Efficacy of ivabradine in a case of inappropriate sinus tachycardia and ventricular dysfunction
Abstract
We present a case of a 49-year-old man with inappropriate sinus tachycardia and ventricular dysfunction. The conventional treatment (ace-inhibitor and beta-blockers) was not well tolerated by the patient, so Ivabradine, a specific inhibitor of If current in the sinus node, was started. After 3 months of using this medication, we observed an improvement of ejection fraction and quality of life.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Inappropriate sinus tachycardia has been very rarely associated with tachycardia-induced cardiomyopathy in long-standing cases.
“the arrhythmia has been very rarely associated with tachycardia-induced cardiomyopathy in patients with long-standing inappropriate sinus tachycardia.96,97”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [97]
Cites
Fox, K., Ford, I., Steg, P. G., Tendera, M., & Ferrari, R. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61170-8 · Cited by 1,099 · see citing works
Mulder, P. G. H., Barbier, S., Chagraoui, A., Richard, V. J., Henry, J., Lallemand, F., Renet, S., Lerebours, G., Mahlberg‐Gaudin, F., & Thuillez, C. (2004) · Circulation · doi:10.1161/01.cir.0000118464.48959.1c · Cited by 294 · see citing works
Thollon, C., Cambarrat, C., Vian, J., Prost, J.-F. F., Peglion, J. L., & Vilaine, J. P. (1994) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1994.tb13025.x · Cited by 236 · see citing works
Prevalence, characteristics and natural course of inappropriate sinus tachycardia
STILL, A., RAATIKAINEN, P., YLITALO, A., KAUMA, H., IKAHEIMO, M., ANTEROKESANIEMI, Y., & HUIKURI, H. (2005) · Europace · doi:10.1016/j.eupc.2004.12.007 · Cited by 134 · see citing works
BRADY, P. A., LOW, P. A., & SHEN, W. K. (2005) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2005.00227.x · Cited by 98 · see citing works
A case of cardiomyopathy induced by inappropriate sinus tachycardia and cured by ivabradine
WINUM, P., CAYLA, G., RUBINI, M., BECK, L., & MESSNER‐PELLENC, P. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02414.x · Cited by 59 · see citing works
Khan, S., Hamid, S., & Rinaldi, C. A. (2008) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02186.x · Cited by 36 · see citing works
Ivabradine as an Alternative Therapeutic Trial in the Therapy of Inappropriate Sinus Tachycardia
Schulze, V. T., Steiner, S., Hennersdorf, M., & Strauer, B. E. (2007) · Cardiology · doi:10.1159/000111931 · Cited by 36 · see citing works
The Heart Rate‐Lowering Agent Ivabradine Inhibits the Pacemaker Current Ifin Human Atrial Myocytes
Chemaly, A. E., Magaud, C., Patri, S., et al. (2007) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2007.00955.x · Cited by 36 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Katritsis, D. G., Boriani, G., Cosio, F. G., Hindricks, G., Jaïs, P., Josephson, M. E., Keegan, R., Kim, Y.-H., Knight, B. P., Kuck, K.-H., et al. (2017) · Europace · doi:10.1093/europace/euw301 · Cited by 188 · see citing works
Ptaszynski, P., Kaczmarek, K., Ruta, J., Klingenheben, T., & Wranicz, J. K. (2013) · Europace · doi:10.1093/europace/eus204 · Cited by 106 · see citing works
FRANKEL, D. S., LIN, D., ANASTASIO, N., MOUNTANTONAKIS, S. E., DIXIT, S., GERSTENFELD, E. P., HUTCHINSON, M. D., RILEY, M. P., MARCHLINSKI, F. E., & CALLANS, D. J. (2012) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2012.02297.x · Cited by 26 · see citing works
- Authors
- SETTE, A., MARTINO, A., LIOY, E., & CALÒ, L.
- Affiliations
- ASL Roma (IT)
- Corresponding author
- SETTE, ANTONELLA
- ORCID
- CALÒ, LEONARDO
- Venue
- Journal of Cardiovascular Electrophysiology
- Publisher
- Wiley
- Published
- 2010-06-25
- Volume
- 21
- Issue
- 7
- Pages
- 815-817
- ISSN
- 1045-3873 (ISSN-L)
- 1540-8167
- OpenAlex
- W2057871723
- Cited by
- 19
- References
- 9
- Citations by year
- 2025: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2016: 2 · 2015: 1 · 2012: 4
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cardiovascular Electrophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart rate and cardiovascular health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Keywords
- ivabradine, inappropriate sinus tachycardia, ventricular dysfunction, sinoatrial node, ejection fraction, quality of life, beta-blocker intolerance, ACE inhibitor intolerance
- MeSH terms
- Ivabradine, Anti-Arrhythmia Agents, Benzazepines, Electrocardiography, Heart Rate, Humans, Male, Middle Aged, Quality of Life, Stroke Volume, Tachycardia, Sinus, Time Factors, Ventricular Function, Left, Treatment Outcome, Ventricular Dysfunction, Left
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
