., Lee, V. G., & Hunt, J. T. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)91163-k · Cited by 253
[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity
Saeki, T., Ihara, M., Fukuroda, T., Yamagiwa, M., & Yano, M. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91367-l · Cited by 158
Fukuroda, T., Nishikibe, M., Ohta, Y., et al. (1992) · Life Sciences · doi:10.1016/0024-3205(92)90353-q · Cited by 87
Cited by
Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1.
Housset, C., Rockey, D. C., & Bissell, D. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.20.9266 · Cited by 297
Haynes, W. G., Strachan, F. E., & Webb, D. J. (1995) · Circulation · doi:10.1161/01.cir.92.3.357 · Cited by 279
International Union of Pharmacology nomenclature of endothelin receptors.
Masaki, T., Vane, J. R., & Vanhoutte, P. M. (1994) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06781-x · Cited by 256
Déziel, R. A., Ryan, C. L., & Tasker, R. A. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.07.003 · Cited by 30
Metadata
- Authors
- Sumner, M. J., Cannon, T. R., Mundin, J. W., White, D. G., & Watts, I. S.
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 1992-11
- Volume
- 107
- Issue
- 3
- Pages
- 858-860
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- OpenAlex
- W2064946616
- Cited by
- 288
- References
- 10
- FWCI
- 16.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Sumner, M. J., Cannon, T. R., Mundin, J. W., White, D. G., & Watts, I. S. (1992). Endothelin ETA and ETB receptors mediate vascular smooth muscle contraction. British Journal of Pharmacology. https://doi.org/10.1111/j.1476-5381.1992.tb14537.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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