Modifiable risk factors for migraine progression
Abstract
Migraine is a chronic-recurrent disorder that progresses in some individuals. Transformed migraine is the result of this progression. Since migraine does not progress in most patients, identifying the risk factors for progression has emerged as a very important public health priority. If risk factors can be identified, that might provide a foundation for more aggressive preventive intervention. Risk factors for progression may be divided into non-remediable (gender, age, race) and remediable categories. In this paper, we focus on several already identified remediable risk factors, including frequency of migraine attacks, obesity, acute medication overuse, caffeine overuse, stressful life events, depression, and sleep disorders. We present the evidence for each risk factor and discuss possible interventions to address them.
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Depression and/or anxiety in patients with migraine is of major public health significance because these mental health problems are common and result in greater disability and overall worse prognosis than migraine alone.
“Depression and/or anxiety in patients with migraine is of major public health significance because these mental health problems are common and result in greater disability and overall worse prognosis than migraine alone [43, 44].”
From One-Day Acceptance and Commitment Therapy Compared to Support for Depressed Migraine Patients: a Randomized Clinical Trial. (2020) · cites this paper as [44]
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- Authors
- Bigal, M. E., & Lipton, R. B.
- Affiliations
- Albert Einstein College of Medicine (US)
- Venue
- Headache: The Journal of Head and Face Pain
- Publisher
- Wiley
- Published
- 2006-10
- Volume
- 46
- Issue
- 9
- Pages
- 1334-1343
- ISSN
- 0017-8748 (ISSN-L)
- 1526-4610
- OpenAlex
- W2074192427
- Cited by
- 334
- References
- 59
- Citations by year
- 2026: 5 · 2025: 13 · 2024: 22 · 2023: 11 · 2022: 14 · 2021: 19 · 2020: 12 · 2019: 8 · 2018: 18 · 2017: 12 · 2016: 17 · 2015: 12 · 2014: 20 · 2013: 22 · 2012: 14
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Headache The Journal of Head and Face Pain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Migraine and Headache Studies
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Keywords
- migraine progression, chronic migraine, modifiable risk factors, migraine frequency, obesity, life events, depression, sleep disorders, migraine prophylaxis
- MeSH terms
- Anxiety Disorders, Mental Disorders, Bipolar Disorder, Depressive Disorder, Humans, Migraine Disorders, Comorbidity
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