The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Bowel Habit Subtypes and Temporal Patterns in Irritable Bowel Syndrome: Systematic Review
Abstract
UNLABELLED: Irritable bowel syndrome (IBS) is a heterogeneous condition characterized by the presence of abdominal discomfort or pain and bowel habit alterations: constipation (C-IBS), diarrhea (D-IBS), or alternating C and D (A-IBS). Its clinical course is poorly known. OBJECTIVES: (i) To compare bowel habit subtypes distribution in IBS according to sample origin and diagnosis criteria; (ii) To evaluate IBS temporal patterns based on follow-up studies. METHODS: A literature search (1966-2003) was conducted in the MEDLINE and EMBASE databases. A total of 72 studies were found and 22 were finally selected. RESULTS: Population-based studies from the United States (Manning) found similar distribution among C-IBS, D-IBS, and A-IBS, while European studies (Rome I, Rome II, or self-reporting) showed either C-IBS or A-IBS as the most prevalent subtypes. Primary care office-based studies (Rome I or Rome II) showed A-IBS as the most prevalent group. Gastroenterology specialized office-based studies found either C-IBS or D-IBS as the most frequently reported subtype. Prospective follow-up investigations showed that the most frequent IBS temporal pattern profile consists of mild to moderate symptoms appearing in cluster in an intermittent way, about once a week, and lasting 2-5 days on average. CONCLUSION: IBS clinical subtypes distribution differs depending on the population evaluated, the geographical location, and the criteria employed to define IBS and bowel habit subtypes. In most cases, clinical course is characterized by the presence of mild-to-moderate symptoms appearing sequentially. Prospective studies, using clear and stable diagnostic criteria and subtype definitions, and based on daily data collection should further characterize IBS clinical course.
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“Since IBS symptoms are known to vary considerably over time [44], the mean score of four weekly assessments of GSRS-IBS was used to get reliable estimates of the participants' symptom levels at each assessment point.”
Citations
Cites
Functional bowel disorders and functional abdominal pain
Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A. (1999) · Gut · doi:10.1136/gut.45.2008.ii43 · Cited by 2,440
Towards positive diagnosis of the irritable bowel.
Manning, A. P., Thompson, W., Heaton, K. W., & Morris, A. F. (1978) · BMJ · doi:10.1136/bmj.2.6138.653 · Cited by 1,404
Hungin, A. P. S., Whorwell, P. J., Tack, J. F., & Mearin, F. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01456.x · Cited by 774
Self-citationFunctional bowel disorders in apparently healthy people
Thompson, W., & Heaton, K. W. (1980) · Gastroenterology · doi:10.1016/0016-5085(80)90142-0 · Cited by 654
Epidemiology of colonic symptoms and the irritable bowel syndrome
Talley, N. J., Zinsmeister, A. R., van Dyke, C., & Melton, L. J. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90717-y · Cited by 648 · cited 5×
“Eight studies performed in the general population were identified: two in the United States (2, 15) one in the United Kingdom (16), one from France (18), one from Spain (21), one multinational from Europe (20), one from a rural area in Bangladesh (17), and another from Hong-Kong (19).”
BackgroundMethodInfluentialIrritable bowel syndrome in the general population.
Jones, R. H., & LYDEARD, S. (1992) · BMJ · doi:10.1136/bmj.304.6819.87 · Cited by 636
Camilleri, M., Northcutt, A. R., Kong, S., Dukes, G. E., McSorley, D., & Mangel, A. W. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02033-x · Cited by 551
Design of Treatment Trials for Functional Gastrointestinal Disorders
Irvine, E. J., Tack, J., Crowell, M. D., Gwee, K. A., Ke, M., Schmulson, M. J., Whitehead, W. E., & Spiegel, B. (2016) · Gastroenterology · doi:10.1053/j.gastro.2016.02.010 · Cited by 550
Irritable bowel syndrome in general practice: prevalence, characteristics, and referral
Thompson, W. G., Heaton, K. W., Smyth, G. T., & Smyth, C. (2000) · Gut · doi:10.1136/gut.46.1.78 · Cited by 477 · cited 1×
“Available studies in the literature report D-IBS as the most frequent bowel pattern among people seeking health care and even as a predictor of referral to specialists (44, 45).”
