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Cited by 374

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Delirium: An Independent Predictor of Functional Decline After Cardiac Surgery

Open access
Rudolph, James L., Inouye, Sharon K., Jones, Richard N., Yang, Frances M., Fong, Tamara G., Levkoff, Sue E., Marcantonio, Edward R.·2010·Journal of the American Geriatrics Society

Abstract

OBJECTIVES: To determine whether patients who developed delirium after cardiac surgery were at risk of functional decline. DESIGN: Prospective cohort study. SETTING: Two academic hospitals and a Veterans Affairs Medical Center. PARTICIPANTS: One hundred ninety patients aged 60 and older undergoing elective or urgent cardiac surgery. MEASUREMENTS: Delirium was assessed daily and was diagnosed according to the Confusion Assessment Method. Before surgery and 1 and 12 months postoperatively, patients were assessed for function using the instrumental activities of daily living (IADL) scale. Functional decline was defined as a decrease in ability to perform one IADL at follow‐up. RESULTS: Delirium occurred in 43.1% (n=82) of the patients (mean age 73.7±6.7). Functional decline occurred in 36.3% (n=65/179) at 1 month and in 14.6% (n=26/178) at 12 months. Delirium was associated with greater risk of functional decline at 1 month (relative risk (RR)=1.9, 95% confidence interval (CI)=1.3–2.8) and tended toward greater risk at 12 months (RR=1.9, 95% CI=0.9–3.8). After adjustment for age, cognition, comorbidity, and baseline function, delirium remained significantly associated with functional decline at 1 month (adjusted RR=1.8, 95% CI=1.2–2.6) but not at 12 months (adjusted RR=1.5, 95% CI=0.6–3.3). CONCLUSION: Delirium was independently associated with functional decline at 1 month and had a trend toward association at 12 months. These findings provide justification for intervention trials to evaluate whether delirium prevention or treatment strategies might improve postoperative functional recovery.

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Metadata

Authors
Rudolph, J. L., Inouye, S. K., Jones, R. N., Yang, F. M., Fong, T. G., Levkoff, S. E., & Marcantonio, E. R.
Venue
Journal of the American Geriatrics Society
Publisher
Wiley
Published
2010-04
Volume
58
Issue
4
Pages
643-649
ISSN
  • 0002-8614 (ISSN-L)
  • 1532-5415
OpenAlex
W1959319786
Cited by
374
References
37
FWCI
14.43
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Delirium: An Independent Predictor of Functional Decline After Cardiac Surgery. https://app.cochat.ai/papers/10.1111/j.1532-5415.2010.02762.x
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Rudolph, J. L., Inouye, S. K., Jones, R. N., Yang, F. M., Fong, T. G., Levkoff, S. E., & Marcantonio, E. R. (2010). Delirium: An Independent Predictor of Functional Decline After Cardiac Surgery. Journal of the American Geriatrics Society. https://doi.org/10.1111/j.1532-5415.2010.02762.x

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