Cited by 198Pharmaceutical Practices and Patient OutcomesPatient Safety and Medication ErrorsPharmacy and Medical Practices

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Discontinuing medications: a novel approach for revising the prescribing stage of the medication-use process

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Bain, Kevin T., Holmes, Holly M., Beers, Mark H., Maio, Vittorio, Handler, Steven M., Pauker, Stephen G.·2008·Journal of the American Geriatrics Society

DOI 10.1111/j.1532-5415.2008.01916.xPMC PMC3119470

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Abstract

Thousands of Americans are injured or die each year from adverse drug reactions, many of which are preventable. The burden of harm conveyed by the use of medications is a significant public health problem, and therefore, improving the medication-use process is a priority. Recent and ongoing efforts to improve the medication-use process have focused primarily on improving medication prescribing, and not much emphasis has been put on improving medication discontinuation. A formalized approach for rationally discontinuing medications is a necessary antecedent to improving medication safety and improving the nation's quality of care. This article proposes a conceptual framework for revising the prescribing stage of the medication-use process to include discontinuing medications. This framework has substantial practice and research implications, especially for the clinical care of older persons, who are particularly susceptible to the adverse effects of medications.

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Institute of Medicine (2000) · National Academies Press eBooks · doi:10.17226/9728 · Cited by 14,390
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Incidence of Adverse Drug Reactions in Hospitalized Patients: A Meta-analysis of Prospective Studies
Lazarou, J., Pomeranz, B. H., & Corey, P. N. (1998) · JAMA · doi:10.1001/jama.279.15.1200 · Cited by 4,807
Incidence of Adverse Drug Events and Potential Adverse Drug Events: Implications for Prevention
Bates, D. W. (1995) · JAMA · doi:10.1001/jama.1995.03530010043033 · Cited by 2,127
Deficits in Communication and Information Transfer Between Hospital-Based and Primary Care Physicians: Implications for Patient Safety and Continuity of Care
Kripalani, S., LeFevre, F., Phillips, C. O., Williams, M. V., Basaviah, P., & Baker, D. W. (2007) · JAMA · doi:10.1001/jama.297.8.831 · Cited by 2,103
Incidence and Preventability of Adverse Drug Events Among Older Persons in the Ambulatory Setting
Gurwitz, J. H., Field, T. S., Harrold, L. R., Rothschild, J. M., DeBellis, K. R., Seger, A. C., Cadoret, C. A., Fish, L. S., Garber, L., Kelleher, M., et al. (2003) · JAMA · doi:10.1001/jama.289.9.1107 · Cited by 1,666
Effects of Continuing or Stopping Alendronate After 5 Years of Treatment: The Fracture Intervention Trial Long-term Extension (FLEX): A Randomized Trial
Black, D. M., Schwartz, A. V., Ensrud, K. E., Cauley, J. A., Levis, S., Quandt, S. A., Satterfield, S., Wallace, R. B., Bauer, D. C., Palermo, L., et al. (2006) · JAMA · doi:10.1001/jama.296.24.2927 · Cited by 1,407
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Yang, Y., Lewis, J. D., Epstein, S., & Metz, D. C. (2006) · JAMA · doi:10.1001/jama.296.24.2947 · Cited by 1,210
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Dial, S. (2005) · JAMA · doi:10.1001/jama.294.23.2989 · Cited by 954
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Show all 38 references

Research works printed but not linked: 1

Hanlon JT, 2003, Brocklehurst's Textbook of Geriatric Medicine and Gerontology, 1289