BackgroundThe functional gastrointestinal disorders
Olden, K. W. (1997) · General Hospital Psychiatry · doi:10.1016/s0163-8343(96)00109-0 · Cited by 437
Research works printed but not linked: 9
- El-Serag HB, 2003, Rev Gastroenterol Disord, 3, S3
- Thompson WG, 1989, Gastroenterol Int, 2, 92
- Thompson WG, 1999, Gut, 45, 43
- Drossman DA, 2000, Diagnosis, pathophysiology and treatment: A multinational consensus
- 10.1016/S0002-9270(00)01985-7 · DOI
- Bommelaer G, 2002, Gastroenterol Clin Biol, 26, 1118
- Bommelaer G, 1986, Gastroenterol Clin Biol, 10, 7
- Veldhuyzen van Zanten SJ, 1999, Gut, 45, II69
- 10.1080/003655201750153476 · DOI
Cited by
Sorted by citations
Items 101–131 of 131
Irritable Bowel Syndrome in Athletes and Exercise
Heiman, D. L., Lishnak, T. S., & Trojian, T. H. (2008) · Current Sports Medicine Reports · doi:10.1097/01.csmr.0000313396.10064.09 · Cited by 7
“A patient’s predominant pattern may change over time (3).”
BackgroundAlternating bowel pattern: what do people mean?
CHOUNG, R. S., LOCKE, G. R., ZINSMEISTER, A. R., MELTON, L. J., & TALLEY, N. J. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02953.x · Cited by 5
Are floating stools associated with specific functional bowel disorders?
Bouchoucha, M. L., Devroede, G. J., & Benamouzig, R. (2015) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000000380 · Cited by 5
Yang, F., Wu, J., Ye, N.-Y., Miu, J., Yan, J., Liu, L., & Bai, Y. (2021) · Gastroenterology Research and Practice · doi:10.1155/2021/7035557 · Cited by 5
“A subset of IBS-D accounts for nearly 33% of IBS and is often associated with rectal urgency, increased stool frequency, loose/watery stools, and abdominal distension [6].”
BackgroundRetractedTarsitano, F., Castelluzzo, M. A., Concolino, D., & Pensabene, L. (2018) · Current Pediatrics Reports · doi:10.1007/s40124-018-0158-7 · Cited by 4
Xu, J., Luo, J., Shang, L., & Kong, W.-M. (2005) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v13.i19.2332 · Cited by 4
Psychological Treatment of Irritable Bowel Syndrome
Quinton, S., & Keefer, L. (2014) · Wiley eBooks · doi:10.1002/9781118453940.ch22 · Cited by 1
Irritable bowel syndrome (IBS) subtypes: Nothing resembles less an IBS than another IBS
Mearin, F. (2016) · Revista Española de Enfermedades Digestivas · doi:10.17235/reed.2016.4195/2016 · Cited by 5
Self-citationTrastornos funcionales digestivos post-infecciosos: del episodio agudo a la molestia crónica
Mearin, F., & Balboa, A. (2011) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2011.03.016 · Cited by 3
Self-citationProbiotics for the treatment of irritable bowel syndrome in children
Barajas-Nava, L. A., Sánchez, A. C., Castilla-Peón, M. F., Pizarro-Castellanos, M., & Vázquez-Frías, R. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013095 · Cited by 3
Irritable Bowel Syndrome subtypes: constipation, diarrhea…and mixed bowel pattern: Tertium datur
Cremonini, F., & Lembo, A. J. (2013) · Neurogastroenterology & Motility · doi:10.1111/nmo.12274 · Cited by 3
Symptoms and Tests for Irritable Bowel Syndrome: Diagnosing a Complex Disorder
Longstreth, G. F. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.10.025 · Cited by 3
Şen, F., Pınarbaşı, B., İşsever, H., Akyüz, F., Mungan, Z., & Kaymakoğlu, S. (2011) · The Turkish Journal of Gastroenterology · doi:10.4318/tjg.2011.0212 · Cited by 3
Irritable Bowel Syndrome: Pain in Spain
Mearin, F. (2017) · The American Journal of Gastroenterology · doi:10.1038/ajg.2017.429 · Cited by 3
Self-citationIrritable bowel syndrome: pathophysiological and clinical issues
Ivashkin, V. T., & Poluektova, A. A. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 2
Bradette, M., Ar, W., Balshaw, R. F., Kelly, S., Barbeau, M., & Sambrook, R. (2007) · PubMed · Cited by 2
Irritable bowel syndrome in the general population : epidemiology, comorbidity and societal costs
Hillilä, M. T. (2010) · Työväentutkimus Vuosikirja · Cited by 2
Videlock, E. J., & Chang, L. (2015) · Wiley eBooks · doi:10.1002/9781118512074.ch75 · Cited by 2
Comparative evaluation of functional constipation prevention methods in pregnant women
Rybakova, T. N., Nazarova, L. V., Kovalenko, M. S., & Иванович, Т. И. (2022) · GYNECOLOGY · doi:10.26442/20795696.2022.5.201928 · Cited by 1
“Результаты исследования типа фекалий по Бристольской шкале [11] (табл.”
