The DOI matches its Crossref record; 203 of the 203 references it cites were found in a registry or an index.
Nuclear lamins: key regulators of nuclear structure and activities
Open accessAbstract
The lamin molecule The supramolecular assembly of lamins Lamin‐binding proteins Lamins and aging Lamins and stem cells Lamins and cancer Lamin and viruses The nuclear lamina is a proteinaceous structure located underneath the inner nuclear membrane (INM), where it associates with the peripheral chromatin. It contains lamins and lamin‐associated proteins, including many integral proteins of the INM, chromatin modifying proteins, transcriptional repressors and structural proteins. A fraction of lamins is also present in the nucleoplasm, where it forms stable complexes and is associated with specific nucleoplasmic proteins. The lamins and their associated proteins are required for most nuclear activities, mitosis and for linking the nucleoplasm to all major cytoskeletal networks in the cytoplasm. Mutations in nuclear lamins and their associated proteins cause about 20 different diseases that are collectively called laminopathies’. This review concentrates mainly on lamins, their structure and their roles in DNA replication, chromatin organization, adult stem cell differentiation, aging, tumorogenesis and the lamin mutations leading to laminopathic diseases.
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Cites
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Cited by
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Genome Architecture: Domain Organization of Interphase Chromosomes
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Miller, K. N., Victorelli, S. G., Salmonowicz, H., Dasgupta, N., Liu, T., Passos, J. F., & Adams, P. D. (2021) · Cell · doi:10.1016/j.cell.2021.09.034 · Cited by 288
Novel roles for A-type lamins in telomere biology and the DNA damage response pathway
Gonzalez‐Suarez, I., Redwood, A. B., Perkins, S. M., Vermolen, B., Lichtensztejin, D., Grotsky, D. A., Morgado‐Palacin, L., Gapud, E. J., Sleckman, B. P., Sullivan, T., et al. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.196 · Cited by 246
Barascu, A., Le Chalony, C., Pennarun, G., Genet, D., Imam, N., Lopez, B., & Bertrand, P. (2012) · The EMBO Journal · doi:10.1038/emboj.2011.492 · Cited by 206
Metadata
- Authors
- Prokocimer, M., Davidovich, M., Nissim‐Rafinia, M., Wiesel‐Motiuk, N., Bar, D. Z., Barkan, R., Meshorer, E., & Gruenbaum, Y.
- Venue
- Journal of Cellular and Molecular Medicine
- Publisher
- Wiley
- Published
- 2009-06
- Volume
- 13
- Issue
- 6
- Pages
- 1059-1085
- ISSN
- 1582-1838 (ISSN-L)
- 1582-4934
- OpenAlex
- W2036970799
- Cited by
- 272
- References
- 203
- FWCI
- 10.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Prokocimer, M., Davidovich, M., Nissim‐Rafinia, M., Wiesel‐Motiuk, N., Bar, D. Z., Barkan, R., Meshorer, E., & Gruenbaum, Y. (2009). Nuclear lamins: key regulators of nuclear structure and activities. Journal of Cellular and Molecular Medicine. https://doi.org/10.1111/j.1582-4934.2008.00676.x
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