CoChat
Sign Up
Cited by 165Gastrointestinal motility and disordersMenstrual Health and DisordersInfant Health and Development

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Symptoms across the menstrual cycle in women with irritable bowel syndrome

Heitkemper, Margaret M., Cain, Kevin C., Jarrett, Monica E., Burr, Robert L., Hertig, Vicky, Bond, Eleanor F.·2003·The American Journal of Gastroenterology
DOI 10.1111/j.1572-0241.2003.07233.x
Open this paper in CoChat — free account

Abstract

OBJECTIVE: The purpose of this study was to describe the patterns of GI, somatic, and psychological symptoms across the menstrual cycle in women with irritable bowel syndrome, and to determine whether symptoms differed by oral contraceptive use or predominant bowel pattern. METHODS: A daily diary was used to assess symptoms across one menstrual cycle. Repeated-measures analysis of covariance, controlling for age and body mass index, was used to compare patterns of symptoms across the menstrual cycle by oral contraceptive use and predominant bowel pattern (diarrhea, constipation, alternating). Data from control women are presented for comparison. RESULTS: For somatic and psychological as well as GI symptoms, women with irritable bowel syndrome had higher symptom severity than did controls. Women with irritable bowel syndrome using oral contraceptives had lower cognitive, anxiety, and depression symptoms (p < 0.05, but not significant after multiple comparison adjustment), but no differences were seen for most symptoms of irritable bowel syndrome. All symptoms except diarrhea were highest in the alternating group and lowest in the diarrhea group, with the constipation group either intermediate or close to the alternating group. This pattern was significant after multiple comparisons adjustment for GI symptoms, and trending toward significance (p < 0.05, but not significant after multiple comparison adjustment) for menstrual, sleep, and cognitive symptoms. The strongest menstrual cycle effect was seen in somatic and menstrual symptoms. The pattern of symptoms over the menstrual cycle did not differ by predominant bowel pattern or by oral contraceptive use. CONCLUSIONS: Many of the symptoms examined differed by predominant bowel pattern and menstrual cycle phase, not just the GI symptoms. The menstrual cycle variation was similar regardless of oral contraceptive use or predominant bowel pattern.

Overview

Integrity signals

Registry

Crossref · 10.1111/j.1572-0241.2003.07233.x

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 7

  1. Donker GA, 1999, Br J Gen Pract, 49, 787
  2. Crowell MD, 1994, Am J Gastroenterol, 89, 1973
  3. Hinds J., 1989, Am J Gastroenterol, 84, 123
  4. Thompson W., 1989, Gastroenterol Int, 2, 92
  5. Drossman D., 2000, Rome II
  6. Jackson N., 1994, Dig Dis Sci, 39, 2607, 10.1007/BF02087697 · DOI
  7. Eliakim R., 2000, J Reprod Med, 45, 781

Cited by

Sorted by citations

See all 165

Related

See all

Metadata

Authors
Heitkemper, M. M., Cain, K. C., Jarrett, M. E., Burr, R. L., Hertig, V., & Bond, E. F.
Affiliations
University of Washington (US)
ORCID
Venue
The American Journal of Gastroenterology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2003-02
Volume
98
Issue
2
Pages
420-430
ISSN
  • 0002-9270 (ISSN-L)
  • 1572-0241
DOI
10.1111/j.1572-0241.2003.07233.x
OpenAlex
W2000031817
Cited by
165
References
32
Citations by year
2026: 2 · 2025: 4 · 2024: 4 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 10 · 2018: 6 · 2017: 6 · 2016: 14 · 2015: 5 · 2014: 8 · 2013: 7 · 2012: 9
FWCI
6.31
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Nursing Research (R01NR004142, NR04142, NR04101)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
Keywords
irritable bowel syndrome, menstrual cycle, oral contraceptives, constipation, diarrhea, somatic symptoms, psychological symptoms, anxiety, depression, cognitive symptoms, sleep symptoms, gastrointestinal symptoms
MeSH terms
Adult, Colonic Diseases, Functional, Constipation, Contraceptives, Oral, Diarrhea, Dysmenorrhea, Female, Humans, Menstrual Cycle, Premenstrual Syndrome, Case-Control Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review