Burden Of Depression Among Individuals With Irritable Bowel Syndrome(IBS) In The Medicaid Population
Bhattacharya, K. (2017) · Cited by 1
Faresjö, Å. (2006) · Cited by 1
Spence, M. (2005) · ResearchSpace (University of Auckland) · Cited by 1
WOMEN WITH IRRITABLE BOWEL SYNDROME Aspects of quality of life and health
Bengtsson, M. (2006) · Lund University Publications (Lund University)
Walter, S. (2006) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Nelson, E. (2012) · Swinburne figshare (Swinburne University of Technology) · doi:10.25916/sut.26271883
Stuhlinkontinenz bei Frauen über 40 Jahren: Wer ist gefährdet?
Varma, M. G., Brown, J. S., Creasman, J. M., Thom, D. H., Eeden, S. K. V. D., Beattie, M. S., & Subak, L. L. (2006) · coloproctology · doi:10.1007/s00053-006-6022-1
Colonic Conditions: Irritable Bowel Syndrome (IBS)
Koerner, C. P., & Sullivan, P. S. (2020) · Springer eBooks · doi:10.1007/978-3-319-65942-8_50
The Psychology of Irritable Bowel Syndrome
Ballou, S., & Keefer, L. (2013) · Wiley eBooks · doi:10.1002/9781394260454.ch21
Role of microbiota-gut-brain axis in migraine and possible interventions
Raikwar, S., & Jain, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-21680-0.00010-9
Alshehri, W. M., Elhady, H. M., Alharbi, A. A., Alshehri, W. A., Albalawi, A., Alkhrissi, N. M., Almutairi, H. A., & Albalawi, A. (2025) · Cureus · doi:10.7759/cureus.88138
“While its precise origins remain unclear, current understanding highlights the significant involvement of subtle inflammation and immune system shifts in the development of IBS-related symptoms [3].”
Metadata
- Authors
- Guilera, M., Balboa, A., & Mearin, F.
- Affiliations
- Hospital Quirón Teknon (ES)
- Corresponding author
- Guilera, Magda
- Venue
- The American Journal of Gastroenterology
- Published
- 2005-05
- Volume
- 100
- Issue
- 5
- Pages
- 1174-1184
- ISSN
- 0002-9270 (ISSN-L)
- 1572-0241
- OpenAlex
- W2021290527
- Cited by
- 131
- References
- 45
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2022: 5 · 2021: 6 · 2020: 2 · 2019: 6 · 2018: 4 · 2017: 8 · 2016: 4 · 2015: 9 · 2014: 15 · 2013: 5 · 2012: 7
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- irritable bowel syndrome, irritable bowel syndrome with constipation, diarrhea-predominant irritable bowel syndrome, clinical course, diagnostic criteria, Rome criteria, Manning criteria, symptom clustering
- MeSH terms
- Constipation, Defecation, Diarrhea, Follow-Up Studies, Humans, Intestines, Prospective Studies, Time Factors, Abdominal Pain, Irritable Bowel Syndrome
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