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Blom, J. W., Muth, C., Glasziou, P., McCormack, J. P., Perera, R., Poortvliet, R. K. E., Numans, M. E., Thürmann, P., Thiem, U., Thio, S. L., et al. (2020) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2020.07.011 · Cited by 28
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Duque, G., Close, J., Jäger, J., Ebeling, P. R., Inderjeeth, C. A., Lord, S. R., McLachlan, A. J., Reid, I. R., Troen, B. R., & Sambrook, P. N. (2010) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2010.tb03839.x · Cited by 28
Is my older cancer patient on too many medications?
Turner, J. P., Shakib, S., & Bell, J. S. (2016) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2016.10.003 · Cited by 28
Discontinuing Inappropriate Medication in Nursing Home Residents (DIM-NHR Study): protocol of a cluster randomised controlled trial
Wouters, H., Quik, E. H., Boersma, F., Nygård, P., Bosman, J., Böttger, W. M., Mulder, H., Maring, J.-G., Wijma-Vos, L., Beerden, T., et al. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-006082 · Cited by 27
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Hanlon, J. T., Handler, S. M., Maher, R. L., & Schmader, K. E. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6231-8.10104-7 · Cited by 26
Self-citation
Nursing home team-care deprescribing study: a stepped-wedge randomised controlled trial protocol
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Patient attitudes and experiences that predict medication discontinuation in the Veterans Health Administration
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Geriatrician interventions on medication prescribing for frail older people in residential aged care facilities
Poudel, A., Peel, N. M., Mitchell, C., Gray, L., Nissen, L. M., & Hubbard, R. E. (2015) · Clinical Interventions in Aging · doi:10.2147/cia.s84402 · Cited by 23
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Prescribers' perceptions of medication discontinuation: survey instrument development and validation.
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A Delphi process to address medication appropriateness for older persons with multiple chronic conditions
Fried, T. R., Niehoff, K. M., Tjia, J., Redeker, N. S., & Goldstein, M. K. (2016) · BMC Geriatrics · doi:10.1186/s12877-016-0240-3 · Cited by 18
Barriers to and Facilitators of Evidence-Based Decision Making at the Point of Care
O’Malley, A. S., Collins, A., Contreary, K., & Rich, E. C. (2016) · MDM Policy & Practice · doi:10.1177/2381468316660375 · Cited by 17
Tools in polypharmacy
Dovjak, P. (2012) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-012-0362-y · Cited by 17
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Lee, J., Singh, N., Gray, S. L., & Makris, U. E. (2022) · ACR Open Rheumatology · doi:10.1002/acr2.11503 · Cited by 16

Authors: Bain, K. T., Holmes, H. M., Beers, M. H., Maio, V., Handler, S. M., & Pauker, S. G.
Affiliations: University of the Sciences (US)
The University of Texas MD Anderson Cancer Center (US)
Thomas Jefferson University (US)
University of Pittsburgh (US)
Tufts University (US)
ORCID: Holmes, Holly M.
Maio, Vittorio
Handler, Steven M.
Venue: Journal of the American Geriatrics Society
Publisher: Wiley
Published: 2008-10
Volume: 56
Issue: 10
Pages: 1946-1952
ISSN: 0002-8614 (ISSN-L)
1532-5415
DOI: 10.1111/j.1532-5415.2008.01916.x
PMC: PMC3119470
OpenAlex: W2096341024
Cited by: 198
References: 38
Citations by year: 2026: 4 · 2025: 2 · 2024: 8 · 2023: 10 · 2022: 13 · 2021: 14 · 2020: 12 · 2019: 17 · 2018: 12 · 2017: 21 · 2016: 17 · 2015: 13 · 2014: 15 · 2013: 12 · 2012: 14
FWCI: 1.90
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of the American Geriatrics Society (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (KL2TR000146)
National Institute on Aging (L30 AG026830)
National Center for Research Resources (KL2RR024154)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Patient Safety and Medication Errors
Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Keywords: drug discontinuation, medication process, drug prescribing, adverse drug reactions, drug safety, older adults, polypharmacy, conceptual framework, quality of care
MeSH terms: Aged, Aged, 80 and over, Drug Interactions, Drug Therapy, Drug Utilization, Humans, Drug Prescriptions, Substance Withdrawal Syndrome, Polypharmacy, Drug-Related Side Effects and Adverse Reactions

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Discontinuing medications: a novel approach for revising the prescribing stage of the medication-use process

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