The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Bacterial osmoadaptation: the role of osmolytes in bacterial stress and virulence
Abstract
Two general strategies exist for the growth and survival of prokaryotes in environments of elevated osmolarity. The 'salt in cytoplasm' approach, which requires extensive structural modifications, is restricted mainly to members of the Halobacteriaceae. All other species have convergently evolved to cope with environments of elevated osmolarity by the accumulation of a restricted range of low molecular mass molecules, termed compatible solutes owing to their compatibility with cellular processes at high internal concentrations. Herein we review the molecular mechanisms governing the accumulation of these compounds, both in Gram-positive and Gram-negative bacteria, focusing specifically on the regulation of their transport/synthesis systems and the ability of these systems to sense and respond to changes in the osmolarity of the extracellular environment. Finally, we examine the current knowledge on the role of these osmostress responsive systems in contributing to the virulence potential of a number of pathogenic bacteria.
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Cites
The complete genome sequence of the gram-positive bacterium Bacillus subtilis.
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Responses of E. coli to osmotic stress: large changes in amounts of cytoplasmic solutes and water
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The effects of osmotic upshock on the intracellular solute pools of Bacillus subtilis
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Cited by
Stress Physiology of Lactic Acid Bacteria.
Papadimitriou, K., Alegría, Á., Bron, P. A., de Angelis, M., Gobbetti, M., Kleerebezem, M., Lemos, J. A., Linares, D. M., Ross, P., Stanton, C., et al. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00076-15 · Cited by 914
Does a rhizospheric microorganism enhance K+ availability in agricultural soils?
Meena, V. S., Maurya, B. R., & Verma, J. P. (2014) · Microbiological Research · doi:10.1016/j.micres.2013.09.003 · Cited by 549
The Many Faces of Glutathione in Bacteria
Masip, L., Veeravalli, K., & Georgiou, G. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.753 · Cited by 477
Responses of microorganisms to osmotic stress.
Bremer, E., & Krämer, R. (2019) · Annual Review of Microbiology · doi:10.1146/annurev-micro-020518-115504 · Cited by 463
Caleb, O. J., Mahajan, P. V., Al-Said, F. A.-J., & Opara, U. L. (2013) · Food and Bioprocess Technology · doi:10.1007/s11947-012-0932-4 · Cited by 346
Metadata
- Authors
- Sleator, R. D., & Hill, C.
- Venue
- FEMS Microbiology Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-03
- Volume
- 26
- Issue
- 1
- Pages
- 49-71
- ISSN
- 0168-6445 (ISSN-L)
- 1574-6976
- OpenAlex
- W2163109978
- Cited by
- 812
- References
- 5
- FWCI
- 10.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sleator, R. D., & Hill, C. (2002). Bacterial osmoadaptation: the role of osmolytes in bacterial stress and virulence. FEMS Microbiology Reviews. https://doi.org/10.1111/j.1574-6976.2002.tb00598.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
