Cited by 105Epilepsy research and treatmentSubstance Abuse Treatment and OutcomesForensic Toxicology and Drug Analysis

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Alcohol and drugs in epilepsy: Pathophysiology, presentation, possibilities, and prevention

Leach, John Paul, Mohanraj, Rajiv, Borland, William·2012·Epilepsia

DOI 10.1111/j.1528-1167.2012.03613.x

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Abstract

Summary: The potentially serious outcomes from ingestion of and dependence on toxins make this an important topic for epileptologists. We must be aware of the potential for harm from compounds that may be freely available, yet patients may try to conceal their use. Problematic compounds may cause seizures either acutely or on withdrawal: Their use may reduce effectiveness of antiepileptic drugs, or may simply promote and enhance chaotic lifestyles. Any or all of these factors may worsen seizure control or even directly cause seizures. This article highlights the pathophysiology behind provoked seizures, provides clues to diagnosis, and then outlines the steps that clinicians should take to reduce the deleterious effects of toxic compounds.

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Kobayashi, T., Ikeda, K., Kojima, H., Niki, H., Yano, R., Yoshioka, T., & Kumanishi, T. (1999) · Nature Neuroscience · doi:10.1038/16019 · Cited by 259
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Alcohol Withdrawal Syndrome
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Show all 91 references

Research works printed but not linked: 2

10.1001/jama.1997.03550020076042 · DOI · Paper page
Scottish Executive Health Department, 2002, Plan for action on alcohol problems

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Authors: Leach, J. P., Mohanraj, R., & Borland, W.
Affiliations: Southern General Hospital (GB)
Salford Royal Hospital (GB)
Gartnavel General Hospital (GB)
Corresponding author: Leach, John Paul
ORCID: Leach, John Paul
Mohanraj, Rajiv
Venue: Epilepsia
Publisher: Wiley
Published: 2012-09
Volume: 53
Issue: s4
Pages: 48-57
ISSN: 0013-9580 (ISSN-L)
1528-1167
DOI: 10.1111/j.1528-1167.2012.03613.x
OpenAlex: W1553610755
Cited by: 105
References: 91
Citations by year: 2026: 3 · 2025: 5 · 2024: 7 · 2023: 5 · 2022: 6 · 2021: 21 · 2020: 11 · 2019: 4 · 2018: 9 · 2017: 8 · 2016: 6 · 2015: 10 · 2014: 7 · 2013: 2 · 2012: 1
FWCI: 0.86
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 3 d)
Locations: Epilepsia (publishedVersion)
PubMed (publishedVersion)
Research Explorer (The University of Manchester) (submittedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
Keywords: alcohol, drugs, epilepsy, provoked seizures, substance use, withdrawal seizures, antiepileptic drug interactions, seizure control, pathophysiology, prevention, diagnosis
MeSH terms: Alcohol Drinking, Ethanol, Alcoholism, Benzodiazepines, Marijuana Abuse, Central Nervous System Depressants, Epilepsy, gamma-Aminobutyric Acid, Heroin Dependence, Humans, Ketamine, Seizures, Substance-Related Disorders, Amphetamine-Related Disorders, Cocaine-Related Disorders, Alcohol Withdrawal Seizures

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Alcohol and drugs in epilepsy: Pathophysiology, presentation, possibilities, and prevention

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