The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Androgens and hair growth
Open accessAbstract
Hair's importance in human communication means that abnormalities like excess hair in hirsutism or hair loss in alopecia cause psychological distress. Androgens are the main regulator of human hair follicles, changing small vellus follicles producing tiny, virtually invisible hairs into larger intermediate and terminal follicles making bigger, pigmented hairs. The response to androgens varies with the body site as it is specific to the hair follicle itself. Normally around puberty, androgens stimulate axillary and pubic hair in both sexes, plus the beard, etc. in men, while later they may also inhibit scalp hair growth causing androgenetic alopecia. Androgens act within the follicle to alter the mesenchyme-epithelial cell interactions, changing the length of time the hair is growing, the dermal papilla size and dermal papilla cell, keratinocyte and melanocyte activity. Greater understanding of the mechanisms of androgen action in follicles should improve therapies for poorly controlled hair disorders like hirsutism and alopecia.
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Cites
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Hibberts, N., Howell, A., & Randall, V. (1998) · Journal of Endocrinology · doi:10.1677/joe.0.1560059 · Cited by 273
Self-citationGeneration of the primary hair follicle pattern.
Mou, C., Jackson, B., Schneider, P., Overbeek, P. A., & Headon, D. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600825103 · Cited by 206
Asada, Y., Sonoda, T., Ojiro, M., Kurata, S., Sato, T., Ezaki, T., & Takayasu, S. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.6.7545 · Cited by 72
Cited by
Escobar-Morreale, H. F., Carmina, E., Dewailly, D., Gambineri, A., Kelestimur, F., Moghetti, P., Pugeat, M., Qiao, J., Wijeyaratne, C. N., Witchel, S. F., et al. (2012) · Human Reproduction Update · doi:10.1093/humupd/dmr042 · Cited by 494
Rahmani, W., Abbasi, S., Hagner, A., Raharjo, E., Kumar, R., Hotta, A., Magness, S., Metzger, D., & Biernaskie, J. (2014) · Developmental Cell · doi:10.1016/j.devcel.2014.10.022 · Cited by 262
Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth
COHEN, J. L. (2010) · Dermatologic Surgery · doi:10.1111/j.1524-4725.2010.01522.x · Cited by 85
Interventions for hirsutism (excluding laser and photoepilation therapy alone)
van Zuuren, E. J., Fedorowicz, Z., Carter, B., & Pandis, N. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010334.pub2 · Cited by 65
Inoue, T., Miki, Y., Abe, K., Hatori, M., Hosaka, M., Kariya, Y., Kakuo, S., Fujimura, T., Hachiya, A., Honma, S., et al. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.05.005 · Cited by 62
Metadata
- Authors
- Randall, V. A.
- Venue
- Dermatologic Therapy
- Publisher
- Wiley
- Published
- 2008-09
- Volume
- 21
- Issue
- 5
- Pages
- 314-328
- ISSN
- 1396-0296 (ISSN-L)
- 1529-8019
- OpenAlex
- W2082100332
- Cited by
- 289
- References
- 7
- FWCI
- 11.41
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
